LOCUS       NM_001100474            3313 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus cyclin F (Ccnf), mRNA.
ACCESSION   NM_001100474 XM_001054372 XM_340763
VERSION     NM_001100474.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3313)
  AUTHORS   D'Angiolella,V., Donato,V., Vijayakumar,S., Saraf,A., Florens,L.,
            Washburn,M.P., Dynlacht,B. and Pagano,M.
  TITLE     SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity
            through CP110 degradation
  JOURNAL   Nature 466 (7302), 138-142 (2010)
   PUBMED   20596027
REFERENCE   2  (bases 1 to 3313)
  AUTHORS   Ebstein,F., Lange,N., Urban,S., Seifert,U., Kruger,E. and
            Kloetzel,P.M.
  TITLE     Maturation of human dendritic cells is accompanied by functional
            remodelling of the ubiquitin-proteasome system
  JOURNAL   Int J Biochem Cell Biol 41 (5), 1205-1215 (2009)
   PUBMED   19028597
REFERENCE   3  (bases 1 to 3313)
  AUTHORS   Tetzlaff,M.T., Bai,C., Finegold,M., Wilson,J., Harper,J.W.,
            Mahon,K.A. and Elledge,S.J.
  TITLE     Cyclin F disruption compromises placental development and affects
            normal cell cycle execution
  JOURNAL   Mol Cell Biol 24 (6), 2487-2498 (2004)
   PUBMED   14993286
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On or before Oct 14, 2007 this sequence version replaced
            XM_001054372.1, XM_340763.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF410816.1, SRR26643292.39421.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-47                JAXUCZ010000010.1  13783623-13783669   c
            48-202              JAXUCZ010000010.1  13781445-13781599   c
            203-309             JAXUCZ010000010.1  13777878-13777984   c
            310-377             JAXUCZ010000010.1  13776682-13776749   c
            378-571             JAXUCZ010000010.1  13775386-13775579   c
            572-625             JAXUCZ010000010.1  13774496-13774549   c
            626-730             JAXUCZ010000010.1  13773877-13773981   c
            731-808             JAXUCZ010000010.1  13773482-13773559   c
            809-960             JAXUCZ010000010.1  13771223-13771374   c
            961-1125            JAXUCZ010000010.1  13768344-13768508   c
            1126-1249           JAXUCZ010000010.1  13766773-13766896   c
            1250-1430           JAXUCZ010000010.1  13766325-13766505   c
            1431-1518           JAXUCZ010000010.1  13765699-13765786   c
            1519-1618           JAXUCZ010000010.1  13762145-13762244   c
            1619-1746           JAXUCZ010000010.1  13761936-13762063   c
            1747-1916           JAXUCZ010000010.1  13760416-13760585   c
            1917-3313           JAXUCZ010000010.1  13758421-13759817   c
FEATURES             Location/Qualifiers
     source          1..3313
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..3313
                     /gene="Ccnf"
                     /note="cyclin F"
                     /db_xref="GeneID:117524"
                     /db_xref="RGD:67401"
     exon            1..47
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..2374
                     /gene="Ccnf"
                     /codon_start=1
                     /product="cyclin-F"
                     /protein_id="NP_001093944.1"
                     /db_xref="GeneID:117524"
                     /db_xref="RGD:67401"
                     /translation="MGSGGVIHCRCAKCFCYPTKRRIKRRPRNLTILSLPEDVLFHIL
                     KWLSVGDILAVRAVHSHLKYLVDNHASVWASASFQELWPSPQNLKLFERAAEKGNFEA
                     AVKLGIAYLYNEGLSVSDEACAEVNGLKASRFFSMAERLNTGSDPFIWLFIRPPWSVS
                     GSCCKAVVHDSLRAECQLQRSHKASILHCLGRVLNLFEDEEKRKQAHNLFEESAHQGC
                     LASSYLLWESDRKVDMSDPGRCLHSFRKLRDYAAKGCWEAQLALAKACAGGSQLGLEG
                     KACSESVCQLFQASQAVNKQQIFSVQKGLSDTMRYILIDWLVEVATMKDFTSLCLHLT
                     VECVDRYLRRRLVPRYKLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVR
                     VMGEIISALEGKIRIPTVVDYKEVLLTLVPVAPRTQHLCSFLCELTLLHTSLSVYAPA
                     RLASAALLLARLMHGHTQPWTTQLWDLTGFSYSDLTPCVLSLHKKCFHDDAPKDYRQV
                     SLTAVKQRFEDKCYEEISQEEVLSYAELCSALGVKQESPEPPSFPSSGEIHTFLSSPS
                     GRRSKRKRENSLQEDRGSFVTTPTAELSNQEETLLGSLLDWSLDCCSGYEGDQESEGE
                     KEGDVTAPSGLLDVTVVYLNPEEHCCQESSDEEVWPEDKSHPTPGTQAPPASAPWPLP
                     CNRGDPGKDVTTSGYSSVSSSSPISSLDGGMVGSPRSTSVLSVGSHSSTKPCYHQAKK
                     SCLQCRPPNPPESGAHQQPVKRQNLSVHSDEDTNLGFLKL"
     exon            48..202
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            203..309
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            310..377
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            378..571
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            572..625
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            626..730
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            731..808
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            809..960
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1125
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            1126..1249
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1430
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1518
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1618
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            1619..1746
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            1747..1916
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
     exon            1917..3313
                     /gene="Ccnf"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtctaaggc ggcagtggtg ggagctcggc gatggggagc ggcggtgtga tccactgtag
       61 gtgtgccaag tgtttctgtt atcctacgaa gcgaagaatc aaaagaagac ccaggaactt
      121 gaccatcttg agtctcccag aagacgtgct ctttcatatc ctgaaatggc tttctgttgg
      181 agacatcctg gctgtccgag ctgttcactc ccacctcaag tacctggtgg acaaccatgc
      241 cagtgtgtgg gcatctgcca gcttccaaga gctgtggcct tctccacaga acctaaagct
      301 gtttgaaagg gctgccgaaa aggggaattt tgaagctgct gtgaagttgg gcatcgccta
      361 cctctacaat gaaggcttgt ctgtgtcgga tgaggcctgc gcagaagtga acggcctgaa
      421 ggcctctcgc ttcttcagca tggccgagag attgaatacg ggttcggacc ccttcatctg
      481 gctcttcatc cgcccgccgt ggtcagtgtc tggaagctgt tgcaaggccg tggtccatga
      541 cagcctcagg gctgagtgtc agttacaaag aagtcataaa gcttccatac tgcactgctt
      601 gggaagagtg ctgaatcttt ttgaggacga agagaaaagg aagcaggctc ataacctttt
      661 tgaagaatct gctcatcagg gatgcttggc cagctcatac ctcctttggg aaagtgacag
      721 aaaggtggat atgtctgacc ccggacgatg cctccacagc ttccggaaac tcagggacta
      781 cgccgccaag ggctgctggg aagcacagct ggctttggcc aaagcctgcg caggaggaag
      841 ccagcttgga ctagaaggga aggcctgcag tgagtcagtc tgccagctct tccaagcctc
      901 ccaggccgtc aacaagcagc agatattctc tgtgcagaag gggctcagtg acaccatgag
      961 gtacattcta atcgactggt tggtggaagt tgccaccatg aaggacttca caagcctgtg
     1021 tctccacctg acagtggagt gtgtagaccg gtacttgcgg agaagactgg tccccagata
     1081 caagctccag cttctgggca tcgcctgcat ggtcatctgt acccggttca tcagcaaaga
     1141 gattctgacc attagagagg ctgtgtggct cacagacaac acgtataaat acgaggactt
     1201 ggtacgcgtg atgggggaga tcatctccgc cctggaaggg aagattcgga tccctacggt
     1261 ggttgactat aaagaggtcc tgctgacact ggtccctgtc gcacccagaa cccaacacct
     1321 gtgcagcttc ctctgtgagc tcaccctgct gcacaccagc ctgtccgtct acgccccagc
     1381 ccgcctggcc tctgccgccc tgctcctggc cagactgatg catggacaca cacagccctg
     1441 gaccactcag ctgtgggacc tcactgggtt ctcctacagc gacctcacgc cctgcgtctt
     1501 gagcctccat aagaagtgtt tccatgatga tgcacccaaa gactacagac aagtctctct
     1561 gacggccgtg aagcagcggt ttgaggataa gtgctatgag gagatcagcc aggaagaggt
     1621 actgagctat gccgaactgt gcagtgcatt aggggtgaaa caggagagcc cagagccccc
     1681 gtctttccct agctccgggg agatccacac cttcctcagc tcaccctctg ggaggagaag
     1741 caaacggaag cgagagaaca gccttcagga ggacagggga agctttgtta ccacacccac
     1801 cgcagaacta tcgaaccagg aggagacatt gctaggcagc cttctggact ggagcctgga
     1861 ctgctgctct ggctatgagg gagaccagga gagcgaagga gagaaggagg gggatgttac
     1921 agctcccagt ggactccttg acgtcactgt ggtctacctg aacccagaag aacactgctg
     1981 ccaggagtcc agtgatgagg aggtgtggcc agaggacaag agccacccaa caccaggcac
     2041 ccaggcacct ccagcctcag ctccctggcc ccttccctgc aacaggggag atccgggcaa
     2101 ggatgtcacg acctcaggct actcctctgt cagcagctca agtcccataa gctccctgga
     2161 tggtggcatg gtgggctctc cccgatctac ctcagtgctc tctgtgggaa gccactcaag
     2221 cacaaagcct tgctaccatc aggccaagaa gtcatgttta cagtgtcgtc ccccaaatcc
     2281 cccagagagc ggtgctcacc agcaaccggt aaagcgccaa aacctgtcgg tgcacagtga
     2341 cgaggacacg aacctgggct tcctgaagct ctgagtgtgc taagccttcg ccacgctgaa
     2401 tgtttactga gggagggccg ctgtttcact aggacactgc cgatgggtgc tgtgtagatc
     2461 cagaagggca acagattcct taggggagtt cagtgcaagc tgtcagaaca tcgagctagg
     2521 tgaaaaagct caacctctac atgctggaca gcagcctccc ggcagtcctg gcacacctgt
     2581 gaaacccatc cctctctacc cttctgtgtc ctgctgtcgg gaagcatgag cctccatgtt
     2641 gggattcact atctgaggcc aggagctgac aacctccttg gaatactagc ctgggtaacc
     2701 taacacagtt caaacccctg ccagcaagtc ttgttttaga ccagtgggga gctctcaact
     2761 gaacacagca ctgtcccccc tcaccccttc agcctaggga gcctgtgtcc ctgcatatca
     2821 gtgttgactc tcgcctaatg gtgaggtgtg aggcccttga agctggggtc acaggcgtcc
     2881 ctgtccctcc ctctggcact ttgagctcat tttcaaaatc tgtcctcccg gagtggtttg
     2941 tctgtgtccc atcgtatcca tgtgaccgac cgtgtttctg cactgaattt ctaggccatt
     3001 ctttgcccgt ctttatttct acgtttcttc taatggggag gaaaaaaaaa agaggaagct
     3061 attgaaatag aagtattaaa taaaaagata acagatcccc aatatcactg agcttcaact
     3121 gaaaagtgaa aatctagtcc tgcatggtgg cccgacactg cagtcccagc agccagaagt
     3181 atggcaagag gaccagaagc tccaggtcag cctgggctgg gtcatgtgac ctcaggaaaa
     3241 ggaaactgat gaccgcccct tggttctagc ctcatgttct ctccttatga aaaatgaatc
     3301 tttctagagt ata
//
