LOCUS       NM_001009470            1520 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cyclin B2 (Ccnb2), mRNA.
ACCESSION   NM_001009470 XM_343419
VERSION     NM_001009470.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1520)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1520)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   3  (bases 1 to 1520)
  AUTHORS   Nishihara,K., Masuda,S., Nakagawa,S., Yonezawa,A., Ichimura,T.,
            Bonventre,J.V. and Inui,K.
  TITLE     Impact of Cyclin B2 and Cell division cycle 2 on tubular
            hyperplasia in progressive chronic renal failure rats
  JOURNAL   Am J Physiol Renal Physiol 298 (4), F923-F934 (2010)
   PUBMED   20071461
  REMARK    GeneRIF: These results advance the knowledge of cell cycle
            regulators effects in tubular restoration and/or degeneration, and
            the cyclin b2 and CDC2 molecules are suggested to be a marker for
            the proliferation of proximal tubular cells in kidney failure.
REFERENCE   4  (bases 1 to 1520)
  AUTHORS   Kuroda,T., Naito,K., Sugiura,K., Yamashita,M., Takakura,I. and
            Tojo,H.
  TITLE     Analysis of the roles of cyclin B1 and cyclin B2 in porcine oocyte
            maturation by inhibiting synthesis with antisense RNA injection
  JOURNAL   Biol Reprod 70 (1), 154-159 (2004)
   PUBMED   12954723
REFERENCE   5  (bases 1 to 1520)
  AUTHORS   Brandeis,M., Rosewell,I., Carrington,M., Crompton,T., Jacobs,M.A.,
            Kirk,J., Gannon,J. and Hunt,T.
  TITLE     Cyclin B2-null mice develop normally and are fertile whereas cyclin
            B1-null mice die in utero
  JOURNAL   Proc Natl Acad Sci U S A 95 (8), 4344-4349 (1998)
   PUBMED   9539739
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088212.1.
            
            On Jan 7, 2005 this sequence version replaced XM_343419.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088212.1, BC097952.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1520
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..1520
                     /gene="Ccnb2"
                     /note="cyclin B2"
                     /db_xref="GeneID:363088"
                     /db_xref="RGD:1308176"
     exon            1..92
                     /gene="Ccnb2"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1265
                     /gene="Ccnb2"
                     /codon_start=1
                     /product="G2/mitotic-specific cyclin-B2"
                     /protein_id="NP_001009470.1"
                     /db_xref="GeneID:363088"
                     /db_xref="RGD:1308176"
                     /translation="MALLRRPTVSSDLKNIDTGVNPKAKSHVTVRRAVLEEIGNKVRA
                     RPAQVAKKPQNTKVPVQPTKAINASKQPKPTASVKPVQMETLAPKDPLPAPEDVSMKE
                     ESLCQAFSDALLCKIEDIDNEDGENPQLCSDYVKDIYQYLRQLEALQSINPHFLDGRD
                     INGRMRAILVDWLVQVHSKFRLLQETLYMCIAIMDRFLQAQPVCRKKLQLVGITALLL
                     ASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKA
                     GEVDVEQHTLAKYLMELTLVDYDMVHYHPSQVAAAASCLSQKVLGQGKWNLKQQYYTG
                     YMESEILEVMQHMAKNVVKVNENLTKFIAVKNKYASSRLLKISTIPQLNSRTIKDLAS
                     PLMGRP"
     exon            93..221
                     /gene="Ccnb2"
                     /inference="alignment:Splign:2.1.0"
     exon            222..335
                     /gene="Ccnb2"
                     /inference="alignment:Splign:2.1.0"
     exon            336..506
                     /gene="Ccnb2"
                     /inference="alignment:Splign:2.1.0"
     exon            507..665
                     /gene="Ccnb2"
                     /inference="alignment:Splign:2.1.0"
     exon            666..902
                     /gene="Ccnb2"
                     /inference="alignment:Splign:2.1.0"
     exon            903..1043
                     /gene="Ccnb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1154
                     /gene="Ccnb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1155..1488
                     /gene="Ccnb2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgagactcc caacggtgtc gcggatcgga gtggcagtgc ctcgtccgca cttgccagag
       61 cggccctcat ggcgctgctc cgacgcccga cggtgtccag tgatttgaag aatattgaca
      121 caggagttaa tcctaaagct aagagccatg tgactgtccg gcgagctgtt ttagaagaaa
      181 ttggaaataa agttagagcc agaccggctc aagtggctaa gaaacctcag aataccaaag
      241 taccagtcca gcccaccaaa gcaataaatg ccagcaaaca gccgaaacct acagcttctg
      301 tgaaaccagt gcagatggag acactggccc cgaaggatcc tctgcctgcc cctgaggatg
      361 tctccatgaa ggaagagagc ctctgccaag ctttctctga tgctttgctc tgcaagattg
      421 aggacataga taatgaggac ggggagaacc ctcagctctg cagtgactac gtgaaggaca
      481 tctaccagta cctcaggcag cttgaggctt tgcagtccat caatccacat ttcttagatg
      541 gaagagacat aaacggacgc atgcgtgcca tcctggtgga ctggctggtc caagtccatt
      601 ccaagtttag gcttctgcag gagactctgt acatgtgcat tgctatcatg gaccggttcc
      661 ttcaggctca gccagtctgc cggaagaagc tgcaactggt tgggatcaca gctctgctct
      721 tggcttccaa atatgaggag atgttttctc caaatatcga agactttgtt tatatcacag
      781 ataatgctta caccagttcc caaatccgag aaatggagac tctgattttg aaagagttga
      841 aattcgagtt gggccggcct ttgccactcc acttcctaag gcgagcctca aaagccgggg
      901 aggtggatgt tgaacagcac acgttagcca agtacctgat ggagctgacc ctcgtcgact
      961 acgacatggt gcattaccac ccttctcagg tcgcagctgc tgcttcctgc ctctctcaga
     1021 aggtgctggg ccaaggaaaa tggaatttaa agcagcagta ttacacaggc tacatggaga
     1081 gtgaaatact ggaagtcatg cagcacatgg ccaagaacgt cgtgaaagtc aatgaaaacc
     1141 tcaccaagtt catcgctgtc aagaacaaat atgccagcag caggctcctg aagatcagca
     1201 cgatccctca gctgaactcc agaaccatca aagacctggc ctcccctctg atgggcagac
     1261 cctaggcagc cgggcttcct tccatcgtgt gcttctcaga tttgtatata ttctagttta
     1321 catcacaaaa cctaattttc taattgtgta ttgatgaaaa ataaagctat tgattttctt
     1381 aaggtacccg tgtatatctg tatgctctat actgaagaaa tgtagaatgg cctaccataa
     1441 ccgtgctctg tactgaagaa aaataaagcc actgatttac ttaaggtaaa aaaaaaaaaa
     1501 aaaaaaaaaa aaaaaaaaaa
//
