LOCUS       NM_001025128            1546 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cytosolic arginine sensor for mTORC1 subunit 1
            (Castor1), mRNA.
ACCESSION   NM_001025128
VERSION     NM_001025128.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1546)
  AUTHORS   Hallett,J.E.H. and Manning,B.D.
  TITLE     CASTORing New Light on Amino Acid Sensing
  JOURNAL   Cell 165 (1), 15-17 (2016)
   PUBMED   27015302
REFERENCE   2  (bases 1 to 1546)
  AUTHORS   Chantranupong,L., Scaria,S.M., Saxton,R.A., Gygi,M.P., Shen,K.,
            Wyant,G.A., Wang,T., Harper,J.W., Gygi,S.P. and Sabatini,D.M.
  TITLE     The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway
  JOURNAL   Cell 165 (1), 153-164 (2016)
   PUBMED   26972053
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC091274.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091274.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1546
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..1546
                     /gene="Castor1"
                     /gene_synonym="Gatsl3; RGD1304774"
                     /note="cytosolic arginine sensor for mTORC1 subunit 1"
                     /db_xref="GeneID:360969"
                     /db_xref="RGD:1304774"
     exon            1..171
                     /gene="Castor1"
                     /gene_synonym="Gatsl3; RGD1304774"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..1054
                     /gene="Castor1"
                     /gene_synonym="Gatsl3; RGD1304774"
                     /note="GATS-like protein 3; Gats protein; GATS
                     protein-like 3"
                     /codon_start=1
                     /product="cytosolic arginine sensor for mTORC1 subunit 1"
                     /protein_id="NP_001020299.1"
                     /db_xref="GeneID:360969"
                     /db_xref="RGD:1304774"
                     /translation="MELHILEHRVRVLSLARPGLWLYTHPLIKLLFLPSRSRCKFFSL
                     TETPEDYTLMVDEEGFKELPPSEFLQVAEATWLVMNVSHSGSVVQAAGVTKIARSVIA
                     PLAEHHVSVLMLSTYQTDFILVREQDLSVVIHTLAREFQIYREVGGEPVPVTGDDSSN
                     GFPQAQHGPSPTVHPIQSPQNRFCVLTLDPETLPAVATTLIDVLFYSHSVPKEAASGG
                     PESTSIPFFAFSLIEGYISIVMDAETQKKFPSDLLLTSSSGELWRMVRIGGQPLGFDE
                     CGIVAQIAGPLAAVDVSAYYISTFNFDHALVPEDEISCVIDILQRRQEGLASKDP"
     exon            172..242
                     /gene="Castor1"
                     /gene_synonym="Gatsl3; RGD1304774"
                     /inference="alignment:Splign:2.1.0"
     exon            243..427
                     /gene="Castor1"
                     /gene_synonym="Gatsl3; RGD1304774"
                     /inference="alignment:Splign:2.1.0"
     exon            428..560
                     /gene="Castor1"
                     /gene_synonym="Gatsl3; RGD1304774"
                     /inference="alignment:Splign:2.1.0"
     exon            561..684
                     /gene="Castor1"
                     /gene_synonym="Gatsl3; RGD1304774"
                     /inference="alignment:Splign:2.1.0"
     exon            685..798
                     /gene="Castor1"
                     /gene_synonym="Gatsl3; RGD1304774"
                     /inference="alignment:Splign:2.1.0"
     exon            799..881
                     /gene="Castor1"
                     /gene_synonym="Gatsl3; RGD1304774"
                     /inference="alignment:Splign:2.1.0"
     exon            882..976
                     /gene="Castor1"
                     /gene_synonym="Gatsl3; RGD1304774"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1515
                     /gene="Castor1"
                     /gene_synonym="Gatsl3; RGD1304774"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgcatcgcc tcctgcctag gtctagctgg cggcgaggcc agggctgcgg gatctgcgat
       61 ggaacttcac atcctagagc accgggtgcg agtactgagc ctcgcgcgtc cgggcctctg
      121 gctctacacc cacccgctca tcaagctgct cttcctgccc agtcgcagcc ggtgcaagtt
      181 cttcagcctg actgagactc cggaagatta cacactcatg gtggatgaag agggctttaa
      241 agagctaccc ccatccgagt tcctgcaagt ggcggaggcc acgtggctgg tgatgaacgt
      301 gtctcacagt ggctcggtgg tgcaggctgc tggagttacc aagattgccc ggtctgtcat
      361 tgccccgctg gctgaacacc acgtgtctgt tctgatgttg tccacgtacc agacagactt
      421 catcctggta cgggagcagg acctgtctgt ggtgatccac acgctggccc gagagtttca
      481 aatctaccgt gaagtaggcg gggagcctgt gcctgtcacg ggggacgatt ccagcaatgg
      541 ctttccccaa gcccagcacg ggcccagtcc cacggtgcat cccattcaga gcccacagaa
      601 ccgcttttgt gtcctgacac tggaccctga gacgttgccg gctgttgcca ccaccctcat
      661 cgatgtcctc ttctactcgc acagtgtccc caaggaggca gcctcgggtg gtcctgagtc
      721 aacttccatt ccattcttcg ccttctccct cattgagggt tacatctcca ttgtcatgga
      781 cgcagagacc cagaaaaagt tccccagtga cctcctgctg accagttctt ccggggagct
      841 gtggaggatg gtgcgcatcg ggggacagcc cctgggcttc gatgagtgtg ggattgtggc
      901 ccagatcgcg ggccccctgg cggctgtcga tgtctccgct tactacatca gcactttcaa
      961 ctttgaccat gcgctggttc ctgaagacga gatcagctgt gtcattgata tactccagcg
     1021 aaggcaggaa ggcctggctt ccaaagatcc atagggaaca gcagacccaa caccgtctta
     1081 cccccctggg ctttcagaga cttttctgag ctatttcctg aagcttcaga gtgagcccct
     1141 gattctgcca agggatcccg gttctgccgt ttgtacgtaa gccatatgga gctggaactt
     1201 gtggttgtgg acatgtctgc ccacagaaga caccttggtg cttggggctt agaccctcga
     1261 cccaacactt tctatgtgac ctcagcattg cggtgcctgg ctgcgtgcct gcctacagct
     1321 cgggctgcct ctcacctggc taaggctcat gtcccccagg gctgggctct gatctccagc
     1381 ctgggaccca gccagatgag ttcccacagt gcactccctt cttggggctc tgaaagaaga
     1441 attacatctc acttttattt tcgtgactgt ttaaataaat aaaagacttg gcggggctgt
     1501 gccctctggt tccgaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//
