LOCUS       NM_001108453            2684 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus CBFA2/RUNX1 partner transcriptional co-repressor
            3 (Cbfa2t3), mRNA.
ACCESSION   NM_001108453 XM_001079414 XM_341709
VERSION     NM_001108453.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2684)
  AUTHORS   Kumar P, Gullberg U, Olsson I and Ajore R.
  TITLE     Myeloid translocation gene-16 co-repressor promotes degradation of
            hypoxia-inducible factor 1
  JOURNAL   PLoS One 10 (5), e0123725 (2015)
   PUBMED   25974097
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2684)
  AUTHORS   Kumar P, Sharoyko VV, Spegel P, Gullberg U, Mulder H, Olsson I and
            Ajore R.
  TITLE     The transcriptional co-repressor myeloid translocation gene 16
            inhibits glycolysis and stimulates mitochondrial respiration
  JOURNAL   PLoS One 8 (7), e68502 (2013)
   PUBMED   23840896
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2684)
  AUTHORS   Barrett CW, Smith JJ, Lu LC, Markham N, Stengel KR, Short SP, Zhang
            B, Hunt AA, Fingleton BM, Carnahan RH, Engel ME, Chen X, Beauchamp
            RD, Wilson KT, Hiebert SW, Reynolds AB and Williams CS.
  TITLE     Kaiso directs the transcriptional corepressor MTG16 to the Kaiso
            binding site in target promoters
  JOURNAL   PLoS One 7 (12), e51205 (2012)
   PUBMED   23251453
REFERENCE   4  (bases 1 to 2684)
  AUTHORS   Cai Y, Xu Z, Xie J, Ham AJ, Koury MJ, Hiebert SW and Brandt SJ.
  TITLE     Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL
            transcription factor in murine erythroid progenitors
  JOURNAL   Biochem Biophys Res Commun 390 (2), 295-301 (2009)
   PUBMED   19799863
REFERENCE   5  (bases 1 to 2684)
  AUTHORS   Ibanez V, Sharma A, Buonamici S, Verma A, Kalakonda S, Wang J,
            Kadkol S and Saunthararajah Y.
  TITLE     AML1-ETO decreases ETO-2 (MTG16) interactions with nuclear receptor
            corepressor, an effect that impairs granulocyte differentiation
  JOURNAL   Cancer Res 64 (13), 4547-4554 (2004)
   PUBMED   15231665
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473972.1.
            
            On or before Oct 25, 2007 this sequence version replaced
            XM_341709.3, XM_001079414.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5756307, SAMEA5760383
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2684
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..2684
                     /gene="Cbfa2t3"
                     /note="CBFA2/RUNX1 partner transcriptional co-repressor 3"
                     /db_xref="GeneID:361431"
                     /db_xref="RGD:1310547"
     exon            1..166
                     /gene="Cbfa2t3"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..1950
                     /gene="Cbfa2t3"
                     /note="translocated to, 3; core-binding factor, runt
                     domain, alpha subunit 2; translocated to, 3; CBFA2/RUNX1
                     translocation partner 3"
                     /codon_start=1
                     /product="protein CBFA2T3"
                     /protein_id="NP_001101923.1"
                     /db_xref="GeneID:361431"
                     /db_xref="RGD:1310547"
                     /translation="MSQASTTLESGALLPGPRGLHNGSPAHRKEKAAAMPDSPAEVKT
                     QPRSTPPSMPPPPPTSSQGATRPPSFTPHTHGEDGPATSLPHGRFHGCLKWSMVCLLM
                     NGSSHSPTAIHGAPSTPNGFSNGPATSSTASLSTQHLPPACGARQLSKLKRFLTTLQQ
                     FGSDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQ
                     RELLHCARLAKQTPAQYLAQHEQLLLDASATSPVDSSELLLEVNENGKRKTPDRTKEN
                     GSDRDPLHPDHLSKRSCTLSPAQRCSPSNGLPHPTPPPPPHYRLEDMAMAHHFRDSYR
                     HPDPRELRERHRPLAIPGSRQEEVIDHRLTEREWAEEWKHLNSLLNCIMDMAEKTRRS
                     LTVLRRCQEADREELNHWIRCYSDSEEGKKGPTPISARSLNSCSGSEGSQLDVHRDFT
                     PRTLSGYMPEEIWRKAEEAVNEVKRQAMSELQKAVSDAERKAHELITTERAKMERALA
                     EAKRQASEDALTVINQQEDSSESCWNCGRKASETCSGCNAARYCGSFCQHKDWEKHHH
                     VCGQSLQGPAAAVADPLPGQPDATASPSEAGSAGPSRPCSPGPPVPLDTAVPR"
     exon            167..313
                     /gene="Cbfa2t3"
                     /inference="alignment:Splign:2.1.0"
     exon            314..391
                     /gene="Cbfa2t3"
                     /inference="alignment:Splign:2.1.0"
     exon            392..633
                     /gene="Cbfa2t3"
                     /inference="alignment:Splign:2.1.0"
     exon            634..723
                     /gene="Cbfa2t3"
                     /inference="alignment:Splign:2.1.0"
     exon            724..905
                     /gene="Cbfa2t3"
                     /inference="alignment:Splign:2.1.0"
     exon            906..1135
                     /gene="Cbfa2t3"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1221
                     /gene="Cbfa2t3"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1420
                     /gene="Cbfa2t3"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1489
                     /gene="Cbfa2t3"
                     /inference="alignment:Splign:2.1.0"
     exon            1490..1680
                     /gene="Cbfa2t3"
                     /inference="alignment:Splign:2.1.0"
     exon            1681..2684
                     /gene="Cbfa2t3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagaaaaggt acttcagggt gggctctgga ggccggccat ctcactccag ctgcaggcac
       61 ccatcagtct cctgcttcct cggaggctcc atgtcccagg catctaccac cctggagagt
      121 ggggcactcc tgccaggacc ccggggtctt cacaatggaa gtccagctca caggaaggag
      181 aaggctgcag caatgccaga ctccccggct gaagtgaaga cgcagccccg gtccacaccc
      241 cccagcatgc cgccccctcc tcccacctca tcccagggag ccacacgacc accctccttc
      301 acacctcaca cacatggcga ggatggacct gcgacgtctc taccccacgg ccgtttccac
      361 ggctgcttaa agtggtccat ggtctgtctc ttgatgaacg gcagcagcca ctcacccacg
      421 gccatccacg gtgccccgtc tacgcccaat ggcttcagca acggcccagc cacctcatcc
      481 acagcctcgc tgtccacaca gcacctgccc ccggcctgcg gggcgcggca gctcagcaaa
      541 ctcaagcggt tcctcaccac cctgcagcag tttggcagcg acatctcgcc cgagatcggg
      601 gagcgcgtgc gcacactggt gctgggactg gtgaactcaa ctctgacgat cgaagagttt
      661 cattccaagc tccaagaagc caccaacttt ccactgaggc cgttcgtcat cccctttctg
      721 aaggctaatc ttccgctgct gcagcgagag ctcctgcact gcgcccgcct ggccaagcag
      781 acgcctgccc agtacctggc ccagcacgaa cagctgctgc tggatgccag cgccacctcc
      841 ccggtggact cgtctgagct cctgctggaa gtcaacgaga acggcaagag gaaaacacct
      901 gacaggacca aagagaatgg gtcagaccgg gaccctctgc accccgacca cctcagtaag
      961 cggtcctgca ccctgagccc tgcccagcgc tgcagcccca gcaatgggct gccccaccct
     1021 acaccgcccc cgcccccgca ctatcgcctg gaggacatgg ccatggccca ccacttccgg
     1081 gactcctacc gacatcctga tccccgagag ctacgggaac gccatcggcc cctcgccata
     1141 cctgggtctc gacaagaaga agtgattgac caccggctca cggaacgtga gtgggcagaa
     1201 gagtggaagc atctcaatag tctcctgaac tgtatcatgg acatggcgga gaagacgcgg
     1261 agatccctca ccgtgctgcg ccggtgtcag gaggccgacc gcgaggaact caaccactgg
     1321 atccggtgct acagtgactc tgaggagggg aagaagggcc ccactcccat ctccgcccgg
     1381 tccctcaaca gctgcagtgg ctctgagggg tctcagctag atgttcaccg ggacttcacc
     1441 cccaggaccc tgtctggcta tatgcctgaa gagatctgga ggaaggctga agaagctgtg
     1501 aatgaggtga agcgtcaggc gatgtcggaa ctacagaaag ccgtgtctga tgcggaacgc
     1561 aaagcccacg aactcatcac cacagagcgt gccaagatgg agcgagccct ggctgaggcc
     1621 aagcgacagg cctcggagga tgccctgact gtcatcaacc agcaggagga ctccagcgag
     1681 agctgctgga actgcgggcg caaggccagt gagacttgca gtggctgtaa cgccgcacgc
     1741 tactgcgggt ccttctgtca gcacaaggac tgggagaaac accaccatgt gtgtggccag
     1801 agtctgcagg gccctgcagc tgcggtggct gacccattac ctggacagcc tgacgccact
     1861 gccagcccca gcgaagccgg ctcagcagga ccctctcgtc cctgctctcc gggcccacca
     1921 gtcccactgg acactgctgt gccccgctga cctccagatc tgccactcag cccctggacg
     1981 ccctgccctg ccaacccaac cccggcccca ccgtggtcca ccagttgcct ggagctggcc
     2041 ttgtggagtc actgctgcta ctgcttctct ccaaaataaa acacagatcc aacagaactg
     2101 cacccatgca gccccagcta cctgacaagg tccaccagga cctctacagt ctctcttcgc
     2161 aagcaccctc agaaaccacc acggagctgc agacatcggc gtcagcggaa gtgtggccag
     2221 ctgtctgccc cctctgtgtc tgtctgtgac cgtctctctt tctgcgtctg cctctcttct
     2281 gcgtgtctgg atgtcttcgt ctccttctgc ctccctgact ctcccgtgtc tccgtctctg
     2341 tgaagtccac gtgggtttct ctgtcagcag agaaacccca gttggtagct ttggttttcc
     2401 atgaagaact tttggagact ttgttttgtt ttgctggcag acaagctact tagaaacgga
     2461 cagagaagac tggggggggc ttctccccca tccctcctcg gtaagggaag aaactgtgat
     2521 tttttttttt ctagccggtg ttgctctatc tcccagccag ccccgggggg gatcggcgcg
     2581 cacacagaag agatgccgag aaacatttca gtttccaact caagaagcag tttttgtttc
     2641 aggttttatt tcttttcttt aacgtcaaac tctttggctt taag
//
