LOCUS       NM_001399575            2234 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus cytidine and dCMP deaminase domain containing 1
            (Cdadc1), transcript variant 2, mRNA.
ACCESSION   NM_001399575 XM_006252123
VERSION     NM_001399575.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2234)
  AUTHORS   Xu,Y., Li,L., Li,J. and Liu,Q.
  TITLE     Structural and biological function of NYD-SP15 as a new member of
            cytidine deaminases
  JOURNAL   Gene 583 (1), 36-47 (2016)
   PUBMED   26945630
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Jan 12, 2022 this sequence version replaced XM_006252123.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ213068.1, SRR26360176.234743.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760434 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-192               JAXUCZ010000015.1  37931593-37931784   c
            193-290             JAXUCZ010000015.1  37930634-37930731   c
            291-365             JAXUCZ010000015.1  37926810-37926884   c
            366-543             JAXUCZ010000015.1  37924125-37924302   c
            544-1113            JAXUCZ010000015.1  37920190-37920759   c
            1114-1163           JAXUCZ010000015.1  37915717-37915766   c
            1164-1333           JAXUCZ010000015.1  37913276-37913445   c
            1334-1523           JAXUCZ010000015.1  37911026-37911215   c
            1524-1584           JAXUCZ010000015.1  37907604-37907664   c
            1585-2234           JAXUCZ010000015.1  37902789-37903438   c
FEATURES             Location/Qualifiers
     source          1..2234
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p12"
     gene            1..2234
                     /gene="Cdadc1"
                     /note="cytidine and dCMP deaminase domain containing 1"
                     /db_xref="GeneID:361052"
                     /db_xref="RGD:1311845"
     exon            1..192
                     /gene="Cdadc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             111..1682
                     /gene="Cdadc1"
                     /EC_number="3.5.4.5"
                     /note="isoform 2 is encoded by transcript variant 2;
                     cytidine and dCMP deaminase domain-containing protein 1"
                     /codon_start=1
                     /product="cytidine and dCMP deaminase domain-containing
                     protein 1 isoform 2"
                     /protein_id="NP_001386504.1"
                     /db_xref="GeneID:361052"
                     /db_xref="RGD:1311845"
                     /translation="MKETDPMQSLEGSGAERSVGTQTGSMTGQIPRLSKVNLFTLLSL
                     WMELFPGVEAQGQKSQKTEEETRGPLGDNEDLARVSTDKKQVKKTGLVVVKNMKIIGL
                     HCSSEDLHTGQIALIKHGSRLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPSDPEIS
                     LLTEASSSEDAKLDAKAAERLKSNSRAHVCVLLQPLVCYMVQFVEETSYKCDFIQKTA
                     KALPGADTDFYSECKQERIKEYEMLFLVSNEEMHKQILMTIGLENLCENPYFSNLRQN
                     MKDLILLLATVASSVPNLKHFGFYCSNPEQINEIHNQSLPQEVARHCMVQARLLAYRT
                     EDHKTGVGAVIWAEAKSRSCDGTGAMYFVGCGYNAFPVGSEYADFPHMDDKHKDREIR
                     KFRYIIHAEQNALTFRCQDIKPEERSMIFVTKCPCDECVPLIKGAGIKQIYAGDVDVG
                     KKKADISYMKFGELEGVHKFTWQLNPSEAYSLDPDEPERRENGVLRRRSAKEEQRSNK
                     RPRLETRSAGRATLQ"
     exon            193..290
                     /gene="Cdadc1"
                     /inference="alignment:Splign:2.1.0"
     exon            291..365
                     /gene="Cdadc1"
                     /inference="alignment:Splign:2.1.0"
     exon            366..543
                     /gene="Cdadc1"
                     /inference="alignment:Splign:2.1.0"
     exon            544..1113
                     /gene="Cdadc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1163
                     /gene="Cdadc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1164..1333
                     /gene="Cdadc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1334..1523
                     /gene="Cdadc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1524..1584
                     /gene="Cdadc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1585..2234
                     /gene="Cdadc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcaaaacgag cggttgttga caggccgcag aggcggctga aggtgagctg agtgtatcct
       61 atcatgcctg actgggcgag ttgtcctggg ccgaggcctc tgggctgggg atgaaagaaa
      121 cggatccgat gcagagtctg gagggctccg gggccgagag gtcagtcggc acgcagacgg
      181 gcagcatgac gggtcaaata ccaaggcttt ctaaagtgaa cctttttact ctgctcagtc
      241 tctggatgga gctcttcccg ggagtagaag cccaagggca aaaatctcag aaaactgaag
      301 aggaaacccg tggtccctta ggagataatg aagacctggc cagagtatct actgacaaaa
      361 aacaggttaa gaaaactggt cttgtggtgg taaaaaacat gaagatcatt ggtctgcact
      421 gttccagtga agacttgcat actgggcaaa ttgctcttat taagcatggg tccaggctga
      481 aaaactgtga tctttatttt tcaagaaaac cgtgttctgc ttgtttgaaa atgatagtga
      541 atgctggagt taaccgaatt tcttactggc cttctgaccc agaaataagt ttgctcactg
      601 aggcttctag ttctgaagat gcaaagctag atgccaaagc agcagaacga ttgaagtcaa
      661 acagccgggc ccacgtgtgc gtcctcctcc agccgctggt gtgttacatg gtgcagtttg
      721 tagaggaaac ttcttacaaa tgtgacttta ttcaaaaaac tgcaaaagca ttgccgggtg
      781 ctgacactga tttttattct gaatgtaaac aagaaagaat aaaagaatat gaaatgttat
      841 ttttggtttc aaatgaagag atgcataagc agatactgat gactataggt ctggagaacc
      901 tgtgtgaaaa cccctatttt agcaatctaa ggcaaaacat gaaagacctg atcctacttt
      961 tggccacagt agcttccagt gtgcccaact tgaaacactt cggattctac tgtagcaacc
     1021 cagaacagat taatgaaatt cacaatcaga gtttgccaca ggaagttgca aggcattgca
     1081 tggtgcaggc caggttattg gcttatcgaa ctgaggatca taaaacagga gtcggagctg
     1141 tcatttgggc agaagcgaaa tctagaagct gcgatggaac tggagctatg tacttcgtag
     1201 gatgcgggta caatgccttt cccgttggct ccgagtatgc tgacttcccg cacatggatg
     1261 acaagcataa ggacagagaa atacggaagt tcagatacat catacatgcg gagcagaatg
     1321 ctttgacatt tagatgtcaa gatataaaac cggaagaacg cagcatgatt tttgtgacga
     1381 aatgcccttg tgatgaatgt gtacctttaa tcaagggtgc aggcataaag cagatctatg
     1441 ctggcgatgt agacgttggg aagaagaaag cagacatctc ctacatgaag tttggggagc
     1501 ttgagggcgt ccacaaattc acatggcagt tgaatccgtc tgaagcttat agtcttgacc
     1561 cagatgagcc tgaaaggaga gaaaatggtg tactgaggcg caggtctgca aaggaagagc
     1621 agcgcagcaa caagaggcca cgtctggaaa cccgctctgc aggccgggct acactgcagt
     1681 aacccacatg ctttcttact gcacctctca aatgcagcct gtggggttgt gactaactga
     1741 gaagctttta cagggctgag ttgtaattag cctctgagtg ctgttacctt ggatcttttt
     1801 acctcagcat gcagtgtgtt cttccactac actaaatggg gtagcaatag tttgagacca
     1861 gtacaagacc tgggccgctg ctctgaaggc agtttcagaa cggttcattc ataggagggg
     1921 atcttccttt gacaaatagt agttactgtg gattacaagg atgacaatca gaaccctcca
     1981 ggcaataaga tgcctggccg tcttttaagg ctccatgtat aaataactga aaggctgcat
     2041 aacactaagt ccttctagcc aggacctgct gaaatagact gacttaaaat tgctgtgcct
     2101 actctccatt tcacacgagt tttgtaagta gcctggggat ttaggtcagt ggagctgtgc
     2161 tgtgagagca tgtgccaagc cctgagttcc ctccttagca cctcaaaaca aataaaatgt
     2221 taatctcacc taaa
//
