LOCUS       NM_001007612             807 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus C-C motif chemokine ligand 7 (Ccl7), mRNA.
ACCESSION   NM_001007612 XM_213419
VERSION     NM_001007612.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 807)
  AUTHORS   Mao,D., Jiang,H., Zhang,F., Yang,H., Fang,X., Zhang,Q. and Zhao,G.
  TITLE     HDAC2 exacerbates rheumatoid arthritis progression via the
            IL-17-CCL7 signaling pathway
  JOURNAL   Environ Toxicol 38 (7), 1743-1755 (2023)
   PUBMED   37021908
  REMARK    GeneRIF: HDAC2 exacerbates rheumatoid arthritis progression via the
            IL-17-CCL7 signaling pathway.
REFERENCE   2  (bases 1 to 807)
  AUTHORS   Shi,G., Zhang,Z., Ma,S., Li,Y., Du,S., Chu,Y., Li,Y., Tang,X.,
            Yang,Y., Chen,Z., Wang,Z. and Wu,H.
  TITLE     Hepatic interferon regulatory factor 8 expression mediates liver
            ischemia/reperfusion injury in mice
  JOURNAL   Biochem Pharmacol 192, 114728 (2021)
   PUBMED   34400126
REFERENCE   3  (bases 1 to 807)
  AUTHORS   Yang,Y., Shen,C., Li,J., Yuan,J., Wei,J., Huang,F., Wang,F., Li,G.,
            Li,Y., Xing,L., Peng,L., Yang,M., Cao,M., Zheng,H., Wu,W., Zou,R.,
            Li,D., Xu,Z., Wang,H., Zhang,M., Zhang,Z., Gao,G.F., Jiang,C.,
            Liu,L. and Liu,Y.
  TITLE     Plasma IP-10 and MCP-3 levels are highly associated with disease
            severity and predict the progression of COVID-19
  JOURNAL   J Allergy Clin Immunol 146 (1), 119-127 (2020)
   PUBMED   32360286
REFERENCE   4  (bases 1 to 807)
  AUTHORS   Ke,B.C., Huang,X.X., Li,Y., Li,L.Y., Xu,Q.X., Gao,Y., Liu,Y. and
            Luo,J.
  TITLE     Neuronal-derived Ccl7 drives neuropathic pain by promoting
            astrocyte proliferation
  JOURNAL   Neuroreport 27 (11), 849-857 (2016)
   PUBMED   27295026
  REMARK    GeneRIF: This study demonstrated that that Ccl7 promoted astrocyte
            proliferation and thus contributed toward neuropathic pain.
REFERENCE   5  (bases 1 to 807)
  AUTHORS   Patsouras,M.D., Sikara,M.P., Grika,E.P., Moutsopoulos,H.M.,
            Tzioufas,A.G. and Vlachoyiannopoulos,P.G.
  TITLE     Elevated expression of platelet-derived chemokines in patients with
            antiphospholipid syndrome
  JOURNAL   J Autoimmun 65, 30-37 (2015)
   PUBMED   26283469
REFERENCE   6  (bases 1 to 807)
  AUTHORS   Sabroe,I., Hartnell,A., Jopling,L.A., Bel,S., Ponath,P.D.,
            Pease,J.E., Collins,P.D. and Williams,T.J.
  TITLE     Differential regulation of eosinophil chemokine signaling via CCR3
            and non-CCR3 pathways
  JOURNAL   J Immunol 162 (5), 2946-2955 (1999)
   PUBMED   10072545
REFERENCE   7  (bases 1 to 807)
  AUTHORS   Wright,E.D., Frenkiel,S., Ghaffar,O., al-Ghamdi,K., Luster,A.,
            Miotto,D. and Hamid,Q.
  TITLE     Monocyte chemotactic protein expression in allergy and
            non-allergy-associated chronic sinusitis
  JOURNAL   J Otolaryngol 27 (5), 281-287 (1998)
   PUBMED   9800627
REFERENCE   8  (bases 1 to 807)
  AUTHORS   McManus,C., Berman,J.W., Brett,F.M., Staunton,H., Farrell,M. and
            Brosnan,C.F.
  TITLE     MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an
            immunohistochemical and in situ hybridization study
  JOURNAL   J Neuroimmunol 86 (1), 20-29 (1998)
   PUBMED   9655469
REFERENCE   9  (bases 1 to 807)
  AUTHORS   Kurihara,T. and Bravo,R.
  TITLE     Cloning and functional expression of mCCR2, a murine receptor for
            the C-C chemokines JE and FIC
  JOURNAL   J Biol Chem 271 (20), 11603-11607 (1996)
   PUBMED   8662823
REFERENCE   10 (bases 1 to 807)
  AUTHORS   Ben-Baruch,A., Xu,L., Young,P.R., Bengali,K., Oppenheim,J.J. and
            Wang,J.M.
  TITLE     Monocyte chemotactic protein-3 (MCP3) interacts with multiple
            leukocyte receptors. C-C CKR1, a receptor for macrophage
            inflammatory protein-1 alpha/Rantes, is also a functional receptor
            for MCP3
  JOURNAL   J Biol Chem 270 (38), 22123-22128 (1995)
   PUBMED   7545673
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF154245.2.
            
            On Nov 29, 2004 this sequence version replaced XM_213419.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM106368.1, BE128373.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132291, SAMD00132292
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..807
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..807
                     /gene="Ccl7"
                     /note="C-C motif chemokine ligand 7"
                     /db_xref="GeneID:287561"
                     /db_xref="RGD:1359152"
     exon            1..164
                     /gene="Ccl7"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..382
                     /gene="Ccl7"
                     /note="chemotactic protein-3; C-C motif chemokine 7;
                     MCP-3; small-inducible cytokine A7; chemokine (C-C motif)
                     ligand 7; monocyte chemotactic protein 3; monocyte
                     chemoattractant protein 3"
                     /codon_start=1
                     /product="C-C motif chemokine 7 precursor"
                     /protein_id="NP_001007613.1"
                     /db_xref="GeneID:287561"
                     /db_xref="RGD:1359152"
                     /translation="MQISAALLCVLLTAAAFTVHVWAQPDGTNSSTCCYVKKQKIPKR
                     NLKSYRKITSSRCPWEAVIFKTKKGMEVCAEAHQKWVEEAIAYLDMKTSTPKP"
     exon            165..276
                     /gene="Ccl7"
                     /inference="alignment:Splign:2.1.0"
     exon            277..807
                     /gene="Ccl7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaggcaagg ccagcaccga gtctgccaac tttcactgaa gccagcttca actttcactg
       61 aagccagcct tctctctctc tctccaccat gcagatctct gccgcgcttc tgtgtgtgct
      121 gctcacagct gctgctttca ccgtgcacgt gtgggcccaa ccagatggga ccaattcatc
      181 cacttgctgc tatgtcaaga aacaaaagat tcccaagagg aatctcaaga gttacagaaa
      241 gatcaccagt agtcggtgtc cctgggaagc tgttatcttc aagaccaaaa agggcatgga
      301 agtctgtgct gaagcccatc agaagtgggt tgaggaggcc atagcatact tagacatgaa
      361 aacttcaact ccaaagccct gaagacagat gcctgaacag aaaccaaccc tgaagtcaag
      421 aagcaaaatt cctcaccctt gtcctttctg agaactgtgc tgaaatgggt ggactacggt
      481 cctaaggggt aggaacggtc tgtaggaatg tgaaatagtc gctcctaagg aatggtcttt
      541 aagttattaa tatttttatt taatttgcca tgtactttgg tgtgatttga atgtaaagcc
      601 ctggagacct catgtcactt taatgttgtg ttacctgcag aattcttccc ccgccccatt
      661 gactttgttc ctgtattatg tagggacatt gcaagaatca gtgcaaatat tttatttaaa
      721 aatgtttagg acaaaatcat aatgttatga tactgtggga tgtttaaatg tatgactact
      781 gaagtttcat ataaaatgta tttttgc
//
