LOCUS       NM_139103               1422 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus Cd48 molecule (Cd48), mRNA.
ACCESSION   NM_139103
VERSION     NM_139103.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1422)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   2  (bases 1 to 1422)
  AUTHORS   O'Connell,R.M., Chaudhuri,A.A., Rao,D.S., Gibson,W.S., Balazs,A.B.
            and Baltimore,D.
  TITLE     MicroRNAs enriched in hematopoietic stem cells differentially
            regulate long-term hematopoietic output
  JOURNAL   Proc Natl Acad Sci U S A 107 (32), 14235-14240 (2010)
   PUBMED   20660734
REFERENCE   3  (bases 1 to 1422)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 1422)
  AUTHORS   Levi,B.P., Yilmaz,O.H., Duester,G. and Morrison,S.J.
  TITLE     Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in
            the mouse hematopoietic and nervous systems
  JOURNAL   Blood 113 (8), 1670-1680 (2009)
   PUBMED   18971422
REFERENCE   5  (bases 1 to 1422)
  AUTHORS   Evans,E.J., Castro,M.A., O'Brien,R., Kearney,A., Walsh,H.,
            Sparks,L.M., Tucknott,M.G., Davies,E.A., Carmo,A.M., van der
            Merwe,P.A., Stuart,D.I., Jones,E.Y., Ladbury,J.E., Ikemizu,S. and
            Davis,S.J.
  TITLE     Crystal structure and binding properties of the CD2 and CD244
            (2B4)-binding protein, CD48
  JOURNAL   J Biol Chem 281 (39), 29309-29320 (2006)
   PUBMED   16803907
  REMARK    GeneRIF: CD48 is a CD2 and CD244 (2B4)-binding protein
REFERENCE   6  (bases 1 to 1422)
  AUTHORS   Suzuki,T., Kiyokawa,N., Taguchi,T., Sekino,T., Katagiri,Y.U. and
            Fujimoto,J.
  TITLE     CD24 induces apoptosis in human B cells via the glycolipid-enriched
            membrane domains/rafts-mediated signaling system
  JOURNAL   J Immunol 166 (9), 5567-5577 (2001)
   PUBMED   11313396
REFERENCE   7  (bases 1 to 1422)
  AUTHORS   Davis,S.J., Davies,E.A., Tucknott,M.G., Jones,E.Y. and van der
            Merwe,P.A.
  TITLE     The role of charged residues mediating low affinity protein-protein
            recognition at the cell surface by CD2
  JOURNAL   Proc Natl Acad Sci U S A 95 (10), 5490-5494 (1998)
   PUBMED   9576909
REFERENCE   8  (bases 1 to 1422)
  AUTHORS   Kato,K., Koyanagi,M., Okada,H., Takanashi,T., Wong,Y.W.,
            Williams,A.F., Okumura,K. and Yagita,H.
  TITLE     CD48 is a counter-receptor for mouse CD2 and is involved in T cell
            activation
  JOURNAL   J Exp Med 176 (5), 1241-1249 (1992)
   PUBMED   1383383
REFERENCE   9  (bases 1 to 1422)
  AUTHORS   Bujia,J., Riederer,A., Zietz,C., Wilmes,E. and Wolf,H.
  TITLE     [Oral hairy leukoplakia in human immunodeficiency virus positive
            patients: clinical and etiopathogenic aspects]
  JOURNAL   Acta Otorrinolaringol Esp 43 (6), 413-417 (1992)
   PUBMED   1299282
REFERENCE   10 (bases 1 to 1422)
  AUTHORS   Killeen,N., Moessner,R., Arvieux,J., Willis,A. and Williams,A.F.
  TITLE     The MRC OX-45 antigen of rat leukocytes and endothelium is in a
            subset of the immunoglobulin superfamily with CD2, LFA-3 and
            carcinoembryonic antigens
  JOURNAL   EMBO J 7 (10), 3087-3091 (1988)
   PUBMED   3181129
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X13016.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X13016.1, BC060542.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1422
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q24"
     gene            1..1422
                     /gene="Cd48"
                     /gene_synonym="SLAMF2"
                     /note="Cd48 molecule"
                     /db_xref="GeneID:245962"
                     /db_xref="RGD:620620"
     exon            1..107
                     /gene="Cd48"
                     /gene_synonym="SLAMF2"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..757
                     /gene="Cd48"
                     /gene_synonym="SLAMF2"
                     /note="BLAST-1; BCM1 surface antigen; MRC OX-45 surface
                     antigen; CD48 antigen; SLAM family member 2; signaling
                     lymphocytic activation molecule 2"
                     /codon_start=1
                     /product="CD48 antigen precursor"
                     /protein_id="NP_620803.1"
                     /db_xref="GeneID:245962"
                     /db_xref="RGD:620620"
                     /translation="MYFKKRRWFLILESLLLSLVTGFQDQSVPNVNAITGSNVTLTIL
                     KHPLASYQRLTWLHTTNQKILEYFPNGKKTVFESVFKDRVDLDKTNGALRIYNVSKED
                     RGDYYMRMLHETEDQWKITMEVYDLVSKPAIKIEKTKNLTDSCHLRLSCKVEDQGVDY
                     TWYEDSGPFPQRNPGYVLEITITPHNKSTFYTCQVSNPVSSENDTLYFIPPCTLARSS
                     GVHWIAAWLVVTLSIIPSILLA"
     exon            108..410
                     /gene="Cd48"
                     /gene_synonym="SLAMF2"
                     /inference="alignment:Splign:2.1.0"
     exon            411..677
                     /gene="Cd48"
                     /gene_synonym="SLAMF2"
                     /inference="alignment:Splign:2.1.0"
     exon            678..1422
                     /gene="Cd48"
                     /gene_synonym="SLAMF2"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1422
                     /gene="Cd48"
                     /gene_synonym="SLAMF2"
                     /note="polyA site"
ORIGIN      
        1 gtctccagtg tcacaggcag cttctcaaag tattatgtac ttcaaaaaac ggagatggtt
       61 tctgatcctg gaatcgcttt tgctgtcttt ggtaactgga tttcaagatc aatcagtacc
      121 aaatgtaaat gccataaccg gcagcaacgt aaccctgaca atcctgaagc acccacttgc
      181 atcgtatcaa cgtctcacct ggcttcatac taccaaccag aagattttag agtacttccc
      241 taatggtaaa aaaactgtct tcgagtctgt atttaaagac agggtcgatc ttgacaaaac
      301 aaatggtgca cttcgtatct ataatgtctc gaaagaggac agaggtgact actacatgag
      361 aatgttgcac gaaactgagg accagtggaa gataaccatg gaagtatacg atcttgtgtc
      421 caagcctgcc atcaaaatcg agaagactaa aaatttgact gactcctgtc acctgaggct
      481 atcatgtaag gtagaggacc aaggtgttga ctatacttgg tatgaggact cggggccctt
      541 tccccaaagg aatccaggat atgtactcga aatcaccatc actccacaca acaagtctac
      601 attttacacc tgccaagtca gcaatcctgt aagcagcgag aacgacacac tgtactttat
      661 tccaccttgt acgctggcca gatcttctgg agtccattgg attgcagctt ggctagtggt
      721 cacgttatcc atcattccca gcatcctgct agcctgacaa gatctctcct cagtcaagaa
      781 ggaaacatca aagccgtatc ttgccttcat cccctgcact gctcctaacc attgacgctg
      841 ctctggctcc gtggagcaaa ggaaagtgtg ttattgttat ctgtgctggt ttgaatgcat
      901 gctctatgga gtaagcacag gacctagtac agtgctacat cactgatctt tacaaagatt
      961 ctaagctaat tttttaaaaa ctgggggtag catctaattt tatataccct agttgtttcc
     1021 taacattcat tgaagataaa tgcattcctt ttaccaaaat atgtggctat cttatactaa
     1081 tgttgtttat atcactcttt ttttataaag ataaatgcat tcctttacca aaatatgtga
     1141 ctatatcatg ctaatgttgt ttatatcact cctttttgtg aagataaatg cattcctttt
     1201 accaaaatat gtgactatgt catgctaatg ttgtttatat cactcttttt tataaagata
     1261 aatgcattcc ttttaccaaa aacatgtggc tatattatac taatgttgtt tatatcactc
     1321 ttttttataa agataaatgc attccttcta ccaaaatatg tgactatatc atgctaatgt
     1381 tgtttatatc acctttttaa aaataaaatc ttttcacata ct
//
