LOCUS       NM_001100659            3281 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus cell division cycle 23 (Cdc23), mRNA.
ACCESSION   NM_001100659 XM_001061467 XM_214588
VERSION     NM_001100659.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3281)
  AUTHORS   Mansfeld,J., Collin,P., Collins,M.O., Choudhary,J.S. and Pines,J.
  TITLE     APC15 drives the turnover of MCC-CDC20 to make the spindle assembly
            checkpoint responsive to kinetochore attachment
  JOURNAL   Nat Cell Biol 13 (10), 1234-1243 (2011)
   PUBMED   21926987
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3281)
  AUTHORS   Jin,L., Williamson,A., Banerjee,S., Philipp,I. and Rape,M.
  TITLE     Mechanism of ubiquitin-chain formation by the human
            anaphase-promoting complex
  JOURNAL   Cell 133 (4), 653-665 (2008)
   PUBMED   18485873
REFERENCE   3  (bases 1 to 3281)
  AUTHORS   Dube,P., Herzog,F., Gieffers,C., Sander,B., Riedel,D., Muller,S.A.,
            Engel,A., Peters,J.M. and Stark,H.
  TITLE     Localization of the coactivator Cdh1 and the cullin subunit Apc2 in
            a cryo-electron microscopy model of vertebrate APC/C
  JOURNAL   Mol Cell 20 (6), 867-879 (2005)
   PUBMED   16364912
REFERENCE   4  (bases 1 to 3281)
  AUTHORS   Kraft,C., Herzog,F., Gieffers,C., Mechtler,K., Hagting,A., Pines,J.
            and Peters,J.M.
  TITLE     Mitotic regulation of the human anaphase-promoting complex by
            phosphorylation
  JOURNAL   EMBO J 22 (24), 6598-6609 (2003)
   PUBMED   14657031
REFERENCE   5  (bases 1 to 3281)
  AUTHORS   Zhao,N., Lai,F., Fernald,A.A., Eisenbart,J.D., Espinosa,R.,
            Wang,P.W. and Le Beau,M.M.
  TITLE     Human CDC23: cDNA cloning, mapping to 5q31, genomic structure, and
            evaluation as a candidate tumor suppressor gene in myeloid
            leukemias
  JOURNAL   Genomics 53 (2), 184-190 (1998)
   PUBMED   9790767
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On or before Oct 13, 2007 this sequence version replaced
            XM_001061467.1, XM_214588.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643287.34644.1,
                                           SRR26643285.51773.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760393 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-419               JAXUCZ010000018.1  26532243-26532661   c
            420-492             JAXUCZ010000018.1  26532086-26532158   c
            493-630             JAXUCZ010000018.1  26529315-26529452   c
            631-673             JAXUCZ010000018.1  26526300-26526342   c
            674-779             JAXUCZ010000018.1  26525709-26525814   c
            780-912             JAXUCZ010000018.1  26525478-26525610   c
            913-1090            JAXUCZ010000018.1  26521081-26521258   c
            1091-1188           JAXUCZ010000018.1  26520906-26521003   c
            1189-1270           JAXUCZ010000018.1  26520705-26520786   c
            1271-1424           JAXUCZ010000018.1  26516964-26517117   c
            1425-1544           JAXUCZ010000018.1  26516712-26516831   c
            1545-1620           JAXUCZ010000018.1  26516423-26516498   c
            1621-1682           JAXUCZ010000018.1  26516019-26516080   c
            1683-1761           JAXUCZ010000018.1  26514719-26514797   c
            1762-1881           JAXUCZ010000018.1  26514524-26514643   c
            1882-3281           JAXUCZ010000018.1  26512894-26514293   c
FEATURES             Location/Qualifiers
     source          1..3281
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p12"
     gene            1..3281
                     /gene="Cdc23"
                     /note="cell division cycle 23"
                     /db_xref="GeneID:291689"
                     /db_xref="RGD:1304819"
     exon            1..419
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     CDS             259..2052
                     /gene="Cdc23"
                     /note="CDC23 (cell division cycle 23, yeast, homolog)"
                     /codon_start=1
                     /product="cell division cycle protein 23 homolog"
                     /protein_id="NP_001094129.1"
                     /db_xref="GeneID:291689"
                     /db_xref="RGD:1304819"
                     /translation="MAANSSVVSVAAAATTVPGVSTVADFSDLREIKKQLLLIAGLTR
                     ERGLLHSSKWSAELAFSLPALPLSELQPPPPLTEEDAQDVDAYTLAKAYFDVKEYDRA
                     AHFLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSR
                     KHQARGLDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEM
                     LKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQHLIDVGFSKSSYIVSQIAVAYHNI
                     RDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETC
                     CVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAI
                     EVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLV
                     EAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCGETVEHLE
                     ESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRNQGETPTSD
                     TPGTFFLPASLSANNTPTRRVSPLNLSSVTP"
     exon            420..492
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            493..630
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            631..673
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            674..779
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            780..912
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1090
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1188
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            1189..1270
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..1424
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            1425..1544
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            1545..1620
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            1621..1682
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            1683..1761
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            1762..1881
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
     exon            1882..3281
                     /gene="Cdc23"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tttttttttt tttatgctgg gatgcctcag tccgtgcccg cctctccctt tcacttcttg
       61 ttctaattta cctccctcag cagctcttgc caatcaggat ctaactgtct ctttttccca
      121 ttgccttttc ggaaccttac gatgaaggtt tgtgattggt tgttccgagc aaggctagac
      181 caataagagg cagaagtttt cgcttccgcg gagcaagtat tgttgccgct gattggctgg
      241 agcggccgag ggaggaaaat ggctgcgaat tcttcggtag tctcggtggc agcggccgcc
      301 acgacggtgc cgggcgtgtc cactgtcgcg gatttctcag acttgcggga aattaaaaag
      361 cagctgctgc tcatcgcggg cctcactcgg gagcggggcc tgctgcacag cagcaaatgg
      421 tctgcggagt tggccttctc tctgcccgcc ttgcctttgt ctgagctgca gccgccgccg
      481 cctcttacag aggaggatgc acaggatgtg gatgcttaca ccctggccaa ggcctacttt
      541 gacgttaaag agtatgaccg ggcagcacat ttcctgcatg gctgtaatag caagaaagcc
      601 tatttcctgt acatgtattc cagatacctg tctggagaga agaagaagga tgacgaaaca
      661 gtcgatagcc taggacccct agaaaaagga caagtcaaaa acgaggctct ccgagaactg
      721 agagtggaac tcagcaggaa gcaccaagct aggggacttg atgggttcgg cctttacctg
      781 tatggggtgg tgcttcggaa actggactta gtgaaagagg ctattgatgt gtttgtggag
      841 gctactcatg ttctgccctt gcactggggg gcctggttgg agctgtgtaa cctgatcaca
      901 gacaaagaga tgctgaagtt cctgtctttg cctgacacct ggatgaagga gttcttcttg
      961 gctcacatat acacagaatt gcagctgata gaggaggcct tgcagaagta ccagcatctc
     1021 attgacgtgg gcttttccaa gagctcatac attgtttccc aaatcgcagt tgcctatcac
     1081 aatatcagag atatcgacaa agccctttct attttcaatg agctgaggaa acaagatcct
     1141 tacaggattg aaaatatgga cacgttctcc aaccttctct atgtcaggag catgaagtct
     1201 gaattgagtt acctggcaca taacctctgt gaaattgata agtaccgagt agagacatgc
     1261 tgtgtaattg gcaattatta cagcttacgc tcccagcatg agaaagcagc gttgtatttc
     1321 cagagagccc tgaaattgaa tcctaggtac cttggggcct ggacgctgat ggggcatgag
     1381 tacatggaaa tgaaaaacac atctgcggct attcaggctt accgacatgc cattgaggtc
     1441 aacaagagag actacagagc ttggtatggc cttgggcaga cctacgaaat ccttaagatg
     1501 ccattttatt gcctttatta ttatagacgg gcccaccagc ttcggcccaa cgattctcgt
     1561 atgctggttg ccttaggaga atgttatgag aaactcaatc aactagtgga agccaaaaag
     1621 tgttattgga gagcatacgc tgtgggagat gtggagaaaa tggctctggt gaagctggcc
     1681 aagcttcatg aacagttgac tgagtcagag caggctgccc agtgttacat caaatacatc
     1741 caagatatct attcctgtgg ggaaacagtg gagcacttag aggagagcac agccttccgc
     1801 tacctggccc agtactattt taaatgcaag ctgtgggatg aagcttcaac ttgtgcccaa
     1861 aaatgttgtg cattcaatga tacccgggaa gaaggtaagg ccttgctccg ccagatccta
     1921 cagctgagga accaagggga gacacccacc tctgacacgc ctggtacctt tttcctccct
     1981 gcctcactgt ctgcaaacaa cactcccaca cgcagagttt ctccactcaa cttgtcttca
     2041 gtcacaccat agttgactac tctcaagtca gaccaatatt aaaccttacc tccagtaaag
     2101 aacagccacg tctgttctcc caaggaccta agctcttctc ctttctatag acagaaacag
     2161 cctgagggac agcctatgga gccaccttca gaggcaggca gatacatggc aggggacaga
     2221 ctgtcttctg ccagccaaca actcttcctt ctattcagaa tggcaggtct tggccttcct
     2281 agtctctcca ctccctcaga agcgatgcca ctgaagcaag gtttcagtgc tgcgagttgg
     2341 gtgggcaagg aacagagcaa agttcatcat gcttgtcctc tgcaagcagg gaggttagct
     2401 ttgaacaatg acttttttta aagcagggtt tctctgtata gcctagcctg aagcttttct
     2461 gcctcagcct ccctaatgac aggattacag gaatatgcca cgaggcatgg ctagaagaat
     2521 acctttcttt tactgacagt cagagttctg atgccagaga ttaggtttaa attgagtgga
     2581 gctatctgtg atcttgtgga gagttttcaa aagaagctgc ctaaaaccct ccaagtgaga
     2641 gtctcagtga gcatgaactg gctcacatga ggggccagcg ggccacagct atataccaga
     2701 tgaaagcaac ccgaggagac aacttcatgg acatttttga aaggaacttt tttacttcag
     2761 atattaaagt ttatgctggt atcttttagt aaatgcttga tgtaaatttt ttttttttaa
     2821 atctccaaaa aggttttcaa ccttacctac aaggttgaag gagtcatcct tttttctagg
     2881 tttcagatac ccttgatgtc tgctataatg agctcgtgca gtaggtgcta tagaccattc
     2941 tgtgtttagg atctagcttt ccttctcttg taccagaaca tttatattct cctcttaatg
     3001 ggaggaatat cagctgggtg tggtacattg gtgcatgtct ttaatcccag catttcggag
     3061 acagaggcag gtggatgttt taacatagca actaccaggc cagacagagc taccctttgg
     3121 gtatctcata gcgttttact catttcctag catgcactag gctgggttcc cactgctgtt
     3181 cccgtccaag ggcccaacag gccagatggt atttatatca attttctgtc ccccttttat
     3241 atttttctaa atttggaatc caaataaaag cataaacaat g
//
