LOCUS       NM_134449               1049 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus caveolae associated protein 3 (Cavin3), mRNA.
ACCESSION   NM_134449
VERSION     NM_134449.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1049)
  AUTHORS   Mohan,J., Moren,B., Larsson,E., Holst,M.R. and Lundmark,R.
  TITLE     Cavin3 interacts with cavin1 and caveolin1 to increase surface
            dynamics of caveolae
  JOURNAL   J Cell Sci 128 (5), 979-991 (2015)
   PUBMED   25588833
REFERENCE   2  (bases 1 to 1049)
  AUTHORS   Hernandez,V.J., Weng,J., Ly,P., Pompey,S., Dong,H., Mishra,L.,
            Schwarz,M., Anderson,R.G. and Michaely,P.
  TITLE     Cavin-3 dictates the balance between ERK and Akt signaling
  JOURNAL   Elife 2, e00905 (2013)
   PUBMED   24069528
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1049)
  AUTHORS   Ludwig,A., Howard,G., Mendoza-Topaz,C., Deerinck,T., Mackey,M.,
            Sandin,S., Ellisman,M.H. and Nichols,B.J.
  TITLE     Molecular composition and ultrastructure of the caveolar coat
            complex
  JOURNAL   PLoS Biol 11 (8), e1001640 (2013)
   PUBMED   24013648
REFERENCE   4  (bases 1 to 1049)
  AUTHORS   Schneider,K., Kocher,T., Andersin,T., Kurzchalia,T., Schibler,U.
            and Gatfield,D.
  TITLE     CAVIN-3 regulates circadian period length and PER:CRY protein
            abundance and interactions
  JOURNAL   EMBO Rep 13 (12), 1138-1144 (2012)
   PUBMED   23079727
REFERENCE   5  (bases 1 to 1049)
  AUTHORS   Hansen,C.G., Bright,N.A., Howard,G. and Nichols,B.J.
  TITLE     SDPR induces membrane curvature and functions in the formation of
            caveolae
  JOURNAL   Nat Cell Biol 11 (7), 807-814 (2009)
   PUBMED   19525939
REFERENCE   6  (bases 1 to 1049)
  AUTHORS   Izumi,Y., Hirata,M., Hasuwa,H., Iwamoto,R., Umata,T., Miyado,K.,
            Tamai,Y., Kurisaki,T., Sehara-Fujisawa,A., Ohno,S. and Mekada,E.
  TITLE     A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and
            PKCdelta are involved in TPA-induced ectodomain shedding of
            membrane-anchored heparin-binding EGF-like growth factor
  JOURNAL   EMBO J 17 (24), 7260-7272 (1998)
   PUBMED   9857183
REFERENCE   7  (bases 1 to 1049)
  AUTHORS   Izumi,Y., Hirai,Si., Tamai,Y., Fujise-Matsuoka,A., Nishimura,Y. and
            Ohno,S.
  TITLE     A protein kinase Cdelta-binding protein SRBC whose expression is
            induced by serum starvation
  JOURNAL   J Biol Chem 272 (11), 7381-7389 (1997)
   PUBMED   9054438
REFERENCE   8  (bases 1 to 1049)
  AUTHORS   Primiano,T., Gastel,J.A., Kensler,T.W. and Sutter,T.R.
  TITLE     Isolation of cDNAs representing dithiolethione-responsive genes
  JOURNAL   Carcinogenesis 17 (11), 2297-2303 (1996)
   PUBMED   8968041
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from D85435.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D85435.1, FQ220155.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1049
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..1049
                     /gene="Cavin3"
                     /gene_synonym="DIG-2; Prkcdbp; Srbc"
                     /note="caveolae associated protein 3"
                     /db_xref="GeneID:85332"
                     /db_xref="RGD:628755"
     exon            1..425
                     /gene="Cavin3"
                     /gene_synonym="DIG-2; Prkcdbp; Srbc"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..833
                     /gene="Cavin3"
                     /gene_synonym="DIG-2; Prkcdbp; Srbc"
                     /note="dithiolethione-inducible gene-2; D3T-inducible gene
                     2 protein; dithiolethione-inducible gene 2 protein; serum
                     deprivation response factor-related gene product that
                     binds to C-kinase; cavin-3; PKC-delta binding protein;
                     sdr-elated gene product that binds to c-kinase; protein
                     kinase C, delta binding protein"
                     /codon_start=1
                     /product="caveolae-associated protein 3"
                     /protein_id="NP_604444.1"
                     /db_xref="GeneID:85332"
                     /db_xref="RGD:628755"
                     /translation="MGESALEPGPVPGAPAGGPVHAVTVVTLLEKLATMLEALRERQG
                     GLAERQGGLAGSVRRIQSGLGALSRSHDTTSNTLAQLLAKAERVGSHADAAQERAVHR
                     AAQVQRLEANHGLLVARGKLHVLLFKEETEIPARAFQKAPELLGPEDQLVLGPEQPED
                     EVGESSDEEPVESRAQRLRRTGLQKVQSLKRAFSSRKGSEAAQPTPVKPPRLGPVRNS
                     EGPAEGQPAAQPAMEPVLPSALEPEPPQPTKEDPERPVLQIESAA"
     exon            426..1049
                     /gene="Cavin3"
                     /gene_synonym="DIG-2; Prkcdbp; Srbc"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1049
                     /gene="Cavin3"
                     /gene_synonym="DIG-2; Prkcdbp; Srbc"
                     /note="17 a nucleotides"
ORIGIN      
        1 gccttcggtt ttagggagag caggccgggc ggtcagagat catgggggag agcgcactgg
       61 agcccgggcc tgtgcccggg gcgccggctg ggggtccggt gcacgccgtc accgtggtga
      121 ctttgctgga gaagctggcc accatgctag aggcgctgcg ggagaggcag gggggcctgg
      181 ctgagaggca gggcggcctg gcgggctcgg tgcgccgcat ccagagtggc ctgggcgcgc
      241 tgagtcgcag ccacgacacc accagcaaca cactggcgca gctgctggcc aaggcggagc
      301 gcgtgggctc ccacgccgac gcagcccagg agcgggcagt gcaccgcgcc gctcaggtgc
      361 agcgactgga ggccaaccac gggttgctgg tggcgcgcgg gaagctgcac gtcctgctct
      421 tcaaggagga gactgaaatt ccagcccgcg ccttccagaa agcaccagag ctcttgggcc
      481 cggaggacca gttggtgcta ggcccagagc agccagagga tgaagttgga gagagttctg
      541 atgaggaacc cgtggagtcc cgggctcagc ggctgcgacg cactggctta cagaaggttc
      601 aaagcctgaa aagggctttt tccagtcgta aaggctctga agcagcacag cccacgccag
      661 tcaagccgcc acgcctaggt cctgtccgga actccgaagg cccggcagaa ggccagcctg
      721 cagctcagcc tgcaatggag cctgtgctcc cgtctgccct ggagccagaa cctcctcagc
      781 ctaccaagga agatcctgag agacctgtgc ttcaaataga gagcgcagcc tgatccctgg
      841 ggctgcctgc cccattcagc ccttatgcct tgtcccaaaa ataaatacta atcgagtgca
      901 gcacttacat ccaaataagg agagaatcct gcatccactg cccggctcca atccttcctt
      961 cctggttttc cagtctggta ccctgtgtcc tctgaaagag gaacattcgg ccttgtttag
     1021 gttcaccacc aataaaagta attttctct
//
