LOCUS       NM_001108660             834 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus C-C motif chemokine ligand 27 (Ccl27), mRNA.
ACCESSION   NM_001108660 XM_001061271 XM_342823
VERSION     NM_001108660.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 834)
  AUTHORS   Yang,Y., Shen,C., Li,J., Yuan,J., Wei,J., Huang,F., Wang,F., Li,G.,
            Li,Y., Xing,L., Peng,L., Yang,M., Cao,M., Zheng,H., Wu,W., Zou,R.,
            Li,D., Xu,Z., Wang,H., Zhang,M., Zhang,Z., Gao,G.F., Jiang,C.,
            Liu,L. and Liu,Y.
  TITLE     Plasma IP-10 and MCP-3 levels are highly associated with disease
            severity and predict the progression of COVID-19
  JOURNAL   J Allergy Clin Immunol 146 (1), 119-127 (2020)
   PUBMED   32360286
REFERENCE   2  (bases 1 to 834)
  AUTHORS   Maerki,C., Meuter,S., Liebi,M., Muhlemann,K., Frederick,M.J.,
            Yawalkar,N., Moser,B. and Wolf,M.
  TITLE     Potent and broad-spectrum antimicrobial activity of CXCL14 suggests
            an immediate role in skin infections
  JOURNAL   J Immunol 182 (1), 507-514 (2009)
   PUBMED   19109182
REFERENCE   3  (bases 1 to 834)
  AUTHORS   Baumer,W., Seegers,U., Braun,M., Tschernig,T. and Kietzmann,M.
  TITLE     TARC and RANTES, but not CTACK, are induced in two models of
            allergic contact dermatitis. Effects of cilomilast and diflorasone
            diacetate on T-cell-attracting chemokines
  JOURNAL   Br J Dermatol 151 (4), 823-830 (2004)
   PUBMED   15491423
REFERENCE   4  (bases 1 to 834)
  AUTHORS   Kakinuma,T., Saeki,H., Tsunemi,Y., Fujita,H., Asano,N., Mitsui,H.,
            Tada,Y., Wakugawa,M., Watanabe,T., Torii,H., Komine,M., Asahina,A.,
            Nakamura,K. and Tamaki,K.
  TITLE     Increased serum cutaneous T cell-attracting chemokine (CCL27)
            levels in patients with atopic dermatitis and psoriasis vulgaris
  JOURNAL   J Allergy Clin Immunol 111 (3), 592-597 (2003)
   PUBMED   12642842
REFERENCE   5  (bases 1 to 834)
  AUTHORS   Hieshima,K., Ohtani,H., Shibano,M., Izawa,D., Nakayama,T.,
            Kawasaki,Y., Shiba,F., Shiota,M., Katou,F., Saito,T. and Yoshie,O.
  TITLE     CCL28 has dual roles in mucosal immunity as a chemokine with
            broad-spectrum antimicrobial activity
  JOURNAL   J Immunol 170 (3), 1452-1461 (2003)
   PUBMED   12538707
REFERENCE   6  (bases 1 to 834)
  AUTHORS   Gortz,A., Nibbs,R.J., McLean,P., Jarmin,D., Lambie,W., Baird,J.W.
            and Graham,G.J.
  TITLE     The chemokine ESkine/CCL27 displays novel modes of intracrine and
            paracrine function
  JOURNAL   J Immunol 169 (3), 1387-1394 (2002)
   PUBMED   12133963
REFERENCE   7  (bases 1 to 834)
  AUTHORS   Jarmin,D.I., Rits,M., Bota,D., Gerard,N.P., Graham,G.J.,
            Clark-Lewis,I. and Gerard,C.
  TITLE     Cutting edge: identification of the orphan receptor
            G-protein-coupled receptor 2 as CCR10, a specific receptor for the
            chemokine ESkine
  JOURNAL   J Immunol 164 (7), 3460-3464 (2000)
   PUBMED   10725696
REFERENCE   8  (bases 1 to 834)
  AUTHORS   Morales,J., Homey,B., Vicari,A.P., Hudak,S., Oldham,E., Hedrick,J.,
            Orozco,R., Copeland,N.G., Jenkins,N.A., McEvoy,L.M. and Zlotnik,A.
  TITLE     CTACK, a skin-associated chemokine that preferentially attracts
            skin-homing memory T cells
  JOURNAL   Proc Natl Acad Sci U S A 96 (25), 14470-14475 (1999)
   PUBMED   10588729
REFERENCE   9  (bases 1 to 834)
  AUTHORS   Baird,J.W., Nibbs,R.J., Komai-Koma,M., Connolly,J.A.,
            Ottersbach,K., Clark-Lewis,I., Liew,F.Y. and Graham,G.J.
  TITLE     ESkine, a novel beta-chemokine, is differentially spliced to
            produce secretable and nuclear targeted isoforms
  JOURNAL   J Biol Chem 274 (47), 33496-33503 (1999)
   PUBMED   10559234
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473962.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_342823.2, XM_001061271.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760389,
                              SAMN12840124 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..834
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     gene            1..834
                     /gene="Ccl27"
                     /note="C-C motif chemokine ligand 27"
                     /db_xref="GeneID:362505"
                     /db_xref="RGD:1304660"
     exon            1..358
                     /gene="Ccl27"
                     /inference="alignment:Splign:2.1.0"
     CDS             312..806
                     /gene="Ccl27"
                     /note="chemokine (C-C motif) ligand 27"
                     /codon_start=1
                     /product="C-C motif chemokine 27"
                     /protein_id="NP_001102130.1"
                     /db_xref="GeneID:362505"
                     /db_xref="RGD:1304660"
                     /translation="MSRLRRYEVALEAEEEIYWGCFYFFPWLRMWRRERSPMPPTSQR
                     LSLEPPRLPLTGWHPWNKTKEKQEALPLPSSTSCCTQLYRQPLPTRLLRRIVRVELQE
                     ADGDCHLQAVVLHLTRRSVCVHPQNRSLARWLERHGKRLQGTLPSLNPVLQKKMCPSP
                     QKQK"
     exon            359..418
                     /gene="Ccl27"
                     /inference="alignment:Splign:2.1.0"
     exon            419..516
                     /gene="Ccl27"
                     /inference="alignment:Splign:2.1.0"
     exon            517..649
                     /gene="Ccl27"
                     /inference="alignment:Splign:2.1.0"
     exon            650..834
                     /gene="Ccl27"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgactccag ccccttaaaa atctccattc agggcctaaa cgtcccagct atactgccgc
       61 tagacccctc tccttggtga ctccacgttc cggtccctag atagccatcc tcctaacgct
      121 ttaacttgta gtgatttcca tatcatccat cccatcctgt cccgatgtga ccattggctt
      181 ccgggagggc cacctgcctc agtgtacctg agtattcaga cttgtcctgg gaatgatgga
      241 aaagggaact tgcaactggg aataagtgtt cctatcatgc tgctccccag gaaccgttcg
      301 gagctcgaga catgtcgcga ttgaggagat acgaggtggc gctggaagcg gaggaggaga
      361 tctactgggg ctgcttctac ttttttcctt ggctgcgaat gtggcgcagg gagcggagtc
      421 cgatgcctcc aacaagccag agactaagtc tggaaccccc caggctcccg ctgacaggct
      481 ggcatccgtg gaacaagact aaggagaagc aagaagcctt gccactgccc tccagcacta
      541 gctgctgtac tcagctctat aggcaaccac tcccaaccag actactgagg aggatcgtcc
      601 gtgtggagct gcaggaggct gacggggact gccacctcca agctgttgtg cttcacctga
      661 ctcggcgcag tgtctgtgtt catccccaga accgtagcct ggctcggtgg ttagaacgcc
      721 atgggaaaag gctccagggg accctaccca gtttaaatcc ggtactacaa aagaaaatgt
      781 gcccgagccc ccaaaagcaa aagtaataaa gcaacattag acgataatct ccaa
//
