LOCUS       NM_013025                755 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Rattus norvegicus C-C motif chemokine ligand 3 (Ccl3), mRNA.
ACCESSION   NM_013025
VERSION     NM_013025.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Yang,Y., Shen,C., Li,J., Yuan,J., Wei,J., Huang,F., Wang,F., Li,G.,
            Li,Y., Xing,L., Peng,L., Yang,M., Cao,M., Zheng,H., Wu,W., Zou,R.,
            Li,D., Xu,Z., Wang,H., Zhang,M., Zhang,Z., Gao,G.F., Jiang,C.,
            Liu,L. and Liu,Y.
  TITLE     Plasma IP-10 and MCP-3 levels are highly associated with disease
            severity and predict the progression of COVID-19
  JOURNAL   J Allergy Clin Immunol 146 (1), 119-127 (2020)
   PUBMED   32360286
REFERENCE   2  (bases 1 to 755)
  AUTHORS   Liu,J., Zhang,S., Huang,Y. and Sun,L.
  TITLE     miR-21 protects neonatal rats from hypoxic-ischemic brain damage by
            targeting CCL3
  JOURNAL   Apoptosis 25 (3-4), 275-289 (2020)
   PUBMED   32306124
  REMARK    GeneRIF: miR-21 protects neonatal rats from hypoxic-ischemic brain
            damage by targeting CCL3.
REFERENCE   3  (bases 1 to 755)
  AUTHORS   Huang,C., Wang,Y., Li,X., Ren,L., Zhao,J., Hu,Y., Zhang,L., Fan,G.,
            Xu,J., Gu,X., Cheng,Z., Yu,T., Xia,J., Wei,Y., Wu,W., Xie,X.,
            Yin,W., Li,H., Liu,M., Xiao,Y., Gao,H., Guo,L., Xie,J., Wang,G.,
            Jiang,R., Gao,Z., Jin,Q., Wang,J. and Cao,B.
  TITLE     Clinical features of patients infected with 2019 novel coronavirus
            in Wuhan, China
  JOURNAL   Lancet 395 (10223), 497-506 (2020)
   PUBMED   31986264
  REMARK    Erratum:[Lancet. 2020 Feb 15;395(10223):496. doi:
            10.1016/S0140-6736(20)30252-X.. PMID: 32007144]
REFERENCE   4  (bases 1 to 755)
  AUTHORS   Iwata-Yoshikawa,N., Okamura,T., Shimizu,Y., Kotani,O., Sato,H.,
            Sekimukai,H., Fukushi,S., Suzuki,T., Sato,Y., Takeda,M.,
            Tashiro,M., Hasegawa,H. and Nagata,N.
  TITLE     Acute Respiratory Infection in Human Dipeptidyl Peptidase
            4-Transgenic Mice Infected with Middle East Respiratory Syndrome
            Coronavirus
  JOURNAL   J Virol 93 (6), e01818-18 (2019)
   PUBMED   30626685
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 755)
  AUTHORS   Zhang,H., Wu,J., Wu,J., Fan,Q., Zhou,J., Wu,J., Liu,S., Zang,J.,
            Ye,J., Xiao,M., Tian,T. and Gao,J.
  TITLE     Exosome-mediated targeted delivery of miR-210 for angiogenic
            therapy after cerebral ischemia in mice
  JOURNAL   J Nanobiotechnology 17 (1), 29 (2019)
   PUBMED   30782171
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 755)
  AUTHORS   Post,T.W., Bozic,C.R., Rothenberg,M.E., Luster,A.D., Gerard,N. and
            Gerard,C.
  TITLE     Molecular characterization of two murine eosinophil beta chemokine
            receptors
  JOURNAL   J Immunol 155 (11), 5299-5305 (1995)
   PUBMED   7594543
REFERENCE   7  (bases 1 to 755)
  AUTHORS   Ben-Baruch,A., Xu,L., Young,P.R., Bengali,K., Oppenheim,J.J. and
            Wang,J.M.
  TITLE     Monocyte chemotactic protein-3 (MCP3) interacts with multiple
            leukocyte receptors. C-C CKR1, a receptor for macrophage
            inflammatory protein-1 alpha/Rantes, is also a functional receptor
            for MCP3
  JOURNAL   J Biol Chem 270 (38), 22123-22128 (1995)
   PUBMED   7545673
REFERENCE   8  (bases 1 to 755)
  AUTHORS   Shi,M.M., Godleski,J.J. and Paulauskis,J.D.
  TITLE     Molecular cloning and posttranscriptional regulation of macrophage
            inflammatory protein-1 alpha in alveolar macrophages
  JOURNAL   Biochem Biophys Res Commun 211 (1), 289-295 (1995)
   PUBMED   7779098
REFERENCE   9  (bases 1 to 755)
  AUTHORS   Shanley,T.P., Schmal,H., Friedl,H.P., Jones,M.L. and Ward,P.A.
  TITLE     Role of macrophage inflammatory protein-1 alpha (MIP-1 alpha) in
            acute lung injury in rats
  JOURNAL   J Immunol 154 (9), 4793-4802 (1995)
   PUBMED   7722328
REFERENCE   10 (bases 1 to 755)
  AUTHORS   Santolini,B.M., Nai Fovino,P.L. and Rossoni,L.
  TITLE     [The behavior of intra-leukocyte peroxidase after irradiation with
            radar microwaves in intra-articular exudates]
  JOURNAL   Minerva Ortop 22 (12), 459-462 (1971)
   PUBMED   5135051
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U22414.1.
            
            On Dec 20, 2003 this sequence version replaced NM_013025.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U22414.1, DV728694.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN13663625 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..755
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="CD"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..755
                     /gene="Ccl3"
                     /gene_synonym="MIP-1a; Scya3"
                     /note="C-C motif chemokine ligand 3"
                     /db_xref="GeneID:25542"
                     /db_xref="RGD:3647"
     exon            1..145
                     /gene="Ccl3"
                     /gene_synonym="MIP-1a; Scya3"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..348
                     /gene="Ccl3"
                     /gene_synonym="MIP-1a; Scya3"
                     /note="C-C motif chemokine 3; MIP-1-alpha; small-inducible
                     cytokine A3; macrophage inflammatory protein 1-alpha;
                     Macrophage inflammatory protein 1 alpha (Small inducible
                     cytokine A3); chemokine (C-C motif) ligand 3"
                     /codon_start=1
                     /product="C-C motif chemokine 3 precursor"
                     /protein_id="NP_037157.2"
                     /db_xref="GeneID:25542"
                     /db_xref="RGD:3647"
                     /translation="MKVSTAALAVLLCTMALWNEVFSAPYGADTPTACCFSYGRQIPR
                     KFIADYFETSSLCSQPGVIFLTKRNRQICADPKETWVQEYITELELNA"
     exon            146..257
                     /gene="Ccl3"
                     /gene_synonym="MIP-1a; Scya3"
                     /inference="alignment:Splign:2.1.0"
     exon            258..754
                     /gene="Ccl3"
                     /gene_synonym="MIP-1a; Scya3"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      755
                     /gene="Ccl3"
                     /gene_synonym="MIP-1a; Scya3"
ORIGIN      
        1 agaggcagcg agtaccagtc ccttctctgc tctgctgaca agcgcaccct ctgttacctg
       61 ctcagcacca tgaaggtctc caccgctgcc cttgctgttc ttctctgcac catggcgctc
      121 tggaacgaag tcttctcagc gccatatgga gctgacaccc cgactgcctg ctgcttctcc
      181 tatggacggc aaattccacg aaaattcatt gctgactatt ttgagaccag cagcctttgc
      241 tcccagccgg gtgtcatttt cctgaccaag agaaaccggc agatctgcgc tgaccccaaa
      301 gagacctggg tccaagaata catcactgag ctggaactaa atgcctgaga ttagaggcag
      361 caaggaaccc ccaaacctcc gtgggccccg tgtagagcag gggcttgagc cccagaacat
      421 tcctgccacc tgcaaatctc cccctcctat aagctgtttg ctgccaagta gccacatcca
      481 gggactcttc acttgaattt ttatttaatt taatcctatt gatttaatac tatttaattt
      541 tttaatttat tttattgtca catttgtgtt tgtagctatt tattctgaaa gacctcaggg
      601 cacattcctc agccctcccc ccccctccca gttgctcaca ctgtgtttgg tgacaattat
      661 tctaggtaga cgtgatgaca aagtcatgaa ctgacaaatg tacaatggat gctttgtcta
      721 taccagagaa ataataaata tgctctttaa caaga
//
