LOCUS       NP_001101971            1007 aa            linear   ROD 03-APR-2024
DEFINITION  centriolar coiled-coil protein of 110 kDa [Rattus norvegicus].
ACCESSION   NP_001101971 XP_001078870 XP_341915
VERSION     NP_001101971.1
DBSOURCE    REFSEQ: accession NM_001108501.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 1007)
  AUTHORS   Wang,C., Li,J., Takemaru,K.I., Jiang,X., Xu,G. and Wang,B.
  TITLE     Centrosomal protein Dzip1l binds Cby, promotes ciliary bud
            formation, and acts redundantly with Bromi to regulate ciliogenesis
            in the mouse
  JOURNAL   Development 145 (6) (2018)
   PUBMED   29487109
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 1007)
  AUTHORS   Yadav,S.P., Sharma,N.K., Liu,C., Dong,L., Li,T. and Swaroop,A.
  TITLE     Centrosomal protein CP110 controls maturation of the mother
            centriole during cilia biogenesis
  JOURNAL   Development 143 (9), 1491-1501 (2016)
   PUBMED   26965371
REFERENCE   3  (residues 1 to 1007)
  AUTHORS   Kobayashi,T., Kim,S., Lin,Y.C., Inoue,T. and Dynlacht,B.D.
  TITLE     The CP110-interacting proteins Talpid3 and Cep290 play overlapping
            and distinct roles in cilia assembly
  JOURNAL   J Cell Biol 204 (2), 215-229 (2014)
   PUBMED   24421332
REFERENCE   4  (residues 1 to 1007)
  AUTHORS   Li,J., D'Angiolella,V., Seeley,E.S., Kim,S., Kobayashi,T., Fu,W.,
            Campos,E.I., Pagano,M. and Dynlacht,B.D.
  TITLE     USP33 regulates centrosome biogenesis via deubiquitination of the
            centriolar protein CP110
  JOURNAL   Nature 495 (7440), 255-259 (2013)
   PUBMED   23486064
REFERENCE   5  (residues 1 to 1007)
  AUTHORS   Courtois,A., Schuh,M., Ellenberg,J. and Hiiragi,T.
  TITLE     The transition from meiotic to mitotic spindle assembly is gradual
            during early mammalian development
  JOURNAL   J Cell Biol 198 (3), 357-370 (2012)
   PUBMED   22851319
REFERENCE   6  (residues 1 to 1007)
  AUTHORS   Spektor,A., Tsang,W.Y., Khoo,D. and Dynlacht,B.D.
  TITLE     Cep97 and CP110 suppress a cilia assembly program
  JOURNAL   Cell 130 (4), 678-690 (2007)
   PUBMED   17719545
REFERENCE   7  (residues 1 to 1007)
  AUTHORS   Kleylein-Sohn,J., Westendorf,J., Le Clech,M., Habedanck,R.,
            Stierhof,Y.D. and Nigg,E.A.
  TITLE     Plk4-induced centriole biogenesis in human cells
  JOURNAL   Dev Cell 13 (2), 190-202 (2007)
   PUBMED   17681131
REFERENCE   8  (residues 1 to 1007)
  AUTHORS   Tsang,W.Y., Spektor,A., Luciano,D.J., Indjeian,V.B., Chen,Z.,
            Salisbury,J.L., Sanchez,I. and Dynlacht,B.D.
  TITLE     CP110 cooperates with two calcium-binding proteins to regulate
            cytokinesis and genome stability
  JOURNAL   Mol Biol Cell 17 (8), 3423-3434 (2006)
   PUBMED   16760425
REFERENCE   9  (residues 1 to 1007)
  AUTHORS   Habedanck,R., Stierhof,Y.D., Wilkinson,C.J. and Nigg,E.A.
  TITLE     The Polo kinase Plk4 functions in centriole duplication
  JOURNAL   Nat Cell Biol 7 (11), 1140-1146 (2005)
   PUBMED   16244668
REFERENCE   10 (residues 1 to 1007)
  AUTHORS   Chen,Z., Indjeian,V.B., McManus,M., Wang,L. and Dynlacht,B.D.
  TITLE     CP110, a cell cycle-dependent CDK substrate, regulates centrosome
            duplication in human cells
  JOURNAL   Dev Cell 3 (3), 339-350 (2002)
   PUBMED   12361598
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473956.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_341915.3, XP_001078870.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMD00132262, SAMD00132268
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1007
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q35"
     Protein         1..1007
                     /product="centriolar coiled-coil protein of 110 kDa"
                     /note="centrosomal protein of 110 kDa; centriolar coiled
                     coil protein 110kDa"
                     /calculated_mol_wt=111284
     Region          29..106
                     /region_name="CaM_bind"
                     /note="Calcium-dependent calmodulin binding; pfam16025"
                     /db_xref="CDD:464981"
     CDS             1..1007
                     /gene="Ccp110"
                     /gene_synonym="Cp110; RGD1310509"
                     /coded_by="NM_001108501.1:294..3317"
                     /db_xref="GeneID:361634"
                     /db_xref="RGD:1310509"
ORIGIN      
        1 meeyekfcek alaraqeasl stdsflpaqa esvslirfhg vavlspllti ekrekiqqek
       61 qkaldvqtrk qanrkkallt rvqeilenvq vrkapnasdf dqwatetias nsevtglsvp
      121 vtvpsdllsp tehctsgklg kttgllpvnn edqqspermg lpkdsevfgs lkqcespgsr
      181 waengaaprl ssassqetvi sddpllakee qepsclaevt pdpyiislqn lmkrskeyve
      241 reqsswslrs slkksvheth sdkendaaka sdcvkekapp mpvgrhcgsa ipdkpslnks
      301 nvllqgasqa sslgtsvlas flktdlpvgt gpptvpdaes dfkviptfvt enkvksligp
      361 yaklpspeps msptmhrrhs rsssacqili nnpvnacels pkgkeeavdr iapaaaetne
      421 seivpkpptd ltgvgsskvs atkvmsdtir emvmgkpsqv hqalgnqlgn nvtveqfame
      481 gpfipdgrgm qkvdgtciav pklhelqpts qcvssqtled acglkaasvl aknscnvqme
      541 lnksydvkrp spllmqtqns rqqmdtppvp rgneqfvdns fekvkrrldl dvdslqkenc
      601 philtagsae qererpperr ypkgsvygnk nkmletspke gqellkskml afeemrkrle
      661 eqhvqqlsll iaeqereqeq lqkeieeqek mlkekavttd vsglnsalel ewrkrsdpaf
      721 letmlsqvds lqtsnnsgfl ssalqysfgs asevplylrg sltsgvtkls vtrpfgraqp
      781 kwsqvfspei qakfnkitav akgfltrklm qtdklkqlrq tvkdtmefir sfqseaplkr
      841 gvvsaqdasl qervlaqlra alygihdiff vmdaaermsi lhhdrearke kllrqmdkmr
      901 sprvalsvat qksldrkkfm kvaemgmank kfllkqnpse trvlqpnqgq napvhrllsr
      961 qgtpktsvkg vvqnrqkpsq srvpnrapvs gayagktqrk rpnvati
//
