LOCUS       NM_001024744            2258 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus cell division cycle 16 (Cdc16), mRNA.
ACCESSION   NM_001024744 XM_214393
VERSION     NM_001024744.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2258)
  AUTHORS   Mansfeld J, Collin P, Collins MO, Choudhary JS and Pines J.
  TITLE     APC15 drives the turnover of MCC-CDC20 to make the spindle assembly
            checkpoint responsive to kinetochore attachment
  JOURNAL   Nat Cell Biol 13 (10), 1234-1243 (2011)
   PUBMED   21926987
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2258)
  AUTHORS   Jin L, Williamson A, Banerjee S, Philipp I and Rape M.
  TITLE     Mechanism of ubiquitin-chain formation by the human
            anaphase-promoting complex
  JOURNAL   Cell 133 (4), 653-665 (2008)
   PUBMED   18485873
REFERENCE   3  (bases 1 to 2258)
  AUTHORS   Dube P, Herzog F, Gieffers C, Sander B, Riedel D, Muller SA, Engel
            A, Peters JM and Stark H.
  TITLE     Localization of the coactivator Cdh1 and the cullin subunit Apc2 in
            a cryo-electron microscopy model of vertebrate APC/C
  JOURNAL   Mol Cell 20 (6), 867-879 (2005)
   PUBMED   16364912
REFERENCE   4  (bases 1 to 2258)
  AUTHORS   Fan M, Rhee J, St-Pierre J, Handschin C, Puigserver P, Lin J,
            Jaeger S, Erdjument-Bromage H, Tempst P and Spiegelman BM.
  TITLE     Suppression of mitochondrial respiration through recruitment of
            p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK
  JOURNAL   Genes Dev 18 (3), 278-289 (2004)
   PUBMED   14744933
REFERENCE   5  (bases 1 to 2258)
  AUTHORS   Tugendreich S, Tomkiel J, Earnshaw W and Hieter P.
  TITLE     CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic
            spindle and is essential for the metaphase to anaphase transition
  JOURNAL   Cell 81 (2), 261-268 (1995)
   PUBMED   7736578
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097498.1.
            
            On Jun 10, 2005 this sequence version replaced XM_214393.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097498.1, SRR8487231.41691.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2258
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.5"
     gene            1..2258
                     /gene="Cdc16"
                     /note="cell division cycle 16"
                     /db_xref="GeneID:290875"
                     /db_xref="RGD:1305076"
     exon            1..166
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..1981
                     /gene="Cdc16"
                     /note="cell division cycle 16 homolog"
                     /codon_start=1
                     /product="cell division cycle protein 16 homolog"
                     /protein_id="NP_001019915.1"
                     /db_xref="GeneID:290875"
                     /db_xref="RGD:1305076"
                     /translation="MNLEPLRKRVRQYLDQQQYQSALFWADKVASLSHEEPQDVYWLA
                     QCLYLTAQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEYQQALDILDMEEPINRR
                     LFEKYLKDDSGSKDPSSDWEMSQSSIKSSICLLRGKIYDALDNRTLATYSYKEALKLD
                     VYCFEAFDLLTSHHMLTAQEEKELLDSLPLSKLCAEEQELLRFVFENKLKKYNKPSET
                     VIPQSVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSAVMEKDPFHANCLPVHIGTLV
                     ELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATTLEKTYG
                     PAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFG
                     QALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLNN
                     LGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGL
                     RRDDTFSVTMLGHCIEMYIGDSEAYIGADIKDKLKCYDFDVHTMKTLKNIISPPWDFR
                     DFEVEKQNTEEAGLAPLENATKTPESRPSLEETFEIEMNESDMMLETSMSDHST"
     exon            167..221
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            222..319
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            320..358
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            359..499
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            500..659
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            660..751
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            752..885
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            886..965
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1015
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1016..1089
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1090..1215
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1368
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1432
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1433..1494
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1495..1630
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1631..1721
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1722..2228
                     /gene="Cdc16"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgccgtgtg gcgcgcgggg tctgatccgg gtggtggtcg gcgggcttgg gtccatcgac
       61 acccgggggc gcgcggaggc tcgagggggt gtcgggtgcc tgacctggcc tcgcggccat
      121 gaacctggag ccgctgcgca aacgcgtccg gcagtacctg gaccagcaac agtatcaaag
      181 tgctctgttt tgggcagaca aggtagcttc actctctcat gaggaacccc aggatgttta
      241 ttggttggct cagtgtcttt acctcacagc acagtaccac agagcagccc atgcactccg
      301 gtcacgcaag ctggacaaac tgtatgaagc ttgccgatac cttgcagcta gatgccacta
      361 tgctgcgaaa gagtaccagc aggctctaga catccttgat atggaggaac caattaacag
      421 aaggctcttt gagaagtacc tgaaggatga cagtggctcc aaagaccctt ccagtgactg
      481 ggagatgtca cagtcctcca taaagagctc gatttgtctt ctgaggggga aaatctacga
      541 tgcattagat aatcgcaccc tggctaccta cagttacaaa gaggctttga agctcgacgt
      601 ctactgcttt gaagcatttg atcttctgac gtcacaccac atgttgacag cacaggaaga
      661 aaaagaactt ctagactcac tgcctcttag caagctctgt gccgaagaac aagaattgct
      721 acgatttgta tttgagaaca aattaaagaa gtataataag cccagtgaga ctgtcattcc
      781 ccagtcagtg gacggcttgc aagagaatct ggatgtggta gtgtctttgg ctgagagaca
      841 ctattataac tgtgatttta agatgtgcta caagcttacg tctgcagtga tggaaaagga
      901 ccctttccat gcaaactgtt tacctgtgca cataggaact cttgtggagt tgaataaagc
      961 aaatgaactt ttctatcttt ctcacaaatt ggtggattta tatccgagta atcctgtgtc
     1021 gtggttcgcg gtgggctgct actacctcat ggttggccat aaaaacgagc acgccaggag
     1081 atacctcagc aaagctacca cactggagaa gacctatggg cccgcctgga tagcctacgg
     1141 gcactccttc gctgtggaga gcgagcatga ccaagccatg gctgcttatt tcacagccgc
     1201 acagctcatg aaggggtgtc acttgccaat gctgtatatt gggttagaat atggtttgac
     1261 caataactct aaactggctg agcggttctt tggccaagct ctgagcattg ccccggaaga
     1321 cccgtttgtc atccatgagg ttggagtggt tgcctttcag aatggagaat ggaaaacagc
     1381 agaaaagtgg tttctcgatg ctttggaaaa aattaaagca attgggaatg aggtaacagt
     1441 tgacaaatgg gaacctttat tgaacaacct ggggcatgtc tgcagaaaac tcaagaagta
     1501 cgccgaggct ctggattacc acaggcaggc actggtgctg atccctcaga atgcgtccac
     1561 atactctgct ataggctaca tccacagtct gatgggcaac ttcgaaaacg ctgtggacta
     1621 tttccataca gctctcggtc ttaggcgaga cgacacgttt tctgttacaa tgcttggtca
     1681 ttgcattgaa atgtacattg gagattccga agcttatatc ggagcagaca ttaaagacaa
     1741 actaaagtgc tatgactttg acgtgcatac aatgaaaaca ctaaaaaaca tcatttcgcc
     1801 tccgtgggat ttcagggact ttgaagtaga aaagcagaac acagaggaag ccgggcttgc
     1861 acctctggaa aacgccacta aaaccccgga gtccagacct tccttggaag agacttttga
     1921 aattgaaatg aacgaaagtg acatgatgct agagacatct atgtcagacc acagcacata
     1981 gccacagcac acaattgaca gaggtccagg gccaccctcg tgtgccagca taggtcagtg
     2041 ctccctcgcg gccttgctac atcttaagaa tttcccagtt cctgctgtga ctcctaacta
     2101 cagctctaca ttaaagacca gcagcctgcg ttaaatgtgg gacagcagac cctggccgca
     2161 gatgttctct gatcttctga gcctacagag tagtacatgt agcagaataa aggtcaatgt
     2221 tcattgtcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
