LOCUS       NM_001415702            5609 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus cell division cycle 27 (Cdc27), transcript
            variant 1, mRNA.
ACCESSION   NM_001415702 XM_006247535
VERSION     NM_001415702.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5609)
  AUTHORS   Mansfeld,J., Collin,P., Collins,M.O., Choudhary,J.S. and Pines,J.
  TITLE     APC15 drives the turnover of MCC-CDC20 to make the spindle assembly
            checkpoint responsive to kinetochore attachment
  JOURNAL   Nat Cell Biol 13 (10), 1234-1243 (2011)
   PUBMED   21926987
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5609)
  AUTHORS   Song,M.S., Carracedo,A., Salmena,L., Song,S.J., Egia,A.,
            Malumbres,M. and Pandolfi,P.P.
  TITLE     Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a
            phosphatase-independent manner
  JOURNAL   Cell 144 (2), 187-199 (2011)
   PUBMED   21241890
REFERENCE   3  (bases 1 to 5609)
  AUTHORS   Jin,L., Williamson,A., Banerjee,S., Philipp,I. and Rape,M.
  TITLE     Mechanism of ubiquitin-chain formation by the human
            anaphase-promoting complex
  JOURNAL   Cell 133 (4), 653-665 (2008)
   PUBMED   18485873
REFERENCE   4  (bases 1 to 5609)
  AUTHORS   Dube,P., Herzog,F., Gieffers,C., Sander,B., Riedel,D., Muller,S.A.,
            Engel,A., Peters,J.M. and Stark,H.
  TITLE     Localization of the coactivator Cdh1 and the cullin subunit Apc2 in
            a cryo-electron microscopy model of vertebrate APC/C
  JOURNAL   Mol Cell 20 (6), 867-879 (2005)
   PUBMED   16364912
REFERENCE   5  (bases 1 to 5609)
  AUTHORS   Tugendreich,S., Tomkiel,J., Earnshaw,W. and Hieter,P.
  TITLE     CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic
            spindle and is essential for the metaphase to anaphase transition
  JOURNAL   Cell 81 (2), 261-268 (1995)
   PUBMED   7736578
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Dec 23, 2022 this sequence version replaced XM_006247535.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.36380.1,
                                           SRR26643429.39346.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-150               JAXUCZ010000010.1  89949621-89949770   c
            151-226             JAXUCZ010000010.1  89936079-89936154   c
            227-374             JAXUCZ010000010.1  89934093-89934240   c
            375-500             JAXUCZ010000010.1  89930404-89930529   c
            501-598             JAXUCZ010000010.1  89927548-89927645   c
            599-753             JAXUCZ010000010.1  89926741-89926895   c
            754-965             JAXUCZ010000010.1  89926426-89926637   c
            966-1080            JAXUCZ010000010.1  89925206-89925320   c
            1081-1196           JAXUCZ010000010.1  89924141-89924256   c
            1197-1296           JAXUCZ010000010.1  89919864-89919963   c
            1297-1504           JAXUCZ010000010.1  89918532-89918739   c
            1505-1677           JAXUCZ010000010.1  89917774-89917946   c
            1678-1830           JAXUCZ010000010.1  89914840-89914992   c
            1831-2039           JAXUCZ010000010.1  89912879-89913087   c
            2040-2157           JAXUCZ010000010.1  89911064-89911181   c
            2158-2286           JAXUCZ010000010.1  89908157-89908285   c
            2287-2361           JAXUCZ010000010.1  89906085-89906159   c
            2362-2518           JAXUCZ010000010.1  89904844-89905000   c
            2519-5609           JAXUCZ010000010.1  89900676-89903766   c
FEATURES             Location/Qualifiers
     source          1..5609
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..5609
                     /gene="Cdc27"
                     /note="cell division cycle 27"
                     /db_xref="GeneID:360643"
                     /db_xref="RGD:1304921"
     exon            1..150
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     CDS             124..2601
                     /gene="Cdc27"
                     /note="isoform 1 is encoded by transcript variant 1; cell
                     division cycle protein 27 homolog"
                     /codon_start=1
                     /product="cell division cycle protein 27 homolog isoform
                     1"
                     /protein_id="NP_001402631.1"
                     /db_xref="GeneID:360643"
                     /db_xref="RGD:1304921"
                     /translation="MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLL
                     ATCYYRSGKAYKAYRLLKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKS
                     HDDLVTEFGDSACFTLSLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGE
                     KPDPDQTFKLTSLQNFSSCLPNTCTALVSNHSLSHRQPETVLTETPQDTIELNRLNLE
                     SSNSKYSLNTDSSVSYIDSAVISPDNVPLGTGPSILSKQVQNKPKTGRSLLGGPTALS
                     PLTPSFGILPLETPSPGDGSYLQNYTNTPSVIDVPSTGAPTKKSVARMGHTGAKSVFS
                     QSGNSREATPVLVAQTQSSGPQTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKE
                     NSKKLKMKFPPKIPNRKTKSKTNKGGITQPNINDSLEITKLDSSIISEGKISTITPQI
                     QAFNLQKAAAEGLMSLLREMGKGYLALCSYNCKEAINILSHLPSHHYSTGWVLCQIGR
                     AYFELSEYMQAERIFSEVRRIESFRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKN
                     SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALAC
                     FRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHA
                     LKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLV
                     YFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQI
                     MGTDESQESSMTDADDTQLHAAESDEF"
     exon            151..226
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            227..374
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            375..500
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            501..598
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            599..753
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            754..965
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1080
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1196
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1296
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..1504
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            1505..1677
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            1678..1830
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            1831..2039
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            2040..2157
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            2158..2286
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            2287..2361
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            2362..2518
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
     exon            2519..5609
                     /gene="Cdc27"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actcggcctc ccccatcccc cggtaacggt cgctggtgag tttaaatgag ccggggctgg
       61 ccgggctgga gctgctacgg ggggggcctg aggcactgca gaaagtgggt ctgagcctcg
      121 aggatgacgg tgctgcagga acctgtccag gctgctatat ggcaagcact aaaccactat
      181 gcttaccgag acgcagtttt cctcgcagaa cgactatatg cagaagtaca ttcagaagaa
      241 gccttgtttc tactggcgac ctgttactac cgctcaggaa aggcctataa agcctataga
      301 ctcttgaaag gacacagttg taccaccccg cagtgtaaat acctgcttgc aaaatgttgt
      361 gttgacctca gcaagcttgc agaaggggaa caaatcttat ctggtggagt gtttaataag
      421 caaaaaagcc atgacgacct tgtcactgag tttggtgatt cagcttgctt cactctttcc
      481 ttgttgggac atgtatattg caagacagat cggcttgcca aaggatcaga atgttaccaa
      541 aagagcctta gtttaaatcc tttcctctgg tctccctttg aatcgttatg tgaaataggt
      601 gagaagccag atcctgacca aacatttaaa ttaacatctc tacagaattt tagcagttgt
      661 cttcccaaca cgtgtacagc tctagtatct aaccacagtt tatctcacag acagcctgag
      721 acagtcctta cagaaactcc ccaagacacg attgaattaa acagactgaa cttagaatct
      781 tccaattcaa agtactcctt gaatacagat tcctccgtgt cttacattga ttcagctgta
      841 atttcaccag ataacgtccc ccttggaact ggtccttcca tattatctaa acaggttcaa
      901 aataaaccaa aaactggtcg aagtttatta ggaggaccaa ctgctcttag cccattaacc
      961 ccaagttttg ggattttgcc attagaaacc ccaagtcctg gagatggatc ctatttacaa
     1021 aactacacta atacaccttc tgtaattgac gtgccatcca ccggagcacc tactaaaaag
     1081 tccgttgcaa gaatgggcca cactggagcg aagtctgtct tctcacagag tgggaacagt
     1141 cgggaggcca caccggtgct cgttgcccag acacaaagct ctggcccaca aacaagtaca
     1201 acacctcagg tattgagccc cactattaca tctcccccaa atgcattgcc tcgaagaagt
     1261 tcccgccttt tcactagtga cagttctaca accaaggaga atagcaaaaa gttaaaaatg
     1321 aagtttccac ctaaaatccc aaacagaaaa acaaaaagta aaactaataa aggaggaata
     1381 actcaaccca acataaacga tagtctggaa attacaaaat tggactcttc tatcatttca
     1441 gaagggaaaa tatccacaat cacacctcag atccaggcat ttaacctaca aaaggcagca
     1501 gcagaaggtt tgatgagcct tcttcgtgaa atgggaaaag gttatttagc tttgtgttca
     1561 tacaactgca aagaagctat aaatattctg agccacctac cttctcacca ctacagtact
     1621 ggctgggtcc tgtgccagat tggacgggct tattttgaac tttcagaata catgcaggct
     1681 gaaagaatat tctcagaagt tagaaggatt gagagtttca gagttgaggg tatggagatc
     1741 tactctacaa cactctggca tcttcagaaa gatgttgctc tttcggttct ttcaaaagat
     1801 ttaacagaca tggataagaa ttcaccagag gcttggtgtg ctgcagggaa ttgtttcagt
     1861 ctacaacggg agcatgatat agcaattaaa ttcttccaaa gagctatcca ggtggatcca
     1921 aattatgctt atgcctatac tctattagga catgaatttg tgttaactga agaactagat
     1981 aaagcattag catgttttcg aaatgctata agagtaaatc ccagacatta taatgcatgg
     2041 tatggtttag ggatgattta ttacaagcaa gagaaattca gcctcgcaga aatgcatttc
     2101 cagaaagcac ttgatatcaa ccctcagagt tcagttttac tttgccacat tggagtagtt
     2161 cagcatgcac tcaagaagtc tgagaaggct ttggataccc taaacaaagc cattgttata
     2221 gatcccaaga accctctatg caaatttcac agagcctcag ttttatttgc aaatgaaaaa
     2281 tacaagtctg ctttacaaga acttgaagaa ctgaaacaga ttgtccccaa agaatccctc
     2341 gtttacttct taataggaaa ggtttacaag aagttgggtc aaactcatct cgccttgatg
     2401 aatttctctt gggctatgga tttagatcct aaaggagcca ataatcagat taaagaggca
     2461 attgacaagc gctaccttcc agatgatgag gagccgataa cccaggagga gcagatcatg
     2521 ggaacagatg aatcccagga gagcagcatg acagatgcag atgacactca acttcatgca
     2581 gcggaaagtg atgaatttta acttgtggaa gtcagactct gactgtggct agtgctgaca
     2641 tgtttctgtc cctccataca cttgagtctc aactcttgag ccgctattgc cgtcgtttgt
     2701 cacctagacc atgagtgccg ctttcattgg accctgactg cacagaatgg aaggcagtgc
     2761 aatccttagc tgctaacaag actggctctt ttaccagtgt gaatgacaat ttgggggagg
     2821 ggtgaggaac ttttcttttt ttctttaatc tcctcagttg gaaatctatc atggaaggaa
     2881 gagttatgtt ttatcttgaa ggaaccgtta gatatgggaa tggtgatgaa ccagaatttc
     2941 ttggtcattt ttccaaaatt gttttttatt tggttctatt cctgataaac agagtgactg
     3001 accttcattt ctaggttctt caagaatggt gttagcaagt gccagatgga acaataaaag
     3061 acgttgcctg taacagagta aagttcattg ccaaggaaat agcttacctt aagcaaatgc
     3121 agtgggcctg tttggactca tatgtaggag tcaaatatcc ctccatacag tgtacacttt
     3181 aatgtctaac caagaatttt aatttattat cttgcttcaa agtgttgatc attgctgtct
     3241 tggtattgga aactttaaaa ttggtcttga caatactggc tttactcttt gagctcggtg
     3301 ggattgcctt caacactcaa gagatggtag agtttttccc ggatgaaaag ccaagcaggc
     3361 ccttaataac cactgtgttt accagaagaa tcagtatgag aacactaaag agagaccttc
     3421 gagatcatgg tgaagaagcc ttaatacagt tggagctgta cctaaccgtg agtctgcctc
     3481 tttcccagga gtgcaagaac gtgtggtgcc ctctgtggag gtcagggccg ttcttttcag
     3541 ctctctgctt cgtattgtca gtgtgagtca ccacaacttg taatgagcgt cattaattgg
     3601 gtttaaaaat actgaaaatt tttagcctag ggaaaagttt cttatgaaag agacattctc
     3661 ttctgagatc atcataatat gggtttgtgt gtttgggaac tggccacaat tttaaagatc
     3721 taattatgca tataaaatgg gaattattgg aatttcacag gaacagattt aaacagtctt
     3781 aaattgtgta tctcctttat tgtaatgtat tgaaaatttt agagaaactt tagttaacat
     3841 tttattaagt gccaatgtca gaatataaca aattatagtt tcttatgagt gacaggccta
     3901 cagttattat tttggaatat ttgatgaagg aaaagcttac ccactggtta cttgtatatg
     3961 taagtcaaac tgtgaagata aggtggatta caaaagctgt ggaaagaatg ttttagcctg
     4021 tagactcagt cctttcctgt cagttactta atctcctcat gcagatgtga attagatgcc
     4081 actataaagt ccaagtcttg ggttagggat tagatgccag ggaaacattt cctgcctaaa
     4141 tctatgtatg tgtgccgttc aaaaaaaaat aatttatgtg gaaaaggaaa gttgggaata
     4201 aatgactatc ataaaaaatt cccataggct agcacttcaa ttccatttta ttgttcatta
     4261 gttatgtaaa gcttaatttt catttctttt atttttttaa tcagcgaatc ataagacagc
     4321 tatatacata tatattacat catcagatct agagtttcat agaaggcttt accctgagtt
     4381 ctgttgcata cctagagaaa gccaagctca gagcagaatt gtcagagtgt aattatcttc
     4441 ttttagtagg aatttatgtc ctgtgccaga ggaactttct ggtgctgatt tcaagacaaa
     4501 ggaaggggtc attgtagttg tggctgtggc tggctgaaag gcaggtacac agacacttgg
     4561 cctgctggca ctttcctcac tcctgcttct gacagcattt acataaggaa gccttatttc
     4621 cacatagtga ctgtttcttg ggtttctttt tctttgtgtc tttgctcttt tttttttttt
     4681 ttttttttta atttcttttt cacagaatag ggatcaacta aacaaacaca ttttggtaag
     4741 caaattgttt caaatttcag accttgcttt gaaggaaatt aagaatacta aagacttcac
     4801 cgtctttttc acacctatac ataagtatat ggatacaaat acacacagtc acacagaagt
     4861 atattagagc attggatttc attttcctca tggaaatggt tattactata ccaggatgta
     4921 tatttttttc aggagaacag atggtactca gaataaggaa aggtgggtct cttaactttt
     4981 cctgtatttc attacttaca ttttttattt tatccaagaa ctgcaagtaa catttgaacc
     5041 atgctgctgt tgtaccttaa aaactcagtg ataaccagtg tttagtcgat taaaagcact
     5101 cttttcgaag aaaacagttt taaagtctct gattagccag agtacagttt gggtcttcac
     5161 tgagaaaaat gatggcccat tttctttggg aaaccctggg aaatgcaagt gtgggtgtgc
     5221 catgtgtgtt ctatttgcat tgaaacaatg tacctttgtg tcgtcttttt gcttttcctg
     5281 acttatttca gaaattgtat agtctttggg ggggaaaaag tcttttctgt taatatattt
     5341 acagttcatt aaaggatatg gaaaatccaa ataaattact tttgaaagca gtttataatc
     5401 aaggtgttaa agctatgtaa aagctgtgtc atctgcattt ttatagtgag tcacagcagc
     5461 atagtaatga aagatcacat tttatgttct acaggagcct aggacaatgt ttctctaatt
     5521 tttacttaca ctttttaata tatatatatt aaaattcata ccctttttag tattatttgg
     5581 aatttcaaaa taaatattat gacaaaaaa
//
