LOCUS       NP_001102005            1148 aa            linear   ROD 18-NOV-2024
DEFINITION  cell division cycle and apoptosis regulator protein 1 isoform 1
            [Rattus norvegicus].
ACCESSION   NP_001102005 XP_001058761 XP_001058883 XP_342144
VERSION     NP_001102005.1
DBSOURCE    REFSEQ: accession NM_001108535.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 1148)
  AUTHORS   Mizuta,S., Minami,T., Fujita,H., Kaminaga,C., Matsui,K., Ishino,R.,
            Fujita,A., Oda,K., Kawai,A., Hasegawa,N., Urahama,N., Roeder,R.G.
            and Ito,M.
  TITLE     CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a
            novel pathway for GATA1 function
  JOURNAL   Genes Cells 19 (1), 28-51 (2014)
   PUBMED   24245781
  REMARK    Erratum:[Genes Cells. 2023 Jan;28(1):78. doi: 10.1111/gtc.12991.
            PMID: 36647803]
REFERENCE   2  (residues 1 to 1148)
  AUTHORS   Seo,W.Y., Jeong,B.C., Yu,E.J., Kim,H.J., Kim,S.H., Lim,J.E.,
            Kwon,G.Y., Lee,H.M. and Kim,J.H.
  TITLE     CCAR1 promotes chromatin loading of androgen receptor (AR)
            transcription complex by stabilizing the association between AR and
            GATA2
  JOURNAL   Nucleic Acids Res 41 (18), 8526-8536 (2013)
   PUBMED   23887938
REFERENCE   3  (residues 1 to 1148)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (residues 1 to 1148)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (residues 1 to 1148)
  AUTHORS   Kim,J.H., Yang,C.K., Heo,K., Roeder,R.G., An,W. and Stallcup,M.R.
  TITLE     CCAR1, a key regulator of mediator complex recruitment to nuclear
            receptor transcription complexes
  JOURNAL   Mol Cell 31 (4), 510-519 (2008)
   PUBMED   18722177
REFERENCE   6  (residues 1 to 1148)
  AUTHORS   Rishi,A.K., Zhang,L., Boyanapalli,M., Wali,A., Mohammad,R.M.,
            Yu,Y., Fontana,J.A., Hatfield,J.S., Dawson,M.I., Majumdar,A.P. and
            Reichert,U.
  TITLE     Identification and characterization of a cell cycle and apoptosis
            regulatory protein-1 as a novel mediator of apoptosis signaling by
            retinoid CD437
  JOURNAL   J Biol Chem 278 (35), 33422-33435 (2003)
   PUBMED   12816952
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474016.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_342144.3, XP_001058883.1, XP_001058761.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1148
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q11"
     Protein         1..1148
                     /product="cell division cycle and apoptosis regulator
                     protein 1 isoform 1"
                     /note="cell division cycle and apoptosis regulator protein
                     1; cell division cycle and apoptosis regulator protein
                     1-like"
                     /calculated_mol_wt=132023
     Region          145..201
                     /region_name="S1-like"
                     /note="pfam14444"
                     /db_xref="CDD:464176"
     Region          <184..>303
                     /region_name="PRK10927"
                     /note="cell division protein FtsN"
                     /db_xref="CDD:236797"
     Region          369..451
                     /region_name="BURAN"
                     /note="BURAN domain; pfam19257"
                     /db_xref="CDD:466013"
     Region          476..601
                     /region_name="DBC1"
                     /note="pfam14443"
                     /db_xref="CDD:464175"
     Region          634..667
                     /region_name="SAP"
                     /note="SAP domain; pfam02037"
                     /db_xref="CDD:460424"
     Region          720..787
                     /region_name="LAIKA"
                     /note="LAIKA domain; pfam19256"
                     /db_xref="CDD:466012"
     Region          921..983
                     /region_name="EF-hand_7"
                     /note="EF-hand domain pair; pfam13499"
                     /db_xref="CDD:463900"
     Region          <1036..1144
                     /region_name="HMMR_N"
                     /note="Hyaluronan mediated motility receptor N-terminal;
                     pfam15905"
                     /db_xref="CDD:464932"
     CDS             1..1148
                     /gene="Ccar1"
                     /gene_synonym="RGD1560358"
                     /coded_by="NM_001108535.1:189..3635"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="GeneID:361849"
                     /db_xref="RGD:1560358"
ORIGIN      
        1 maqfggqknp pwatqftata vsqpaalgvq qpsllgaspt iytqqtalaa aglttqtpan
       61 yqltqtaalq qqaaavlqqq ysqpqqalys vqqqlqqpqq tiltqpaval ptslslstpq
      121 paaqitvsyp tprssqqqtq pqkqrvftgv vtklhdtfgf vdedvffqlg avkgktpqvg
      181 drvlveatyn pnmpfkwnaq riqtlpnqnq sqtqpllktp taviqpivpq ttfgvqaqpq
      241 pqsllqaqis aasitpllqt qpqpllqqpq qkagllqppv rivsqpqpar rldppsrfsg
      301 rndrgdqvpn rkddrsrerd rerrrsrers pqrkrsrers prrererspr rvrrvvpryt
      361 vqfskfsldc pscdmmelrr ryqnlyipsd ffdaqftwvd afplsrpfql gnycnfyvmh
      421 revesleknv avldppdadh lysakvmlma spsmedlyhk scalaedpqd lrdgfqhpar
      481 lvkflvgmkg kdeamaiggh wspsldgpnp ekdpsvlikt aircckaltg idlsvctqwy
      541 rfaeiryhrp eethkgrtvp ahvetvvlff pdvwhclptr sewetlsrgy kqqlveklqg
      601 erkkadgeqd eeekddgevk eiatpthwsk ldpkamkvnd lrkelesral sskglksqli
      661 arltkqlkie eqkeeqkele ksekeeeded dkkseddkee eerkrqeeve rqrqerryil
      721 pdepaiivhp nwaaksgkfd csimslsvll dyrlednkeh sfevslfael fnemlqrdfg
      781 vriyksllsl pekedkkdke kkskkeerkd kkeereddid epkpkrrksg ddkdkkedrd
      841 erkkeekrkd dskdddetee dnnqdeydpm eaeeaeeeed dreeeevnkr ddkrdvsryc
      901 kdrpskdkek ekpqmvtvnr dllmafvyfd qshcgyllek dleeilytlg lhlsraqvkk
      961 llnkvvlres cfyrkltdts kdgeshdepe slqgdttlgn rlllptptvk qeskdgeenv
     1021 glivyngamv dvgsllqkle ksekvraeve qklqlleekt dedgktilnl ensnkslsge
     1081 lrevkkdlgq lqenlkvsen mnlqfenqln ktlrnlstvm ddihtvlkkd nvknedrdqk
     1141 skengssv
//
