LOCUS       NM_001394280            1797 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus CCZ1 homolog, vacuolar protein trafficking and
            biogenesis associated (Ccz1), transcript variant 1, mRNA.
ACCESSION   NM_001394280 XM_006248878
VERSION     NM_001394280.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1797)
  AUTHORS   Vaites,L.P., Paulo,J.A., Huttlin,E.L. and Harper,J.W.
  TITLE     Systematic Analysis of Human Cells Lacking ATG8 Proteins Uncovers
            Roles for GABARAPs and the CCZ1/MON1 Regulator C18orf8/RMC1 in
            Macroautophagic and Selective Autophagic Flux
  JOURNAL   Mol Cell Biol 38 (1), e00392-17 (2017)
   PUBMED   29038162
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1797)
  AUTHORS   Gerondopoulos,A., Langemeyer,L., Liang,J.R., Linford,A. and
            Barr,F.A.
  TITLE     BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine
            nucleotide exchange factor
  JOURNAL   Curr Biol 22 (22), 2135-2139 (2012)
   PUBMED   23084991
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Apr 8, 2021 this sequence version replaced XM_006248878.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360181.41256.1,
                                           SRR22582416.1128245.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-190               JAXUCZ010000012.1  15714768-15714957
            191-288             JAXUCZ010000012.1  15715766-15715863
            289-382             JAXUCZ010000012.1  15715960-15716053
            383-460             JAXUCZ010000012.1  15717343-15717420
            461-508             JAXUCZ010000012.1  15717779-15717826
            509-592             JAXUCZ010000012.1  15719439-15719522
            593-768             JAXUCZ010000012.1  15722389-15722564
            769-850             JAXUCZ010000012.1  15725764-15725845
            851-912             JAXUCZ010000012.1  15728401-15728462
            913-1024            JAXUCZ010000012.1  15728733-15728844
            1025-1058           JAXUCZ010000012.1  15734054-15734087
            1059-1176           JAXUCZ010000012.1  15734854-15734971
            1177-1335           JAXUCZ010000012.1  15735819-15735977
            1336-1463           JAXUCZ010000012.1  15736388-15736515
            1464-1797           JAXUCZ010000012.1  15737940-15738273
FEATURES             Location/Qualifiers
     source          1..1797
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12p11"
     gene            1..1797
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /note="CCZ1 homolog, vacuolar protein trafficking and
                     biogenesis associated"
                     /db_xref="GeneID:360768"
                     /db_xref="RGD:1306410"
     exon            1..190
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..1519
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /note="isoform 1 is encoded by transcript variant 1;
                     vacuolar fusion protein CCZ1 homolog; CCZ1 vacuolar
                     protein trafficking and biogenesis associated homolog;
                     CCZ1 homolog, vacuolar protein trafficking and biogenesis
                     associated B; CCZ1 homolog B, vacuolar protein trafficking
                     and biogenesis associated"
                     /codon_start=1
                     /product="vacuolar fusion protein CCZ1 homolog isoform 1"
                     /protein_id="NP_001381209.1"
                     /db_xref="GeneID:360768"
                     /db_xref="RGD:1306410"
                     /translation="MAAAAAGTGTWAAQEKQFPPALLSFFIYNPRFGPREGEEENKIL
                     FYHPNEVEKNEKIRNVGLCEAIVQFTRTFSPSKPAKSLHTQKNRQFFNEPEENFWMVM
                     VVRNPIIEKQSKDGKAVVEYQEEELLDKVYSSVLQQCYSMYKLFNGTFLKAMEDGGVK
                     LLKERLEKFFHRYLQTLHLQSCDLLDIFGGISFFPLDKMTYLKIQSFINRMEESLSVV
                     KYTAFLYNDQLIWSGLEQDDMRILYKYLTTSLFPRHIEPELAGRDSPVRAEMPGNLQH
                     YGRFLTGPLNLNDPEAKCRFPKIFVNTDDTYEELHLIVYKAMSAAVCFMIDASTQLTL
                     DFCRRLDSIVGPQLTVLASDICEQFNINKRISGSEKEPQFKFIYFNHMNLAEKSTIHM
                     RKTPSVSLTSVHPDLMKILGDINSDFTRADEDEEIIVKAMSDYWVVGKKSDQRELYVI
                     LNQKNANLIEVNEEVKKLCATQFNNIFFLD"
     exon            191..288
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     exon            289..382
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     exon            383..460
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     exon            461..508
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     exon            509..592
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     exon            593..768
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     exon            769..850
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     exon            851..912
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1024
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..1058
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1176
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1335
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     exon            1336..1463
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
     exon            1464..1797
                     /gene="Ccz1"
                     /gene_synonym="Ccz1b; RGD1306410"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaagtgcgg tgttccctaa ggctgcggtc tccgagcggg cggaggcgag cctcccgaag
       61 tgggggcccg gccggaatgg cggcagcggc ggccgggaca gggacttggg cagcccagga
      121 aaagcagttc ccgccggcgc tgttgagctt cttcatctac aacccacgtt tcgggccgcg
      181 agagggagag gaagaaaata aaattttgtt ttaccatcca aatgaagtag aaaagaatga
      241 aaaaattaga aatgttggat tatgtgaagc aatcgtacag tttacaagga cttttagccc
      301 atcgaaacct gcaaaatctt tacacacaca gaagaataga cagttcttca atgaaccaga
      361 agaaaatttc tggatggtca tggttgttcg gaatcctatc atcgaaaagc agagtaaaga
      421 tggcaaggcg gtagtggagt accaagagga ggaactgttg gacaaggtgt atagctcagt
      481 gctccagcag tgctacagca tgtacaagct ttttaatggg acgtttctga aagccatgga
      541 agatggaggt gtcaagctcc taaaagagag attagagaaa ttcttccatc ggtatttgca
      601 gacgctgcat ttgcaatcat gtgacctcct ggatatcttt ggtgggatca gcttcttccc
      661 gttggataaa atgacttact tgaaaatcca gtcctttatt aaccgaatgg aagaaagcct
      721 gagtgtagtc aaatacacag cattcctgta caacgaccaa ctcatctgga gtggactaga
      781 acaagatgac atgagaattt tgtacaaata cctcaccacc tcactgttcc ccagacacat
      841 cgaacctgag ttggcgggaa gggattcccc agtaagggcg gaaatgccgg gaaatcttca
      901 acactacgga agatttctta ctggaccctt gaaccttaat gatccagaag caaaatgcag
      961 attccccaaa atttttgtaa atacagatga cacttatgaa gagctccatt taattgttta
     1021 taaggccatg agcgcagctg tctgcttcat gatcgacgcc tccacgcagc tcacgctgga
     1081 tttctgccga agattggaca gcattgtcgg gccgcagctc acagtgctgg catctgacat
     1141 ctgtgagcag tttaatatca acaagagaat ctctgggtct gaaaaagagc cccagtttaa
     1201 gttcatctac ttcaaccaca tgaatttagc agagaaaagt acaattcaca tgaggaagac
     1261 gcccagcgtg tcactcacgt ccgtccaccc ggatctaatg aagattctag gggacatcaa
     1321 cagtgacttt accagagcag atgaagatga agagatcatt gtgaaagcca tgagcgacta
     1381 ctgggttgtg gggaagaagt ctgaccagcg ggagctctac gtgattctca atcagaagaa
     1441 cgcgaacctg atcgaggtca atgaagaggt gaagaaactc tgcgccacgc agttcaacaa
     1501 catcttcttc ttggattgac tctaacggct cacaacacat ctttaaaaac ctcagcaaac
     1561 ctttgtttac cattacaact tactggtcat gatagtgact gggtcagtga cactcgtaaa
     1621 gcaatacccg ctttgagaaa tcgatttcta cttggtctga tgattccccg aggtttttag
     1681 atgttagata tctatgtgga attaattata gtcagctggc tgtcatccca tcccgctgac
     1741 atcacgtgga tattttactg ggaaaggaga gtaataaatt gttaaagttt ttaaaaa
//
