LOCUS       NM_001106319            2970 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus cysteinyl-tRNA synthetase 1 (Cars1), mRNA.
ACCESSION   NM_001106319 XM_001065753 XM_215134
VERSION     NM_001106319.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2970)
  AUTHORS   Liu,C., Gamper,H., Shtivelband,S., Hauenstein,S., Perona,J.J. and
            Hou,Y.M.
  TITLE     Kinetic quality control of anticodon recognition by a eukaryotic
            aminoacyl-tRNA synthetase
  JOURNAL   J Mol Biol 367 (4), 1063-1078 (2007)
   PUBMED   17303165
REFERENCE   2  (bases 1 to 2970)
  AUTHORS   Davidson,E., Caffarella,J., Vitseva,O., Hou,Y.M. and King,M.P.
  TITLE     Isolation of two cDNAs encoding functional human cytoplasmic
            cysteinyl-tRNA synthetase
  JOURNAL   Biol Chem 382 (3), 399-406 (2001)
   PUBMED   11347887
REFERENCE   3  (bases 1 to 2970)
  AUTHORS   Kim,J.E., Kim,K.H., Lee,S.W., Seol,W., Shiba,K. and Kim,S.
  TITLE     An elongation factor-associating domain is inserted into human
            cysteinyl-tRNA synthetase by alternative splicing
  JOURNAL   Nucleic Acids Res 28 (15), 2866-2872 (2000)
   PUBMED   10908348
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_215134.4, XM_001065753.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2970
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q42"
     gene            1..2970
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /note="cysteinyl-tRNA synthetase 1"
                     /db_xref="GeneID:293638"
                     /db_xref="RGD:1310747"
     exon            1..99
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..2321
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /EC_number="6.1.1.16"
                     /note="cysteinyl-tRNA synthetase, cytoplasmic"
                     /codon_start=1
                     /product="cysteine--tRNA ligase, cytoplasmic"
                     /protein_id="NP_001099789.1"
                     /db_xref="GeneID:293638"
                     /db_xref="RGD:1310747"
                     /translation="MAGSSAEQGKGRRVQPQWSPPAGTEPCRLRLYNSLTRNKDVFIP
                     QDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLRDYFQYDVFYCMNITDIDDKI
                     IRRARQNYLFEQYREQKPSAAQLLKDVGDAMKPFSVKLSETTDPDKRQMLERIQNSVK
                     LATEPLEQAVHSNPSGEEVDSRVQVLLEEAKDLLSDWLDSTGGSEVTDNSIFSKLPKF
                     WEEEFHKDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYASNGSVYFDTAKFA
                     ASEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWP
                     CPWGKGRPGWHIECSAMAGSLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVR
                     YFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTME
                     SALQYEKFMNEFFLNVKDILRAPVDITGQFEKWEAEEVELNKNFYDKKTAVHEALCDN
                     IDTRTVMEEMRALVSQCNLYMAARKAARRRPNRALLENIAMYLTHMLKIFGAIEEENP
                     LGFPVGGPGTNLNLESTVMPYLQVLSEFREGVRKIAREKKVLEVLQLSDALRDDILPE
                     LGVRFEDHEGLPTVVKLVDRDTLLKEKEEKKRAEEEKRRKKEEAARKKQEQEAAKLAK
                     MKTPPSEMFRSETDKYSKFDENGLPTHDTEGKELSKGQTKKLKKLFEAQEKVYKEYLQ
                     QLQNSSLQ"
     exon            100..191
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            192..280
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            281..377
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            378..476
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            477..626
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            627..767
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            768..856
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            857..978
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            979..1091
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1220
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1350
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..1454
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            1455..1552
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            1553..1742
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            1743..1811
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            1812..1893
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            1894..1974
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            1975..2042
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            2043..2102
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            2103..2186
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
     exon            2187..2970
                     /gene="Cars1"
                     /gene_synonym="Cars"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacttccggc gccgcggttg catcagattc tggaaagcgt ctgtggcggc agacgcgggt
       61 cttgattccc agtgatggca ggttcctccg cggagcaggg taaaggccgg cgagtgcagc
      121 ctcagtggtc ccctccagca gggactgagc cctgccggct ccgcctatac aatagcctca
      181 cccggaacaa ggatgtattt atacctcaag atgggaagaa ggtgacgtgg tactgttgcg
      241 ggccgactgt ctatgatgcg tctcacatgg gacatgccag gtcctacatc tctttcgata
      301 tcctgcggag ggtgctgagg gattacttcc agtatgatgt cttttactgc atgaacatca
      361 cagacattga tgataagatc atcaggaggg cgcggcagaa ctacctgttt gagcagtatc
      421 gggagcagaa accttcggct gcccagcttc tgaaggatgt tggtgatgcc atgaagccat
      481 tctcagtcaa gttaagtgag acaacagacc ctgacaagag gcagatgctg gagaggatcc
      541 agaactctgt gaagcttgcc acagaaccac tggaacaggc tgtgcattcc aacccctctg
      601 gagaggaagt agacagccgt gtacaggtgt tgctggagga agcaaaggac ttgctctctg
      661 actggctgga ttctacaggt ggcagtgagg tgactgacaa ctctattttc tccaaactgc
      721 ccaagttctg ggaagaagag ttccacaaag acatggaagc cctgaatgtt ctccctcctg
      781 atgtcctgac ccgtgtcagt gaatatgtgc cggaaattgt gaacttcgtc cagaagattg
      841 tggacaacgg ttatggctat gcttcaaatg ggtctgtcta cttcgacaca gccaagttcg
      901 ctgctagtga aaagcactcc tatggcaagc tggtgcctga ggctgttggg gatcagaaag
      961 cacttcagga aggggaaggt gatctgagca tctctgctga ccgccttagt gagaaacgct
     1021 ctcccaatga cttcgccttg tggaaggcct ccaagccagg agagccatcc tggccttgcc
     1081 cctggggaaa gggtcgtcca ggatggcaca tagagtgctc cgctatggca ggctcgctcc
     1141 tgggagcctc aatggacatt catggtggag gctttgacct ccgcttcccc caccatgaca
     1201 atgagctggc acagtcagag gcctactttg agaatgactg ctgggtcagg tacttcttgc
     1261 acacgggcca cttgacaata gcaggctgca agatgtccaa gtcactgaaa aacttcatca
     1321 ccatcaaaga tgccttgaag aagcactcag cacggcagct gcggctggct ttcctcatgc
     1381 actcctggaa agacacactg gactattcca gcaacactat ggagtctgca cttcagtatg
     1441 aaaagttcat gaatgaattt ttcttaaacg tgaaagacat cctccgagcc cctgtggaca
     1501 tcactggcca gtttgaaaag tgggaagccg aagaagtgga gctcaataag aacttctatg
     1561 acaagaagac cgcagttcat gaagccctgt gtgataacat tgacacccgt actgtcatgg
     1621 aggagatgcg ggctttggtc agtcagtgca acctctacat ggcagccagg aaggccgcaa
     1681 ggaggaggcc caacagggct ctgctggaaa acattgccat gtacctcacc cacatgctga
     1741 agatctttgg agccatagag gaggagaacc ccctgggttt cccggttggt gggcctggaa
     1801 ccaacctgaa tctcgagtct acagtcatgc cctacctgca ggtattatcg gaattcaggg
     1861 agggtgtgcg aaagattgcc cgagagaaaa aagtccttga ggttctgcag ctcagtgatg
     1921 ccctccggga tgacatcctg cctgagcttg gggtgcggtt tgaagaccac gaaggactgc
     1981 caacagtggt gaagttggtg gacagagaca ccttactgaa agagaaggaa gaaaagaaaa
     2041 gggctgaaga agagaagagg aggaagaaag aggaggcggc caggaagaaa caggagcaag
     2101 aagcagcaaa gctggccaag atgaagacgc cacccagtga gatgttccgc tcagaaaccg
     2161 acaagtattc taagtttgat gaaaatggtc tgcctaccca cgacactgaa ggcaaagagc
     2221 tgagcaaggg ccagaccaag aagttgaaga agctctttga agctcaggag aaagtgtaca
     2281 aggagtatct gcaacagttg cagaatagca gcctccagtg ataccaccgc agcccagaag
     2341 gggtccctgc cagcctggcc gacatggact aggccacacg gctcaggccc gccctcatca
     2401 tgtttacagc tgctctcaca cctgaatcag gcagagtggt agcagctctg ggacactggt
     2461 aataaattct tctgaaccac cggcaaggcc cggtctgccc tctcagcact ggggcgagct
     2521 ggcctacagg tgcctgctca gcagcttggg acttaggcct cctggtcagt tgagcccctt
     2581 cagccagcct gccggaggaa tttccctcac atcggcgggc cgagctaatc tctgctgtgt
     2641 tggcacgttt ggtggtattg gagtaggaaa aaggccgact cagcccaacg gatccccctg
     2701 agccccagac aaaagccact cagttgtctg tctggctctg atgaacacac actgcaggtt
     2761 tcccagagca actgacaaag tggcagcagg acagttgccc tgtgggatgg ggctctggca
     2821 agctgcctgc gactgccgtt atgacagcaa gcccagatca gcaccacggc ttgtaagata
     2881 agggattctc tagtccaacc tgaagtgttt ctcctctcca cctgctcctg cctgtttgtt
     2941 cgcccttgcc aagaatcagc acctatgctg
//
