LOCUS       NM_133533               1235 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus CD79b molecule (Cd79b), mRNA.
ACCESSION   NM_133533
VERSION     NM_133533.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1235)
  AUTHORS   Chen,Z., Zou,Y., Liu,W., Guan,P., Tao,Q., Xiang,C., Zhang,W.,
            Ye,Y., Yan,J. and Zhao,S.
  TITLE     Morphologic Patterns and the Correlation With MYD88 L265P, CD79B
            Mutations in Primary Adrenal Diffuse Large B-Cell Lymphoma
  JOURNAL   Am J Surg Pathol 44 (4), 444-455 (2020)
   PUBMED   31609782
REFERENCE   2  (bases 1 to 1235)
  AUTHORS   Cao,X.X., Li,J., Cai,H., Zhang,W., Duan,M.H. and Zhou,D.B.
  TITLE     Patients with primary breast and primary female genital tract
            diffuse large B cell lymphoma have a high frequency of MYD88 and
            CD79B mutations
  JOURNAL   Ann Hematol 96 (11), 1867-1871 (2017)
   PUBMED   28803429
REFERENCE   3  (bases 1 to 1235)
  AUTHORS   Grommes,C., Pastore,A., Palaskas,N., Tang,S.S., Campos,C.,
            Schartz,D., Codega,P., Nichol,D., Clark,O., Hsieh,W.Y., Rohle,D.,
            Rosenblum,M., Viale,A., Tabar,V.S., Brennan,C.W., Gavrilovic,I.T.,
            Kaley,T.J., Nolan,C.P., Omuro,A., Pentsova,E., Thomas,A.A.,
            Tsyvkin,E., Noy,A., Palomba,M.L., Hamlin,P., Sauter,C.S.,
            Moskowitz,C.H., Wolfe,J., Dogan,A., Won,M., Glass,J., Peak,S.,
            Lallana,E.C., Hatzoglou,V., Reiner,A.S., Gutin,P.H., Huse,J.T.,
            Panageas,K.S., Graeber,T.G., Schultz,N., DeAngelis,L.M. and
            Mellinghoff,I.K.
  TITLE     Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in
            Primary CNS Lymphoma
  JOURNAL   Cancer Discov 7 (9), 1018-1029 (2017)
   PUBMED   28619981
REFERENCE   4  (bases 1 to 1235)
  AUTHORS   Pfeifer,M., Zheng,B., Erdmann,T., Koeppen,H., McCord,R., Grau,M.,
            Staiger,A., Chai,A., Sandmann,T., Madle,H., Dorken,B., Chu,Y.W.,
            Chen,A.I., Lebovic,D., Salles,G.A., Czuczman,M.S.,
            Palanca-Wessels,M.C., Press,O.W., Advani,R., Morschhauser,F.,
            Cheson,B.D., Lenz,P., Ott,G., Polson,A.G., Mundt,K.E. and Lenz,G.
  TITLE     Anti-CD22 and anti-CD79B antibody drug conjugates are active in
            different molecular diffuse large B-cell lymphoma subtypes
  JOURNAL   Leukemia 29 (7), 1578-1586 (2015)
   PUBMED   25708834
REFERENCE   5  (bases 1 to 1235)
  AUTHORS   Yamada,S., Ishida,Y., Matsuno,A. and Yamazaki,K.
  TITLE     Primary diffuse large B-cell lymphomas of central nervous system
            exhibit remarkably high prevalence of oncogenic MYD88 and CD79B
            mutations
  JOURNAL   Leuk Lymphoma 56 (7), 2141-2145 (2015)
   PUBMED   25347427
REFERENCE   6  (bases 1 to 1235)
  AUTHORS   Alfarano,A., Indraccolo,S., Circosta,P., Minuzzo,S., Vallario,A.,
            Zamarchi,R., Fregonese,A., Calderazzo,F., Faldella,A., Aragno,M.,
            Camaschella,C., Amadori,A. and Caligaris-Cappio,F.
  TITLE     An alternatively spliced form of CD79b gene may account for altered
            B-cell receptor expression in B-chronic lymphocytic leukemia
  JOURNAL   Blood 93 (7), 2327-2335 (1999)
   PUBMED   10090943
REFERENCE   7  (bases 1 to 1235)
  AUTHORS   Nakazato,S., Nomoto,K., Kazahari,K. and Ono,M.
  TITLE     Physical linkage of the B29/Ig-beta (CD79B) gene to the skeletal
            muscle, sodium-channel, and growth hormone genes in rat and human
  JOURNAL   Genomics 48 (3), 363-368 (1998)
   PUBMED   9545642
REFERENCE   8  (bases 1 to 1235)
  AUTHORS   Thompson,A.A., Talley,J.A., Do,H.N., Kagan,H.L., Kunkel,L.,
            Berenson,J., Cooper,M.D., Saxon,A. and Wall,R.
  TITLE     Aberrations of the B-cell receptor B29 (CD79b) gene in chronic
            lymphocytic leukemia
  JOURNAL   Blood 90 (4), 1387-1394 (1997)
   PUBMED   9269755
REFERENCE   9  (bases 1 to 1235)
  AUTHORS   Richards,J.D., Gold,M.R., Hourihane,S.L., DeFranco,A.L. and
            Matsuuchi,L.
  TITLE     Reconstitution of B cell antigen receptor-induced signaling events
            in a nonlymphoid cell line by expressing the Syk protein-tyrosine
            kinase
  JOURNAL   J Biol Chem 271 (11), 6458-6466 (1996)
   PUBMED   8626447
REFERENCE   10 (bases 1 to 1235)
  AUTHORS   Matsuuchi,L., Gold,M.R., Travis,A., Grosschedl,R., DeFranco,A.L.
            and Kelly,R.B.
  TITLE     The membrane IgM-associated proteins MB-1 and Ig-beta are
            sufficient to promote surface expression of a partially functional
            B-cell antigen receptor in a nonlymphoid cell line
  JOURNAL   Proc Natl Acad Sci U S A 89 (8), 3404-3408 (1992)
   PUBMED   1373499
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088115.1.
            
            On Jan 12, 2005 this sequence version replaced NM_133533.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088115.1, FQ226266.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1235
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..1235
                     /gene="Cd79b"
                     /gene_synonym="B29; Igb"
                     /note="CD79b molecule"
                     /db_xref="GeneID:171055"
                     /db_xref="RGD:620012"
     exon            1..125
                     /gene="Cd79b"
                     /gene_synonym="B29; Igb"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..745
                     /gene="Cd79b"
                     /gene_synonym="B29; Igb"
                     /note="B-cell antigen receptor complex-associated protein
                     beta chain; immunoglobulin-associated beta; CD79B antigen;
                     Cd79b molecule, immunoglobulin-associated beta"
                     /codon_start=1
                     /product="B-cell antigen receptor complex-associated
                     protein beta chain precursor"
                     /protein_id="NP_598217.1"
                     /db_xref="GeneID:171055"
                     /db_xref="RGD:620012"
                     /translation="MATLVLSPVPCHWLMFLLLLLSGEPVPAMTKSDQPPIFQGSPCS
                     KIWQHPRFAAKKRSSMVKFHCHTDYSGVMTWFRQKGNQRPQELFPEDGHISQTRNGSV
                     YTLTLQNIQYEDNGIYFCQQKCNSTEPDVTDGCGTELLVLGFSTLDQLKRRNTLKDGI
                     IMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLNIDQTATYEDIVTLRTGEVK
                     WSVGEHPGQE"
     exon            126..176
                     /gene="Cd79b"
                     /gene_synonym="B29; Igb"
                     /inference="alignment:Splign:2.1.0"
     exon            177..485
                     /gene="Cd79b"
                     /gene_synonym="B29; Igb"
                     /inference="alignment:Splign:2.1.0"
     exon            486..604
                     /gene="Cd79b"
                     /gene_synonym="B29; Igb"
                     /inference="alignment:Splign:2.1.0"
     exon            605..646
                     /gene="Cd79b"
                     /gene_synonym="B29; Igb"
                     /inference="alignment:Splign:2.1.0"
     exon            647..1211
                     /gene="Cd79b"
                     /gene_synonym="B29; Igb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacacagtta catgttttgc cccagaccct ccttgggctc agagacagag cagtgaccat
       61 ggccacactg gtgctgtctc ctgtgccctg ccactggctg atgttcctgc tgctgctcct
      121 ctcaggtgag ccagtaccag cgatgacaaa gagtgaccag ccaccgattt tccaaggaag
      181 cccttgttcc aagatctggc agcacccgag gtttgcagcc aaaaagcgga gctccatggt
      241 gaagtttcac tgccacacag actactcagg tgtcatgacc tggttccggc agaaagggaa
      301 ccagaggcct caggaactgt tcccagaaga cggacacatt tcgcagaccc ggaatggctc
      361 tgtctacacc ctcactctcc aaaacatcca gtatgaggat aacggcatct acttctgcca
      421 gcagaagtgc aacagcaccg aacctgatgt taccgatggc tgtggcacgg aacttctagt
      481 cttaggattc agcacgttgg accaactgaa gcggcggaac acgctgaaag atggcattat
      541 catgatccag accctcctca tcatcctctt catcatcgtc cccatcttct tactactaga
      601 caaggatgac agcaaggccg ggatggaaga ggaccacacc tatgagggct tgaacattga
      661 ccagacagcc acctatgaag acatagtgac tcttcggaca ggggaggtaa agtggtctgt
      721 gggagagcac ccaggccagg agtgagggcc acctccatcc tgctcaactc ttgggcctca
      781 ctgtttccaa actgcctggc tcacagtctg ttccctgctt cctggatacc ctggccagca
      841 tctgaagttg gaccatcaat gtcacctctc tttctagcct ctggtcccca gctcttgctg
      901 aagggcccgg ggtagaagga caatagggtg gtggcatgga gtaaggagtt ctctggggga
      961 tagacttgac ccaaggcttc tggaaatgct atgcagtttc tgtccccatg tttgggacag
     1021 gaaagcagag acttgttgga atctgcaaat ggactcagca cattggcttc ctgaggagtc
     1081 cgggaaggac cacggttcac agtggcacct agaagggaat gccagaatgc cacttctccc
     1141 tctcatccca gggatcccct aaagcctata gcccatcctc ctgtggaata aacagcgtat
     1201 ctgacaccag aaaaaaaaaa aaaaaaaaaa aaaaa
//
