LOCUS       XM_003750987            3081 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus carbonyl reductase 2 (Cbr2), mRNA.
ACCESSION   XM_003750987
VERSION     XM_003750987.5
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051345.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_003750987.6.
            
            On Jan 21, 2021 this sequence version replaced XM_003750987.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3081
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3081
                     /gene="Cbr2"
                     /note="carbonyl reductase 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 15
                     Proteins, and 92% coverage of the annotated genomic
                     feature by RNAseq alignments"
                     /db_xref="GeneID:688320"
                     /db_xref="RGD:1590051"
     CDS             1..735
                     /gene="Cbr2"
                     /codon_start=1
                     /product="carbonyl reductase [NADPH] 2"
                     /protein_id="XP_003751035.1"
                     /db_xref="GeneID:688320"
                     /db_xref="RGD:1590051"
                     /translation="MKLNFSGLRALVTGAGKGIGRDTAKALHASGAKVVAVTRTNADL
                     VSLAKECPGIEPVCVDLGDWEATEKALGGIGPVDLLVNNAALVIMQPFLEITKEAFDR
                     SFSVNLRSVFQVSQMVARDMINRGVAGSIVNVSRIVAHVTFPNLTTYSSTKGAMTMLT
                     KAMAMELGPHKIRVNSVNPTVVLTDMGKKVSADPDLARKFKERHPLRKFAEVEDVVNS
                     ILFLLSDSSASTSGSGILVDSGYLAS"
ORIGIN      
        1 atgaagttga atttcagtgg cctgagggcc ctggtgacag gggcagggaa agggattggg
       61 cgtgacactg cgaaggccct gcatgcctca ggagccaaag tggtggccgt gacgcgaacc
      121 aatgcagacc tggtcagcct tgccaaggaa tgtcctggga tagagcccgt gtgtgtggac
      181 ctgggtgact gggaggccac agagaaggcg ctgggcggta tcggccctgt ggacttgcta
      241 gtgaacaatg cagccctggt tataatgcag cccttcctgg aaattaccaa ggaagccttt
      301 gacaggtcct tcagtgtaaa ccttcgctct gtgtttcagg tatcccagat ggtagccagg
      361 gacatgatta accgtggagt ggcagggtcc attgtcaacg tctccagaat agttgctcac
      421 gttacctttc ctaacttgac cacctacagc tctaccaagg gagcaatgac tatgctgacc
      481 aaagccatgg ccatggaact ggggccgcac aagatccggg tgaactctgt aaatcccact
      541 gtggtgctga ctgacatggg caagaaagtc tctgcagacc ctgacttggc caggaagttc
      601 aaggagcgcc acccactgag gaagttcgca gaggttgagg acgtagtcaa cagcattctc
      661 tttctgctca gcgacagcag tgcctctacc agtggctctg gcatcctggt ggactctggc
      721 tacctggcct cctagtctgc ctagataccg cggacctctg agtggccttc ctggccccac
      781 tctcagccaa agcttcaact gatctccaga ccccgccctc atgccacagc cacgcccccc
      841 acgcatctcg ccaggttcgc actcatgtta ttgtctgatc ccacaaccac tccaggctcc
      901 tgaccttgga gttgtgttct ctttgcccgc tttgttgggc tcgtttgcct aaataaatgg
      961 gccaccatgt caccgtaacc attgcacagg actctttcgg gggtaggggt ggccctttgc
     1021 aaagctggat gctgaatcaa gtcccgcctg caggcatttc acctcgaagc ctgctatcct
     1081 ccaatacctc ctgtgtcttg tgaccaatgt gaccaaagga cagtggttct tctcaaaaga
     1141 aaagatctat atcgttgtgc cctttcccct cgtgcccgca cctcttcagt cctggatctg
     1201 ttgcctcttg gctctctgac ccggaccccg caatcgtggg aagggaacgg gaggtattct
     1261 ggaccaggtt actccttagc ccgtggactc tgtgcagaag gagaggagat gttgggtggg
     1321 gatcagaatc atgccttctt ctctggggag cccacttccc tggccggatt cacacatgag
     1381 accgtgctaa gaaagctacc caaatgggcg gaagttttca cagctagcta gctgcactat
     1441 caccctagcc tgaaccagca cagtaatcct gcaacccaga ctcctcagag agccttggag
     1501 gcctggcagg ttctcacgtg gttgcttaca ttggcccaag gtatcttgta gtctgttggg
     1561 cctgaggcgg ccaaccattt gaattgacat gaggtccctc tcagggcaag tggcagagtg
     1621 gaggaggatg tgctcagtta agacctttaa agagagcaca ggacacaggt tccgagagca
     1681 cttctctcca gagagcaagg cctgagcagc ctcacgcacc caggaccaca gaacaatgca
     1741 caagatttgt acacgtccta agaaacagac ccactaaggc gttctaagca gctgtgccta
     1801 ggcgtcgggc agactggctc tgtctcctgg tttctggcag ggaactggca gagttcaagg
     1861 ttaggagagg atggcagtgt tcacagaatg gcctcacagt ggtggcaagc cggtcaaaac
     1921 tgcggaggga acactcacct gcctattctc ccgcttcttt tctttccatg gtttttataa
     1981 aattactgtg atttttttgt gtctgggttt ttgtctgcct gtatgtctgt gcaccacgtg
     2041 tatgcccata cggaccaaaa gagggcatgg gttgccctag agcagatggt tgtgggctgc
     2101 catatgggtg ttgaggatca aacccaagtc ctttggaact gcacccagtg cttttagcca
     2161 ctgagcctcc tgcagttgac tttcaaaaca ctcagcccat ggacttgcct ctctgggccc
     2221 aaagccccac atcactcagg gctctgcaat caccagatcc ctactactgg ccagagtaga
     2281 tcctcagagc aattgctttg gtcttcctca ccacgactct aaaaacaaga tacattttaa
     2341 aaaatatttt atttatttaa tgtatatgag tacattgtag ctgtctcgag atacaccaga
     2401 atctgttaca gatggttgtg agccatcatg tagttgctgg gaattgaacc caggatctct
     2461 gaaagagcag tcagtgctct tagccactga gccatctttc cagcccccca aacaagatat
     2521 ttttataagg agacccagtg cacacctgga cattaatctg caactgactc ttaagccttg
     2581 aaaagcagca tttgtctggc cagttctcat gtaaatctcc aaacccaatc caacctctta
     2641 ttgtctagtg accaccggat acaagttgga taaggtgacc ttgggtctta gcttttatgt
     2701 taatttgggg atttactgat aacagtgtct tcttcggact tatccggatg cccgattttt
     2761 tttttttcaa gacagggttt ctctgtgtag ccagactgac ttggaacttg ctctgtagtc
     2821 caagctggcc ttgaattttg agagatctgc ctgcctccgc ctcccgagtg ctgggattaa
     2881 agtgtgtgtc gttaccattc agtttggatg tccacctctc cctgtctggg tattacatat
     2941 ggaccattgc aacacactcc tgggcctggg gaaaaaagac atagaaacgt ttttggacaa
     3001 gtctctcagg ttcacgagta tccatgaaac tcctgtaata attactatgt tttagtggaa
     3061 atcttagtag tagaaaccat g
//
