LOCUS       NM_001402046            3875 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus CAS1 domain containing 1 (Casd1), mRNA.
ACCESSION   NM_001402046 XM_039108597
VERSION     NM_001402046.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3875)
  AUTHORS   Baumann,A.M., Bakkers,M.J., Buettner,F.F., Hartmann,M., Grove,M.,
            Langereis,M.A., de Groot,R.J. and Muhlenhoff,M.
  TITLE     9-O-Acetylation of sialic acids is catalysed by CASD1 via a
            covalent acetyl-enzyme intermediate
  JOURNAL   Nat Commun 6, 7673 (2015)
   PUBMED   26169044
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Mar 3, 2022 this sequence version replaced XM_039108597.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643288.17822.1,
                                           SRR26643297.15253.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-391               JAXUCZ010000004.1  33613805-33614195
            392-488             JAXUCZ010000004.1  33620787-33620883
            489-609             JAXUCZ010000004.1  33621433-33621553
            610-654             JAXUCZ010000004.1  33669827-33669871
            655-717             JAXUCZ010000004.1  33671339-33671401
            718-762             JAXUCZ010000004.1  33674554-33674598
            763-886             JAXUCZ010000004.1  33675027-33675150
            887-1101            JAXUCZ010000004.1  33676288-33676502
            1102-1524           JAXUCZ010000004.1  33679260-33679682
            1525-1614           JAXUCZ010000004.1  33680598-33680687
            1615-1734           JAXUCZ010000004.1  33691863-33691982
            1735-1891           JAXUCZ010000004.1  33692793-33692949
            1892-1971           JAXUCZ010000004.1  33694211-33694290
            1972-2073           JAXUCZ010000004.1  33696447-33696548
            2074-2214           JAXUCZ010000004.1  33698183-33698323
            2215-2292           JAXUCZ010000004.1  33699170-33699247
            2293-2385           JAXUCZ010000004.1  33703477-33703569
            2386-3875           JAXUCZ010000004.1  33704332-33705821
FEATURES             Location/Qualifiers
     source          1..3875
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q21"
     gene            1..3875
                     /gene="Casd1"
                     /note="CAS1 domain containing 1"
                     /db_xref="GeneID:678772"
                     /db_xref="RGD:1596912"
     exon            1..391
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             259..2652
                     /gene="Casd1"
                     /EC_number="2.3.1.45"
                     /note="CAS1 domain-containing protein 1"
                     /codon_start=1
                     /product="N-acetylneuraminate 9-O-acetyltransferase"
                     /protein_id="NP_001388975.1"
                     /db_xref="GeneID:678772"
                     /db_xref="RGD:1596912"
                     /translation="MAALAYNLGKREINHYFSVRSAKVLALVAVLLLAACHLASRHYR
                     GNDSCEFLLSSGRFLGEKVWQPHSCMMHKYKISEAKTCLVDKHIAFIGDSRIRQLFYS
                     FVKIINPQFKEEGNKHENIPFEDKVASLKVDFLWHPEVNGSMKQCIKLWTEDVVSKPH
                     VIVAGAATWSIKIHNGSEEALSQYKMNITSIAPLLEKLAKTSDVYWVLQDPVYEDLLS
                     ENRKMITNEKIDAYNEAAVSILNSSTRTSKSNVKMFSVSKLIAQETIMESLDGLHLPE
                     SSRETSAMILMNVYCNKILKPVDGSCCQPRPPLTLIQKLAACFFTLSIIGYLIFYVIH
                     RNAHRKNKPCPDLESGEEKKNIINTPVSSLEILLQSFCKLGLIMAYFYMCDRANLFMK
                     ENKFYTHSSFFIPIIYILVLGVFYNENTKETKVLNREQTDEWKGWMQLVILIYHISGA
                     STFLPVYMHIRVLVAAYLFQTGYGHFSYFWIKGDFGIHRVCQVLFRLNFLVVVLCIVM
                     DRPYQFYYFVPLVTVWFMVIYITLALWPQVTQKKANGNGFWYLGLLLKLAFLLLCICF
                     LAYSQGAFEKIFSLWPLSKCFELEGSVYEWWFRWRLDRYVVLHGALFAFIYLALQRRQ
                     ILSEGKGEPLFSNKISNFLLFVSVVSFLTYSIWASSCKNKAECNELHPSVSVVQIVAF
                     ILIRNTPGYARSIYSSFFAWFGKISLELFICQYHIWLAADTRGILVLIPGNPTLNIAV
                     STFIFVCVAHEISQITADLAHVVIPKDNPALFRRLACTLAFFAGLLVLSSIQDKSRL"
     exon            392..488
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            489..609
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            610..654
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            655..717
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            718..762
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            763..886
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            887..1101
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..1524
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1525..1614
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1615..1734
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1735..1891
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1892..1971
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1972..2073
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2074..2214
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2215..2292
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2293..2385
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2386..3875
                     /gene="Casd1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagacaggcg gccagggcgc ctggggcacc ggcacggcgg agcaacggcg gcggggtttg
       61 ggggaggccg acgtgggcac ggggaaggcc ggcggcaccg aggccgcagg ctctggctcc
      121 tcggccgacg gtgcgggcga cgggcaaggg agctggcggc tgctcctcgg ctggctactg
      181 cgccggccgc cccagtgctg cccctgcgcg gcgccccttc cccgctccgc cgcgcactgt
      241 tgtcatggag gaaccaagat ggcggctctg gcctacaacc tgggcaagcg ggagatcaac
      301 cactacttca gcgtgaggag cgccaaggtg ctggcgctgg tggccgtgct gctgctcgcc
      361 gcgtgccacc tcgcgtcccg ccactaccga ggcaatgatt cgtgtgaatt ccttctctca
      421 agtggcagat ttcttggaga aaaagtttgg caacctcaca gttgtatgat gcataaatac
      481 aaaataagtg aagcaaagac ttgccttgta gataaacaca ttgcatttat tggagattcc
      541 aggatacgtc aattatttta ttcttttgta aaaatcatta acccccagtt taaagaagaa
      601 ggaaataagc atgaaaacat tccttttgaa gacaaagttg catcccttaa agtggatttt
      661 ctttggcatc cagaagttaa tggttctatg aaacagtgta tcaagttgtg gactgaggac
      721 gtggtttcga agccccatgt gattgtagcg ggagcagcca cgtggtccat caagattcat
      781 aatggtagcg aggaagcact gtctcaatat aaaatgaata tcacctccat agcaccgctc
      841 ttagaaaaac tggccaagac tagtgatgtt tattgggtct tacaagaccc agtttatgaa
      901 gatctcttaa gtgaaaatag aaaaatgatt actaacgaga agatagacgc ctacaacgaa
      961 gctgcagtca gcattctgaa cagcagcacc aggacatcca agtccaatgt caagatgttc
     1021 agtgtttcca aactcatcgc ccaagaaacc atcatggagt ctttggatgg cttacacctt
     1081 cctgaatcaa gcagagaaac tagtgcaatg attctcatga acgtgtactg taataaaatt
     1141 ttgaagcccg tggatggttc ctgctgtcag cctcggccac ctcttactct cattcagaag
     1201 ctagctgctt gcttttttac tttatccatt attgggtatt taatcttcta tgtaattcat
     1261 cgtaatgctc accggaagaa taaaccatgt cctgatttgg aaagtggtga ggaaaagaag
     1321 aatatcatca atactcctgt gtcctcatta gaaatacttt tacagtcttt ttgcaaactt
     1381 ggcctgatta tggcttattt ctatatgtgt gaccgtgcaa acctgtttat gaaggaaaac
     1441 aaattttata cacattcatc attctttatt ccaattattt acatcttggt tttgggagtg
     1501 ttttacaatg aaaacacaaa agagacgaaa gtgttaaata gagagcagac ggatgaatgg
     1561 aagggctgga tgcagctggt gattctcatc tatcacatct caggggccag cacgtttctg
     1621 cctgtgtaca tgcacattcg cgttctggtg gctgcttatc tgtttcagac agggtatggg
     1681 catttctctt acttttggat caaaggagat ttcggaattc atagagtatg tcaggtctta
     1741 tttcgtctca atttcctggt tgtggtgtta tgtatcgtaa tggatcgacc atatcaattc
     1801 tattactttg tccccttggt caccgtgtgg ttcatggtca tatatatcac tttagcactg
     1861 tggccacaag taacccagaa aaaggcgaat ggaaatggtt tctggtatct cggcttactg
     1921 ttgaaactag cctttctgct gctgtgcata tgtttcttgg catattctca gggtgcgttt
     1981 gagaagatct tttctctttg gccactttcc aaatgttttg aactggaagg gagtgtgtat
     2041 gaatggtggt tcagatggag gttagaccgt tacgtcgtcc tccatggggc tctgtttgcc
     2101 ttcatttatc tggctttgca gagacggcag atactttctg aaggaaaggg tgaacctctt
     2161 ttttcaaaca aaatctccaa ctttctattg tttgtttcag tagtgtcttt cttgacctat
     2221 tccatctggg ctagcagttg caaaaacaaa gcagagtgca acgaactcca cccttctgtg
     2281 tctgtggtcc agatcgtagc cttcatcctg ataaggaaca cccctggata tgcccgctct
     2341 atttacagtt cattttttgc ttggttcgga aaaatttcac tagagctgtt catctgtcag
     2401 taccacatat ggctggcggc ggacacacgg ggcatcctgg tactcatccc cgggaacccg
     2461 acgctcaaca tcgccgtcag cactttcatc ttcgtgtgcg tggcgcatga gatctcgcag
     2521 atcactgctg acctcgcgca cgtggttatt cctaaagata acccggccct cttcagaagg
     2581 ctggcgtgta cacttgcatt ctttgccgga ctacttgtct tatcctccat tcaagataaa
     2641 tcaagactgt aggctcctga aatcctaaca gcaaacccct cgggcttact ttgcatctgc
     2701 ctagacaaga aaatcatctg tgtgaagata ttaatgactg tgtaaatata aacatttggc
     2761 aacgggacag tcttgtgatg tccgttgaac ttgtgtgatt gtatatatca acactgtgta
     2821 tatccaatgt gaaatgcata caaacaatga accaagctgc atcgtataga agtgcatgtg
     2881 gaaaacactt ttctaccaga ttagtgtctc catttatagt gattctagtt agcatatgaa
     2941 ggcagggaat gatggactta ccagtaaacc tagtaagtaa gttaattagc ttagtgacac
     3001 cactgtgtgt cttgatatcc tctgtgtgct aatcattgtg tctgcatccg tacacacaga
     3061 acctactcct tcacagacaa tttagtaccg aagtgacttg cagtgttctt ttctgtcaca
     3121 tgtgcaatgc tgtggaatga ggaaccgtat gtctttaacc catatgtatt tatatccgct
     3181 gtgtgtttcc tgatgtgatt tttttcctag ctgtggttcg caggtgtgta agcctaattc
     3241 tttgtacact ttgcccttca gagttgttct aaagctctgt gacaaggttt tgttattgtg
     3301 aatgttgttg ttgcttattt tcaaaaaggc caaattttcc tttcaatcca aacagtctat
     3361 ttctttttcc taatctatac caggatttaa aaaaacaaaa acaaacataa caaacaaaaa
     3421 actaccctgt gggtccatta atgtttgctg gccactgatt aagtagtgta tattatttcc
     3481 aatgtttgga agtttcttta tagccatttg gtattcccta ttatgtcctc attttttaaa
     3541 aaaatattta tcgatctgaa cctgtacagc atagtgaagt tccaaatcct ttgattgaag
     3601 tgtatgacca tagtagaatt tcgagtaaac tgctgatttt taacaataaa tgatctgttc
     3661 agttttttta taagctaact gttagaggtt tacatttatt tatctgttgt acagatctga
     3721 ttatgatttt taatgtataa aatattgcac ttatttgctt ttattctgtg tgtggtaaga
     3781 tatatgttct gttcatagta tgtgacaata agaagtaatt taaacaataa ataaacattc
     3841 agtggatgct tatttttgta ttggcaaagt atcaa
//
