LOCUS       NM_001109210            2903 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus cerebellin 4 precursor (Cbln4), mRNA.
ACCESSION   NM_001109210 XM_001053640 XM_575292
VERSION     NM_001109210.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2903)
  AUTHORS   Favuzzi E, Deogracias R, Marques-Smith A, Maeso P, Jezequel J,
            Exposito-Alonso D, Balia M, Kroon T, Hinojosa AJ, F Maraver E and
            Rico B.
  TITLE     Distinct molecular programs regulate synapse specificity in
            cortical inhibitory circuits
  JOURNAL   Science 363 (6425), 413-417 (2019)
   PUBMED   30679375
REFERENCE   2  (bases 1 to 2903)
  AUTHORS   Rong Y, Bansal PK, Wei P, Guo H, Correia K, Parris J and Morgan JI.
  TITLE     Glycosylation of Cblns attenuates their receptor binding
  JOURNAL   Brain Res 1694, 129-139 (2018)
   PUBMED   29782851
REFERENCE   3  (bases 1 to 2903)
  AUTHORS   Chacon PJ, del Marco A, Arevalo A, Dominguez-Gimenez P,
            Garcia-Segura LM and Rodriguez-Tebar A.
  TITLE     Cerebellin 4, a synaptic protein, enhances inhibitory activity and
            resistance of neurons to amyloid-beta toxicity
  JOURNAL   Neurobiol Aging 36 (2), 1057-1071 (2015)
   PUBMED   25534236
REFERENCE   4  (bases 1 to 2903)
  AUTHORS   Iijima T, Miura E, Matsuda K, Kamekawa Y, Watanabe M and Yuzaki M.
  TITLE     Characterization of a transneuronal cytokine family
            Cbln--regulation of secretion by heteromeric assembly
  JOURNAL   Eur J Neurosci 25 (4), 1049-1057 (2007)
   PUBMED   17331201
REFERENCE   5  (bases 1 to 2903)
  AUTHORS   Bao D, Pang Z, Morgan MA, Parris J, Rong Y, Li L and Morgan JI.
  TITLE     Cbln1 is essential for interaction-dependent secretion of Cbln3
  JOURNAL   Mol Cell Biol 26 (24), 9327-9337 (2006)
   PUBMED   17030622
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474062.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_575292.2, XM_001053640.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ101311.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760396
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2903
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..2903
                     /gene="Cbln4"
                     /note="cerebellin 4 precursor"
                     /db_xref="GeneID:499947"
                     /db_xref="RGD:1589642"
     exon            1..1453
                     /gene="Cbln4"
                     /inference="alignment:Splign:2.1.0"
     CDS             1172..1768
                     /gene="Cbln4"
                     /note="cerebellin-4; cerebellin 4 precursor protein"
                     /codon_start=1
                     /product="cerebellin-4 precursor"
                     /protein_id="NP_001102680.1"
                     /db_xref="GeneID:499947"
                     /db_xref="RGD:1589642"
                     /translation="MGSARRALSVVPAVLLVLVLPVWAQNDTEPIVLEGKCLVVCDSN
                     PATDSKGSSSSPLGISVRAANSKVAFSAVRSTNHEPSEMSNKTRIIYFDQILVNVGNF
                     FTLESVFVAPRKGIYSFSFHVIKVYQSQTIQVNLMLNGKPVISAFAGDKDVTREAATN
                     GVLLYLDKEDKVYLKLEKGNLLGGWQYSTFSGFLVFPL"
     exon            1454..1570
                     /gene="Cbln4"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..2903
                     /gene="Cbln4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acaaaccgcg cagatccgcc gcggtccttt catctccaca tctgagctgg cagcgccacg
       61 ttcggttcag agagtcttgc gcagggcagg gtgaggggac ccacaactcc ctctgcgggt
      121 ccaggtggag ctggcggcaa gcagccgtga agccgtggca ggcgcgttcc ggtgggcacc
      181 atcctctgcg cacacacagt gagatttcgg gggaccaagt ggcctcggac ctggcagcag
      241 gcagtgccgt gtgtccttct cggtccgtgt gcgttcaacg tcacacaggc gctgctccgc
      301 tggggtcacc ggacgccttt tctgctttcc ggggatccgc gggatggtcg agcgagccaa
      361 agccatctgc aggcagcact cctataaata gcgggcgggt gccctctcgg cgctctccct
      421 cccggctgca ctgcgcgctg agacacaaag ttgtgcacag ggacgaggga acccagggta
      481 gccggcgccc tgaaccttag aactgctttt ggcgaccggc attcagctga gccgcctacc
      541 tgcgtcggag tgacaccggg ctttggggga atttttggct atttttgggg gagtcgctag
      601 catcctggac atggacacaa cctggcgttc ttctcatccc cggaaacacc tcctgcctct
      661 gtaatttgtt cctgcgccaa ccagagtccc tcagaccgga ccgacacccg cactgctcct
      721 cactagccac cctagctagc gtttacttgc tgagtcccca ctgtgtcttc agctccgtgc
      781 ttctctaaga gtgcttgggg tttggggtga ggatttattt tgttcttttg cggtgtgacc
      841 gagagggcct cgagactttt tagatgtcaa gggacaagtg tgggtgcagt ggccccaggc
      901 aaaactgatt tggggggtgg aggagttagg gtaggagttc tgcatgagct ccttaaagga
      961 caaaggtaac agagccagcc agccagctcg aagggagact tcagcccaga gaattggtga
     1021 aagtgcgcgc gccgctgctg ccgccgccgc cgctgttcct gcagcgcagt cgatctagcc
     1081 actagcctct ttcccagctc ccggatcccg gggtagcagg cgccagccgg gagcagaagc
     1141 gccaggctgc cgcttgcgca cgaggctcac catgggctcc gcgcgccggg cgctgtccgt
     1201 ggtaccagct gttctgctgg ttctcgtgct gcctgtctgg gcacagaatg acacggaacc
     1261 gatcgttctg gagggcaagt gtctggtggt gtgcgactcg aacccagcca cagactccaa
     1321 gggatcatct tcctcccctc tggggatatc ggtccgggca gcgaactcca aggtggcctt
     1381 ttcagcggtt cggagcacca accacgagcc atctgagatg agcaacaaga ctcgcatcat
     1441 ttactttgat cagatcctgg ttaacgtggg taattttttc acactggaat ccgtctttgt
     1501 ggcaccgagg aaagggatct acagtttcag ttttcacgtc attaaagtct accagagcca
     1561 aaccatccag gttaacttga tgttaaatgg aaagccagtc atctctgcat ttgccggcga
     1621 taaggacgtg acccgcgaag ccgccacgaa cggagtgcta ctgtacctgg acaaagaaga
     1681 taaggtctac ctgaaactgg agaaaggtaa cttgcttggc ggctggcagt attccacgtt
     1741 ttctggcttt ctggtgtttc cgctatagaa cctgacttct ccgtgtcgac cgagtgtgag
     1801 ggtgcccacc cccgggttgt tggaagagca ctctcggatt gatgtctctt actgttttgt
     1861 tcgtgggtga ctatggattc tctttgagaa ttctagacct gtctggacaa acacaaagtt
     1921 tcgcagatca ttttcgtgtg tgtaccagtt tcctctcatg tggaccggga ctccaaagct
     1981 gaaaaatccc taattgcttt cgtgttaact gtcagaagcc gcctcaaggt ttgttctgtt
     2041 agtttcttgc cattgcagca ttggctgcag aggtgggggg aggttttatt tctttgtttt
     2101 tgaaagactg gctagtgggt ctgaaggtta gaaaagttgt aagttctgac ttcagcggtc
     2161 atagtggaac tgccaaagac atgtggacat gtgtggatac attgattaga cttttttttt
     2221 tttaaaaaaa ctaattactt ttgaatttgt tttgttctct taaggtaact gggattgtat
     2281 tttagtgact ggcattgtgt tcactctacc cataaggtga caaatgtctt gcctcgaaac
     2341 gtcccttaac tctcagctca cccccacgac ctccctcccg ccccctaaaa cgaatgctcc
     2401 atagttgtat tttaattata tatgtgaaag agtcatattt tccaaattat attttctaat
     2461 aggaaaaaca gatcgtaaat ctgacaaaga caaagttatt taccccaatt ccaatgctca
     2521 gtcccaaacc ttggcaaagt acctctcctt ggtgggacat tgtatactct attgctcaac
     2581 tttaattaac gtgattgata ataactacct tattaaaccc accaggaatt attttctcct
     2641 tcaccgtgac cactttatta actggagatg gtgtgccctt atttttaatt gtatctattt
     2701 ttcaaatctc ctgttgtgtt tgaaatatct tctggttttg ccttaattcc ttaacttgta
     2761 tatatttttg tgttcagcta acattaaatc cagatactcc ataactaaat ttagtgcaat
     2821 atcttatttt gtcttttgta tagatcatat gaattcataa agttatttac gtctctgtta
     2881 cagaataaag attattatat gtt
//
