LOCUS       NM_017124               1158 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Rattus norvegicus CD37 molecule (Cd37), mRNA.
ACCESSION   NM_017124
VERSION     NM_017124.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1158)
  AUTHORS   Draber,P., Vonkova,I., Stepanek,O., Hrdinka,M., Kucova,M.,
            Skopcova,T., Otahal,P., Angelisova,P., Horejsi,V., Yeung,M.,
            Weiss,A. and Brdicka,T.
  TITLE     SCIMP, a transmembrane adaptor protein involved in major
            histocompatibility complex class II signaling
  JOURNAL   Mol Cell Biol 31 (22), 4550-4562 (2011)
   PUBMED   21930792
REFERENCE   2  (bases 1 to 1158)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   3  (bases 1 to 1158)
  AUTHORS   Gartlan,K.H., Belz,G.T., Tarrant,J.M., Minigo,G., Katsara,M.,
            Sheng,K.C., Sofi,M., van Spriel,A.B., Apostolopoulos,V.,
            Plebanski,M., Robb,L. and Wright,M.D.
  TITLE     A complementary role for the tetraspanins CD37 and Tssc6 in
            cellular immunity
  JOURNAL   J Immunol 185 (6), 3158-3166 (2010)
   PUBMED   20709950
REFERENCE   4  (bases 1 to 1158)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 1158)
  AUTHORS   Knobeloch,K.P., Wright,M.D., Ochsenbein,A.F., Liesenfeld,O.,
            Lohler,J., Zinkernagel,R.M., Horak,I. and Orinska,Z.
  TITLE     Targeted inactivation of the tetraspanin CD37 impairs
            T-cell-dependent B-cell response under suboptimal costimulatory
            conditions
  JOURNAL   Mol Cell Biol 20 (15), 5363-5369 (2000)
   PUBMED   10891477
REFERENCE   6  (bases 1 to 1158)
  AUTHORS   Tomlinson,M.G. and Wright,M.D.
  TITLE     Characterisation of mouse CD37: cDNA and genomic cloning
  JOURNAL   Mol Immunol 33 (10), 867-872 (1996)
   PUBMED   8845018
REFERENCE   7  (bases 1 to 1158)
  AUTHORS   Bellacosa,A., Lazo,P.A., Bear,S.E. and Tsichlis,P.N.
  TITLE     The rat leukocyte antigen MRC OX-44 is a member of a new family of
            cell surface proteins which appear to be involved in growth
            regulation
  JOURNAL   Mol Cell Biol 11 (5), 2864-2872 (1991)
   PUBMED   2017181
REFERENCE   8  (bases 1 to 1158)
  AUTHORS   Classon,B.J., Williams,A.F., Willis,A.C., Seed,B. and
            Stamenkovic,I.
  TITLE     The primary structure of the human leukocyte antigen CD37, a
            species homologue of the rat MRC OX-44 antigen
  JOURNAL   J Exp Med 172 (3), 1007 (1990)
   PUBMED   2388030
  REMARK    Correction to:[J Exp Med. 1989 Apr 1;169(4):1497-502. doi:
            10.1084/jem.169.4.1497.. PMID: 2466944]
REFERENCE   9  (bases 1 to 1158)
  AUTHORS   Classon,B.J., Williams,A.F., Willis,A.C., Seed,B. and
            Stamenkovic,I.
  TITLE     The primary structure of the human leukocyte antigen CD37, a
            species homologue of the rat MRC OX-44 antigen
  JOURNAL   J Exp Med 169 (4), 1497-1502 (1989)
   PUBMED   2466944
  REMARK    Erratum:[J Exp Med. 1990 Sep 1;172(3):1007. doi:
            10.1084/jem.172.3.1007.. PMID: 2388030]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X53517.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X53517.1, BC059144.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680443 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1158
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="PVG/DA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..1158
                     /gene="Cd37"
                     /note="CD37 molecule"
                     /db_xref="GeneID:29185"
                     /db_xref="RGD:62035"
     exon            1..126
                     /gene="Cd37"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..903
                     /gene="Cd37"
                     /note="CD37 antigen"
                     /codon_start=1
                     /product="leukocyte antigen CD37"
                     /protein_id="NP_058820.1"
                     /db_xref="GeneID:29185"
                     /db_xref="RGD:62035"
                     /translation="MSAQESCLSLIKYFLFVFNLFFFVLGGLIFCFGTWILIDKTSFV
                     SFVGLSFVPLQTWSKVLSVSGVLTMALALLGCVGALKELRCLLGLYFGMLLLLFATQI
                     TLGILISTQRVRLERRVQELVLRTIQSYRTNPDETAAEESWDYAQFQLRCCGWQSPRD
                     WNKAQMLKANGSEELFVPCSCYNSTATNDSSGFDKLFLSQLSRLGPRAKLRQTADICA
                     LPAKAHIYREGCARSLQKWLHNNIISIVGICLGVGLLELGFMTLSIFLCRNLDHVYDR
                     LARYR"
     exon            127..199
                     /gene="Cd37"
                     /inference="alignment:Splign:2.1.0"
     exon            200..324
                     /gene="Cd37"
                     /inference="alignment:Splign:2.1.0"
     exon            325..399
                     /gene="Cd37"
                     /inference="alignment:Splign:2.1.0"
     exon            400..504
                     /gene="Cd37"
                     /inference="alignment:Splign:2.1.0"
     exon            505..741
                     /gene="Cd37"
                     /inference="alignment:Splign:2.1.0"
     exon            742..825
                     /gene="Cd37"
                     /inference="alignment:Splign:2.1.0"
     exon            826..1158
                     /gene="Cd37"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggccaacacc tcttctgtct gggttcctca agctgctcgc tccccatcta ggcgaagatg
       61 tccgcccaag agagttgcct cagcctcatc aagtacttcc tcttcgtttt caacctcttc
      121 ttctttgtac taggaggcct gattttctgc tttggcacct ggatcctcat tgacaagacc
      181 agcttcgtgt cctttgtggg cttgtccttc gtgccactgc agacctggtc caaggtcctg
      241 tcggtctcgg gtgtcctcac catggccctg gctctcctgg gctgtgtggg ggctctaaag
      301 gagctgcgct gtcttctggg cctgtatttc ggaatgctgc tgctcctgtt tgccacacag
      361 attaccttgg ggatcctcat ttccactcag cgagtccggc tggagcgaag ggtgcaggaa
      421 ttggtgttac ggaccatcca gagctaccgc acgaatccgg atgagacagc tgctgaggag
      481 agctgggact atgcgcagtt tcagctgcgc tgctgcggtt ggcaatctcc gcgggactgg
      541 aacaaggccc agatgctgaa agcaaacggg tccgaagagc tctttgtgcc ctgctcctgc
      601 tacaattcca ccgcgaccaa tgactcctcc ggctttgata agctctttct ctcccagcta
      661 agccggctgg ggccgcgggc gaagctgagg cagactgctg acatatgtgc actccccgca
      721 aaagcccata tataccgtga gggctgcgcg cggagcctcc agaagtggct gcacaacaat
      781 atcatctcca tagtgggaat ttgtctggga gtcggtcttc ttgagctcgg cttcatgaca
      841 ctctcgatat tcctgtgtag aaatctggat cacgtctatg accggctggc ccggtaccgc
      901 taggccccaa cccaccggtt ggcacccacg cacctccatg cagtcaggaa ctgtttcctt
      961 cctggttggt tacaggcttg gagccctgtg cctcaggcct cattctctgg ggacccagat
     1021 gtctgcccta agacagcctt cacttccccc acagggccag ggactttcga gcccagcttc
     1081 cttccctgct ccctcctccc cacaccatct gtctgccacc tcccacatga cacctcaaat
     1141 aaatcccctt cttttttg
//
