LOCUS       XM_017601124            5624 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus collagen and calcium binding EGF
            domains 1 (Ccbe1), transcript variant X1, mRNA.
ACCESSION   XM_017601124
VERSION     XM_017601124.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051353.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017601124.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017601124.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5624
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5624
                     /gene="Ccbe1"
                     /note="collagen and calcium binding EGF domains 1; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 9 ESTs, 4 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 59 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:361341"
                     /db_xref="RGD:1307670"
     CDS             69..1295
                     /gene="Ccbe1"
                     /codon_start=1
                     /product="collagen and calcium-binding EGF
                     domain-containing protein 1 isoform X1"
                     /protein_id="XP_017456613.1"
                     /db_xref="GeneID:361341"
                     /db_xref="RGD:1307670"
                     /translation="MVPPLPLSRGGAVKGQLGKSLGPLLLLLALGHTWTFREEPEDRD
                     REVCSENKITTTKYPCLKSSGELTTCFRKKCCKGYKFVLGQCIPEDYDICAQAPCEQQ
                     CTDNFGRVLCTCYPGYRYDRERHQKREKPYCLDIDECATGNTTLCAHTCVNTMGSYHC
                     ECREGYILEDDGRTCTRGDKYPNDTGHEEKSENEVKAGTCCATCKEFSQMKQTVLQLK
                     QKISLLPNNAAELGKYVNGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPG
                     PPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRHGLKGERGAPGPPGSPGPP
                     GSFDFLLLVLADIRNDIAELQEKVFGHRIHSSAEDFPLPQEFSSYPETLDFGSGDDYS
                     RRTEARDSEAPRNFYP"
ORIGIN      
        1 cggagcctcc ccgggcacag cgcagggaga gagctcgggt gccgagaaga agccggcgag
       61 cttccccgat ggtgccgccg cttcctctga gccggggagg agcagtcaag gggcagctgg
      121 gcaagagcct ggggccgctg ctgctactcc tggcgctggg acacacgtgg accttccgag
      181 aggaacccga ggaccgagac agagaagtgt gctcggaaaa caagatcacc acgaccaaat
      241 acccgtgtct gaagtcttca ggcgagctca ccacgtgctt caggaaaaaa tgctgcaaag
      301 gatataaatt tgtccttgga cagtgtattc cagaagatta tgacatttgt gcccaagctc
      361 cctgtgaaca gcaatgcacg gataacttcg gccgtgtgct gtgcacgtgc tatccaggat
      421 accgatatga ccgagagagg caccaaaagc gggagaagcc atactgcctg gatatcgatg
      481 agtgtgccac cggcaacacc actctgtgtg cacatacctg cgtcaacacc atgggcagct
      541 accactgtga gtgtcgggag ggctacatcc ttgaggacga tgggaggacc tgcacgaggg
      601 gagacaaata ccccaatgac actgggcatg aggagaagtc cgagaatgag gtgaaagctg
      661 ggacctgctg tgccacatgc aaggagttct cccagatgaa gcagacggtg ctgcagctga
      721 agcagaagat ttctctgctc cccaacaatg ccgccgaact gggcaagtat gtcaatggtg
      781 acaaggtgct ggcctcgaac acctatcttc caggacctcc tggcctgcct gggggacagg
      841 gcccacctgg ctcaccagga cccaagggga gccctggatt ccccggtatg ccaggccctc
      901 ctggacaacc aggcccacgg ggctcaatgg gacctatggg accatcccct gacctgtctc
      961 atattaagca aggccggagg ggccctgtgg gtccaccagg agcaccagga agacatggct
     1021 tgaaggggga gagaggagca cctgggcccc cagggtctcc gggaccccca ggttcttttg
     1081 acttcctgct gctggtactg gcggacattc gaaatgatat cgcagagcta caggagaaag
     1141 tgtttggaca tcggattcac tcttctgcag aggacttccc cctacctcag gaattctcca
     1201 gctacccaga gaccctggac tttgggtctg gagatgacta ttccagaaga actgaagcaa
     1261 gggactctga ggccccgaga aacttttatc catagcacat cccatatctt caagccacca
     1321 gaagagaagc ttgccttcgt ccttcccctt actcggtttc caaaccctgc cttctaagtt
     1381 tccttcgcat cacaacagca gcaggaggat gtgatgggtt gacatgctgt tcttgaagag
     1441 ccaatgggtg gttaacatca aggctttctt tagcatccta ctttttcaag aacctttgga
     1501 attctgagtt aatcgctccc accgaatctt aaacgttggt agagtgcaag agagggagaa
     1561 atggcaacat gggttcttag aagtgtaagg ttccttctaa aaagaaaatg atgttcaagt
     1621 acttgactgt tcattctcta ctgtccagag taaggctttt cagttgtgga ggaatggggt
     1681 gtggaaggag caaccacgta aaatgacatt ggtggaaaat tacttttctt atcaatgtca
     1741 cagatttcaa attctgcatc ctatttttca gcttgatgtt tgtttgtttg tttttaaatt
     1801 tgcttacaaa aaacaagaaa ttggaaagaa tatgtttgga gacatagaga attagcctta
     1861 tgtttcctgt catgtaggtt gccacatttt aaaattcaga tacgacagtc attgattcat
     1921 gcaaatccta cgtgaagaag ggagttcttt tatcgagctg gatcatgtgt tctagggggg
     1981 cttaaggtga tgaaacaccc tgtgtattct agaacagaga gctcctggag gccaggatgg
     2041 ctgaggacta tttggtcaaa agaattgtcc tgctccatac atgttgaagg tttgggaaac
     2101 aagatggctg actcctaaga agatgtacaa gacgccctag cactgatgag gtggccggat
     2161 gtgccagcag gcactcatcc aggctgaatc aaagccagag ggaagttgct ggcagggggg
     2221 acatcgagag gtgcttccgt aaatctagat ctccagaggc agatgaatct gctcttaaat
     2281 ctgaagtcct tatccagggc cagccagggc cagccaggct caccagcagt tggaatagca
     2341 cacagctgag aggtctctgg gatagagaag gaggagattt tactaacttg gaataatttc
     2401 ccactatttc cccctgtctt gatttaaatc cctgttgttc taggtctcct tgactttctg
     2461 tcacatttcc caatgtctcc ctgagttgtt tctgggagta cttctagatc cccagggaat
     2521 cacattccca gaaaggaaca agaggccagc aggtttcttc ttgctgtctc tgggtttttg
     2581 tttcagggat cgactatcac tttctccttg agtgtgcagt atgctccttg accttgctca
     2641 catggttgcc cacaccaggg tctctgtttg ctctcctgca gcatcccttt atatttctaa
     2701 gaagttttgc gcttgtattt atcttttccc tataccacct aagcctccat tttcttccca
     2761 cccctactgt gacagcttgt tggaagaaaa ctgctattgg tgtgcatgac actgtaccat
     2821 ccactcttct ttctgagcaa tgagaagggg ctgctacaga gccagcggga gcctagtggc
     2881 ctttcacttc cccttcccca gctccctacc ctctcatcct tctctcctgg ctctcttccc
     2941 tttcctctct tttctctctt cctctcctct tcctttgccc cttctctcct tcctttcctt
     3001 tatccctatc ctagcttccc tgcctttctc tctctctaca tctcccttca attctcttgc
     3061 atgtctcctt ccttcctctc tccctcactc tcccgctctc cctcctcttt ccttccttag
     3121 ttccctccct ccacttcccc cttccttcct acctacttac gtgcttccct ttttccttcc
     3181 ttagttccct ctctccactc cctcccttct tccctgcttg cctgcctatc ttcctatcct
     3241 gcaggattcc cacacactcc caccaaagtc accaatggct gtccaccaac agttcacggc
     3301 gaaggcaagc acacacttgc attactcgct cgctgtctct ccctccttcc ctgtcagtct
     3361 ctccagaacc tgagcatcac cacagatggc cttgccaacc atggcttcct gaagagatag
     3421 atgcaaccac agtcaagcgc cacctggaat ctattcagtg cttgcctgct tatagagccc
     3481 gtcacttaaa gggtgtgggt ggatgaattc tcaaaactat gcacaggctc tgtgagcaat
     3541 gattatgtcc atcttggttt tttatgagga attttataac tactttttat gtctactttt
     3601 tttttagaca gtgaaatgta tgtagaacta taatctttat tgccaagtgc tggtaaaatg
     3661 caagtacact ccatgcttgg ctggaggcca gggttatgtc ctaaaggagg gaagtgaaag
     3721 tcacaatatc tgggattcat gagtctgtct aggtaattat ctcccggaaa acataatagc
     3781 ctgtatcttg taacctcagt gctcatatgc catgtcaatt tagataattg ttactcctca
     3841 gattttcaaa acgtggacta ctaactaact ataagaccag ggcatgtcct ccaattgtcc
     3901 aaacaatgga tttttagcga ttaggtatta ttgcttacat atcttttagt cgtggataga
     3961 aaaatcaaag cttttctgtc taaacaaact tctgctcaaa atgccatgga aaggccttca
     4021 gatttactga gtcacttcta tctcatgggg aaaatgttct cgttttttat acacccttca
     4081 accctttggt aaaaacattc aacttttcta atatctcccc aagttaagac ttggtaatgg
     4141 attgcctctg tgtttgtaaa gccatgagaa ttaaaaattc actgaaaata atatagagaa
     4201 gacttgcatt ttagttcagg aaaaccaaat tttctagctg cagagggaaa aataatcagc
     4261 gttcctgtgc cagataaagg ttaggtgtgg tggacgcctg taatcccagc acctgagaag
     4321 cagaggtagg cagatcggga gttcaaggtc aacctcagct acaagtgtga ggccagcctg
     4381 ggctaactga gagcctatct caaagtgatg atgatgatga tgatgatgat gatgatgatg
     4441 atgatgatga tgatatgata acaaataata ataattagta ggactggaga gatggctcag
     4501 aggttaagga tgcttgctgc tcttccagaa gcgaagttca gtttctagct cctgcatcat
     4561 acagctcaaa gactccccta accccatgtc cagttgatct gacgccctct tctgacttcc
     4621 atagcacctg cactcatgtg cgcacacaca gggacacaca tacacataat tataaataaa
     4681 gtcttttttt aaaggagttg ggtaccaaga agatgctgcc ttttcttgct ttctatgtta
     4741 ctttcctata cttgctacag aattaactag agtcatattg ctgtgtggag tcagtccagt
     4801 gtccagcagg aagataataa gtgcccaatg accttggaag gaagaagtac tggccccatc
     4861 aatggctggg tgcagagcac cctggtagag ccaggtaagt catgttccct ttccaaggtt
     4921 ccaaacattg ttggccttgg aagtttgact atctcgcatg ttgggacaga gcttcttcat
     4981 gaccaagcat caaactttac cttgaggtct caggaaacaa ccctctatct tgttttaagc
     5041 atcattttcc tcctcttctc ttatccatcc aggctgcctc acagaagcag cctcagcagc
     5101 ctccttctgc aagcctatct tccagacaac tgttctaaaa gggaaaacta tagactggaa
     5161 tctgagccaa acaattagtc aaatagagac ttctattcag ggaaacgcat gggtcgtttc
     5221 ctgacacagt catcatgcat ggttcacgac atgtcaaaaa taattttcta tttggatttt
     5281 tctaaaaggg ccttaattgt tgaaactgaa atggtgcgct ttatatgctc tttgtacaaa
     5341 tgtcaccatc agcgagaaac catggagaag gacgtatggg ctatacatcc ctcagggagc
     5401 tcagcatgtt ttgtccgatt cccagagctt gttccctgag tggttcttga gtctgttttt
     5461 gttttgtttc tcagtaactg gtcatatact tcagtatctc tgtccgttat ttatatcatg
     5521 tcttataaga gtcaaactga taattccaac agtcatggat gtaatactat gaagtgtgta
     5581 atagtatgac tgtataatgc ctaataacaa agttattttt ctta
//
