LOCUS       NM_001007712            2121 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus caveolae associated protein 2 (Cavin2), mRNA.
ACCESSION   NM_001007712 XM_237121
VERSION     NM_001007712.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2121)
  AUTHORS   Tang,H., Sun,L., Huang,J., Yang,Z., Li,C. and Zhou,X.
  TITLE     The mechanism and biomarker function of Cavin-2 in lung
            ischemia-reperfusion injury
  JOURNAL   Comput Biol Med 151 (Pt A), 106234 (2022)
   PUBMED   36335812
  REMARK    GeneRIF: The mechanism and biomarker function of Cavin-2 in lung
            ischemia-reperfusion injury.
REFERENCE   2  (bases 1 to 2121)
  AUTHORS   Madawala,R.J., Poon,C.E., Dowland,S.N. and Murphy,C.R.
  TITLE     PTRF is associated with caveolin 1 at the time of receptivity: but
            SDPR is absent at the same time
  JOURNAL   Histochem Cell Biol 143 (6), 637-644 (2015)
   PUBMED   25618412
  REMARK    GeneRIF: The SDPR protein was observed to be present only at the
            time of fertilisation, and also under the influence of oestrogen
            alone, where a cytoplasmic localisation in uterine epithelial cells
            was observed.
REFERENCE   3  (bases 1 to 2121)
  AUTHORS   Fork,C., Hitzel,J., Nichols,B.J., Tikkanen,R. and Brandes,R.P.
  TITLE     Flotillin-1 facilitates toll-like receptor 3 signaling in human
            endothelial cells
  JOURNAL   Basic Res Cardiol 109 (6), 439 (2014)
   PUBMED   25204797
REFERENCE   4  (bases 1 to 2121)
  AUTHORS   Hansen,C.G., Bright,N.A., Howard,G. and Nichols,B.J.
  TITLE     SDPR induces membrane curvature and functions in the formation of
            caveolae
  JOURNAL   Nat Cell Biol 11 (7), 807-814 (2009)
   PUBMED   19525939
REFERENCE   5  (bases 1 to 2121)
  AUTHORS   Ogata,T., Ueyama,T., Isodono,K., Tagawa,M., Takehara,N.,
            Kawashima,T., Harada,K., Takahashi,T., Shioi,T., Matsubara,H. and
            Oh,H.
  TITLE     MURC, a muscle-restricted coiled-coil protein that modulates the
            Rho/ROCK pathway, induces cardiac dysfunction and conduction
            disturbance
  JOURNAL   Mol Cell Biol 28 (10), 3424-3436 (2008)
   PUBMED   18332105
REFERENCE   6  (bases 1 to 2121)
  AUTHORS   Gustincich,S., Vatta,P., Goruppi,S., Wolf,M., Saccone,S., Della
            Valle,G., Baggiolini,M. and Schneider,C.
  TITLE     The human serum deprivation response gene (SDPR) maps to 2q32-q33
            and codes for a phosphatidylserine-binding protein
  JOURNAL   Genomics 57 (1), 120-129 (1999)
   PUBMED   10191091
REFERENCE   7  (bases 1 to 2121)
  AUTHORS   Mineo,C., Ying,Y.S., Chapline,C., Jaken,S. and Anderson,R.G.
  TITLE     Targeting of protein kinase Calpha to caveolae
  JOURNAL   J Cell Biol 141 (3), 601-610 (1998)
   PUBMED   9566962
REFERENCE   8  (bases 1 to 2121)
  AUTHORS   Gustincich,S. and Schneider,C.
  TITLE     Serum deprivation response gene is induced by serum starvation but
            not by contact inhibition
  JOURNAL   Cell Growth Differ 4 (9), 753-760 (1993)
   PUBMED   8241023
REFERENCE   9  (bases 1 to 2121)
  AUTHORS   Burgener,R., Wolf,M., Ganz,T. and Baggiolini,M.
  TITLE     Purification and characterization of a major
            phosphatidylserine-binding phosphoprotein from human platelets
  JOURNAL   Biochem J 269 (3), 729-734 (1990)
   PUBMED   2390065
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001007712.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081956.1, SRR26643299.39262.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676785, SAMN16676786
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-551               JAXUCZ010000009.1  57805474-57806024   c
            552-2121            JAXUCZ010000009.1  57794007-57795576   c
FEATURES             Location/Qualifiers
     source          1..2121
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q22"
     gene            1..2121
                     /gene="Cavin2"
                     /note="caveolae associated protein 2"
                     /db_xref="GeneID:316384"
                     /db_xref="RGD:1359345"
     exon            1..551
                     /gene="Cavin2"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1322
                     /gene="Cavin2"
                     /note="serum deprivation-response protein;
                     phosphatidylserine-binding protein; cavin-2; serum
                     deprivation response"
                     /codon_start=1
                     /product="caveolae-associated protein 2"
                     /protein_id="NP_001007713.1"
                     /db_xref="GeneID:316384"
                     /db_xref="RGD:1359345"
                     /translation="MGEDAAQAEKFQHPNTDMLQEKPSNPSPMPSSTPSPSLNLGSTE
                     EAIRDNSQVNAVTVHTLLDKLVNMLDAVRENQHNMEQRQINLEGSVKGIQNDLTKLSK
                     YQASTSNTVSKLLEKSRKVSAHTRAVRERLEKQCVQVKRLENNHAQLLRRNHFKVLIF
                     QEESEIPASVFVKEPVPSTAEGKELADENKSLEETLHNVDLSSDDELPGDEEALEDSA
                     EEKMEESRAEKIKRSSLKKVDSLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTP
                     NHQKASSGKSSPFKVSPLSFGRKKIREGESSAENETKLEEQVQDDHEEGSFTEGLSEA
                     SLPSGLLEGSAEDAEKSALRGNNSGVGSNADLTIEEDEEEESVALQQAQQVRYESGYM
                     LNSKEMEESSEKHVQAAVLHVDQTA"
     exon            552..2121
                     /gene="Cavin2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctccggtg cttctcgccc gagcaagaaa gttttcagcg aggaaagtaa gtttccatct
       61 gtccagccat gggagaggac gctgcacagg cagaaaagtt ccagcaccca aatacagaca
      121 tgctccagga gaagccatcc aaccccagtc caatgccttc ctccacaccg agccccagcc
      181 tgaatctggg gtccacagag gaggccatcc gagacaactc acaggtgaat gctgtcaccg
      241 tgcacactct cctggataaa ttggtcaaca tgctggacgc cgtgagggag aaccagcaca
      301 acatggagca gcggcagatc aacctggagg gctcggtgaa gggcatccag aatgacctca
      361 ccaagctctc caagtaccag gcctccacca gcaacacagt gagcaagctg ctggagaagt
      421 ctcgcaaggt cagcgctcac acgcgtgctg ttcgggagcg cctagagaag cagtgtgtac
      481 aggtgaagag gctggagaac aaccacgctc aactcctccg acgcaaccac ttcaaagtgc
      541 tcatcttcca ggaagaaagt gagatccctg ccagtgtgtt tgtgaaggag ccagttccca
      601 gcactgcaga aggcaaggag cttgctgatg agaacaagtc cttggaggaa actctgcaca
      661 atgtggacct ctcctccgat gacgaattgc ccggtgatga ggaagccctg gaagatagtg
      721 cagaagagaa gatggaggaa agcagggcag aaaagataaa aagatccagc ctcaagaaag
      781 tggatagcct caagaaagca ttttctcgcc agaatatcga gaaaaagatg aacaagctgg
      841 gaacaaagat cgtatctgtt gagaggagag aaaagattaa gaaatcgctc actcccaacc
      901 accagaaagc atcatctggg aaaagctccc ccttcaaggt ttctcccctt tccttcggtc
      961 ggaagaaaat ccgagaggga gaaagctctg cagaaaatga gaccaaactg gaagagcagg
     1021 tgcaggacga ccatgaggag ggctcgttca cagaaggtct ttctgaagca tccctcccca
     1081 gcggcctgtt ggagggcagc gcagaagatg ctgagaagtc agcattgaga gggaacaact
     1141 caggcgtggg cagcaatgcc gatctgacca ttgaagaaga tgaagaagag gagtcggtgg
     1201 ccctgcagca ggcccagcag gtgcgctatg agagtggcta catgctcaac tccaaggaga
     1261 tggaggaatc cagtgagaaa cacgtccagg cggctgtgct gcatgtggat cagactgcct
     1321 gagtgcacag cccgaagact gggcaagctg cactcagcag ctcgctcagg tgcatccaca
     1381 tcgtggaagc cacctctgga acccttcatc tctacctgct cccgactggg accgtccagg
     1441 ccttaatcac taaccataca gtagcctcgg acatacatgg gatcacagaa gcaaactgcc
     1501 agggattcca tttctaattt gctcgtaggt tctatttctg tagaatttct ccaagatttt
     1561 aagaagaaag aaatggagca gtttttaaaa aaaatcgact atctctttgg cttagtcaga
     1621 aaaactagag gctatttaag gtagtagtta taaaaagtga tttttttttt ttttgctcgt
     1681 tctatcagct tgctgaatag tgtggcagta atgtagtgaa ttcctactgt attctgtgaa
     1741 tgattattct tcaagtatgt ggtatggaac atacataagt ctgtaggctg agaatataac
     1801 tattttaaga agaaaacatt tacaaaagat agagcagaag ggtcagttgg ttattctctt
     1861 acagaaacca ttgtttattg gaagggggct gaaagactgt gctgacgggg agctaatagc
     1921 actgggactg ctgaggtaga aaactaagat ggaaagattg gaaagtgaga gaaatggagg
     1981 acgaagaatg gcaaaaagtg acgacaaaga ggaaaaaaga cgtgcttaaa aagtgaaata
     2041 ctggggctgg agatttagct cagtggttgc ctaggaagcg caaggctctg ggttcagtcc
     2101 ccagctccga aaaaaagaac c
//
