LOCUS       NM_001004078            1766 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus chaperonin containing TCP1 subunit 5 (Cct5),
            mRNA.
ACCESSION   NM_001004078 XM_215516
VERSION     NM_001004078.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1766)
  AUTHORS   Freund,A., Zhong,F.L., Venteicher,A.S., Meng,Z., Veenstra,T.D.,
            Frydman,J. and Artandi,S.E.
  TITLE     Proteostatic control of telomerase function through TRiC-mediated
            folding of TCAB1
  JOURNAL   Cell 159 (6), 1389-1403 (2014)
   PUBMED   25467444
REFERENCE   2  (bases 1 to 1766)
  AUTHORS   Tracy,C.M., Gray,A.J., Cuellar,J., Shaw,T.S., Howlett,A.C.,
            Taylor,R.M., Prince,J.T., Ahn,N.G., Valpuesta,J.M. and
            Willardson,B.M.
  TITLE     Programmed cell death protein 5 interacts with the cytosolic
            chaperonin containing tailless complex polypeptide 1 (CCT) to
            regulate beta-tubulin folding
  JOURNAL   J Biol Chem 289 (7), 4490-4502 (2014)
   PUBMED   24375412
REFERENCE   3  (bases 1 to 1766)
  AUTHORS   Slater,L.H., Hett,E.C., Clatworthy,A.E., Mark,K.G. and Hung,D.T.
  TITLE     CCT chaperonin complex is required for efficient delivery of
            anthrax toxin into the cytosol of host cells
  JOURNAL   Proc Natl Acad Sci U S A 110 (24), 9932-9937 (2013)
   PUBMED   23716698
REFERENCE   4  (bases 1 to 1766)
  AUTHORS   Knee,K.M., Sergeeva,O.A. and King,J.A.
  TITLE     Human TRiC complex purified from HeLa cells contains all eight CCT
            subunits and is active in vitro
  JOURNAL   Cell Stress Chaperones 18 (2), 137-144 (2013)
   PUBMED   23011926
REFERENCE   5  (bases 1 to 1766)
  AUTHORS   Dun,M.D., Smith,N.D., Baker,M.A., Lin,M., Aitken,R.J. and Nixon,B.
  TITLE     The chaperonin containing TCP1 complex (CCT/TRiC) is involved in
            mediating sperm-oocyte interaction
  JOURNAL   J Biol Chem 286 (42), 36875-36887 (2011)
   PUBMED   21880732
REFERENCE   6  (bases 1 to 1766)
  AUTHORS   Werner,H.B., Kuhlmann,K., Shen,S., Uecker,M., Schardt,A.,
            Dimova,K., Orfaniotou,F., Dhaunchak,A., Brinkmann,B.G., Mobius,W.,
            Guarente,L., Casaccia-Bonnefil,P., Jahn,O. and Nave,K.A.
  TITLE     Proteolipid protein is required for transport of sirtuin 2 into CNS
            myelin
  JOURNAL   J Neurosci 27 (29), 7717-7730 (2007)
   PUBMED   17634366
REFERENCE   7  (bases 1 to 1766)
  AUTHORS   Leong,W.F. and Chow,V.T.
  TITLE     Transcriptomic and proteomic analyses of rhabdomyosarcoma cells
            reveal differential cellular gene expression in response to
            enterovirus 71 infection
  JOURNAL   Cell Microbiol 8 (4), 565-580 (2006)
   PUBMED   16548883
REFERENCE   8  (bases 1 to 1766)
  AUTHORS   Takagi,M., Absalon,M.J., McLure,K.G. and Kastan,M.B.
  TITLE     Regulation of p53 translation and induction after DNA damage by
            ribosomal protein L26 and nucleolin
  JOURNAL   Cell 123 (1), 49-63 (2005)
   PUBMED   16213212
  REMARK    Erratum:[Cell. 2005 Nov 4;123(3):536-7]
REFERENCE   9  (bases 1 to 1766)
  AUTHORS   Hynes,G., Kubota,H. and Willison,K.R.
  TITLE     Antibody characterisation of two distinct conformations of the
            chaperonin-containing TCP-1 from mouse testis
  JOURNAL   FEBS Lett 358 (2), 129-132 (1995)
   PUBMED   7828721
REFERENCE   10 (bases 1 to 1766)
  AUTHORS   Kubota,H., Hynes,G., Carne,A., Ashworth,A. and Willison,K.
  TITLE     Identification of six Tcp-1-related genes encoding divergent
            subunits of the TCP-1-containing chaperonin
  JOURNAL   Curr Biol 4 (2), 89-99 (1994)
   PUBMED   7953530
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079441.1.
            
            On Sep 6, 2004 this sequence version replaced XM_215516.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079441.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1766
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q23"
     gene            1..1766
                     /gene="Cct5"
                     /note="chaperonin containing TCP1 subunit 5"
                     /db_xref="GeneID:294864"
                     /db_xref="RGD:735161"
     exon            1..107
                     /gene="Cct5"
                     /inference="alignment:Splign:2.1.0"
     CDS             3..1628
                     /gene="Cct5"
                     /note="CCT-epsilon; TCP-1-epsilon; chaperonin subunit 5
                     (epsilon); chaperonin containing Tcp1, subunit 5
                     (epsilon)"
                     /codon_start=1
                     /product="T-complex protein 1 subunit epsilon"
                     /protein_id="NP_001004078.1"
                     /db_xref="GeneID:294864"
                     /db_xref="RGD:735161"
                     /translation="MASVGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAV
                     ANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEI
                     GDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARIAIQHLDKISDNVLVDIN
                     NPEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGR
                     LEDTKLIKGVIVDKDFSHPQMPKEVLNAKIAILTCPFEPPKPKTKHKLDVTSVEDYKA
                     LQKYEKEKFEEMIAQIKETGANLAICQWGFDDEANHLLLQNGLPAVRWVGGPEIELIA
                     IATGGRIVPRFSELTSEKLGFAGVVREISFGTTKDKMLVIEQCKNSRAVTIFIRGGNK
                     MIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRA
                     FADALEVIPMALSENSGMNPIQTMTEVRARQVKESNPALGIDCLHKGSNDMQYQHVIE
                     TLIGKKQQISLATQMVRMILKIDDIRKPGESEE"
     exon            108..168
                     /gene="Cct5"
                     /inference="alignment:Splign:2.1.0"
     exon            169..333
                     /gene="Cct5"
                     /inference="alignment:Splign:2.1.0"
     exon            334..532
                     /gene="Cct5"
                     /inference="alignment:Splign:2.1.0"
     exon            533..725
                     /gene="Cct5"
                     /inference="alignment:Splign:2.1.0"
     exon            726..875
                     /gene="Cct5"
                     /inference="alignment:Splign:2.1.0"
     exon            876..995
                     /gene="Cct5"
                     /inference="alignment:Splign:2.1.0"
     exon            996..1181
                     /gene="Cct5"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..1319
                     /gene="Cct5"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1500
                     /gene="Cct5"
                     /inference="alignment:Splign:2.1.0"
     exon            1501..1739
                     /gene="Cct5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccatggcgtc cgtggggacc ctcgccttcg atgagtatgg gcgccccttt cttattatca
       61 aggaccaaga tcgcaagtct cgtctcatgg ggcttgaggc cctcaagtct cacatcatgg
      121 ctgccaaagc tgtagcaaac acaatgcgga cgtcactggg accaaacggg ctggataaga
      181 tgatggttga taaggatggt gatgtgactg tgaccaacga tggtgccacc attctaagca
      241 tgatggatgt tgatcatcag attgccaagc tgatggttga actgtccaaa tcccaggatg
      301 atgaaattgg agatgggacc acaggagtgg ttgtcttggc tggtgccctg ttggaagaag
      361 ctgagcagct gctggaccga ggcatccatc ctatcagaat tgctgatggc tacgaacagg
      421 ccgcccgaat tgctattcag cacctggaca aaatcagcga taatgtgctt gttgacataa
      481 acaaccccga acctctgatt cagactgcaa aaaccacact gggctccaaa gtggttaaca
      541 gctgtcaccg acaaatggct gagattgccg tcaatgctgt cctcacagtg gctgatatgg
      601 agcggagaga tgttgacttt gagctcatca aagtggaagg caaagtaggt gggcggctgg
      661 aggacaccaa acttataaag ggtgtgatcg ttgataagga cttcagtcac ccacagatgc
      721 cgaaagaagt gttgaatgct aagattgcaa ttctcacgtg tccatttgaa ccacctaaac
      781 caaagacaaa gcacaagttg gatgtcacat ctgtggagga ctacaaagcc ctgcagaagt
      841 acgaaaagga aaagtttgaa gagatgattg cgcagataaa agaaactggt gctaacctag
      901 ctatttgcca gtggggcttt gatgatgaag ctaatcattt acttcttcag aacggcctgc
      961 ctgcagttcg ctgggtagga ggacctgaga ttgagctgat cgccattgca acaggaggcc
     1021 ggattgtccc aaggttctca gagcttacct ctgagaagct gggctttgcc ggtgtggtgc
     1081 gggagatctc atttggcact acaaaagaca aaatgctggt tattgagcag tgtaagaact
     1141 ctagagctgt gaccattttc atcagaggag gaaacaagat gatcattgaa gaagcaaaac
     1201 gatctctcca tgatgccctg tgtgtcatcc ggaacctcat ccgtgataac cgtgttgtgt
     1261 atggaggagg ggcagctgaa atatcctgcg ccctggcagt cagccaagag gcagacaagt
     1321 gccccactct ggaacagtac gccatgagag ctttcgcaga cgccttggag gtcatcccca
     1381 tggccctttc agaaaacagt ggcatgaatc ccatccagac catgactgaa gtccgagcta
     1441 gacaagtgaa ggagtctaac cctgccctgg ggattgactg tctgcacaag ggcagtaatg
     1501 atatgcagta tcagcatgtc atagaaacct tgattggtaa aaagcagcag atctctcttg
     1561 ccacacagat ggttaggatg attctgaaga ttgatgacat ccgtaagcct ggagaatctg
     1621 aagaataaac tgtaccatta ccactgtgat taaataaagg gtgtgtagta ctgcgtctgc
     1681 agttactgct cgtcctctca cagcctgtag atgctggaat aaaagcagct gtttggtaaa
     1741 aaaaaaaaaa aaaaaaaaaa aaaaaa
//
