LOCUS       NM_001025141            1817 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus cyclin B1 interacting protein 1 (Ccnb1ip1), mRNA.
ACCESSION   NM_001025141 XM_573753 XM_573754
VERSION     NM_001025141.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1817)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1817)
  AUTHORS   Holloway,J.K., Sun,X., Yokoo,R., Villeneuve,A.M. and Cohen,P.E.
  TITLE     Mammalian CNTD1 is critical for meiotic crossover maturation and
            deselection of excess precrossover sites
  JOURNAL   J Cell Biol 205 (5), 633-641 (2014)
   PUBMED   24891606
REFERENCE   3  (bases 1 to 1817)
  AUTHORS   Qiao,H., Prasada Rao,H.B., Yang,Y., Fong,J.H., Cloutier,J.M.,
            Deacon,D.C., Nagel,K.E., Swartz,R.K., Strong,E., Holloway,J.K.,
            Cohen,P.E., Schimenti,J., Ward,J. and Hunter,N.
  TITLE     Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212
            regulate meiotic recombination
  JOURNAL   Nat Genet 46 (2), 194-199 (2014)
   PUBMED   24390283
REFERENCE   4  (bases 1 to 1817)
  AUTHORS   Ward,J.O., Reinholdt,L.G., Motley,W.W., Niswander,L.M.,
            Deacon,D.C., Griffin,L.B., Langlais,K.K., Backus,V.L.,
            Schimenti,K.J., O'Brien,M.J., Eppig,J.J. and Schimenti,J.C.
  TITLE     Mutation in mouse hei10, an e3 ubiquitin ligase, disrupts meiotic
            crossing over
  JOURNAL   PLoS Genet 3 (8), e139 (2007)
   PUBMED   17784788
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC091423.1.
            
            On or before Jul 1, 2005 this sequence version replaced
            XM_573753.1, XM_573754.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091423.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..1817
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p14"
     gene            1..1817
                     /gene="Ccnb1ip1"
                     /note="cyclin B1 interacting protein 1"
                     /db_xref="GeneID:498492"
                     /db_xref="RGD:1561930"
     exon            1..9
                     /gene="Ccnb1ip1"
                     /inference="alignment:Splign:2.1.0"
     exon            10..183
                     /gene="Ccnb1ip1"
                     /inference="alignment:Splign:2.1.0"
     exon            184..256
                     /gene="Ccnb1ip1"
                     /inference="alignment:Splign:2.1.0"
     exon            257..392
                     /gene="Ccnb1ip1"
                     /inference="alignment:Splign:2.1.0"
     exon            393..709
                     /gene="Ccnb1ip1"
                     /inference="alignment:Splign:2.1.0"
     CDS             413..1243
                     /gene="Ccnb1ip1"
                     /EC_number="2.3.2.27"
                     /note="cyclin B1 interacting protein 1, E3 ubiquitin
                     protein ligase"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase CCNB1IP1"
                     /protein_id="NP_001020312.1"
                     /db_xref="GeneID:498492"
                     /db_xref="RGD:1561930"
                     /translation="MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSHS
                     PAICPACNSTLSGKLDIVRTELSPSEEYKAMVLAGLRPEVVLDISSRALAFWTYQVHQ
                     ERLYQEYNFSKAENHLKQMEKIYTQQIQSKDVELTSMKGEVTSMKKVLEEYKKKFSDI
                     SEKLMERNRQYQKLQGLYDSLRLRNITIASQEGSLEPAMIPQSGVFGFPSGNSSKFSL
                     DHTPAGNQGGGDEDVQFRPFFVCSPTAPEPVNNFFSFASQSHEAEQQVCSRAFKAKRI
                     "
     exon            710..1043
                     /gene="Ccnb1ip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1791
                     /gene="Ccnb1ip1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1768..1773
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccnb1ip1"
     polyA_site      1791
                     /gene="Ccnb1ip1"
ORIGIN      
        1 ggtggtctgt ttcaggttga agatgaaacg tatccaggaa agagctggga ctgtagcact
       61 cagcccagtg gctgagtcca gcccagcaca ggcccagagg ccctgcacaa cccccagaat
      121 atctctaaag tgggcttgga tattctcaag aaggtttaaa ggctgatggc actgtaaatg
      181 cagatgagat ggcagcccgt ttgctctggt atttccactt ggattcctag gttaagctgg
      241 atgcatttgt taacagaaat gaggggtaaa acccaagaag tacaaatgtt caacagtcag
      301 gagagaacac caggttgaca gcatcacatt tcctgtctgg accttcatgc tataaaccag
      361 ttgtatgaaa aaaatgatcg catggtttaa tggattcttt gggacactcg tcatgtcttt
      421 gtgtgaagac atgttgctgt gcaattatcg gaagtgtcgt atcaagctct ctggctatgc
      481 ttgggtcacg gcctgctctc acatcttctg tgatcagcat ggcagtggtg agttcagtca
      541 ttcaccagca atctgccctg cttgcaacag caccctttct ggaaagctag acattgtccg
      601 gacagagctc agtccgtcag aggagtacaa agctatggta ttggcagggc ttcgacccga
      661 ggttgttttg gacattagct cccgagcatt ggccttctgg acgtaccagg tgcaccagga
      721 acgtctctat caagaataca atttcagcaa ggctgagaac cacttaaaac agatggagaa
      781 gatatacacg cagcaaatac agagcaagga cgtagaattg acctctatga aaggggaggt
      841 tacctccatg aagaaagttc tggaggaata caagaagaag tttagtgata tctctgagaa
      901 actgatggag cgcaaccgcc aataccaaaa gctccaaggc ctttatgata gcctcaggct
      961 aaggaatatc actatcgcta gccaggaggg ctccctggaa ccagctatga tcccacagtc
     1021 tggagtcttt ggcttcccat cagggaatag ctcaaagttt tctttggacc atacaccagc
     1081 tggaaatcaa ggtggtggag atgaagatgt tcagttcaga ccattttttg tgtgttctcc
     1141 cacagcacct gaacctgtta acaacttctt tagttttgcg tctcaaagcc atgaagcaga
     1201 gcagcaagtc tgcagcaggg cctttaaagc aaaaagaatt tagctcattt tttatttcaa
     1261 gactgttttc ctgcatccct gggttctctt cacatgtcgg ccttagaaga agttggcttg
     1321 cagtcggtat gtggcttcct gtttggtttt ttcactgttt gcttagggca cgggcatttc
     1381 atgaatgtca gtctctagtt tgccattgct cacacagtca cactgctgca cagatcgtgt
     1441 ttcagaccaa gctgtgttta tgtttatgta gccaccaatg ttgtatttac atggcgcttt
     1501 ggattccagt gtgtgtatgt tgagtgtgtg cattgattct tctgccagta tatttctgta
     1561 aaaattatgg tcttggaaaa tgatggccaa aataatggtc ttagaaaatg gtggcttgca
     1621 attaacatgt actttacagt catgtatttt ggaggtgtgc ttatgccagt ggctggaagt
     1681 gcaatttgat gcatatgtgt tctgtttatc tttaaaaaaa tttatactga taaaattatt
     1741 tgttgatttc attggtattt gttttaaaat aaaactgctt taccttttaa aaaaaaaaaa
     1801 aaaaaaaaaa aaaaaaa
//
