LOCUS       NM_001106603            2486 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus chaperonin containing TCP1 subunit 7 (Cct7),
            mRNA.
ACCESSION   NM_001106603 XM_001073942 XM_216180
VERSION     NM_001106603.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2486)
  AUTHORS   Freund A, Zhong FL, Venteicher AS, Meng Z, Veenstra TD, Frydman J
            and Artandi SE.
  TITLE     Proteostatic control of telomerase function through TRiC-mediated
            folding of TCAB1
  JOURNAL   Cell 159 (6), 1389-1403 (2014)
   PUBMED   25467444
REFERENCE   2  (bases 1 to 2486)
  AUTHORS   Slater LH, Hett EC, Clatworthy AE, Mark KG and Hung DT.
  TITLE     CCT chaperonin complex is required for efficient delivery of
            anthrax toxin into the cytosol of host cells
  JOURNAL   Proc Natl Acad Sci U S A 110 (24), 9932-9937 (2013)
   PUBMED   23716698
REFERENCE   3  (bases 1 to 2486)
  AUTHORS   Knee KM, Sergeeva OA and King JA.
  TITLE     Human TRiC complex purified from HeLa cells contains all eight CCT
            subunits and is active in vitro
  JOURNAL   Cell Stress Chaperones 18 (2), 137-144 (2013)
   PUBMED   23011926
REFERENCE   4  (bases 1 to 2486)
  AUTHORS   Dun MD, Smith ND, Baker MA, Lin M, Aitken RJ and Nixon B.
  TITLE     The chaperonin containing TCP1 complex (CCT/TRiC) is involved in
            mediating sperm-oocyte interaction
  JOURNAL   J Biol Chem 286 (42), 36875-36887 (2011)
   PUBMED   21880732
REFERENCE   5  (bases 1 to 2486)
  AUTHORS   Bharti P, Schliebs W, Schievelbusch T, Neuhaus A, David C, Kock K,
            Herrmann C, Meyer HE, Wiese S, Warscheid B, Theiss C and Erdmann R.
  TITLE     PEX14 is required for microtubule-based peroxisome motility in
            human cells
  JOURNAL   J Cell Sci 124 (Pt 10), 1759-1768 (2011)
   PUBMED   21525035
REFERENCE   6  (bases 1 to 2486)
  AUTHORS   Mukherjee K, Conway de Macario E, Macario AJ and Brocchieri L.
  TITLE     Chaperonin genes on the rise: new divergent classes and intense
            duplication in human and other vertebrate genomes
  JOURNAL   BMC Evol Biol 10, 64 (2010)
   PUBMED   20193073
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 2486)
  AUTHORS   Hanafy KA, Martin E and Murad F.
  TITLE     CCTeta, a novel soluble guanylyl cyclase-interacting protein
  JOURNAL   J Biol Chem 279 (45), 46946-46953 (2004)
   PUBMED   15347653
  REMARK    GeneRIF: CCTeta is a novel soluble guanylyl cyclase-interacting
            protein
REFERENCE   8  (bases 1 to 2486)
  AUTHORS   Suzuki H, Fukunishi Y, Kagawa I, Saito R, Oda H, Endo T, Kondo S,
            Bono H, Okazaki Y and Hayashizaki Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
REFERENCE   9  (bases 1 to 2486)
  AUTHORS   Hynes G, Kubota H and Willison KR.
  TITLE     Antibody characterisation of two distinct conformations of the
            chaperonin-containing TCP-1 from mouse testis
  JOURNAL   FEBS Lett 358 (2), 129-132 (1995)
   PUBMED   7828721
REFERENCE   10 (bases 1 to 2486)
  AUTHORS   Kubota H, Hynes G, Carne A, Ashworth A and Willison K.
  TITLE     Identification of six Tcp-1-related genes encoding divergent
            subunits of the TCP-1-containing chaperonin
  JOURNAL   Curr Biol 4 (2), 89-99 (1994)
   PUBMED   7953530
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473957.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_216180.3, XM_001073942.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ214319.1, FQ218957.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2486
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..2486
                     /gene="Cct7"
                     /note="chaperonin containing TCP1 subunit 7"
                     /db_xref="GeneID:297406"
                     /db_xref="RGD:1306422"
     exon            1..655
                     /gene="Cct7"
                     /inference="alignment:Splign:2.1.0"
     CDS             650..2284
                     /gene="Cct7"
                     /note="chaperonin subunit 7 (eta); chaperonin containing
                     Tcp1, subunit 7 (eta)"
                     /codon_start=1
                     /product="T-complex protein 1 subunit eta"
                     /protein_id="NP_001100073.1"
                     /db_xref="GeneID:297406"
                     /db_xref="RGD:1306422"
                     /translation="MMPTPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRG
                     MDKLIVDGRGKATISNDGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAA
                     EFLKQVKPYVEEGLHPQIIIRAFRTATQLAVNKIKEIAVTVKKQDKVEQRKMLEKCAM
                     TALSSKLISQQKVFFAKMVVDAVMMLDELLQLKMIGIKKVQGGALEESRLVAGVAFKK
                     TFSYAGFEMQPKKYKNPKIALLNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYD
                     KLEKIHQSGAKVILSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSV
                     NALIPDVLGRCQVFEETQIGGERYNFFTGCPKAKTCTIILRGGAEQFMEETERSLHDA
                     IMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLC
                     DNAGFDATNILNKLRARHAQGGMWYGVDINNEDIADNFQAFVWEPAMVRINALTAASE
                     AACLIVSVDETIKNPRSTVDAPAPAAGRGRGQGRFH"
     exon            656..809
                     /gene="Cct7"
                     /inference="alignment:Splign:2.1.0"
     exon            810..916
                     /gene="Cct7"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1042
                     /gene="Cct7"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1095
                     /gene="Cct7"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..1267
                     /gene="Cct7"
                     /inference="alignment:Splign:2.1.0"
     exon            1268..1432
                     /gene="Cct7"
                     /inference="alignment:Splign:2.1.0"
     exon            1433..1621
                     /gene="Cct7"
                     /inference="alignment:Splign:2.1.0"
     exon            1622..1719
                     /gene="Cct7"
                     /inference="alignment:Splign:2.1.0"
     exon            1720..1852
                     /gene="Cct7"
                     /inference="alignment:Splign:2.1.0"
     exon            1853..2059
                     /gene="Cct7"
                     /inference="alignment:Splign:2.1.0"
     exon            2060..2486
                     /gene="Cct7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcactcctca ttttagacgc acctccccga tcctggggtg ggcggcttgc gggggacgcg
       61 cgggattcac ggatctcctt ccagtcagag gctggccccg gcaaggcggc gcctcagccg
      121 acaagaggcg ccacagagct agaagccgct ctgataaagt ttcccgcgcc cgagcgggct
      181 gcgcacctgt gacccgggac actgttctca acttcccagg ctacctatga aacgcacaga
      241 gctccgaggc cccggggccg tgtggttgca gtgagatcac tcacctaagg tgcttctcac
      301 agccggtgtt cagtgttgac atttcattgc acgtctacca tggtgcctgg gtacgcgggc
      361 tgaaggtggg accttactgc accctcccag accaaaagca caacgaaact cgatgacccc
      421 gccaaagcta actcgagttc ctagagcgtc cctgggcctc cgacgcttct agccggccac
      481 ctcttagcta accatagagt ggcggaagtg gtccgttctc ttcctctccc gggctaacgt
      541 ctcgccagaa gcttctgggg acttctccgg cgcggagcat tgtgggcttg ggtgggcggc
      601 ccctaggcgg agaacagacg agttgcgggt acctgaaacc gcttccaaga tgatgcccac
      661 acctgttatc ctgttgaaag agggtactga tagctcccaa ggcatccctc agcttgtgag
      721 taacatcagt gcctgccaag tgattgctga ggctgtaaga accaccctgg gtccccgtgg
      781 catggacaaa cttattgtgg atggccgagg caaagcaaca atttctaatg atggggccac
      841 aattctgaaa ctccttgatg ttgtccatcc tgcagcaaag actttagtgg atattgccaa
      901 atcccaagac gctgaggttg gtgatggcac cacctcagtg accctgctgg ctgcggagtt
      961 tctgaagcag gtgaagccct acgtggagga aggtttacac cctcagatca tcatcagagc
     1021 cttccgcaca gccacccagt tggctgttaa taaaatcaaa gagatagctg tgaccgtgaa
     1081 gaagcaagat aaagtagaac agaggaagat gctagagaag tgtgcaatga ctgccctgag
     1141 ctccaagctg atctcccagc agaaggtctt ctttgccaag atggtggttg atgctgtgat
     1201 gatgcttgac gagttgctgc agcttaaaat gattggcatc aagaaggtgc agggtggagc
     1261 cctggaggag tctcgactag tggctggtgt tgcgttcaag aagacgttct cttatgctgg
     1321 gtttgaaatg cagcccaaga agtataagaa ccccaagatt gccctcttaa atgttgagct
     1381 tgaactgaaa gcagagaaag ataatgctga aatcagggtc cacacagtgg aggattacca
     1441 ggcaattgtt gatgccgagt ggaacattct ctatgacaag ttagagaaga ttcatcagtc
     1501 tggagccaaa gtcatcttgt ctaaactccc tattggggat gtggccaccc agtactttgc
     1561 tgatagggac atgttctgtg ctggccgtgt acctgaggag gatctgaaga ggacgatgat
     1621 ggcttgtgga ggctcaatcc agaccagtgt gaatgctctg attccagatg tgctgggccg
     1681 ctgccaggtg tttgaagaga cccaaattgg aggagagagg tacaatttct tcactggctg
     1741 ccctaaggcc aagacatgta cgatcattct ccgtggtggt gctgagcagt ttatggagga
     1801 gacagagagg tccctacatg atgccatcat gattgtgagg agggccatca agaacgactc
     1861 tgtggtggct ggtggtggag ccattgagat ggagctttcc aaatacctgc gggactactc
     1921 aaggaccatt ccagggaaac agcagctgtt gatcggggca tatgccaagg ccctggagat
     1981 tattccacga cagctgtgtg acaacgctgg ctttgatgcc acaaacatcc tcaacaaact
     2041 gcgggctcga catgcacagg ggggcatgtg gtatggggtg gacatcaaca acgaggacat
     2101 tgctgacaac ttccaggcat ttgtgtggga gccagccatg gtgcgcatca acgctctgac
     2161 agcagcttct gaggctgcgt gcctgattgt gtctgtggat gagactatca agaacccccg
     2221 ctccactgtg gatgctccag ctccagcagc tggccggggc agaggccagg gccgcttcca
     2281 ttgagaggca gtccgcatac ctccttgtga ggtgtattgg ggggtgagaa aaatggttag
     2341 tcttaactgt gctctcactg gaggttattt aaataaaaat taaggttact tggtcagagt
     2401 tttttttttt tccataaaca tcttcctgcc ttagaatttg agttatgtgt acttggaaat
     2461 agaaataaag aactgtgttg gcctgc
//
