LOCUS       NM_001135837            2570 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus coiled-coil domain containing 22 (Ccdc22), mRNA.
ACCESSION   NM_001135837 XM_228770
VERSION     NM_001135837.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2570)
  AUTHORS   McNally,K.E., Faulkner,R., Steinberg,F., Gallon,M., Ghai,R.,
            Pim,D., Langton,P., Pearson,N., Danson,C.M., Nagele,H.,
            Morris,L.L., Singla,A., Overlee,B.L., Heesom,K.J., Sessions,R.,
            Banks,L., Collins,B.M., Berger,I., Billadeau,D.D., Burstein,E. and
            Cullen,P.J.
  TITLE     Retriever is a multiprotein complex for retromer-independent
            endosomal cargo recycling
  JOURNAL   Nat Cell Biol 19 (10), 1214-1225 (2017)
   PUBMED   28892079
REFERENCE   2  (bases 1 to 2570)
  AUTHORS   Phillips-Krawczak,C.A., Singla,A., Starokadomskyy,P., Deng,Z.,
            Osborne,D.G., Li,H., Dick,C.J., Gomez,T.S., Koenecke,M.,
            Zhang,J.S., Dai,H., Sifuentes-Dominguez,L.F., Geng,L.N.,
            Kaufmann,S.H., Hein,M.Y., Wallis,M., McGaughran,J., Gecz,J.,
            Sluis,Bv., Billadeau,D.D. and Burstein,E.
  TITLE     COMMD1 is linked to the WASH complex and regulates endosomal
            trafficking of the copper transporter ATP7A
  JOURNAL   Mol Biol Cell 26 (1), 91-103 (2015)
   PUBMED   25355947
REFERENCE   3  (bases 1 to 2570)
  AUTHORS   Starokadomskyy,P., Gluck,N., Li,H., Chen,B., Wallis,M., Maine,G.N.,
            Mao,X., Zaidi,I.W., Hein,M.Y., McDonald,F.J., Lenzner,S., Zecha,A.,
            Ropers,H.H., Kuss,A.W., McGaughran,J., Gecz,J. and Burstein,E.
  TITLE     CCDC22 deficiency in humans blunts activation of proinflammatory
            NF-kappaB signaling
  JOURNAL   J Clin Invest 123 (5), 2244-2256 (2013)
   PUBMED   23563313
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Oct 15, 2008 this sequence version replaced XM_228770.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643284.21267.1,
                                           SRR26643285.22069.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-182               JAXUCZ010000021.1  17570184-17570365
            183-360             JAXUCZ010000021.1  17571328-17571505
            361-493             JAXUCZ010000021.1  17574785-17574917
            494-600             JAXUCZ010000021.1  17575838-17575944
            601-667             JAXUCZ010000021.1  17576072-17576138
            668-846             JAXUCZ010000021.1  17576236-17576414
            847-1041            JAXUCZ010000021.1  17577835-17578029
            1042-1104           JAXUCZ010000021.1  17578791-17578853
            1105-1224           JAXUCZ010000021.1  17579031-17579150
            1225-1344           JAXUCZ010000021.1  17579612-17579731
            1345-1461           JAXUCZ010000021.1  17579814-17579930
            1462-1563           JAXUCZ010000021.1  17580032-17580133
            1564-1671           JAXUCZ010000021.1  17580215-17580322
            1672-1767           JAXUCZ010000021.1  17580560-17580655
            1768-1827           JAXUCZ010000021.1  17580893-17580952
            1828-1902           JAXUCZ010000021.1  17581032-17581106
            1903-2570           JAXUCZ010000021.1  17581463-17582130
FEATURES             Location/Qualifiers
     source          1..2570
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq12"
     gene            1..2570
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /note="coiled-coil domain containing 22"
                     /db_xref="GeneID:317381"
                     /db_xref="RGD:1560910"
     exon            1..182
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     CDS             133..2016
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 22"
                     /protein_id="NP_001129309.1"
                     /db_xref="GeneID:317381"
                     /db_xref="RGD:1560910"
                     /translation="MEEADRILIHSLRQAGTAVPPEVQTLRAFTTELVVEAVVRCLRV
                     INPDVGSGLSHLLPPAMSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLL
                     FLAERLPTDASEDADQPAGDSAIFLRAIGSQIRDQLALPWVPPLLRTPKVQRLQGSAL
                     QQAFHSSRLVLPELNCRGEPREFQASPLLLPAPSQVPQLLGRAASLLEHHAIQLCQHV
                     NRDCPGDEDRVRWASRLPSQEDPRAPQQRLHKQLIEHLRQSWGPLGAPTQVRDLGEML
                     QAWGAKAMTGVPKGSRFTHSEKFTFHLEPQVQAAQVADIPAASQRPEQDTRAAQEEEL
                     ESLREQLASVNHNIEEVEANMKSLGMNLVQVETECRQSELSVAEQEQALRLKSRTVEL
                     LPDGAANLTKLQLVVESSAQRLIHLASQWEKHRVPLLAEYRHLRKLQDCRELESSRRL
                     VEIQELHQSVRAAAEEARRKEEVYKQLVSELETLPKDVSRLAYTQRILEIVGNIRKQK
                     EEITKILSDTKELQKEINSLSGKLDRTFAVTDELVFKDAKKDDAVRKAYKYLAALHEN
                     CSQLIQTIEDTGTIMREVRDLEEQIETEMGKKTLSNLEKICEDYRALRQENAGLLGRV
                     REV"
     exon            183..360
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            361..493
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            494..600
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            601..667
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            668..846
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            847..1041
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1104
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1224
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..1344
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1461
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            1462..1563
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            1564..1671
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1767
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            1768..1827
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            1828..1902
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
     exon            1903..2570
                     /gene="Ccdc22"
                     /gene_synonym="RGD1560910"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tacacttccc aatgttcctc gcgcggcacg tgacgctctg tcctcggcgc gctgagagca
       61 gttactacaa cgttgctcca ctttctctga cctggtccta gacccagccc cggagttaga
      121 attaactcca ccatggagga ggctgaccga atcctcatcc attccttgcg ccaggcgggc
      181 acggcagttc ctccagaagt gcagactctt cgagctttca ccacggagct ggttgtagag
      241 gctgtggtcc gatgccttcg agtgatcaat cctgatgtgg gctctggcct cagtcacttg
      301 ctaccaccag ccatgtctgc ccgcttccgc ctggccatga gtctggctca ggcctgcatg
      361 gacctgggct atcccttgga gcttggctat cagaacttcc tctatcccag tgagcctgac
      421 ctccgagacc tacttctctt cttggctgag cggctaccca ccgatgcttc tgaggatgca
      481 gaccagcctg caggtgactc ggctattttc cttcgggcca ttgggagcca aatccgggac
      541 cagctggccc tgccctgggt cccacctctc cttcgaactc ccaaggtgca gcgtctccag
      601 ggctcagccc tccagcaagc attccactcc agcaggttgg ttctgcctga attgaattgc
      661 cgaggagagc cacgggagtt ccaggccagt cccctgctgc taccagcccc ctcacaggtg
      721 ccccagcttc tggggagggc agcctcgctc cttgaacacc atgccatcca gctctgccag
      781 catgtgaaca gggattgccc aggagatgaa gaccgagtgc gctgggcatc ccgcctccca
      841 tcccaggagg atccccgggc tccacagcag agactgcaca agcagctgat tgaacatctg
      901 cgtcaaagct ggggcccact tggagccccg acacaagtcc gagacctagg agagatgcta
      961 caggcctggg gtgctaaggc tatgactggc gtgcccaaag gctcccgctt cacccattca
     1021 gagaagttta ccttccatct ggagccccag gtccaggcag ctcaggtggc agatatacca
     1081 gctgcctctc aaaggcctga acaggacaca cgggcagctc aagaggagga gttagagtcc
     1141 ctccgggagc agctggcgag tgtgaaccac aacattgaag aggttgaagc taacatgaag
     1201 agcctgggaa tgaaccttgt gcaggtggaa actgagtgtc gacaaagtga actcagcgtg
     1261 gctgagcagg agcaagccct gcgcctgaag agcaggacgg tggagctgct gcctgatggg
     1321 gctgccaacc tcaccaagct gcagcttgtg gtggagagta gtgctcagag gctcattcat
     1381 ctagcaagtc agtgggagaa gcaccgggtc ccacttcttg ctgagtatcg ccacctcagg
     1441 aaactccagg attgtaggga gctggaatca tctcgaagac tggtagaaat ccaggagctg
     1501 caccagagtg tgcgagcggc tgcagaagag gctcgcagga aggaggaggt ctataagcag
     1561 ttggtatcag agctggaaac cctgccaaaa gatgtatccc gcctggccta tacccagcgc
     1621 atcctggaga ttgtgggcaa catccggaag cagaaggaag agatcactaa aatcttgtca
     1681 gacacaaagg aacttcagaa ggaaatcaac tctctctctg ggaagctgga ccggacattt
     1741 gcagtgactg atgagcttgt gttcaaggat gctaagaagg atgatgctgt tcggaaagcc
     1801 tacaaatatc tagctgctct gcatgagaat tgcagccagc tcatccagac cattgaggac
     1861 acgggcacta tcatgaggga agttcgagat cttgaggagc agattgagac agagatgggc
     1921 aagaagactt tgagcaacct ggagaagatc tgtgaggact accgagccct tcgccaggag
     1981 aatgctggcc tcttgggccg ggtccgagag gtctagagcc ctgatggatg tctcctaagc
     2041 acaggcagga atttgggggt actggagacc gtgctgaagc acttggctct agcactctct
     2101 tcaatttggt atccactttc tcctgttggg accttaaacc cagctgtctg cttatctgtt
     2161 cccatatctg atcagggtga ttgtccagct tgaccacagt ttattggatg ggcactgggg
     2221 accaggggcc ttggattcca aataaaagag aagttcttct gtgggccacg cttaggcatg
     2281 gattggggct tgggggtagg ggactggggt tagtggcaag tgatacatgg ggtacatttt
     2341 ggaaagtcgg tgtgtattca tggaactcag gagatacggt ggaggggctg catgtgtgta
     2401 catgtacacg tgtgcgttct gacaagctgt gtctgacttg atattttttg ggcattacta
     2461 gaggctacgt atgatcagtt atgcctgtgt ggttttctgg gatgctaatt ctgaaggttc
     2521 cagcgctgct cctgtacgag ggtctgcatc tacacccctg ctatgtgtca
//
