LOCUS       NM_057151                606 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus C-C motif chemokine ligand 17 (Ccl17), mRNA.
ACCESSION   NM_057151
VERSION     NM_057151.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 606)
  AUTHORS   Ge,Y., Waldemer,R.J., Nalluri,R., Nuzzi,P.D. and Chen,J.
  TITLE     RNAi screen reveals potentially novel roles of cytokines in
            myoblast differentiation
  JOURNAL   PLoS One 8 (7), e68068 (2013)
   PUBMED   23844157
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 606)
  AUTHORS   Vijayanand,P., Durkin,K., Hartmann,G., Morjaria,J., Seumois,G.,
            Staples,K.J., Hall,D., Bessant,C., Bartholomew,M., Howarth,P.H.,
            Friedmann,P.S. and Djukanovic,R.
  TITLE     Chemokine receptor 4 plays a key role in T cell recruitment into
            the airways of asthmatic patients
  JOURNAL   J Immunol 184 (8), 4568-4574 (2010)
   PUBMED   20237293
REFERENCE   3  (bases 1 to 606)
  AUTHORS   Aki,K., Shimizu,A., Masuda,Y., Kuwahara,N., Arai,T., Ishikawa,A.,
            Fujita,E., Mii,A., Natori,Y., Fukunaga,Y. and Fukuda,Y.
  TITLE     ANG II receptor blockade enhances anti-inflammatory macrophages in
            anti-glomerular basement membrane glomerulonephritis
  JOURNAL   Am J Physiol Renal Physiol 298 (4), F870-F882 (2010)
   PUBMED   20071465
REFERENCE   4  (bases 1 to 606)
  AUTHORS   Chiba,Y., Sato,S. and Misawa,M.
  TITLE     GGTI-2133, an inhibitor of geranylgeranyltransferase, inhibits
            infiltration of inflammatory cells into airways in mouse
            experimental asthma
  JOURNAL   Int J Immunopathol Pharmacol 22 (4), 929-935 (2009)
   PUBMED   20074456
REFERENCE   5  (bases 1 to 606)
  AUTHORS   Yogo,Y., Fujishima,S., Inoue,T., Saito,F., Shiomi,T., Yamaguchi,K.
            and Ishizaka,A.
  TITLE     Macrophage derived chemokine (CCL22), thymus and
            activation-regulated chemokine (CCL17), and CCR4 in idiopathic
            pulmonary fibrosis
  JOURNAL   Respir Res 10 (1), 80 (2009)
   PUBMED   19715610
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 606)
  AUTHORS   Jakubzick,C., Wen,H., Matsukawa,A., Keller,M., Kunkel,S.L. and
            Hogaboam,C.M.
  TITLE     Role of CCR4 ligands, CCL17 and CCL22, during Schistosoma mansoni
            egg-induced pulmonary granuloma formation in mice
  JOURNAL   Am J Pathol 165 (4), 1211-1221 (2004)
   PUBMED   15466387
REFERENCE   7  (bases 1 to 606)
  AUTHORS   Inoue,T., Fujishima,S., Ikeda,E., Yoshie,O., Tsukamoto,N., Aiso,S.,
            Aikawa,N., Kubo,A., Matsushima,K. and Yamaguchi,K.
  TITLE     CCL22 and CCL17 in rat radiation pneumonitis and in human
            idiopathic pulmonary fibrosis
  JOURNAL   Eur Respir J 24 (1), 49-56 (2004)
   PUBMED   15293604
REFERENCE   8  (bases 1 to 606)
  AUTHORS   Yang,D., Chen,Q., Hoover,D.M., Staley,P., Tucker,K.D., Lubkowski,J.
            and Oppenheim,J.J.
  TITLE     Many chemokines including CCL20/MIP-3alpha display antimicrobial
            activity
  JOURNAL   J Leukoc Biol 74 (3), 448-455 (2003)
   PUBMED   12949249
REFERENCE   9  (bases 1 to 606)
  AUTHORS   Miyazaki,E., Nureki,S., Fukami,T., Shigenaga,T., Ando,M., Ito,K.,
            Ando,H., Sugisaki,K., Kumamoto,T. and Tsuda,T.
  TITLE     Elevated levels of thymus- and activation-regulated chemokine in
            bronchoalveolar lavage fluid from patients with eosinophilic
            pneumonia
  JOURNAL   Am J Respir Crit Care Med 165 (8), 1125-1131 (2002)
   PUBMED   11956056
REFERENCE   10 (bases 1 to 606)
  AUTHORS   Kawasaki,S., Takizawa,H., Yoneyama,H., Nakayama,T., Fujisawa,R.,
            Izumizaki,M., Imai,T., Yoshie,O., Homma,I., Yamamoto,K. and
            Matsushima,K.
  TITLE     Intervention of thymus and activation-regulated chemokine
            attenuates the development of allergic airway inflammation and
            hyperresponsiveness in mice
  JOURNAL   J Immunol 166 (3), 2055-2062 (2001)
   PUBMED   11160256
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On Sep 13, 2022 this sequence version replaced NM_057151.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF312687.1, SRR23984936.1100008.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676810 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-205               JAXUCZ010000019.1  10209691-10209895   c
            206-323             JAXUCZ010000019.1  10208986-10209103   c
            324-606             JAXUCZ010000019.1  10208120-10208402   c
FEATURES             Location/Qualifiers
     source          1..606
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p13"
     gene            1..606
                     /gene="Ccl17"
                     /gene_synonym="Scya17; Tarc"
                     /note="C-C motif chemokine ligand 17"
                     /db_xref="GeneID:117518"
                     /db_xref="RGD:619924"
     exon            1..205
                     /gene="Ccl17"
                     /gene_synonym="Scya17; Tarc"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..417
                     /gene="Ccl17"
                     /gene_synonym="Scya17; Tarc"
                     /note="small inducible cytokine subfamily A (Cys-Cys),
                     member 17; C-C motif chemokine 17; chemokine (C-C motif)
                     ligand 17; CC chemokine TARC; small-inducible cytokine
                     A17; thymus and activation-regulated chemokine"
                     /codon_start=1
                     /product="C-C motif chemokine 17 precursor"
                     /protein_id="NP_476492.2"
                     /db_xref="GeneID:117518"
                     /db_xref="RGD:619924"
                     /translation="MKTFAWTSGTMMSLQMLLLAALLLGTSLQHASAARATNVGRECC
                     LDYFKGAIPIRKLVTWFRTSVECPRDAIVFETVQGRLICTDPKDKHVKKAIRHLKNQR
                     L"
     exon            206..323
                     /gene="Ccl17"
                     /gene_synonym="Scya17; Tarc"
                     /inference="alignment:Splign:2.1.0"
     exon            324..606
                     /gene="Ccl17"
                     /gene_synonym="Scya17; Tarc"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctagtctag aagaattata ggaggagaca ggaggcgtgg gatgacctcc gaagaggtta
       61 aataggtcac catgacgctg ggcaccaaga caagcagaag gacccatgaa gaccttcgcc
      121 tggacttctg gtaccatgat gtcacttcag atgctgctcc tggctgccct gcttctgggg
      181 acttctctgc agcatgccag cgctgctcga gccaccaatg taggccgaga gtgctgcctg
      241 gactacttca agggggccat tcccatcagg aagctggtga cgtggttcag gacctcagtg
      301 gagtgtccca gggatgccat cgtgtttgag actgtccagg gaaggcttat ctgcacagac
      361 cccaaagaca agcatgtgaa gaaggccatc agacacctga aaaaccaaag gctgtgatct
      421 tcccagcgag tcatttggag actccagagc tgctgtccat ggcctcaacc tcgagctgcc
      481 tgtgtccagt ggaggcctcg agagcccaag agctgccaca gagcaggagt ccctgtcccc
      541 tttgtataga ctcttgtgtg ctgcagacgc acacacaaaa gcacggatta aagtcttcct
      601 ccttca
//
