LOCUS       NM_001394220            3083 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus cell division cycle 40 (Cdc40), mRNA.
ACCESSION   NM_001394220 XM_039098888
VERSION     NM_001394220.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3083)
  AUTHORS   Bertram,K., Agafonov,D.E., Liu,W.T., Dybkov,O., Will,C.L.,
            Hartmuth,K., Urlaub,H., Kastner,B., Stark,H. and Luhrmann,R.
  TITLE     Cryo-EM structure of a human spliceosome activated for step 2 of
            splicing
  JOURNAL   Nature 542 (7641), 318-323 (2017)
   PUBMED   28076346
REFERENCE   2  (bases 1 to 3083)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 3083)
  AUTHORS   Jurica,M.S., Licklider,L.J., Gygi,S.R., Grigorieff,N. and
            Moore,M.J.
  TITLE     Purification and characterization of native spliceosomes suitable
            for three-dimensional structural analysis
  JOURNAL   RNA 8 (4), 426-439 (2002)
   PUBMED   11991638
REFERENCE   4  (bases 1 to 3083)
  AUTHORS   Lindsey,L.A. and Garcia-Blanco,M.A.
  TITLE     Functional conservation of the human homolog of the yeast pre-mRNA
            splicing factor Prp17p
  JOURNAL   J Biol Chem 273 (49), 32771-32775 (1998)
   PUBMED   9830021
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Apr 8, 2021 this sequence version replaced XM_039098888.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166724.1, SRR26360176.1655126.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-205               JAXUCZ010000020.1  45907774-45907978   c
            206-292             JAXUCZ010000020.1  45893517-45893603   c
            293-422             JAXUCZ010000020.1  45884635-45884764   c
            423-506             JAXUCZ010000020.1  45877187-45877270   c
            507-646             JAXUCZ010000020.1  45875656-45875795   c
            647-743             JAXUCZ010000020.1  45874256-45874352   c
            744-883             JAXUCZ010000020.1  45872396-45872535   c
            884-958             JAXUCZ010000020.1  45871636-45871710   c
            959-1004            JAXUCZ010000020.1  45869656-45869701   c
            1005-1106           JAXUCZ010000020.1  45867713-45867814   c
            1107-1222           JAXUCZ010000020.1  45865938-45866053   c
            1223-1356           JAXUCZ010000020.1  45864764-45864897   c
            1357-1433           JAXUCZ010000020.1  45860050-45860126   c
            1434-1578           JAXUCZ010000020.1  45857978-45858122   c
            1579-3083           JAXUCZ010000020.1  45855739-45857243   c
FEATURES             Location/Qualifiers
     source          1..3083
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q12"
     gene            1..3083
                     /gene="Cdc40"
                     /note="cell division cycle 40"
                     /db_xref="GeneID:361859"
                     /db_xref="RGD:1307063"
     exon            1..205
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..1756
                     /gene="Cdc40"
                     /note="cell division cycle 40 homolog"
                     /codon_start=1
                     /product="pre-mRNA-processing factor 17"
                     /protein_id="NP_001381149.1"
                     /db_xref="GeneID:361859"
                     /db_xref="RGD:1307063"
                     /translation="MSAAIAALAASYGSGSGSESDSDSEGSRCPLPAADSLMHLTKSP
                     SAKPSLTVAVDSAPEVAVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQ
                     QMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYGYALDPSLDNHQVSAKYIGSVEDAE
                     KNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDE
                     ITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSSVPPEKCYL
                     PKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGDRRCLRTFIGHSKA
                     VRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFV
                     AGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIP
                     VDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVA
                     GYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKV
                     ITCGWDGLIKLWD"
     exon            206..292
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     exon            293..422
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     exon            423..506
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     exon            507..646
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     exon            647..743
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     exon            744..883
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     exon            884..958
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     exon            959..1004
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1106
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1222
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..1356
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1433
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     exon            1434..1578
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
     exon            1579..3083
                     /gene="Cdc40"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtatctgtt gcagtcatgt cggctgcgat tgcagctcta gctgcttcct atggctcggg
       61 ttcggggtcc gaatcggact cggacagtga gggcagtcgg tgcccactgc cggccgcgga
      121 ctctctcatg cacttgacca aatcgccttc agccaagccc tctctgacgg tggcggtgga
      181 ctcggctccg gaggtggcag ttaaggaaga tctggagacc ggagttcacc ttgaccctgc
      241 tgtcaaagaa gttcagtata atcctaccta tgagaccatg tttgctcctg agtttggacc
      301 agaaaatccc tttcgaacac agcaaatggc tgcccctcga aatatgcttt ctggatatgc
      361 agagccagca cacatcaacg acttcatgtt cgaacagcag agaaggacat ttgccacata
      421 cggctatgca ctggaccctt cgctagataa tcatcaagtg tctgccaaat acatcggctc
      481 tgtggaagac gctgagaaga accaaggctt aactgttttt gaaactggtc agaagaaaac
      541 agaaaagagg aaaaagttca aagaaaacga tgcatctaat attgatggtt tcttgggacc
      601 gtgggcaaaa tacgtggatg aaaaagatgt ggccaagcct tcagaagaag aacaaaagga
      661 gttggatgaa atcacagcaa agaggcagaa gaaaggcaaa caggaggaag agaagcctgg
      721 ggaggagaag accatcctac atgttaaaga aatgtatgac tatcaaggca ggtcctacct
      781 ccacatccct caggatgttg gtgttaacct gcgctcatct gtgccacctg agaaatgtta
      841 ccttcccaaa aaacaaatcc acgtgtggtc cggacacaca aagggcgtca gtgctgtcag
      901 gctgtttcct ctttccggac atttgttgct gtcttgctcc atggactgta aaattaagct
      961 atgggaagtt tatggagacc ggcgctgtct gagaacattt attggtcaca gtaaagctgt
     1021 gagagacatc tgcttcaaca ctgcaggaac acagttcctc agtgcggcct acgaccggta
     1081 ccttaaactc tgggacaccg agacaggaca gtgtatatca agatttacaa accgcaaagt
     1141 accctattgc gtcaagttca atcccgatga agataagcag aatctctttg tggccgggat
     1201 gtctgataaa aagattgtac agtgggacat tcgcagcgga gagattgttc aagagtacga
     1261 tcggcatttg ggggctgtca acacgattgt ctttgtggat gagaaccgaa gatttgtgag
     1321 tacgtctgat gataaaagcc tacgagtttg ggaatgggat atccctgtgg actttaagta
     1381 catagcagag cctagcatgc actcaatgcc ggcagtgact ttgtctccaa atgggaaatg
     1441 gctagcatgc cagtccatgg ataaccaaat cttaatattt ggagcacaga acagattcag
     1501 attgaataag aagaaaattt ttaagggcca catggtagca ggctatgctt gtcaggtgga
     1561 cttctcacca gacatgagct atgtgatttc gggagatgga aatgggaaat taaacatttg
     1621 ggactggaag accacaaaac tctacagtcg cttcaaagcc catgataaag tgtgcatcgg
     1681 cgccgtgtgg caccctcacg agacgtccaa ggtcatcacg tgcggctggg acggcctcat
     1741 caagctgtgg gattagtggg agtagtcctt tcactgtctg ggatcgtttt tgatccagtg
     1801 tcctatttaa ctatttaatt attaaaacgt gttgggtgac agtttgattt ataggtaatc
     1861 tgttcttaca tggccttatg aggttggcct gttgttttaa gagctttgta aatttgcctc
     1921 agccaagttc ttagcagctt cattttgttc tctctagacg tatatacgtc attcatatga
     1981 gagtgacagg tagtcactgt tggcaggcag ctgcatttgt ccctgtgatg tcactgaaag
     2041 ggtcgtttgt catttttgga gtcaagaaaa aaaatgccta ttggatatga gatcctatgg
     2101 aaaatggcgt agctaacggc tcataaaggc accagacact gtccagtcca ggcaaccagg
     2161 gtggcaagaa caaaggcgga accacccggc tattaccgcc cattgaatca agttcttcct
     2221 cgagttccgt tattttgtat ggccggcttg tctattttta cttgtaaatc agtgaccagg
     2281 ggctgtagct ttcctctaac tatgaagcca tgtaaaatta aaaagcagtc tgtggttcgt
     2341 ttcctaactc tctttccgat ctcagagccg gggctgtgca gacctaagca gaaagcgagg
     2401 ttgtctctga agctggcact gggggagcag ggagcaagcc aggactggga acattacctg
     2461 aaatcactgt ctaaggccct ggcctcgctc tcacaaatca gggccgcagc ctctgccttg
     2521 ccactgggac gaatgataat gagttacctc tggccagact acggcagagt ccaaactatc
     2581 acttggaatt tcttcgaagt cacagttttg tccttaaaat cactctgatt ttgcttgtga
     2641 atataaagag taaaactttt gaatgttaga aaaaattaaa tttcttttca gatctttgaa
     2701 aagccattga cactatcaga aaatgcctgt agcccccgtt ggaaagccgt aaccgtgggg
     2761 agttttcttt ttaaatcacg tgctgaccat tgcactgcct ggcccttgcc atttctgtgt
     2821 cttccaggaa gggtggcata caggaggaaa gaattcatac aaaaactctc tgtcgtccca
     2881 gcacatctta acaaatgtga attactggag tgtagtaaga gaaaggcttc aacaacagta
     2941 ttgcatgtta acgaatcata atttcaagat ctcgatttct cttactgtgt ttttgactgt
     3001 ttctaaacag aataactgta cataaaagtt ttctcctttt tgaaaagatc ctatttttga
     3061 ataaagcatt ctttttatag aaa
//
