LOCUS       NM_134327               1604 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus Cd69 molecule (Cd69), mRNA.
ACCESSION   NM_134327 XM_232418
VERSION     NM_134327.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1604)
  AUTHORS   Motomura,Y., Kitamura,H., Hijikata,A., Matsunaga,Y., Matsumoto,K.,
            Inoue,H., Atarashi,K., Hori,S., Watarai,H., Zhu,J., Taniguchi,M.
            and Kubo,M.
  TITLE     The transcription factor E4BP4 regulates the production of IL-10
            and IL-13 in CD4+ T cells
  JOURNAL   Nat Immunol 12 (5), 450-459 (2011)
   PUBMED   21460847
REFERENCE   2  (bases 1 to 1604)
  AUTHORS   Gimferrer,I., Hu,T., Simmons,A., Wang,C., Souabni,A.,
            Busslinger,M., Bender,T.P., Hernandez-Hoyos,G. and Alberola-Ila,J.
  TITLE     Regulation of GATA-3 expression during CD4 lineage differentiation
  JOURNAL   J Immunol 186 (7), 3892-3898 (2011)
   PUBMED   21357543
REFERENCE   3  (bases 1 to 1604)
  AUTHORS   Flornes,L.M., Nylenna,O., Saether,P.C., Daws,M.R., Dissen,E. and
            Fossum,S.
  TITLE     The complete inventory of receptors encoded by the rat natural
            killer cell gene complex
  JOURNAL   Immunogenetics 62 (8), 521-530 (2010)
   PUBMED   20544345
REFERENCE   4  (bases 1 to 1604)
  AUTHORS   Terauchi,M., Li,J.Y., Bedi,B., Baek,K.H., Tawfeek,H., Galley,S.,
            Gilbert,L., Nanes,M.S., Zayzafoon,M., Guldberg,R., Lamar,D.L.,
            Singer,M.A., Lane,T.F., Kronenberg,H.M., Weitzmann,M.N. and
            Pacifici,R.
  TITLE     T lymphocytes amplify the anabolic activity of parathyroid hormone
            through Wnt10b signaling
  JOURNAL   Cell Metab 10 (3), 229-240 (2009)
   PUBMED   19723499
REFERENCE   5  (bases 1 to 1604)
  AUTHORS   Stone,E.L., Ismail,M.N., Lee,S.H., Luu,Y., Ramirez,K., Haslam,S.M.,
            Ho,S.B., Dell,A., Fukuda,M. and Marth,J.D.
  TITLE     Glycosyltransferase function in core 2-type protein O glycosylation
  JOURNAL   Mol Cell Biol 29 (13), 3770-3782 (2009)
   PUBMED   19349303
REFERENCE   6  (bases 1 to 1604)
  AUTHORS   Natarajan,K., Sawicki,M.W., Margulies,D.H. and Mariuzza,R.A.
  TITLE     Crystal structure of human CD69: a C-type lectin-like activation
            marker of hematopoietic cells
  JOURNAL   Biochemistry 39 (48), 14779-14786 (2000)
   PUBMED   11101293
REFERENCE   7  (bases 1 to 1604)
  AUTHORS   Sancho,D., Santis,A.G., Alonso-Lebrero,J.L., Viedma,F., Tejedor,R.
            and Sanchez-Madrid,F.
  TITLE     Functional analysis of ligand-binding and signal transduction
            domains of CD69 and CD23 C-type lectin leukocyte receptors
  JOURNAL   J Immunol 165 (7), 3868-3875 (2000)
   PUBMED   11034393
REFERENCE   8  (bases 1 to 1604)
  AUTHORS   Furuya,T., Salstrom,J.L., McCall-Vining,S., Cannon,G.W., Joe,B.,
            Remmers,E.F., Griffiths,M.M. and Wilder,R.L.
  TITLE     Genetic dissection of a rat model for rheumatoid arthritis:
            significant gender influences on autosomal modifier loci
  JOURNAL   Hum Mol Genet 9 (15), 2241-2250 (2000)
   PUBMED   11001927
REFERENCE   9  (bases 1 to 1604)
  AUTHORS   Simpson,S.J., Mizoguchi,E., Allen,D., Bhan,A.K. and Terhorst,C.
  TITLE     Evidence that CD4+, but not CD8+ T cells are responsible for murine
            interleukin-2-deficient colitis
  JOURNAL   Eur J Immunol 25 (9), 2618-2625 (1995)
   PUBMED   7589135
REFERENCE   10 (bases 1 to 1604)
  AUTHORS   Negishi,I., Motoyama,N., Nakayama,K., Nakayama,K., Senju,S.,
            Hatakeyama,S., Zhang,Q., Chan,A.C. and Loh,D.Y.
  TITLE     Essential role for ZAP-70 in both positive and negative selection
            of thymocytes
  JOURNAL   Nature 376 (6539), 435-438 (1995)
   PUBMED   7630421
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Nov 27, 2020 this sequence version replaced NM_134327.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088219.1, SRR26643292.20247.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760434 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               JAXUCZ010000004.1  164419276-164419403 c
            129-251             JAXUCZ010000004.1  164415364-164415486 c
            252-451             JAXUCZ010000004.1  164414156-164414355 c
            452-555             JAXUCZ010000004.1  164413757-164413860 c
            556-1604            JAXUCZ010000004.1  164411485-164412533 c
FEATURES             Location/Qualifiers
     source          1..1604
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1604
                     /gene="Cd69"
                     /note="Cd69 molecule"
                     /db_xref="GeneID:29187"
                     /db_xref="RGD:61318"
     exon            1..128
                     /gene="Cd69"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..664
                     /gene="Cd69"
                     /note="CD69 antigen; early activation antigen CD69"
                     /codon_start=1
                     /product="C-type lectin domain family 2 member A"
                     /protein_id="NP_599154.1"
                     /db_xref="GeneID:29187"
                     /db_xref="RGD:61318"
                     /translation="MNSEECSITENSSSHLERGQRDHGTSVHFEKHREGSIQVPIPCA
                     VLVVVLITSLIIALFALSVGKYNCPGFYENLESFDHHAASCKNEWFSYNGKCYFFSTT
                     TKTWALAQKSCSEDDATLAVIDSEKDMAFLKRYAGGLKHWIGLRNEASQTWKWANGKE
                     FNSWFNVTGSKKCVSLNHTDVASVDCEANLHWICSKASL"
     exon            129..251
                     /gene="Cd69"
                     /inference="alignment:Splign:2.1.0"
     exon            252..451
                     /gene="Cd69"
                     /inference="alignment:Splign:2.1.0"
     exon            452..555
                     /gene="Cd69"
                     /inference="alignment:Splign:2.1.0"
     exon            556..1604
                     /gene="Cd69"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctagggcaca ccatagacca cttgagattc accggggatc ttaagggaga aattttttta
       61 aaggatgaat tctgaagagt gttccataac agaaaatagc tcttcacatc tggagagagg
      121 gcagagggac catggcacca gtgtacattt tgagaagcat cgtgaaggat ccattcaagt
      181 tcctatccct tgtgctgtgc tcgtagtggt cctcatcact tccttaatta tcgctctctt
      241 tgccttaagt gtgggcaagt acaattgtcc gggcttctat gagaatctgg agtcatttga
      301 ccaccatgct gcttcctgca agaatgagtg gttttcatac aacgggaaat gttacttttt
      361 ctccaccaca accaagactt gggccttggc ccaaaaatct tgttctgaag atgacgctac
      421 ccttgctgtt attgattcgg aaaaggacat ggcgtttctg aagcgatatg ctggtggact
      481 gaaacactgg attgggctga gaaacgaagc tagtcagaca tggaaatggg caaatggcaa
      541 agaatttaac agctggttca acgtgacagg gtctaaaaag tgcgtgtctc tgaaccacac
      601 agatgttgct tctgtagact gcgaggcaaa cttacactgg atctgcagca aggcctccct
      661 atgaggagga agcatagagg tataggtgac tgtgccatag cacctcagga aagttgtgtg
      721 actggatgct actctgtgat tgagttttcc acaaagacca cacaaaccaa ctttacatca
      781 tcctggaact cttccagata gataggacta tggaacacaa ggaagaagac ccaggaaggt
      841 cccttgacca ggaactaaaa atgtcactga ctgactggaa atcacatcaa agatgagaag
      901 atggctatga agcctcataa atgcacttta tattttaaac ctaggatgaa tacaaatgac
      961 tagttttaaa gtcactattt attgctaaat gactgcaaaa gccagcgcct tcatgcattt
     1021 gcactatttg aaggggattc cgtggtggta aaagatgaat gtagatacag gaaattattg
     1081 atgactgact aatgattttc ttaaactcct aaagcattca caagtagacc aatgcttatg
     1141 aaaacaagct ttgcagtagc tccatctatt aacagacctt tgcctcatta ttttgtcaat
     1201 tgtttccccc caaagaataa gggtgacctt ttctttaact gcctcagagt agacagttaa
     1261 ttttcattgg tacatatttc ttagtatcta aaaatctctg tagtgtgttt caaggaagaa
     1321 aaaaaagccc agcacatgag gaatatttgt agagcagatt tcaaagtgtt acaaagaaaa
     1381 gtgcaatatg tgtcgtggca gatctctgtc aggacataca ccttgtggtt ggaccctgga
     1441 ataactccca tcttgtccca taacctgttt gtgtcttttg cagtccttta tccaaagtat
     1501 ttcccatgtg caataaagtg tttatgtatg tgattgtatt ttaaaaccta ccataagttt
     1561 aagctgtttc tatgtatgtg aaaataaaag aacagacaaa cggt
//
