LOCUS       NM_013169                666 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus CD3 delta subunit of T-cell receptor complex
            (Cd3d), mRNA.
ACCESSION   NM_013169
VERSION     NM_013169.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Pan,Q., Gollapudi,A.S. and Dave,V.P.
  TITLE     Biochemical evidence for the presence of a single CD3delta and
            CD3gamma chain in the surface T cell receptor/CD3 complex
  JOURNAL   J Biol Chem 279 (49), 51068-51074 (2004)
   PUBMED   15459203
REFERENCE   2  (bases 1 to 666)
  AUTHORS   Kwitek,A.E., Gullings-Handley,J., Yu,J., Carlos,D.C., Orlebeke,K.,
            Nie,J., Eckert,J., Lemke,A., Andrae,J.W., Bromberg,S., Pasko,D.,
            Chen,D., Scheetz,T.E., Casavant,T.L., Soares,M.B., Sheffield,V.C.,
            Tonellato,P.J. and Jacob,H.J.
  TITLE     High-density rat radiation hybrid maps containing over 24,000
            SSLPs, genes, and ESTs provide a direct link to the rat genome
            sequence
  JOURNAL   Genome Res 14 (4), 750-757 (2004)
   PUBMED   15060019
REFERENCE   3  (bases 1 to 666)
  AUTHORS   Sigalov,A., Aivazian,D. and Stern,L.
  TITLE     Homooligomerization of the cytoplasmic domain of the T cell
            receptor zeta chain and of other proteins containing the
            immunoreceptor tyrosine-based activation motif
  JOURNAL   Biochemistry 43 (7), 2049-2061 (2004)
   PUBMED   14967045
REFERENCE   4  (bases 1 to 666)
  AUTHORS   Dadi,H.K., Simon,A.J. and Roifman,C.M.
  TITLE     Effect of CD3delta deficiency on maturation of alpha/beta and
            gamma/delta T-cell lineages in severe combined immunodeficiency
  JOURNAL   N Engl J Med 349 (19), 1821-1828 (2003)
   PUBMED   14602880
  REMARK    Erratum:[N Engl J Med. 2004 Apr 22;350(17):1803]
REFERENCE   5  (bases 1 to 666)
  AUTHORS   Alarcon,B., Gil,D., Delgado,P. and Schamel,W.W.
  TITLE     Initiation of TCR signaling: regulation within CD3 dimers
  JOURNAL   Immunol Rev 191, 38-46 (2003)
   PUBMED   12614350
  REMARK    Review article
REFERENCE   6  (bases 1 to 666)
  AUTHORS   Chan,A.C., van Oers,N.S., Tran,A., Turka,L., Law,C.L., Ryan,J.C.,
            Clark,E.A. and Weiss,A.
  TITLE     Differential expression of ZAP-70 and Syk protein tyrosine kinases,
            and the role of this family of protein tyrosine kinases in TCR
            signaling
  JOURNAL   J Immunol 152 (10), 4758-4766 (1994)
   PUBMED   8176201
REFERENCE   7  (bases 1 to 666)
  AUTHORS   Ko,L.J., Yamamoto,M., Leonard,M.W., George,K.M., Ting,P. and
            Engel,J.D.
  TITLE     Murine and human T-lymphocyte GATA-3 factors mediate transcription
            through a cis-regulatory element within the human T-cell receptor
            delta gene enhancer
  JOURNAL   Mol Cell Biol 11 (5), 2778-2784 (1991)
   PUBMED   2017177
REFERENCE   8  (bases 1 to 666)
  AUTHORS   Kiesewetter,S., Ott,G. and Sprinzl,M.
  TITLE     The role of modified purine 64 in initiator/elongator
            discrimination of tRNA(iMet) from yeast and wheat germ
  JOURNAL   Nucleic Acids Res 18 (16), 4677-4682 (1990)
   PUBMED   2395634
REFERENCE   9  (bases 1 to 666)
  AUTHORS   Davies,J.D., Mueller,D., Wilson,D.B. and Gold,D.P.
  TITLE     Nucleotide sequence of a cDNA encoding the rat T3 delta chain
  JOURNAL   Nucleic Acids Res 18 (15), 4617 (1990)
   PUBMED   2143819
REFERENCE   10 (bases 1 to 666)
  AUTHORS   van den Elsen,P., Shepley,B.A., Cho,M. and Terhorst,C.
  TITLE     Isolation and characterization of a cDNA clone encoding the murine
            homologue of the human 20K T3/T-cell receptor glycoprotein
  JOURNAL   Nature 314 (6011), 542-544 (1985)
   PUBMED   2859526
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X53430.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X53430.1, FM074502.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q22"
     gene            1..666
                     /gene="Cd3d"
                     /note="CD3 delta subunit of T-cell receptor complex"
                     /db_xref="GeneID:25710"
                     /db_xref="RGD:2304"
     exon            1..116
                     /gene="Cd3d"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..583
                     /gene="Cd3d"
                     /note="T-cell surface glycoprotein CD3 delta chain; T-cell
                     receptor T3 delta chain; CD3 antigen delta polypeptide;
                     CD3d molecule; CD3 molecule delta polypeptide; CD3
                     molecule, delta"
                     /codon_start=1
                     /product="T-cell surface glycoprotein CD3 delta chain
                     precursor"
                     /protein_id="NP_037301.1"
                     /db_xref="GeneID:25710"
                     /db_xref="RGD:2304"
                     /translation="MEHYGILVSLLLATVLPQGSPFKIEVVEYEDKVFVNCNTSIRHL
                     DGSVERWLTKNKSLILGKGILDPRGMYMCNGTEELAKEVSTVQVYYRMCQNCVELDSA
                     TLAGVIITDLIATLLLALGVYCFAGHETGRLSGAVDTQVLLKNEQLYQPLRDRDDAQY
                     SRLGGNWPRNKRS"
     exon            117..335
                     /gene="Cd3d"
                     /inference="alignment:Splign:2.1.0"
     exon            336..467
                     /gene="Cd3d"
                     /inference="alignment:Splign:2.1.0"
     exon            468..511
                     /gene="Cd3d"
                     /inference="alignment:Splign:2.1.0"
     exon            512..664
                     /gene="Cd3d"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctcacccag gctggtcgtc cggtgacttg cctctactcc gtggatgagt ccctgtggaa
       61 gatggagcac tatggaattc tggttagtct gctactggct actgttctcc cccaagggag
      121 ccccttcaag atagaagtgg ttgaatatga ggacaaagtg tttgtgaatt gcaacaccag
      181 catcaggcat ctagatggat cagtggaaag atggttgacc aaaaataaat cactcatctt
      241 gggcaaaggc atcctggacc cacgagggat gtatatgtgt aatgggacag aggagctggc
      301 gaaggaggtg tcgactgttc aagtatatta ccgaatgtgc cagaactgtg tggagctgga
      361 ctcagccacc ctggctggtg tcatcatcac tgatctcatc gccactctgc tcctggcttt
      421 gggggtctac tgctttgcag gccatgagac cggaagactt tctggggctg ttgacactca
      481 agtcctgttg aagaacgagc agctgtatca gcctcttcga gatcgcgatg atgcccagta
      541 cagccgtctt ggagggaact ggccccggaa caaaaggtct tgagatggag gtttctcaga
      601 gtgctatatc aacggtgcct tccccttgtg ctcaaccaat aaagatgtgt tccttcagtc
      661 agcaaa
//
