LOCUS       NM_031797               1838 bp    mRNA    linear   ROD 24-APR-2024
DEFINITION  Rattus norvegicus Cd82 molecule (Cd82), transcript variant 1, mRNA.
ACCESSION   NM_031797
VERSION     NM_031797.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1838)
  AUTHORS   Shah,J., Rouaud,F., Guerrera,D., Vasileva,E., Popov,L.M.,
            Kelley,W.L., Rubinstein,E., Carette,J.E., Amieva,M.R. and Citi,S.
  TITLE     A Dock-and-Lock Mechanism Clusters ADAM10 at Cell-Cell Junctions to
            Promote alpha-Toxin Cytotoxicity
  JOURNAL   Cell Rep 25 (8), 2132-2147 (2018)
   PUBMED   30463011
REFERENCE   2  (bases 1 to 1838)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   3  (bases 1 to 1838)
  AUTHORS   Mela,A. and Goldman,J.E.
  TITLE     The tetraspanin KAI1/CD82 is expressed by late-lineage
            oligodendrocyte precursors and may function to restrict precursor
            migration and promote oligodendrocyte differentiation and
            myelination
  JOURNAL   J Neurosci 29 (36), 11172-11181 (2009)
   PUBMED   19741124
  REMARK    GeneRIF: CD82 appears to be a critical molecule in the regulation
            of oligodendrocyte progenitor migration and myelination.
REFERENCE   4  (bases 1 to 1838)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   5  (bases 1 to 1838)
  AUTHORS   Ai,X., Zhang,X., Wu,Z., Ma,X., Ju,Z., Wang,B. and Shi,T.
  TITLE     Expression of KAI1/CD82 and MRP-1/CD9 in transitional cell
            carcinoma of bladder
  JOURNAL   J Huazhong Univ Sci Technolog Med Sci 27 (1), 79-82 (2007)
   PUBMED   17393117
REFERENCE   6  (bases 1 to 1838)
  AUTHORS   Szpirer,C., Van Vooren,P., Riviere,M., Scohy,S., Collau,G. and
            Szpirer,J.
  TITLE     Localization of 54 rat genes, and definition of new synteny groups
            conserved in the human and the rat
  JOURNAL   Mamm Genome 11 (9), 729-735 (2000)
   PUBMED   10967130
REFERENCE   7  (bases 1 to 1838)
  AUTHORS   Geradts,J., Maynard,R., Birrer,M.J., Hendricks,D., Abbondanzo,S.L.,
            Fong,K.M., Barrett,J.C. and Lombardi,D.P.
  TITLE     Frequent loss of KAI1 expression in squamous and lymphoid
            neoplasms. An immunohistochemical study of archival tissues
  JOURNAL   Am J Pathol 154 (6), 1665-1671 (1999)
   PUBMED   10362791
REFERENCE   8  (bases 1 to 1838)
  AUTHORS   Suzuki,H., Dong,J.T., Gao,A.C., Barrett,J.C. and Isaacs,J.T.
  TITLE     Identification of the rat homologue of KAI1 and its expression in
            Dunning rat prostate cancers
  JOURNAL   Prostate 37 (4), 253-260 (1998)
   PUBMED   9831222
REFERENCE   9  (bases 1 to 1838)
  AUTHORS   Zhao,X.S., Li,X.B., Zhu,Y.C., Wan,D.F. and Yao,T.
  TITLE     Identification of upregulated genes in the thymus of spontaneously
            hypertensive rats by cDNA representational difference analysis
  JOURNAL   Blood Press 7 (5-6), 316-323 (1998)
   PUBMED   10321446
REFERENCE   10 (bases 1 to 1838)
  AUTHORS   Kawana,Y., Komiya,A., Ueda,T., Nihei,N., Kuramochi,H., Suzuki,H.,
            Yatani,R., Imai,T., Dong,J.T., Imai,T., Yoshie,O., Barrett,J.C.,
            Isaacs,J.T., Shimazaki,J., Ito,H. and Ichikawa,T.
  TITLE     Location of KAI1 on the short arm of human chromosome 11 and
            frequency of allelic loss in advanced human prostate cancer
  JOURNAL   Prostate 32 (3), 205-213 (1997)
   PUBMED   9254900
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC072498.1.
            
            On Dec 11, 2007 this sequence version replaced NM_031797.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC072498.1, AF049882.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMN06680453
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1838
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q31"
     gene            1..1838
                     /gene="Cd82"
                     /gene_synonym="Kai1"
                     /note="Cd82 molecule"
                     /db_xref="GeneID:83628"
                     /db_xref="RGD:69070"
     exon            1..156
                     /gene="Cd82"
                     /gene_synonym="Kai1"
                     /inference="alignment:Splign:2.1.0"
     exon            157..232
                     /gene="Cd82"
                     /gene_synonym="Kai1"
                     /inference="alignment:Splign:2.1.0"
     exon            233..315
                     /gene="Cd82"
                     /gene_synonym="Kai1"
                     /inference="alignment:Splign:2.1.0"
     CDS             253..1053
                     /gene="Cd82"
                     /gene_synonym="Kai1"
                     /note="Kangai 1 (suppression of tumorigenicity 6,
                     prostate; CD82 antigen (R2 leukocyte antigen, antigen
                     detected by monoclonal and antibody IA4)); kangai 1
                     (suppression of tumorigenicity 6), prostate; metastasis
                     suppressor Kangai-1 homolog; Kangai 1 (suppression of
                     tumerigenicity 6 prostate) CD82 antigen"
                     /codon_start=1
                     /product="CD82 antigen"
                     /protein_id="NP_113985.2"
                     /db_xref="GeneID:83628"
                     /db_xref="RGD:69070"
                     /translation="MGAGCVKVTKYFLFLFNLLFFILGAVILGFGVWILADKSSFISV
                     LQTSSSSLQVGAYVFIGVGAITMLMGFLGCIGAVNEVRCLLGLYFVFLLLILIAQVTV
                     GVLFYFNADKLKQEMGNTVMDIIQNYSVNASSSREEAWDYVQAQVKCCGWVSPSNWTR
                     NPVLKNSTKTTYPCSCEKTKEEDNQLIVKKGFCESDNSTASENSPEDWPVHPEGCMEK
                     AQAWLQENFGILLGVCAGVAVIELLGLFLSICLCRYIHSEDYSKVPKY"
     exon            316..388
                     /gene="Cd82"
                     /gene_synonym="Kai1"
                     /inference="alignment:Splign:2.1.0"
     exon            389..513
                     /gene="Cd82"
                     /gene_synonym="Kai1"
                     /inference="alignment:Splign:2.1.0"
     exon            514..588
                     /gene="Cd82"
                     /gene_synonym="Kai1"
                     /inference="alignment:Splign:2.1.0"
     exon            589..690
                     /gene="Cd82"
                     /gene_synonym="Kai1"
                     /inference="alignment:Splign:2.1.0"
     exon            691..891
                     /gene="Cd82"
                     /gene_synonym="Kai1"
                     /inference="alignment:Splign:2.1.0"
     exon            892..975
                     /gene="Cd82"
                     /gene_synonym="Kai1"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1815
                     /gene="Cd82"
                     /gene_synonym="Kai1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgtggcctga caaggccgtt gagcttctgg actgacttcg ggagggggtt gccggggaga
       61 gcaaagggac agagccaagc tgcgcagtca aacacgggtt ggggcggcag ctgaagacgc
      121 caacttaaaa gcgcgtagcc agaacccagg cagcagtgtg tccattgtcc agaactcatc
      181 tgagaaactg ccacaggaag tgctgctctg ctccagtctg gtcactgaaa agggagctcc
      241 aggacctgca ggatgggggc aggctgtgtc aaagtcacca agtacttcct cttcctcttc
      301 aatctgctgt tctttatcct gggtgctgtg atcctgggct ttggggtgtg gattcttgca
      361 gacaagagca gcttcatttc tgtcctacaa acctcatcca gctcgctgca ggtgggggca
      421 tacgtcttca ttggtgtggg cgccatcacc atgctgatgg gcttcctggg ctgtattggt
      481 gctgtcaatg aggtccgctg cctgctgggt ctgtacttcg tcttccttct gctgattctt
      541 atagcacagg tgactgtagg ggtcctcttc tacttcaatg ctgacaagct gaagcaggag
      601 atggggaaca cagtgatgga cattattcag aactacagcg tcaatgccag cagcagccgc
      661 gaggaggctt gggactatgt gcaggcgcag gtgaagtgct gtggctgggt cagcccctcc
      721 aactggacac gtaacccggt gctcaagaac tctaccaaga ccacttaccc atgctcctgt
      781 gagaagacga aggaggagga caaccagctc attgtgaaga aagggttctg tgagtctgac
      841 aacagcaccg caagtgaaaa cagtcctgag gactggcctg tgcacccgga ggggtgcatg
      901 gagaaggctc aggcgtggct acaggagaac ttcggcatcc ttctgggcgt gtgtgctggt
      961 gttgctgtca ttgagctgct ggggttgttc ctgtccatat gtttgtgccg gtacattcat
     1021 tctgaagatt acagcaaggt ccccaagtac tgaggctgct gatgtcccca ctgtcctgtg
     1081 tttctccacc ctcagtctcc cacagggcct ctagagcttt cccacatgag ccgtgctcca
     1141 tctactactg aggcctctgg cccaccctgg gaaggttgta ggaactttct gggcctgggc
     1201 ccttctccct gcctttctgc caccaatatg gggcccttac tgtcctgtag ctcttcctcc
     1261 tactgcctgg aatattttta acagcttgaa atggctccca gtattactgt acacaggata
     1321 gctgggtccc caccctgaag tcatattata acaatataat attaaaaacc agggagggtg
     1381 ggctagcacc catggctgcc cagggaaagg ccacaggaaa ggttagtggt ttccccactg
     1441 tgacactttc tttatgggtt ttcaatgttt ctgtgggaga cagggtaggc agttcttgta
     1501 cacacttgga atactccccc caagctcagt tcagcaggga actgaacgga gaggctgcct
     1561 gggggactgg cccaggtagc ccccagtgag cttttccttg gtgagggacc tgacagctta
     1621 ggggcatggg tccctcaggt ctggcataag accctgagtt gtctggacaa gagaaggagg
     1681 atctggactg gtatttcttg gcagctgtcc cctgtcccct gggctaaggg tgggtgaggc
     1741 tgtgccttgc agggtggggg agggtttcca tatgctcatc tctgaaatca actattaaag
     1801 gaggatttgt aacaaaaaaa aaaaaaaaaa aaaaaaaa
//
