LOCUS       NM_001109049             956 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus dynein axonemal assembly factor 19 (Dnaaf19),
            mRNA.
ACCESSION   NM_001109049 XM_001081527 XM_573202
VERSION     NM_001109049.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 956)
  AUTHORS   Panizzi,J.R., Becker-Heck,A., Castleman,V.H., Al-Mutairi,D.A.,
            Liu,Y., Loges,N.T., Pathak,N., Austin-Tse,C., Sheridan,E.,
            Schmidts,M., Olbrich,H., Werner,C., Haffner,K., Hellman,N.,
            Chodhari,R., Gupta,A., Kramer-Zucker,A., Olale,F., Burdine,R.D.,
            Schier,A.F., O'Callaghan,C., Chung,E.M., Reinhardt,R.,
            Mitchison,H.M., King,S.M., Omran,H. and Drummond,I.A.
  TITLE     CCDC103 mutations cause primary ciliary dyskinesia by disrupting
            assembly of ciliary dynein arms
  JOURNAL   Nat Genet 44 (6), 714-719 (2012)
   PUBMED   22581229
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001081527.1, XM_573202.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: FQ212882.1 [ECO:0000331]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..956
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..956
                     /gene="Dnaaf19"
                     /gene_synonym="Ccdc103; RGD1562370"
                     /note="dynein axonemal assembly factor 19"
                     /db_xref="GeneID:498006"
                     /db_xref="RGD:1562370"
     exon            1..96
                     /gene="Dnaaf19"
                     /gene_synonym="Ccdc103; RGD1562370"
                     /inference="alignment:Splign:2.1.0"
     exon            97..176
                     /gene="Dnaaf19"
                     /gene_synonym="Ccdc103; RGD1562370"
                     /inference="alignment:Splign:2.1.0"
     exon            177..328
                     /gene="Dnaaf19"
                     /gene_synonym="Ccdc103; RGD1562370"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..899
                     /gene="Dnaaf19"
                     /gene_synonym="Ccdc103; RGD1562370"
                     /note="coiled-coil domain containing 103"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 103"
                     /protein_id="NP_001102519.1"
                     /db_xref="GeneID:498006"
                     /db_xref="RGD:1562370"
                     /translation="MEKTDVINFKALEKELQAALAADEKYKRENAAKLRAVEQRVPSY
                     EEFRGIVLASHLKPLEQKDKVGGRRFVSWNCHTTREKTSQDVVTEMPQEKSPVQPTTS
                     AEFYRDWRRHLRSGSERYQALLQLGGSKLGHLFQTDVGFGLLGELLVALAEHVKPSDR
                     RAVLGILHSLANTGRFTLNLSLLSHAERESCQLLFQKLQAMGTTRPMQEGLSMEEPSA
                     GLQGEEGLLQELLGLYGIH"
     exon            329..461
                     /gene="Dnaaf19"
                     /gene_synonym="Ccdc103; RGD1562370"
                     /inference="alignment:Splign:2.1.0"
     exon            462..956
                     /gene="Dnaaf19"
                     /gene_synonym="Ccdc103; RGD1562370"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 accgctgttg gctgggcgat cctctaaggt gttcgttcta acagatcgag gggctttttc
       61 aaaagaaagc aaaaggtcca agactggggc tactggtgag aaaccttgaa tacattttca
      121 tcacctaatt ccattttacc tgtaaaggag gaagctagat ttttgtaaca ctccaggcct
      181 tagccatgga gaagaccgat gtaatcaact tcaaggctct ggagaaagag ctgcaggctg
      241 ccctggctgc tgacgaaaag tacaaaaggg agaacgcagc caagttacgg gctgtggagc
      301 aaagggtgcc ttcctatgag gagttcagag ggattgttct tgcatcacac ctgaaacctc
      361 tggaacaaaa ggacaaagta ggaggaagga gatttgtgtc ctggaactgt catactactc
      421 gggaaaagac ttctcaagat gtggtcactg aaatgcccca ggagaaatca ccggtgcagc
      481 ccaccacctc tgcagaattt taccgcgatt ggcggcgaca cttacgaagt gggtcagagc
      541 gctaccaagc cctgctccag cttggggggt ccaagctggg ccacctcttc cagacagatg
      601 tgggctttgg acttctcggg gagttgctgg tggcattggc tgagcatgtg aagccgagtg
      661 atcggagggc agtgctaggg attctgcaca gcctggctaa cactgggcgg ttcaccttaa
      721 acctcagcct gctgagccac gcagagcgag agagctgcca gctcttgttt cagaagttgc
      781 aggccatggg caccaccaga cccatgcagg agggcctcag catggaggag ccatctgctg
      841 ggctacaggg agaagaaggg ctcctacagg agctgctcgg actgtatgga atccattgat
      901 aggactggct gccctcagca ttcctcagaa gacattttaa aaaggccttt tacgcg
//
