LOCUS       NM_001191092             452 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus C-C motif chemokine ligand 1 (Ccl1), mRNA.
ACCESSION   NM_001191092 XM_001067590
VERSION     NM_001191092.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Zhong,L., Xiao,W., Wang,F., Liu,J. and Zhi,L.J.
  TITLE     miR-21-5p inhibits neuropathic pain development via directly
            targeting C-C motif ligand 1 and tissue inhibitor of
            metalloproteinase-3
  JOURNAL   J Cell Biochem 120 (10), 16614-16623 (2019)
   PUBMED   31161659
  REMARK    GeneRIF: miR-21-5p inhibits neuropathic pain development via
            directly targeting C-C motif ligand 1 and tissue inhibitor of
            metalloproteinase-3.
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Haque,N.S., Tuteja,A. and Haque,N.
  TITLE     CC chemokine CCL1 receptor CCR8 mediates conversion of mesenchymal
            stem cells to embryoid bodies expressing FOXP3+CCR8+ regulatory T
            cells
  JOURNAL   PLoS One 14 (7), e0218944 (2019)
   PUBMED   31314754
  REMARK    GeneRIF: We show a novel method for formation of Embryoid bodies
            (EBs) from mesenchymal stem cells under stress and demonstrate that
            the induction of FoxP3+ CCR8+ EBs is dependent upon CCL1 gradients
            which mediate cell proliferation, migration and invasion of mTregs.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 452)
  AUTHORS   Chang,R., Yi,S., Tan,X., Huang,Y., Wang,Q., Su,G., Zhou,C., Cao,Q.,
            Yuan,G., Kijlstra,A. and Yang,P.
  TITLE     MicroRNA-20a-5p suppresses IL-17 production by targeting OSM and
            CCL1 in patients with Vogt-Koyanagi-Harada disease
  JOURNAL   Br J Ophthalmol 102 (2), 282-290 (2018)
   PUBMED   28972028
REFERENCE   4  (bases 1 to 452)
  AUTHORS   Fang,J.Z., Li,C., Liu,X.Y., Hu,T.T., Fan,Z.S. and Han,Z.G.
  TITLE     Hepatocyte-Specific Arid1a Deficiency Initiates Mouse
            Steatohepatitis and Hepatocellular Carcinoma
  JOURNAL   PLoS One 10 (11), e0143042 (2015)
   PUBMED   26569409
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 452)
  AUTHORS   Kim,Y.M., Munoz,A., Hwang,P.H. and Nadeau,K.C.
  TITLE     Migration of regulatory T cells toward airway epithelial cells is
            impaired in chronic rhinosinusitis with nasal polyposis
  JOURNAL   Clin Immunol 137 (1), 111-121 (2010)
   PUBMED   20598643
REFERENCE   6  (bases 1 to 452)
  AUTHORS   Ou,Z.L., Nakayama,K., Natori,Y., Doi,N., Saito,T. and Natori,Y.
  TITLE     Effective methylprednisolone dose in experimental crescentic
            glomerulonephritis
  JOURNAL   Am J Kidney Dis 37 (2), 411-417 (2001)
   PUBMED   11157384
REFERENCE   7  (bases 1 to 452)
  AUTHORS   Haeberle,H.A., Kuziel,W.A., Dieterich,H.J., Casola,A., Gatalica,Z.
            and Garofalo,R.P.
  TITLE     Inducible expression of inflammatory chemokines in respiratory
            syncytial virus-infected mice: role of MIP-1alpha in lung pathology
  JOURNAL   J Virol 75 (2), 878-890 (2001)
   PUBMED   11134301
REFERENCE   8  (bases 1 to 452)
  AUTHORS   Ou,Z.L., Natori,Y. and Natori,Y.
  TITLE     Transient and sequential expression of chemokine mRNA in glomeruli
            in puromycin aminonucleoside nephrosis
  JOURNAL   Nephron 85 (3), 254-257 (2000)
   PUBMED   10867541
REFERENCE   9  (bases 1 to 452)
  AUTHORS   Zingoni,A., Soto,H., Hedrick,J.A., Stoppacciaro,A., Storlazzi,C.T.,
            Sinigaglia,F., D'Ambrosio,D., O'Garra,A., Robinson,D., Rocchi,M.,
            Santoni,A., Zlotnik,A. and Napolitano,M.
  TITLE     The chemokine receptor CCR8 is preferentially expressed in Th2 but
            not Th1 cells
  JOURNAL   J Immunol 161 (2), 547-551 (1998)
   PUBMED   9670926
REFERENCE   10 (bases 1 to 452)
  AUTHORS   Miller,M.D. and Krangel,M.S.
  TITLE     The human cytokine I-309 is a monocyte chemoattractant
  JOURNAL   Proc Natl Acad Sci U S A 89 (7), 2950-2954 (1992)
   PUBMED   1557400
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000010.1.
            
            On Jul 17, 2010 this sequence version replaced XM_001067590.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760494,
                              SAMN06621351 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-76                JAXUCZ010000010.1  67628665-67628740   c
            77-191              JAXUCZ010000010.1  67627516-67627630   c
            192-452             JAXUCZ010000010.1  67625962-67626222   c
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..452
                     /gene="Ccl1"
                     /note="C-C motif chemokine ligand 1"
                     /db_xref="GeneID:688605"
                     /db_xref="RGD:1586495"
     CDS             1..279
                     /gene="Ccl1"
                     /note="C-C motif chemokine 1; chemokine (C-C motif) ligand
                     1"
                     /codon_start=1
                     /product="C-C motif chemokine 1 precursor"
                     /protein_id="NP_001178021.1"
                     /db_xref="GeneID:688605"
                     /db_xref="RGD:1586495"
                     /translation="MKLLNMVLVCLLVAAMWLQNVDSKSMHVVSSRCCLNTLENKIAL
                     KFIKCYKEIGPSCPYYPAVIFRLIKGRESCALTNTTWVQDYLKKVKPC"
     exon            1..76
                     /gene="Ccl1"
                     /inference="alignment:Splign:2.1.0"
     exon            77..191
                     /gene="Ccl1"
                     /inference="alignment:Splign:2.1.0"
     exon            192..452
                     /gene="Ccl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgaaactcc tcaacatggt actggtgtgc ctgctggtgg ctgccatgtg gctacagaat
       61 gtggacagca agagcatgca cgtggtctcc tctagatgct gcttgaacac cttggagaac
      121 aagattgccc tgaagtttat caaatgttac aaagagatcg gccccagctg tccttactac
      181 ccagctgtaa tattcaggct gataaaaggt agagaaagct gcgccttaac taacaccacg
      241 tgggttcaag attacctgaa gaaggtgaag ccctgctaat tggggtgaag ataagctacc
      301 ttcccatccc agcaccagag cctgcagttt cactcaggcc tcctcccctc aaccacagcc
      361 atctctctgc ctactgatgc aggctcacag atctcagtca tgtgataagc tatattatgg
      421 tattttatct gtttaaacta tggaatcttc aa
//
