LOCUS       NM_001398806            1445 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus chromobox 1 (Cbx1), mRNA.
ACCESSION   NM_001398806 XM_006247235
VERSION     NM_001398806.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1445)
  AUTHORS   Gilmore,J.M., Sardiu,M.E., Groppe,B.D., Thornton,J.L., Liu,X.,
            Dayebgadoh,G., Banks,C.A., Slaughter,B.D., Unruh,J.R.,
            Workman,J.L., Florens,L. and Washburn,M.P.
  TITLE     WDR76 Co-Localizes with Heterochromatin Related Proteins and
            Rapidly Responds to DNA Damage
  JOURNAL   PLoS One 11 (6), e0155492 (2016)
   PUBMED   27248496
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1445)
  AUTHORS   Grolimund,L., Aeby,E., Hamelin,R., Armand,F., Chiappe,D.,
            Moniatte,M. and Lingner,J.
  TITLE     A quantitative telomeric chromatin isolation protocol identifies
            different telomeric states
  JOURNAL   Nat Commun 4, 2848 (2013)
   PUBMED   24270157
REFERENCE   3  (bases 1 to 1445)
  AUTHORS   Qin,J., Whyte,W.A., Anderssen,E., Apostolou,E., Chen,H.H.,
            Akbarian,S., Bronson,R.T., Hochedlinger,K., Ramaswamy,S.,
            Young,R.A. and Hock,H.
  TITLE     The polycomb group protein L3mbtl2 assembles an atypical
            PRC1-family complex that is essential in pluripotent stem cells and
            early development
  JOURNAL   Cell Stem Cell 11 (3), 319-332 (2012)
   PUBMED   22770845
REFERENCE   4  (bases 1 to 1445)
  AUTHORS   Bronze-da-Rocha,E., Lin,C.M., Shimura,T. and Aladjem,M.I.
  TITLE     Interactions of MCP1 with components of the replication machinery
            in mammalian cells
  JOURNAL   Int J Biol Sci 7 (2), 193-208 (2011)
   PUBMED   21383955
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1445)
  AUTHORS   Souza,P.P., Volkel,P., Trinel,D., Vandamme,J., Rosnoblet,C.,
            Heliot,L. and Angrand,P.O.
  TITLE     The histone methyltransferase SUV420H2 and Heterochromatin Proteins
            HP1 interact but show different dynamic behaviours
  JOURNAL   BMC Cell Biol 10, 41 (2009)
   PUBMED   19486527
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1445)
  AUTHORS   Bozhenok,L., Wade,P.A. and Varga-Weisz,P.
  TITLE     WSTF-ISWI chromatin remodeling complex targets heterochromatic
            replication foci
  JOURNAL   EMBO J 21 (9), 2231-2241 (2002)
   PUBMED   11980720
  REMARK    Erratum:[EMBO J 2002 Jun 17;21(12):3212]
REFERENCE   7  (bases 1 to 1445)
  AUTHORS   Kourmouli,N., Theodoropoulos,P.A., Dialynas,G., Bakou,A.,
            Politou,A.S., Cowell,I.G., Singh,P.B. and Georgatos,S.D.
  TITLE     Dynamic associations of heterochromatin protein 1 with the nuclear
            envelope
  JOURNAL   EMBO J 19 (23), 6558-6568 (2000)
   PUBMED   11101528
REFERENCE   8  (bases 1 to 1445)
  AUTHORS   Brasher,S.V., Smith,B.O., Fogh,R.H., Nietlispach,D., Thiru,A.,
            Nielsen,P.R., Broadhurst,R.W., Ball,L.J., Murzina,N.V. and
            Laue,E.D.
  TITLE     The structure of mouse HP1 suggests a unique mode of single peptide
            recognition by the shadow chromo domain dimer
  JOURNAL   EMBO J 19 (7), 1587-1597 (2000)
   PUBMED   10747027
REFERENCE   9  (bases 1 to 1445)
  AUTHORS   Nielsen,A.L., Ortiz,J.A., You,J., Oulad-Abdelghani,M.,
            Khechumian,R., Gansmuller,A., Chambon,P. and Losson,R.
  TITLE     Interaction with members of the heterochromatin protein 1 (HP1)
            family and histone deacetylation are differentially involved in
            transcriptional silencing by members of the TIF1 family
  JOURNAL   EMBO J 18 (22), 6385-6395 (1999)
   PUBMED   10562550
REFERENCE   10 (bases 1 to 1445)
  AUTHORS   Wreggett,K.A., Hill,F., James,P.S., Hutchings,A., Butcher,G.W. and
            Singh,P.B.
  TITLE     A mammalian homologue of Drosophila heterochromatin protein 1 (HP1)
            is a component of constitutive heterochromatin
  JOURNAL   Cytogenet Cell Genet 66 (2), 99-103 (1994)
   PUBMED   8287692
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Dec 23, 2021 this sequence version replaced XM_006247235.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.63505.1,
                                           SRR26643429.38631.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-221               JAXUCZ010000010.1  82266762-82266982
            222-398             JAXUCZ010000010.1  82279938-82280114
            399-576             JAXUCZ010000010.1  82280630-82280807
            577-671             JAXUCZ010000010.1  82281720-82281814
            672-1445            JAXUCZ010000010.1  82285658-82286431
FEATURES             Location/Qualifiers
     source          1..1445
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..1445
                     /gene="Cbx1"
                     /note="chromobox 1"
                     /db_xref="GeneID:360609"
                     /db_xref="RGD:1310714"
     exon            1..221
                     /gene="Cbx1"
                     /inference="alignment:Splign:2.1.0"
     exon            222..398
                     /gene="Cbx1"
                     /inference="alignment:Splign:2.1.0"
     CDS             259..816
                     /gene="Cbx1"
                     /note="chromobox homolog 1 (HP1 beta homolog Drosophila)"
                     /codon_start=1
                     /product="chromobox protein homolog 1"
                     /protein_id="NP_001385735.1"
                     /db_xref="GeneID:360609"
                     /db_xref="RGD:1310714"
                     /translation="MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKG
                     FSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKSDGGKRKADSDSEDKGEESKPKK
                     KKEESEKPRGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVV
                     ISFYEERLTWHSYPSEDDDKKDDKN"
     exon            399..576
                     /gene="Cbx1"
                     /inference="alignment:Splign:2.1.0"
     exon            577..671
                     /gene="Cbx1"
                     /inference="alignment:Splign:2.1.0"
     exon            672..1445
                     /gene="Cbx1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctgcgcagt gcaggcggcg ggccgcgcag agtgagaatc tcttttgttc ggctgagggg
       61 agggccgttg gccgggcctg cggtacgccg cttcatctgg acgaccgact tgaggccaca
      121 cggctgtttg ctcctctggg tgctactccc tgggaccgcc tgacgcaacg cgcaagaagc
      181 gcgacaccga ttcctctcgg actgtcgggc gctgctacga gcagtgtcac ccttcacacc
      241 agaaagctgg cgggtactat ggggaaaaag caaaacaaaa agaaagtgga agaggtacta
      301 gaagaagagg aagaggaata tgtggtggaa aaagttcttg atcggcgagt tgtcaagggc
      361 aaggtggaat atcttctaaa gtggaaaggt ttctcagatg aggacaacac ttgggagcca
      421 gaagagaatc tggattgccc tgaccttatt gctgagtttc tacagtccca gaagacagct
      481 catgagacgg ataaatcaga cggaggcaag cgcaaagctg attctgattc tgaagataaa
      541 ggagaggaaa gcaaaccaaa gaagaagaaa gaagagtcag aaaagccacg aggctttgcc
      601 cggggtctgg agccagagcg gattattgga gctactgact ccagtggaga gctcatgttc
      661 ctgatgaaat ggaaaaactc tgatgaggct gacctggtcc ctgccaagga agccaatgtc
      721 aagtgcccac aggttgtcat atccttctat gaggaaaggc taacgtggca ttcctacccc
      781 tcagaggatg atgacaaaaa agacgacaag aattagccct gttgagtacc agcccctgtc
      841 acctctgact gtgggtttcc agggggaggg aaggagctgt acttgtcttg acaccattga
      901 ggtggcttga gaagatgtcc tttgaagagc cagcatagtt tctgtgtcct gcagcagccc
      961 aagtgcttta aattgttcac actgtatagt ttgcacaccc atcccagggg aggggaaagg
     1021 gtaagtgttt caaggctctg ttctgcgctt tactaaggaa ggaacaggcc ttccatggag
     1081 gacagaaccc gcagaactgg gatgtgggaa agcaaagata ctgtcgatct tcaaagagca
     1141 tctccacaac ccactgcctt cttcccaata gtgttaactg catttttaca gcctagcatg
     1201 tgtgtagttt tttggctatt actggtatat taattggggg tgggagggtt ggggcaggga
     1261 ggaagggaga tgggtagaat cattttgatt aaaatttgga gcctgattgg ggaaatggtg
     1321 aaacagtaga acagttaact aataaattgg ttctatgtcc agaatatttt gccttttcaa
     1381 aaaattgtca ttggcaccat aaataaggac tatgagagac tgtttaaaaa aaaaaaaaag
     1441 aaaag
//
