LOCUS       NM_001401305            2228 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cyclin L2 (Ccnl2), transcript variant 1, mRNA.
ACCESSION   NM_001401305 XM_006239545
VERSION     NM_001401305.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2228)
  AUTHORS   Herrmann,A., Fleischer,K., Czajkowska,H., Muller-Newen,G. and
            Becker,W.
  TITLE     Characterization of cyclin L1 as an immobile component of the
            splicing factor compartment
  JOURNAL   FASEB J 21 (12), 3142-3152 (2007)
   PUBMED   17494991
REFERENCE   2  (bases 1 to 2228)
  AUTHORS   Chen,H.H., Wang,Y.C. and Fann,M.J.
  TITLE     Identification and characterization of the CDK12/cyclin L1 complex
            involved in alternative splicing regulation
  JOURNAL   Mol Cell Biol 26 (7), 2736-2745 (2006)
   PUBMED   16537916
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Jan 3, 2023 this sequence version replaced NM_001401305.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.314906.1,
                                           SRR26643293.31968.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-296               JAXUCZ010000005.1  171699775-171700070
            297-371             JAXUCZ010000005.1  171700478-171700552
            372-481             JAXUCZ010000005.1  171700765-171700874
            482-602             JAXUCZ010000005.1  171702683-171702803
            603-667             JAXUCZ010000005.1  171705197-171705261
            668-767             JAXUCZ010000005.1  171707615-171707714
            768-872             JAXUCZ010000005.1  171708072-171708176
            873-1020            JAXUCZ010000005.1  171708262-171708409
            1021-1129           JAXUCZ010000005.1  171708855-171708963
            1130-1222           JAXUCZ010000005.1  171709045-171709137
            1223-2228           JAXUCZ010000005.1  171710032-171711037
FEATURES             Location/Qualifiers
     source          1..2228
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2228
                     /gene="Ccnl2"
                     /note="cyclin L2"
                     /db_xref="GeneID:298686"
                     /db_xref="RGD:1309149"
     exon            1..296
                     /gene="Ccnl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             15..1577
                     /gene="Ccnl2"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="cyclin-L2 isoform 1"
                     /protein_id="NP_001388234.1"
                     /db_xref="GeneID:298686"
                     /db_xref="RGD:1309149"
                     /translation="MAAAAAGASGLMAPALAACSSGSGGAAPGSQGVLIGDRLYSGVL
                     ITLENCLLPDDKLRFTPSMSSGLDIDTETGLRVVGCELIQAAGILLRLPQVAMATGQV
                     LFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRHLREKKKPVP
                     LVLDQEYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTAW
                     NYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICF
                     KILQLYTRKKVDLTHLESEVEKRKHAIEEAKARAKGLLPPGSAPGLDSATAGFSPAPK
                     PESPKEGKGSKSSPLSVKNAKRKMEGPKKAKGDSPVNGLLKGQESRSQSRSREQSYSR
                     SPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQVHRGAPYKGSEVRGSRKSKD
                     CKHLTQKPHKSRSRSSSRSRSRSRERTDSSGKYKKKSHYYRDQRRERSRSYERTGHRY
                     ERDHPGHSRHRR"
     exon            297..371
                     /gene="Ccnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            372..481
                     /gene="Ccnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            482..602
                     /gene="Ccnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            603..667
                     /gene="Ccnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            668..767
                     /gene="Ccnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            768..872
                     /gene="Ccnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            873..1020
                     /gene="Ccnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1129
                     /gene="Ccnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1222
                     /gene="Ccnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..2228
                     /gene="Ccnl2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcggcggca caaaatggcg gcggcggcag ccggggcttc ggggttgatg gctcctgcgt
       61 tggcggcctg ctcttccggc tcggggggag cagccccagg gtctcagggg gtgctgatcg
      121 gtgacaggct atactccgga gttctcatca ccttggaaaa ctgcctgctg cccgacgaca
      181 agctccgctt cacgccatcc atgtcgagcg gtctcgacat cgatacagag actggactcc
      241 gcgtagtggg ctgcgagctc atccaggcag ccggcatcct actccgcctg ccgcaggtgg
      301 ccatggctac agggcaggtg ttgttccagc gcttctttta cactaagtcc ttcgtgaaac
      361 attccatgga gcatgtgtcc atggcttgtg ttcacctggc ttccaaaata gaagaggctc
      421 caagacgaat cagagatgtc atcaacgtat tccatcgcct tcggcatctg cgagagaaaa
      481 agaaacctgt gcctctggtg ctggatcaag agtatgttaa tctgaagaac cagattataa
      541 aggcagagag acgggttctc aaggaattgg gcttttgtgt ccatgtgaag catcctcaca
      601 agataatcgt tatgtacctt caggtgttag aatgtgagcg taatcagcac ctggtccaga
      661 ctgcatggaa ctacatgaat gacagccttc gcacagatgt ctttgtgcgg ttccagcctg
      721 aaagcattgc ttgtgcctgt atctaccttg ctgcccggac actggagatc cctttaccta
      781 atcgtccaca ttggtttctt ttgtttggag caactgaaga ggaaattcaa gaaatttgct
      841 ttaaaatctt gcagctttat acacggaaaa aggttgactt gacgcatctg gaaagtgaag
      901 tggaaaagag aaagcacgcc atcgaagagg caaaggcacg agccaagggt ctgctgccac
      961 cagggagtgc gccaggcttg gacagtgcta ctgcagggtt ctcacccgct cccaagccgg
     1021 aatcccccaa agaaggtaaa ggaagcaagt cttccccact ctctgtaaag aatgccaaac
     1081 ggaaaatgga aggcccaaag aaagccaagg gcgacagccc tgtaaatggc ttgctaaaag
     1141 ggcaggagag tcgaagtcaa agcaggagtc gtgagcagag ctactcaagg tccccatcac
     1201 ggtctgcttc tccaaagaga aggaaaagtg atagtggctc tacctcaggg gggtccaagt
     1261 cacagagtcg ttctcggagc cgcagtgact ctcctccaag gcaagtacac cgtggtgctc
     1321 cctacaaagg ctcagaagtg aggggctccc ggaaatccaa ggactgcaag cacctcaccc
     1381 agaagccaca caagtctcgt agccggagct cctcccgttc ccgcagccgg tcacgagaac
     1441 ggacagacag ttctggaaaa tacaagaaga aaagtcatta ctatagagat caaagacggg
     1501 agcgctcaag gtcatatgag cgcacaggcc atcgatatga gagggaccac cctggacaca
     1561 gcaggcatcg gaggtgagat aggttccctg gtggctgccc ttggtccctc cctgttgggc
     1621 acaccttggc ttcagtggcc ttgtcacata atgttttttt aaagtgtttt tgattggacc
     1681 ttgaggtgaa tttgacagtg ggcaaggtgc ccttcaggct ggcctgggga gtgctgcaca
     1741 tctgtcctag gtaatggtcc acctcaactg cagaccttca ggtagctgga tggaacagca
     1801 aaggcacacg cctccactgg cgtggcttgg tgctattgac aagctgtctc ttcactccta
     1861 aactgatact caattacgtt aagccaagaa agatgatttt tcaaatcttt gcctatatta
     1921 ggttgtactt gtgtacatat tttgcagtgg ttcacaatga gaaaatggcc ttaatagccc
     1981 ccttgttctc tattcacgtt gtaaataaac atgtttaata caagtgaaag ctatatatga
     2041 gaactcagaa tttgattctg ttagcttaac acttgtatag aaaattgaga tttttaaaat
     2101 gtgaaggtat ttaggtctgt gttgaaagtc atatattttt atctgtgcaa tgctgagtgc
     2161 aggccaccag ctcgagagaa attttacgtg gttgaataaa caattctcag gacacttgtt
     2221 atgtaaga
//
