LOCUS       NM_001009659            1793 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Rattus norvegicus coiled-coil domain containing 174 (Ccdc174),
            mRNA.
ACCESSION   NM_001009659 XM_216221
VERSION     NM_001009659.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1793)
  AUTHORS   Volodarsky,M., Lichtig,H., Leibson,T., Sadaka,Y., Kadir,R.,
            Perez,Y., Liani-Leibson,K., Gradstein,L., Shaco-Levy,R., Shorer,Z.,
            Frank,D. and Birk,O.S.
  TITLE     CDC174, a novel component of the exon junction complex whose
            mutation underlies a syndrome of hypotonia and psychomotor
            developmental delay
  JOURNAL   Hum Mol Genet 24 (22), 6485-6491 (2015)
   PUBMED   26358778
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC087050.1, CA334689.1 and BE106912.1.
            
            On Oct 1, 2011 this sequence version replaced NM_001009659.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087050.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1024              BC087050.1         1-1024
            1025-1140           CA334689.1         551-666
            1141-1501           BC087050.1         1141-1501
            1502-1793           BE106912.1         1-292               c
FEATURES             Location/Qualifiers
     source          1..1793
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..1793
                     /gene="Ccdc174"
                     /gene_synonym="RGD1305225"
                     /note="coiled-coil domain containing 174"
                     /db_xref="GeneID:297458"
                     /db_xref="RGD:1305225"
     exon            1..114
                     /gene="Ccdc174"
                     /gene_synonym="RGD1305225"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..1497
                     /gene="Ccdc174"
                     /gene_synonym="RGD1305225"
                     /note="uncharacterized protein C3orf19 homolog"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 174"
                     /protein_id="NP_001009659.2"
                     /db_xref="GeneID:297458"
                     /db_xref="RGD:1305225"
                     /translation="MDRKKKPLDVTASSLVDLKAELFRKQEEFKQEKLLKDSGVFGKP
                     KTSNKKPSIWSKQNAGVSSRAEKDAEQKLEEQKTLDKSREKLEEKAKLYEKMTKGDFL
                     DEEVEDMYLVDFTQKIIDKRKEMEVLGATRDSRIKEERDAAVAAANDDDDEEEFSEKD
                     IPPPQDPSEEWVDYVDSLGRSRRCMRKDLPSLLEMDKNLQGRLFVSPANEKTLLSEDM
                     RKELQRQQWEEEEREALKKPMGPIHYEDIRENEARQLGVGYFAFARDKELRNKQMKTL
                     EMLREQTTDQRIKRENIKEKRKAILEARLAKLRQKKMKKSKEDGTEEESRADGVVTEP
                     SEPKSVPAPPPVAQSSKVEVIIQERKDSKPGVPHIREWDRGKDFSFGFWSKKQSELRA
                     ERDPEFAPPSNYFVGQKRTGSLSSQPWSRPGAAPSDLGHSSGQSQEPSSSHTSTPASE
                     SSPQAPTVTFQTLDDMISYYKQVT"
     exon            115..219
                     /gene="Ccdc174"
                     /gene_synonym="RGD1305225"
                     /inference="alignment:Splign:2.1.0"
     exon            220..320
                     /gene="Ccdc174"
                     /gene_synonym="RGD1305225"
                     /inference="alignment:Splign:2.1.0"
     exon            321..379
                     /gene="Ccdc174"
                     /gene_synonym="RGD1305225"
                     /inference="alignment:Splign:2.1.0"
     exon            380..584
                     /gene="Ccdc174"
                     /gene_synonym="RGD1305225"
                     /inference="alignment:Splign:2.1.0"
     exon            585..680
                     /gene="Ccdc174"
                     /gene_synonym="RGD1305225"
                     /inference="alignment:Splign:2.1.0"
     exon            681..823
                     /gene="Ccdc174"
                     /gene_synonym="RGD1305225"
                     /inference="alignment:Splign:2.1.0"
     exon            824..918
                     /gene="Ccdc174"
                     /gene_synonym="RGD1305225"
                     /inference="alignment:Splign:2.1.0"
     exon            919..1051
                     /gene="Ccdc174"
                     /gene_synonym="RGD1305225"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1201
                     /gene="Ccdc174"
                     /gene_synonym="RGD1305225"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..1777
                     /gene="Ccdc174"
                     /gene_synonym="RGD1305225"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggcggact cgtagggtct gactgaggcc acagggagac cgggtcccgg gacccgacac
       61 cttggcggga cgatggatcg aaagaaaaag cctttggacg ttacagcctc ctcgttggta
      121 gatcttaagg ctgagctttt ccgaaaacaa gaagaattca aacaagaaaa acttctaaaa
      181 gattctggag tttttggaaa accaaagaca tctaataaga agccaagtat ctggagcaaa
      241 caaaatgcag gtgtttccag tcgagcagag aaggacgctg aacagaagct tgaggagcag
      301 aagactttag acaaatcaag ggaaaaattg gaagaaaagg ccaaattata tgaaaagatg
      361 actaaaggag attttctaga tgaggaagtg gaggacatgt accttgtgga tttcacacag
      421 aaaatcatag acaagcgaaa agaaatggag gtgcttggtg ccactagaga ttcccgaatc
      481 aaagaagaga gagatgctgc tgttgctgct gctaatgatg atgatgatga agaagagttt
      541 tctgaaaaag acatacctcc ccctcaagac cccagtgagg aatgggtgga ttatgtggac
      601 tctttgggcc gatcccggcg ctgcatgaga aaggatttac caagtctatt ggagatggat
      661 aaaaatcttc aggggagact ttttgttagt cctgctaatg aaaagacttt gttatctgaa
      721 gacatgagga aagaacttca gcgccaacaa tgggaggaag aagaaaggga ggctttgaaa
      781 aaaccaatgg ggcccatcca ctatgaagac attcgggaaa atgaggcccg gcaacttggt
      841 gttgggtatt ttgcctttgc ccgagacaaa gagttgagaa acaagcaaat gaaaacttta
      901 gagatgcttc gtgagcagac aacagatcag agaataaaac gagaaaacat aaaggaaaag
      961 cgaaaagcta tcttagaagc aagacttgcc aagcttcgac aaaaaaagat gaaaaagtca
     1021 aaggaggatg ggactgaaga ggaaagcaga gcagatggag ttgttactga gccctcagaa
     1081 ccaaagtctg tacctgctcc acctcctgtg gcccagagca gcaaggtgga agtcatcatc
     1141 caggagagga aggacagcaa gcctggagtg ccacacatcc gagagtggga ccgagggaaa
     1201 gacttttcct ttggattctg gtcgaagaag cagtcagaac tccgggctga gcgagatcct
     1261 gagtttgccc caccttcaaa ttactttgtg ggtcaaaaga gaactggttc tttgagtagc
     1321 cagccatgga gcagaccagg agcagcacca agtgacttgg ggcattcctc tggccagagc
     1381 caggaaccca gctcttcaca cacatccact cctgcctctg aaagctcacc acaagcaccc
     1441 acagtcactt tccaaacact agatgatatg atatcttatt ataaacaagt cacatgacct
     1501 tgttaagcat gctggttgca tttgtgtctt agaagtcagg acaggactgg gttttacttc
     1561 tttcttctgt actttcccaa ggatgcacag gcttgaggcc atattagttg gcagggagaa
     1621 gtgagtgtat gatgagagct cattgactat ttggtggttc attattttat ctcttggtat
     1681 agagggacta tctcctccct ccatgctgac ccagttgtaa ctcacttggg tttccagctg
     1741 tgtgaagcat atataaatcc taatctgaga actctgaaaa aaaaaaaaaa aaa
//
