LOCUS       NM_001105822             540 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus C-C motif chemokine ligand 12 (Ccl12), mRNA.
ACCESSION   NM_001105822 XM_001081016 XM_213425
VERSION     NM_001105822.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 540)
  AUTHORS   Fang JZ, Li C, Liu XY, Hu TT, Fan ZS and Han ZG.
  TITLE     Hepatocyte-Specific Arid1a Deficiency Initiates Mouse
            Steatohepatitis and Hepatocellular Carcinoma
  JOURNAL   PLoS One 10 (11), e0143042 (2015)
   PUBMED   26569409
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 540)
  AUTHORS   Zubiria MG, Vidal-Bravo J, Spinedi E and Giovambattista A.
  TITLE     Relationship between impaired adipogenesis of retroperitoneal
            adipose tissue and hypertrophic obesity: role of endogenous
            glucocorticoid excess
  JOURNAL   J Cell Mol Med 18 (8), 1549-1561 (2014)
   PUBMED   24913911
REFERENCE   3  (bases 1 to 540)
  AUTHORS   Sennlaub F, Auvynet C, Calippe B, Lavalette S, Poupel L, Hu SJ,
            Dominguez E, Camelo S, Levy O, Guyon E, Saederup N, Charo IF,
            Rooijen NV, Nandrot E, Bourges JL, Behar-Cohen F, Sahel JA,
            Guillonneau X, Raoul W and Combadiere C.
  TITLE     CCR2(+) monocytes infiltrate atrophic lesions in age-related
            macular disease and mediate photoreceptor degeneration in
            experimental subretinal inflammation in Cx3cr1 deficient mice
  JOURNAL   EMBO Mol Med 5 (11), 1775-1793 (2013)
   PUBMED   24142887
REFERENCE   4  (bases 1 to 540)
  AUTHORS   Dhingra S, Li P, Huang XP, Guo J, Wu J, Mihic A, Li SH, Zang WF,
            Shen D, Weisel RD, Singal PK and Li RK.
  TITLE     Preserving prostaglandin E2 level prevents rejection of implanted
            allogeneic mesenchymal stem cells and restores postinfarction
            ventricular function
  JOURNAL   Circulation 128 (11 Suppl 1), S69-S78 (2013)
   PUBMED   24030423
REFERENCE   5  (bases 1 to 540)
  AUTHORS   Dhaouadi T, Sfar I, Aounallah-Skhiri H, Jendoubi-Ayed S, Bouacha H,
            Ben Abdallah T and Gorgi Y.
  TITLE     MCP-1, CCR2 and CCR5 polymorphisms in Tunisian patients with atopic
            asthma
  JOURNAL   Iran J Allergy Asthma Immunol 12 (1), 29-36 (2013)
   PUBMED   23454776
REFERENCE   6  (bases 1 to 540)
  AUTHORS   Silva TA, Garlet GP, Lara VS, Martins W Jr, Silva JS and Cunha FQ.
  TITLE     Differential expression of chemokines and chemokine receptors in
            inflammatory periapical diseases
  JOURNAL   Oral Microbiol Immunol 20 (5), 310-316 (2005)
   PUBMED   16101967
REFERENCE   7  (bases 1 to 540)
  AUTHORS   Yang D, Chen Q, Hoover DM, Staley P, Tucker KD, Lubkowski J and
            Oppenheim JJ.
  TITLE     Many chemokines including CCL20/MIP-3alpha display antimicrobial
            activity
  JOURNAL   J Leukoc Biol 74 (3), 448-455 (2003)
   PUBMED   12949249
REFERENCE   8  (bases 1 to 540)
  AUTHORS   Sabroe I, Hartnell A, Jopling LA, Bel S, Ponath PD, Pease JE,
            Collins PD and Williams TJ.
  TITLE     Differential regulation of eosinophil chemokine signaling via CCR3
            and non-CCR3 pathways
  JOURNAL   J Immunol 162 (5), 2946-2955 (1999)
   PUBMED   10072545
REFERENCE   9  (bases 1 to 540)
  AUTHORS   McTigue DM, Tani M, Krivacic K, Chernosky A, Kelner GS, Maciejewski
            D, Maki R, Ransohoff RM and Stokes BT.
  TITLE     Selective chemokine mRNA accumulation in the rat spinal cord after
            contusion injury
  JOURNAL   J Neurosci Res 53 (3), 368-376 (1998)
   PUBMED   9698165
REFERENCE   10 (bases 1 to 540)
  AUTHORS   Sarafi MN, Garcia-Zepeda EA, MacLean JA, Charo IF and Luster AD.
  TITLE     Murine monocyte chemoattractant protein (MCP)-5: a novel CC
            chemokine that is a structural and functional homologue of human
            MCP-1
  JOURNAL   J Exp Med 185 (1), 99-109 (1997)
   PUBMED   8996246
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_001081016.1, XM_213425.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760393,
                              SAMEA5760400 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..540
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..540
                     /gene="Ccl12"
                     /gene_synonym="MCP-5"
                     /note="C-C motif chemokine ligand 12"
                     /db_xref="GeneID:287562"
                     /db_xref="RGD:1309255"
     exon            1..124
                     /gene="Ccl12"
                     /gene_synonym="MCP-5"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..348
                     /gene="Ccl12"
                     /gene_synonym="MCP-5"
                     /note="monocyte chemotactic protein 5; chemokine (C-C
                     motif) ligand 12"
                     /codon_start=1
                     /product="C-C motif chemokine ligand 12 precursor"
                     /protein_id="NP_001099292.1"
                     /db_xref="GeneID:287562"
                     /db_xref="RGD:1309255"
                     /translation="MKISTLLCLLLIAAAISPQVLAGPDSVFTPVTCCYNVAKQKIHI
                     RRLKSYRKITSSQCPREAVIFRTVLDKELCADPKEKWVKDSMNHLDQKSRTQHP"
     exon            125..242
                     /gene="Ccl12"
                     /gene_synonym="MCP-5"
                     /inference="alignment:Splign:2.1.0"
     exon            243..540
                     /gene="Ccl12"
                     /gene_synonym="MCP-5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acactggctc ctgagtcctc cagctctcat tccaaagcct ttggcctcaa catgaagatc
       61 tccacccttc tttgccttct gctcatagct gccgccatca gcccacaggt gttggctgga
      121 ccagattcag tgttcacccc agtcacctgc tgttataatg tcgctaagca gaagatccac
      181 attcggaggc taaagagcta caggaaaatc acaagcagcc agtgtccccg ggaagctgtg
      241 atcttcagaa ctgtactgga taaggagctc tgtgctgacc ccaaggagaa gtgggttaag
      301 gactccatga accacttgga tcagaagtct cgaactcagc atccttgaac cttcacgtct
      361 aggctgaaag ttccagaaaa attacattta tttcctctga ccttccccat ggacagtgcg
      421 atagttattt attatgatat ctaaagagag atgcttttaa taatttaaaa cacaaactta
      481 ctgaagtaat atttaatgat atctaagtta tatttgggcc aattaaactg actttaattt
//
