LOCUS       NM_001388507            3157 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus CACN subunit beta associated regulatory protein
            (Cbarp), transcript variant 2, mRNA.
ACCESSION   NM_001388507
VERSION     NM_001388507.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3157)
  AUTHORS   Beguin,P., Nagashima,K., Mahalakshmi,R.N., Vigot,R., Matsunaga,A.,
            Miki,T., Ng,M.Y., Ng,Y.J., Lim,C.H., Tay,H.S., Hwang,L.A.,
            Firsov,D., Tang,B.L., Inagaki,N., Mori,Y., Seino,S., Launey,T. and
            Hunziker,W.
  TITLE     BARP suppresses voltage-gated calcium channel activity and
            Ca2+-evoked exocytosis
  JOURNAL   J Cell Biol 205 (2), 233-249 (2014)
   PUBMED   24751537
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.38101.1,
                                           SRR26643429.25785.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-244               JAXUCZ010000007.1  10217353-10217596
            245-344             JAXUCZ010000007.1  10219275-10219374
            345-484             JAXUCZ010000007.1  10219495-10219634
            485-549             JAXUCZ010000007.1  10219734-10219798
            550-603             JAXUCZ010000007.1  10219927-10219980
            604-748             JAXUCZ010000007.1  10220178-10220322
            749-926             JAXUCZ010000007.1  10220976-10221153
            927-1055            JAXUCZ010000007.1  10221258-10221386
            1056-1263           JAXUCZ010000007.1  10221722-10221929
            1264-1444           JAXUCZ010000007.1  10223209-10223389
            1445-3157           JAXUCZ010000007.1  10224143-10225855
FEATURES             Location/Qualifiers
     source          1..3157
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..3157
                     /gene="Cbarp"
                     /gene_synonym="Dos"
                     /note="CACN subunit beta associated regulatory protein"
                     /db_xref="GeneID:314622"
                     /db_xref="RGD:1307185"
     exon            1..244
                     /gene="Cbarp"
                     /gene_synonym="Dos"
                     /inference="alignment:Splign:2.1.0"
     exon            245..344
                     /gene="Cbarp"
                     /gene_synonym="Dos"
                     /inference="alignment:Splign:2.1.0"
     exon            345..484
                     /gene="Cbarp"
                     /gene_synonym="Dos"
                     /inference="alignment:Splign:2.1.0"
     exon            485..549
                     /gene="Cbarp"
                     /gene_synonym="Dos"
                     /inference="alignment:Splign:2.1.0"
     exon            550..603
                     /gene="Cbarp"
                     /gene_synonym="Dos"
                     /inference="alignment:Splign:2.1.0"
     exon            604..748
                     /gene="Cbarp"
                     /gene_synonym="Dos"
                     /inference="alignment:Splign:2.1.0"
     exon            749..926
                     /gene="Cbarp"
                     /gene_synonym="Dos"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1055
                     /gene="Cbarp"
                     /gene_synonym="Dos"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1263
                     /gene="Cbarp"
                     /gene_synonym="Dos"
                     /inference="alignment:Splign:2.1.0"
     CDS             1113..2408
                     /gene="Cbarp"
                     /gene_synonym="Dos"
                     /note="protein Dos; downstream of Stk11; calcium channel,
                     voltage-dependent, beta subunit associated regulatory
                     protein; CACN beta subunit associated regulatory protein"
                     /codon_start=1
                     /product="voltage-dependent calcium channel beta
                     subunit-associated regulatory protein"
                     /protein_id="NP_001375436.1"
                     /db_xref="GeneID:314622"
                     /db_xref="RGD:1307185"
                     /translation="MGTGSSGAGTVLQFFTRLRRHASLDGASPYFKVKKWKLESSQRA
                     SSLDTRGSPKRHHFQRQRAASESMEQEGDIPHADFIQYIASAGDSVAFPPPRPFLASP
                     TSPPPTLGRLEAAEAAGGGSPETPPEHGISLGPEHAQQQDPQQEQDAEHAQCSYRDLW
                     SLRASLELHAATASDHSSSGNDRDSVRSGDSSGSGSGGGGAAPAFPPPPESPPALRPK
                     DGEARRLLQMDSGYASIEGRGAGDEVSELPAPARSPPRSPRAWPRRPRRDYSIDEKTD
                     ALFHEFLRHDPHFDDAPRHRARAHPHTHARKQWQQRGRQHSDPGGARVATPPGATRPT
                     RAPLRRGDSVDCPPEGRAPPITGDDPSIPVIEEEPGGGGSGCPGSGLCVEPAGALLDK
                     LAASLDERLFSPRLAEPVASSPVLIVAAAAPTSPDHSPA"
     exon            1264..1444
                     /gene="Cbarp"
                     /gene_synonym="Dos"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..3157
                     /gene="Cbarp"
                     /gene_synonym="Dos"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggtcaggc tgcgggaccg ggcggttacc gggtacacag agccaggggc cggagcgggc
       61 gcatcgccaa cgcgatcacg tgcgcagccc cacctctcct gcgtgcctcc tccgcgcgct
      121 gctctcccca ttcataaatt ctccgtcggc tccgcggcca ccgagctcca gagccaaccg
      181 ggagagccgt gttatctgcc gcccgccctc ccgccgccca tgggccgcac gccccggcgc
      241 tgagcctcaa aatgcagccc acggccacca tggccacagc ggccgccact actgccacgg
      301 ttgccctgac gacttcgtgg gacaatgcca ccaaccgccc cacggcggag cctgacccca
      361 tcttggacaa ctatgtgctg ctggtggtgg tgatgtcgct gttcgttgga ggcacgctgg
      421 tggtgctgtc tggcgttctt ctgctctgca aacgctgctg ggaggtgcac cagcgcttca
      481 acagggccat ggaagaaaca gaaaagacca ccactaccta cctggacaac ggcacccacc
      541 ccatacaaga ctgggcgcag ttcgagtccg actcatctct gtttccttaa cgcccaggcg
      601 tagaccccga ctgcaggggg gaagaccccg agggccagga caccgaaaca gagcgcttcc
      661 tagccaccac ctccaccggt cgccgcgtgt ccttcaacga ggctgccctg tttgaacaga
      721 gccgcaaggc tcaggacaag ggccgccggt acaccctgac agaaggggat ttccatcacc
      781 tcaagaatgc ccgcctcacc cacctccacc taccgcctct caaaatcgct accatccatg
      841 agtgtgactc gggtgaggcc agtgctgcgg ccacgcccca cccccacccg gcttccaccc
      901 ccaaggacag cttggctata ttccagcccc ctgggaagtc cctcactggc cactcggtgg
      961 gccccagctc tgccctccca ggtgatccct acagctccgt ggacttctcg gagatcagcc
     1021 cctcggcctc cagtgactct ggggagggca cctcgttaga tgcgggtacc cggggtacca
     1081 aggctgctgg gcccgagaca gcacctgggg agatgggcac aggctcctcc ggggctggca
     1141 ctgttttgca attcttcact cggctacgcc gccatgccag cctggatgga gccagcccct
     1201 acttcaaggt caagaaatgg aagttggagt ccagccagag agcgtccagt ctggacacga
     1261 gaggttcccc gaagcggcac cactttcagc gacagcgggc agccagcgag agcatggagc
     1321 aggaggggga tatcccccat gctgacttca ttcaatacat tgccagcgca ggcgactcgg
     1381 tggccttccc acccccccgc ccctttctgg ccagccccac cagcccgccc cccactctcg
     1441 gcaggctaga ggcagctgag gcggcgggag gaggaagccc cgagactcct ccggagcatg
     1501 gcatcagttt ggggcccgag catgcgcagc agcaggaccc gcagcaagag caggacgccg
     1561 agcatgcaca gtgcagctac cgtgatctgt ggagccttcg tgcttcgctc gagctccacg
     1621 cagccactgc atcagaccac agcagtagcg gcaatgaccg tgactcagtg cgcagcggcg
     1681 atagctcggg ctccggttcc gggggtggag gcgcagcacc cgccttcccg ccccctcctg
     1741 agtctccgcc tgccttgcgg cctaaggacg gcgaagcccg acgcctgtta cagatggaca
     1801 gtggctacgc gagcatcgag ggacgtggag ctggcgatga agtttctgaa cttcctgctc
     1861 cagctcggag ccctccccgc agcccgcgag cctggccacg caggccgcgc cgcgattata
     1921 gcatcgatga gaagacggac gctcttttcc atgaattcct gcgccacgat cctcattttg
     1981 atgatgctcc aagacaccgc gcacgtgcgc atcctcacac tcatgcgcgg aagcaatggc
     2041 aacagagagg ccggcagcac agcgaccccg gaggtgcacg cgtggccacg ccccctgggg
     2101 ctacccgccc cacacgtgcc cccttacgcc gtggggatag tgttgattgt cctcctgaag
     2161 gccgtgcgcc gcccatcacc ggtgatgacc catccattcc cgtcattgag gaggagcctg
     2221 gtggtggagg cagtggttgc ccaggctctg ggttatgtgt tgagcccgcc ggggcactgc
     2281 tggacaaact agcagctagc ctcgacgaga gactcttctc tccccgtctt gctgagccag
     2341 ttgcctcatc cccggtgctg attgtcgctg ctgccgcccc tacatcccct gaccacagcc
     2401 cagcctaagc tctgtgtact ggacctgcct ctcggctgct ttgccggcgg cacgtggggc
     2461 cgctgtggga atggtggcga cagcgggagc aacctgaggt tgctgtgcat gggtacgcgg
     2521 cccaaatccc aagtgtgtac aaggagtgtc ccctcgggca cttagcaggg tgcagtgggc
     2581 ctccggatgc acaaggcctc cggacccagg ctcagctgca gggaggatga agatcttgga
     2641 ttctcaagtc catatacggt tgacccccgg cacccagcct ctggccacag atgcgggtgg
     2701 agcaggttct gaggtgcgcg tgcagcctcc ctccaggatc agccgaacct ccacactcgt
     2761 gagcacgtgc tggcagtgcc actgcatgcg tgaacctact ggaggggaag tgactgcggg
     2821 gcactgagga tcagagagga acacgcgccc cagatcctta atcctttccc ctgtccatgg
     2881 tatgcacttt gtagcaactg tacctttcct ctctgagcaa taaccgactg cgcctgctcg
     2941 ctctctgcat gtgcacaggc tccagcctgt cccatccctc cccacgagct ttgggcttta
     3001 aacacagaga cagaacagcc cggtggcagc ttcaagtttc ccaagcttta tttattgcca
     3061 aaagattggg cagcctcgcc atgagtgcct gcccactccc tgccctgcgc cctgtggttg
     3121 gtcgtgttgt ctggttgatc ataaatgtct ctgcata
//
