LOCUS       NM_001106797            1190 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus chromobox 5 (Cbx5), mRNA.
ACCESSION   NM_001106797 XM_001069676 XM_217062
VERSION     NM_001106797.3
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Gilmore,J.M., Sardiu,M.E., Groppe,B.D., Thornton,J.L., Liu,X.,
            Dayebgadoh,G., Banks,C.A., Slaughter,B.D., Unruh,J.R.,
            Workman,J.L., Florens,L. and Washburn,M.P.
  TITLE     WDR76 Co-Localizes with Heterochromatin Related Proteins and
            Rapidly Responds to DNA Damage
  JOURNAL   PLoS One 11 (6), e0155492 (2016)
   PUBMED   27248496
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1190)
  AUTHORS   Patel,D.J. and Wang,Z.
  TITLE     Readout of epigenetic modifications
  JOURNAL   Annu Rev Biochem 82, 81-118 (2013)
   PUBMED   23642229
  REMARK    Review article
REFERENCE   3  (bases 1 to 1190)
  AUTHORS   Whelan,G., Kreidl,E., Wutz,G., Egner,A., Peters,J.M. and Eichele,G.
  TITLE     Cohesin acetyltransferase Esco2 is a cell viability factor and is
            required for cohesion in pericentric heterochromatin
  JOURNAL   EMBO J 31 (1), 71-82 (2012)
   PUBMED   22101327
REFERENCE   4  (bases 1 to 1190)
  AUTHORS   Yu,Y.H., Chiou,G.Y., Huang,P.I., Lo,W.L., Wang,C.Y., Lu,K.H.,
            Yu,C.C., Alterovitz,G., Huang,W.C., Lo,J.F., Hsu,H.S. and
            Chiou,S.H.
  TITLE     Network biology of tumor stem-like cells identified a regulatory
            role of CBX5 in lung cancer
  JOURNAL   Sci Rep 2, 584 (2012)
   PUBMED   22900142
REFERENCE   5  (bases 1 to 1190)
  AUTHORS   Rosnoblet,C., Vandamme,J., Volkel,P. and Angrand,P.O.
  TITLE     Analysis of the human HP1 interactome reveals novel binding
            partners
  JOURNAL   Biochem Biophys Res Commun 413 (2), 206-211 (2011)
   PUBMED   21888893
REFERENCE   6  (bases 1 to 1190)
  AUTHORS   Nielsen,A.L., Ortiz,J.A., You,J., Oulad-Abdelghani,M.,
            Khechumian,R., Gansmuller,A., Chambon,P. and Losson,R.
  TITLE     Interaction with members of the heterochromatin protein 1 (HP1)
            family and histone deacetylation are differentially involved in
            transcriptional silencing by members of the TIF1 family
  JOURNAL   EMBO J 18 (22), 6385-6395 (1999)
   PUBMED   10562550
REFERENCE   7  (bases 1 to 1190)
  AUTHORS   Remboutsika,E., Lutz,Y., Gansmuller,A., Vonesch,J.L., Losson,R. and
            Chambon,P.
  TITLE     The putative nuclear receptor mediator TIF1alpha is tightly
            associated with euchromatin
  JOURNAL   J Cell Sci 112 (Pt 11), 1671-1683 (1999)
   PUBMED   10318760
REFERENCE   8  (bases 1 to 1190)
  AUTHORS   Lehming,N., Le Saux,A., Schuller,J. and Ptashne,M.
  TITLE     Chromatin components as part of a putative transcriptional
            repressing complex
  JOURNAL   Proc Natl Acad Sci U S A 95 (13), 7322-7326 (1998)
   PUBMED   9636147
REFERENCE   9  (bases 1 to 1190)
  AUTHORS   Seeler,J.S., Marchio,A., Sitterlin,D., Transy,C. and Dejean,A.
  TITLE     Interaction of SP100 with HP1 proteins: a link between the
            promyelocytic leukemia-associated nuclear bodies and the chromatin
            compartment
  JOURNAL   Proc Natl Acad Sci U S A 95 (13), 7316-7321 (1998)
   PUBMED   9636146
REFERENCE   10 (bases 1 to 1190)
  AUTHORS   Le Douarin,B., Nielsen,A.L., Garnier,J.M., Ichinose,H.,
            Jeanmougin,F., Losson,R. and Chambon,P.
  TITLE     A possible involvement of TIF1 alpha and TIF1 beta in the
            epigenetic control of transcription by nuclear receptors
  JOURNAL   EMBO J 15 (23), 6701-6715 (1996)
   PUBMED   8978696
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166908.1.
            
            On Aug 30, 2012 this sequence version replaced NM_001106797.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166908.1, FM071446.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMN09767679
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1190              BC166908.1         2-1191
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..1190
                     /gene="Cbx5"
                     /note="chromobox 5"
                     /db_xref="GeneID:300266"
                     /db_xref="RGD:1306619"
     exon            1..43
                     /gene="Cbx5"
                     /inference="alignment:Splign:2.1.0"
     exon            44..143
                     /gene="Cbx5"
                     /inference="alignment:Splign:2.1.0"
     exon            144..326
                     /gene="Cbx5"
                     /inference="alignment:Splign:2.1.0"
     CDS             190..765
                     /gene="Cbx5"
                     /note="chromobox homolog 5 (HP1 alpha homolog,
                     Drosophila)"
                     /codon_start=1
                     /product="chromobox protein homolog 5"
                     /protein_id="NP_001100267.1"
                     /db_xref="GeneID:300266"
                     /db_xref="RGD:1306619"
                     /translation="MGKKTKRTADSSSSEDEEEYVVEKVLDRRMVKGQVEYLLKWKGF
                     SEEHNTWEPEKNLDCPELISEFMKKYKKMKEGENNKPREKSEGNKRKSSFSNSADDIK
                     SKKKREQSNDIARGFERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKC
                     PQIVIAFYEERLTWHAYPEDAENKEKESAKS"
     exon            327..513
                     /gene="Cbx5"
                     /inference="alignment:Splign:2.1.0"
     exon            514..614
                     /gene="Cbx5"
                     /inference="alignment:Splign:2.1.0"
     exon            615..1162
                     /gene="Cbx5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcccagagg gaaagaacga actggggcga tccggtaggt aagggaaggc catagccaca
       61 atgcttaact gcatgcttcc aacatggggc tggttttaac ccagcgctct gacctaaagt
      121 gctcagctcc cggaaattcc aaggaacctg gtggccgcac tcctttaggt ggaccaacac
      181 atacccaaca tgggaaagaa gaccaagagg acagccgaca gctcttcatc agaggatgag
      241 gaggagtatg tggtggaaaa ggtgttggac aggcgcatgg ttaaagggca agtggagtat
      301 ctgctgaagt ggaaaggctt ttctgaggag cacaacactt gggaacctga gaagaacttg
      361 gattgtcctg aactaatttc tgagtttatg aaaaagtaca agaagatgaa ggagggagag
      421 aacaacaagc ctagggagaa gtcagaagga aacaagagga aatccagttt ttccaacagt
      481 gctgatgata ttaaatccaa aaaaaagaga gagcaaagca atgatatcgc tcggggcttt
      541 gagagaggac tggaaccaga aaagatcatt ggggcgacag attcctgtgg agacttaatg
      601 ttcttaatga aatggaaaga cacagatgaa gctgacctgg tccttgcaaa agaagctaat
      661 gtgaaatgtc cacaaattgt gatagcattt tatgaagaga gactgacgtg gcatgcgtat
      721 ccagaggatg cggaaaacaa agaaaaagaa agcgcaaaga gctaaaggag gaggcagtct
      781 ctgtcatttc tctttgtata taataccttc accttcctgc ctcctctcgc ttctcccgtc
      841 cctttccatc ctaaacatat ccataaaaat gatgtgctta tcaatcactg tgctccacgg
      901 gagagatgtt ggtattggtt cccttgtaat ataactgatg gtctgactcc taagtgtagc
      961 tctgtgaaag tcaggcatta catccttcac atgctgtgtg gttcccatag tgttctcttt
     1021 catcctgatc ttttccttct gttccctgta acttttaatc accttagagt cgtgatcttt
     1081 ggggttggtt gctttgggga attttattat aatgacgatg acttcagttt cttggttgtt
     1141 aattagaata tattgatgac caaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
