LOCUS       NM_001024335            1602 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus CD27 molecule (Cd27), mRNA.
ACCESSION   NM_001024335 XM_575669
VERSION     NM_001024335.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1602)
  AUTHORS   Turchinovich G and Hayday AC.
  TITLE     Skint-1 identifies a common molecular mechanism for the development
            of interferon-gamma-secreting versus interleukin-17-secreting
            gammadelta T cells
  JOURNAL   Immunity 35 (1), 59-68 (2011)
   PUBMED   21737317
REFERENCE   2  (bases 1 to 1602)
  AUTHORS   Hu MG, Deshpande A, Schlichting N, Hinds EA, Mao C, Dose M, Hu GF,
            Van Etten RA, Gounari F and Hinds PW.
  TITLE     CDK6 kinase activity is required for thymocyte development
  JOURNAL   Blood 117 (23), 6120-6131 (2011)
   PUBMED   21508411
REFERENCE   3  (bases 1 to 1602)
  AUTHORS   Zhang XG, Xu P, Liu Q, Yu CH, Zhang Y, Chen SH and Li YM.
  TITLE     Effect of tea polyphenol on cytokine gene expression in rats with
            alcoholic liver disease
  JOURNAL   Hepatobiliary Pancreat Dis Int 5 (2), 268-272 (2006)
   PUBMED   16698589
REFERENCE   4  (bases 1 to 1602)
  AUTHORS   Hase H, Kanno Y, Kojima H, Morimoto C, Okumura K and Kobata T.
  TITLE     CD27 and CD40 inhibit p53-independent mitochondrial pathways in
            apoptosis of B cells induced by B cell receptor ligation
  JOURNAL   J Biol Chem 277 (49), 46950-46958 (2002)
   PUBMED   12324477
REFERENCE   5  (bases 1 to 1602)
  AUTHORS   Furuya T, Salstrom JL, McCall-Vining S, Cannon GW, Joe B, Remmers
            EF, Griffiths MM and Wilder RL.
  TITLE     Genetic dissection of a rat model for rheumatoid arthritis:
            significant gender influences on autosomal modifier loci
  JOURNAL   Hum Mol Genet 9 (15), 2241-2250 (2000)
   PUBMED   11001927
REFERENCE   6  (bases 1 to 1602)
  AUTHORS   Simonart T, Noel JC, Andrei G, Parent D, Van Vooren JP, Hermans P,
            Lunardi-Yskandar Y, Lambert C, Dieye T, Farber CM, Liesnard C,
            Snoeck R, Heenen M and Boelaert JR.
  TITLE     Iron as a potential co-factor in the pathogenesis of Kaposi's
            sarcoma?
  JOURNAL   Int J Cancer 78 (6), 720-726 (1998)
   PUBMED   9833765
REFERENCE   7  (bases 1 to 1602)
  AUTHORS   Padanilam BJ, Lewington AJ and Hammerman MR.
  TITLE     Expression of CD27 and ischemia/reperfusion-induced expression of
            its ligand Siva in rat kidneys
  JOURNAL   Kidney Int 54 (6), 1967-1975 (1998)
   PUBMED   9853261
REFERENCE   8  (bases 1 to 1602)
  AUTHORS   Gravestein LA, Amsen D, Boes M, Calvo CR, Kruisbeek AM and Borst J.
  TITLE     The TNF receptor family member CD27 signals to Jun N-terminal
            kinase via Traf-2
  JOURNAL   Eur J Immunol 28 (7), 2208-2216 (1998)
   PUBMED   9692890
REFERENCE   9  (bases 1 to 1602)
  AUTHORS   Prasad KV, Ao Z, Yoon Y, Wu MX, Rizk M, Jacquot S and Schlossman
            SF.
  TITLE     CD27, a member of the tumor necrosis factor receptor family,
            induces apoptosis and binds to Siva, a proapoptotic protein
  JOURNAL   Proc Natl Acad Sci U S A 94 (12), 6346-6351 (1997)
   PUBMED   9177220
REFERENCE   10 (bases 1 to 1602)
  AUTHORS   Birkeland ML, Copeland NG, Gilbert DJ, Jenkins NA and Barclay AN.
  TITLE     Gene structure and chromosomal localization of the mouse homologue
            of rat OX40 protein
  JOURNAL   Eur J Immunol 25 (4), 926-930 (1995)
   PUBMED   7737295
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC095844.1.
            
            On May 27, 2005 this sequence version replaced XM_575669.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC095844.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680412, SAMN06680414
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1602
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1602
                     /gene="Cd27"
                     /gene_synonym="Tnfrsf7"
                     /note="CD27 molecule"
                     /db_xref="GeneID:500318"
                     /db_xref="RGD:1560499"
     exon            1..199
                     /gene="Cd27"
                     /gene_synonym="Tnfrsf7"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..819
                     /gene="Cd27"
                     /gene_synonym="Tnfrsf7"
                     /note="CD antigen 27; tumor necrosis factor receptor
                     superfamily, member 7; CD27 antigen"
                     /codon_start=1
                     /product="CD27 antigen precursor"
                     /protein_id="NP_001019506.1"
                     /db_xref="GeneID:500318"
                     /db_xref="RGD:1560499"
                     /translation="MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCG
                     PGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANA
                     ECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQ
                     LPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAV
                     PEELCPYSCPREEEGSVIPIQEDYRKPEPASYP"
     exon            200..331
                     /gene="Cd27"
                     /gene_synonym="Tnfrsf7"
                     /inference="alignment:Splign:2.1.0"
     exon            332..514
                     /gene="Cd27"
                     /gene_synonym="Tnfrsf7"
                     /inference="alignment:Splign:2.1.0"
     exon            515..577
                     /gene="Cd27"
                     /gene_synonym="Tnfrsf7"
                     /inference="alignment:Splign:2.1.0"
     exon            578..697
                     /gene="Cd27"
                     /gene_synonym="Tnfrsf7"
                     /inference="alignment:Splign:2.1.0"
     exon            698..1577
                     /gene="Cd27"
                     /gene_synonym="Tnfrsf7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagacaccg gtgactccgt accagcagtt ggggctcaga gaagctctcc ctgagcagga
       61 gccatggcat ggccacccct ctactggctc tgcatgctgg ggaccttggt agggctctta
      121 gctaccccag ccccaaacaa ctgtccagac agacactact ggattggggc aggactctgc
      181 tgccagatgt gtgggccagg gacattcctt gtgaagcact gtgaccagga cagagccgct
      241 gctcagtgtg atccgtgtat tccaggcacg tccttctctc cagactacca cacccggccc
      301 cactgcgaga gctgcaggca ctgtaactct ggttttctca tccgcaactg cacggtcact
      361 gccaatgctg agtgcacctg ttccaagggc tggcagtgca gggaccagga atgtacggag
      421 tgtgaccctc ctctaaaccc tgcactgact agccagccct ctgaggcccc cagcccccag
      481 ctgccaccac ccacccactt accttatgcc acagagaagc catcctggcc cccacaaagg
      541 cagcttcccg actcaactgt ctatagccgc ctgccatccc aaagacctct gtgcagctcc
      601 gactgtatcc ggatctttgt gaccttctcc agcatgcttc ttgtcttcgt cctgggtggg
      661 atcttgttct tccatcaaag aagaaatcat gggccaaatg aagatagcca ggcagtacct
      721 gaagagcttt gtccttacag ctgccctagg gaggaggagg gcagtgtcat ccctatccag
      781 gaagactacc ggaaacctga gcctgcttcc tacccttgat gcggtgctgg ggggtcggag
      841 cggggcggct ttccactgag gtagcatcca gagaactctg gctcctgccc taccaccctc
      901 atcagaacag tttcctgtgt atactcgacg gattgccctt ctgagaccga cagggacaag
      961 agcaggagcc cggtgtatgg gggagactca ggctctagct gtaaaacagc ttctaaatga
     1021 agccttccag ctggcaaagc tacttgctgg ggggcagtga gcagcacaga gtgttgttct
     1081 tccagaggac cagagtttga ttcccagcac tgtcagatgg accaaaacca gccgtaactt
     1141 tagattcaga ggatctgaca cctttgacct cctccagcac acacgcacac actggacaca
     1201 cacacactgg acacacacac aacacacaca cacactggac acacacacac tggacacaca
     1261 cacactggac acacacactg gacacacaca ctggacacac acacacacac tggacacaca
     1321 cacacactgg acacacacac acactggaca cacacacact ggacacacac acacacacac
     1381 acacacacac gatttaaaaa aaagatgtga tgagccacca gaaggactaa ctgccacaag
     1441 ggacactatc tacagacaca cagactttct ggctttggtc tgtcttctct gtaagttgtg
     1501 acagtgctgt gggaaagctg aaactgagac tttctctcag ttgcgctaaa actataaata
     1561 aaattcattt ttctataaaa aaaaaaaaaa aaaaaaaaaa aa
//
