LOCUS       NM_001108501            5125 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus centriolar coiled-coil protein 110 (Ccp110),
            mRNA.
ACCESSION   NM_001108501 XM_001078870 XM_341914
VERSION     NM_001108501.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5125)
  AUTHORS   Wang,C., Li,J., Takemaru,K.I., Jiang,X., Xu,G. and Wang,B.
  TITLE     Centrosomal protein Dzip1l binds Cby, promotes ciliary bud
            formation, and acts redundantly with Bromi to regulate ciliogenesis
            in the mouse
  JOURNAL   Development 145 (6) (2018)
   PUBMED   29487109
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5125)
  AUTHORS   Yadav,S.P., Sharma,N.K., Liu,C., Dong,L., Li,T. and Swaroop,A.
  TITLE     Centrosomal protein CP110 controls maturation of the mother
            centriole during cilia biogenesis
  JOURNAL   Development 143 (9), 1491-1501 (2016)
   PUBMED   26965371
REFERENCE   3  (bases 1 to 5125)
  AUTHORS   Kobayashi,T., Kim,S., Lin,Y.C., Inoue,T. and Dynlacht,B.D.
  TITLE     The CP110-interacting proteins Talpid3 and Cep290 play overlapping
            and distinct roles in cilia assembly
  JOURNAL   J Cell Biol 204 (2), 215-229 (2014)
   PUBMED   24421332
REFERENCE   4  (bases 1 to 5125)
  AUTHORS   Li,J., D'Angiolella,V., Seeley,E.S., Kim,S., Kobayashi,T., Fu,W.,
            Campos,E.I., Pagano,M. and Dynlacht,B.D.
  TITLE     USP33 regulates centrosome biogenesis via deubiquitination of the
            centriolar protein CP110
  JOURNAL   Nature 495 (7440), 255-259 (2013)
   PUBMED   23486064
REFERENCE   5  (bases 1 to 5125)
  AUTHORS   Courtois,A., Schuh,M., Ellenberg,J. and Hiiragi,T.
  TITLE     The transition from meiotic to mitotic spindle assembly is gradual
            during early mammalian development
  JOURNAL   J Cell Biol 198 (3), 357-370 (2012)
   PUBMED   22851319
REFERENCE   6  (bases 1 to 5125)
  AUTHORS   Spektor,A., Tsang,W.Y., Khoo,D. and Dynlacht,B.D.
  TITLE     Cep97 and CP110 suppress a cilia assembly program
  JOURNAL   Cell 130 (4), 678-690 (2007)
   PUBMED   17719545
REFERENCE   7  (bases 1 to 5125)
  AUTHORS   Kleylein-Sohn,J., Westendorf,J., Le Clech,M., Habedanck,R.,
            Stierhof,Y.D. and Nigg,E.A.
  TITLE     Plk4-induced centriole biogenesis in human cells
  JOURNAL   Dev Cell 13 (2), 190-202 (2007)
   PUBMED   17681131
REFERENCE   8  (bases 1 to 5125)
  AUTHORS   Tsang,W.Y., Spektor,A., Luciano,D.J., Indjeian,V.B., Chen,Z.,
            Salisbury,J.L., Sanchez,I. and Dynlacht,B.D.
  TITLE     CP110 cooperates with two calcium-binding proteins to regulate
            cytokinesis and genome stability
  JOURNAL   Mol Biol Cell 17 (8), 3423-3434 (2006)
   PUBMED   16760425
REFERENCE   9  (bases 1 to 5125)
  AUTHORS   Habedanck,R., Stierhof,Y.D., Wilkinson,C.J. and Nigg,E.A.
  TITLE     The Polo kinase Plk4 functions in centriole duplication
  JOURNAL   Nat Cell Biol 7 (11), 1140-1146 (2005)
   PUBMED   16244668
REFERENCE   10 (bases 1 to 5125)
  AUTHORS   Chen,Z., Indjeian,V.B., McManus,M., Wang,L. and Dynlacht,B.D.
  TITLE     CP110, a cell cycle-dependent CDK substrate, regulates centrosome
            duplication in human cells
  JOURNAL   Dev Cell 3 (3), 339-350 (2002)
   PUBMED   12361598
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473956.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_341914.3, XM_001078870.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMD00132262, SAMD00132268
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5125
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q35"
     gene            1..5125
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /note="centriolar coiled-coil protein 110"
                     /db_xref="GeneID:361634"
                     /db_xref="RGD:1310509"
     exon            1..138
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            139..279
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            280..434
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     CDS             294..3317
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /note="centrosomal protein of 110 kDa; centriolar coiled
                     coil protein 110kDa"
                     /codon_start=1
                     /product="centriolar coiled-coil protein of 110 kDa"
                     /protein_id="NP_001101971.1"
                     /db_xref="GeneID:361634"
                     /db_xref="RGD:1310509"
                     /translation="MEEYEKFCEKALARAQEASLSTDSFLPAQAESVSLIRFHGVAVL
                     SPLLTIEKREKIQQEKQKALDVQTRKQANRKKALLTRVQEILENVQVRKAPNASDFDQ
                     WATETIASNSEVTGLSVPVTVPSDLLSPTEHCTSGKLGKTTGLLPVNNEDQQSPERMG
                     LPKDSEVFGSLKQCESPGSRWAENGAAPRLSSASSQETVISDDPLLAKEEQEPSCLAE
                     VTPDPYIISLQNLMKRSKEYVEREQSSWSLRSSLKKSVHETHSDKENDAAKASDCVKE
                     KAPPMPVGRHCGSAIPDKPSLNKSNVLLQGASQASSLGTSVLASFLKTDLPVGTGPPT
                     VPDAESDFKVIPTFVTENKVKSLIGPYAKLPSPEPSMSPTMHRRHSRSSSACQILINN
                     PVNACELSPKGKEEAVDRIAPAAAETNESEIVPKPPTDLTGVGSSKVSATKVMSDTIR
                     EMVMGKPSQVHQALGNQLGNNVTVEQFAMEGPFIPDGRGMQKVDGTCIAVPKLHELQP
                     TSQCVSSQTLEDACGLKAASVLAKNSCNVQMELNKSYDVKRPSPLLMQTQNSRQQMDT
                     PPVPRGNEQFVDNSFEKVKRRLDLDVDSLQKENCPHILTAGSAEQERERPPERRYPKG
                     SVYGNKNKMLETSPKEGQELLKSKMLAFEEMRKRLEEQHVQQLSLLIAEQEREQEQLQ
                     KEIEEQEKMLKEKAVTTDVSGLNSALELEWRKRSDPAFLETMLSQVDSLQTSNNSGFL
                     SSALQYSFGSASEVPLYLRGSLTSGVTKLSVTRPFGRAQPKWSQVFSPEIQAKFNKIT
                     AVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLA
                     QLRAALYGIHDIFFVMDAAERMSILHHDREARKEKLLRQMDKMRSPRVALSVATQKSL
                     DRKKFMKVAEMGMANKKFLLKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVV
                     QNRQKPSQSRVPNRAPVSGAYAGKTQRKRPNVATI"
     exon            435..563
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            564..2211
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            2212..2342
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            2343..2505
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            2506..2645
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            2646..2762
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            2763..2864
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            2865..2981
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            2982..3055
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            3056..3118
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            3119..3178
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            3179..3264
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
     exon            3265..5125
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggacccgta atatggcggg gaggagaagg aggagaaggc ggcgaaccca gatgcgctct
       61 gactgaaccg actgaggcct ttgcttatta aggaggctgg tccacgggca gagaagctga
      121 tcgggcggtg ggtgtcaggc gcctgctgtg tgctgacacc attctgtgcc atgggactca
      181 gtgagcaaga ctgagaagga cctgttctat ggagcttacg cttcggtggg agaagacaca
      241 caaaactcac ggcagtacag gaggccattt cagatagtgt gtgtggtggg aacatggagg
      301 aatatgagaa gttctgcgag aaagcgcttg cccgagctca ggaagcatca ctgtccacag
      361 acagcttcct gcccgcccag gcagaaagtg tctcactcat ccgtttccat ggggtggctg
      421 tactttctcc actgcttacc attgagaaga gagagaaaat tcaacaggaa aagcagaaag
      481 cacttgatgt gcaaacaaga aagcaggcca ataggaagaa agccttactg acgcgtgtcc
      541 aggaaattct tgaaaatgtt caggttagaa aagcgccaaa tgccagtgat tttgatcagt
      601 gggcgacaga aaccattgcc tctaattcag aagtcacagg cttgagtgtc cctgtgacag
      661 ttccaagtga cttgctgagc cccactgaac actgtacttc aggaaagctg ggaaagacaa
      721 ctggactact gccagtgaat aatgaggacc aacaaagccc tgagaggatg ggtctgccta
      781 aagactcaga ggtgtttggt tctctgaagc agtgtgagag tccaggaagc aggtgggcag
      841 aaaatggagc tgctccaagg ctttcttcag caagctcaca agagactgtc atttctgacg
      901 atcccctctt agcaaaggaa gaacaggagc catcatgttt ggctgaagtc actccagatc
      961 cctacataat aagccttcag aatctaatga agaggtcaaa ggaatatgtg gaaagagagc
     1021 aatctagctg gagtctgaga agtagtttaa agaaaagtgt tcatgaaact cattcagaca
     1081 aagaaaacga tgctgctaag gccagtgact gtgtaaagga gaaggctcca cccatgcccg
     1141 taggccggca ctgtggctct gccatccctg acaaaccaag ccttaataag tccaatgtac
     1201 tcctccaagg tgcctctcaa gcaagcagcc tgggcacctc cgttttagct agctttttaa
     1261 aaacagacct acctgtagga actggtcctc ccactgttcc agatgccgag tcagatttta
     1321 aagttattcc tacctttgtt actgaaaata aagttaaaag tcttataggt ccatatgcca
     1381 aattacctag tccagagcca agtatgagtc ctacaatgca tcgaaggcat tcccggtcat
     1441 catcagcatg tcagatcctt ataaacaacc cagtaaatgc ctgtgagcta agcccaaagg
     1501 gaaaagaaga ggcagtagat agaatcgctc cagctgctgc tgaaacaaat gaatctgaaa
     1561 ttgtgccaaa gccaccaact gatttgacag gggttggttc aagcaaggtt tctgctacca
     1621 aagtcatgtc agataccata agagagatgg ttatgggtaa gccaagtcag gtgcatcagg
     1681 ctttaggaaa tcaattaggc aataatgtca ctgttgagca gtttgctatg gaaggtccct
     1741 tcatacctga tggcagggga atgcagaaag tagatggtac ttgtatagct gtgcccaagt
     1801 tgcatgaact gcaacccacc agtcagtgtg tgtcaagtca aaccttggaa gatgcatgtg
     1861 gactcaaggc agccagtgtg ctagcaaaaa actcctgcaa tgtacagatg gaactgaata
     1921 aatcttacga tgtgaaacgc ccatctccct tacttatgca aacccagaat tctagacagc
     1981 agatggacac acctccagtg ccccgcggaa atgaacagtt tgtagataac agttttgaaa
     2041 aagttaagcg gagacttgat ttagatgttg atagtttaca aaaagaaaat tgtccgcata
     2101 ttctgacagc tggatcagct gagcaggaaa gggaacgtcc gccagaaaga agatacccta
     2161 agggatctgt ctatggtaac aagaataaga tgctagaaac tagccctaaa gaaggccagg
     2221 aactactgaa aagcaagatg ttagcttttg aagaaatgcg gaagagacta gaggaacagc
     2281 atgttcagca gttatcactc ctcatagctg agcaggagag ggagcaggaa caacttcaaa
     2341 aggaaataga agagcaggag aagatgctga aagagaaggc agtgacaacg gatgtctctg
     2401 gcttgaacag tgcgctggag ctggagtgga gaaaaagaag cgacccggct ttcctagaaa
     2461 ccatgctgtc ccaagtggac tcgcttcaga cttcaaacaa ctccggcttc ctaagttctg
     2521 ccctgcaata tagctttggc tctgcaagtg aagtaccgct ctacctcagg ggatcactga
     2581 ccagtggcgt gaccaaactc tcagtaacaa ggccttttgg acgggcccaa cctaaatggt
     2641 ctcaggtttt tagtccagaa atacaagcaa aatttaataa aataactgct gtggcaaaag
     2701 ggtttctcac tcgtaaactt atgcaaacag acaaactgaa gcagcttcga caaaccgtaa
     2761 aagacaccat ggaatttata cgaagttttc agtcagaagc ccctctgaag agaggtgtcg
     2821 tctcagccca agatgcttcc cttcaggaac gagtgttagc tcagttgcga gctgccctgt
     2881 atggtattca tgacatcttc ttcgtaatgg atgcagctga gagaatgtca atcctccatc
     2941 atgatcgaga agcccgcaaa gagaagctgc tccggcagat ggataagatg agaagtccac
     3001 gagtggcgct ttcagtggca acacagaagt ccctggacag gaagaagttc atgaaagttg
     3061 ctgaaatggg aatggcaaat aagaagttcc tgcttaagca aaacccttca gaaacaagag
     3121 tccttcagcc aaaccaagga cagaatgcac ctgttcatag gctacttagt agacaaggaa
     3181 cccccaagac atcagtgaag ggggttgtgc aaaatagaca gaagccttca cagagcagag
     3241 tgcctaacag agcgcctgtg tcaggagcat atgcaggaaa aacccaaaga aagcggccaa
     3301 atgttgcgac aatttaagaa gacagcactc gctgggatga agcagggagc agggctgctg
     3361 ccacccacgt tccactctct agtcagggct tttgacttag ccctggactc tttatgcagg
     3421 caaagggaca gcaagggctg agcattggcc tgtctaatct ggtcagcttg gggaattcct
     3481 gcctcatttt cctattaatg ttactttggg taaaaatgat tagtaattgc cttgtttctg
     3541 agcttagcct atataaagat aatttctgtg cccagagtca ccctttttta taaacacgaa
     3601 aagatactta tttttacaaa ttattggaaa gatatcacca attttaaatt agccctaaag
     3661 cctaaatttc attcatgact atgtactaat tgctgaattt ggggaacaaa ttagagacgg
     3721 ttctattcaa agggaaatta ttgcaggaat atctgttttt ctaattttaa acactcagaa
     3781 tcccacatcc tttgacttgc agtgtagcta cacagaatga aacacttcct gctaaatccc
     3841 acataagaag tgactgaggg tcttggtttt gggtagaaaa gaagacattt ctgcagacag
     3901 ctggttgttt tacgggaatg ttgggtttcc tgtgtgttac tgttgggcag atgtagacta
     3961 gattatgtgc actaccctgg gaggtggcac atttagaggc catagcacag ttcatgagca
     4021 cagcacgtgg gtatgcactg tgatggggca gcagagcgca tgcggctagt tctagttagt
     4081 ctgtactagt ctgtgtctgt actagtctgt gtctagttct agttagtcta tactgtttgt
     4141 cttcagtctt ctttttctag catgctttac ataggacaga ataaagggct atttaataag
     4201 aaatccagat ctcagatagc atagtagtaa tactgtctag tttaaaacct gcagtaaagg
     4261 tactcagatt tatggctttc gtgactaaca ttgaaacatc aaccaacaat gtaccaagaa
     4321 aacacgattt tatgaaacag aatgtcactt actatgtaat tccaaaaagg gctttgtgct
     4381 tcttacataa cattgggatt gtgtatattt gaaccatata acttgaattt taaagatagt
     4441 agtattttga agatgcagcc tatatattct taataacctt tttaggaata tggagataaa
     4501 gatggttttt ctgcttttct tccatctgag atttgacttt tatacccagc cagaagttac
     4561 aaaagaatga cccactctgg gtataagctt ggtttccttt attgagactt cccattcact
     4621 gaagagaaga agaagacagg caaaaggtcc aggtcacaga gtttcacccg tagcaaaggt
     4681 gtgccgcagt gttacctgca gtcaccgttc aggtgtaact gtgcttcatc gttccaaacg
     4741 ctcaggactc cgtgtatcat tgtgggctcg gctcttcagt aaggaagagg agctgaaagg
     4801 ctgtgtatgt tagtatgaat tacctaagtg aactatgttt tggaaagtta caaatacttt
     4861 tagattaagg atgagaaact ggagtgtttt taatttcatg gtaaaagttt gcttgtttta
     4921 catttgaatg ttcacagttt tctctcagaa aagtgccaga cactgttttg tgcttttgaa
     4981 gaagttttat ttatatgcat tatttttatt gttattttta ctttgactgg aatgtctatt
     5041 aatgtgaatt gtgtttattt ttatactttg gttttcacta gttttgcttc taggtaaaag
     5101 gcaaaataaa gttttcatcc taaag
//
