LOCUS       NM_001014138            4452 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus capping protein regulator and myosin 1 linker 3
            (Carmil3), mRNA.
ACCESSION   NM_001014138 XM_341318
VERSION     NM_001014138.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4452)
  AUTHORS   Lanier,M.H., McConnell,P. and Cooper,J.A.
  TITLE     Cell Migration and Invadopodia Formation Require a Membrane-binding
            Domain of CARMIL2
  JOURNAL   J Biol Chem 291 (3), 1076-1091 (2016)
   PUBMED   26578515
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000015.1.
            
            [WARNING] On Jul 19, 2024 this sequence was replaced by
            NM_001014138.3.
            
            On Aug 28, 2012 this sequence version replaced NM_001014138.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760393 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                JAXUCZ010000015.1  32948975-32949022
            49-143              JAXUCZ010000015.1  32950625-32950719
            144-194             JAXUCZ010000015.1  32950990-32951040
            195-254             JAXUCZ010000015.1  32951161-32951220
            255-370             JAXUCZ010000015.1  32951304-32951419
            371-468             JAXUCZ010000015.1  32951604-32951701
            469-539             JAXUCZ010000015.1  32951952-32952022
            540-613             JAXUCZ010000015.1  32952125-32952198
            614-689             JAXUCZ010000015.1  32952418-32952493
            690-778             JAXUCZ010000015.1  32952575-32952663
            779-873             JAXUCZ010000015.1  32953185-32953279
            874-960             JAXUCZ010000015.1  32953504-32953590
            961-1070            JAXUCZ010000015.1  32953749-32953858
            1071-1148           JAXUCZ010000015.1  32953995-32954072
            1149-1225           JAXUCZ010000015.1  32954508-32954584
            1226-1330           JAXUCZ010000015.1  32954665-32954769
            1331-1400           JAXUCZ010000015.1  32954861-32954930
            1401-1482           JAXUCZ010000015.1  32955432-32955513
            1483-1579           JAXUCZ010000015.1  32955614-32955710
            1580-1634           JAXUCZ010000015.1  32955856-32955910
            1635-1807           JAXUCZ010000015.1  32955987-32956159
            1808-1876           JAXUCZ010000015.1  32956373-32956441
            1877-1970           JAXUCZ010000015.1  32956636-32956729
            1971-2069           JAXUCZ010000015.1  32956824-32956922
            2070-2198           JAXUCZ010000015.1  32957220-32957348
            2199-2312           JAXUCZ010000015.1  32957511-32957624
            2313-2488           JAXUCZ010000015.1  32958066-32958241
            2489-2576           JAXUCZ010000015.1  32958972-32959059
            2577-2711           JAXUCZ010000015.1  32959181-32959315
            2712-2775           JAXUCZ010000015.1  32959544-32959607
            2776-2984           JAXUCZ010000015.1  32959939-32960147
            2985-3085           JAXUCZ010000015.1  32960649-32960749
            3086-3401           JAXUCZ010000015.1  32961720-32962035
            3402-3530           JAXUCZ010000015.1  32962351-32962479
            3531-3597           JAXUCZ010000015.1  32962917-32962983
            3598-3687           JAXUCZ010000015.1  32963081-32963170
            3688-3806           JAXUCZ010000015.1  32964657-32964775
            3807-3987           JAXUCZ010000015.1  32964910-32965090
            3988-4107           JAXUCZ010000015.1  32965250-32965369
            4108-4452           JAXUCZ010000015.1  32965485-32965829
FEATURES             Location/Qualifiers
     source          1..4452
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p13"
     gene            1..4452
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /note="capping protein regulator and myosin 1 linker 3"
                     /db_xref="GeneID:361041"
                     /db_xref="RGD:1359120"
     exon            1..48
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     CDS             9..4133
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /note="leucine-rich repeat-containing protein 16B; leucine
                     rich repeat containing 16B; capping protein regulator and
                     myosin 1 linker protein 3"
                     /codon_start=1
                     /product="capping protein, Arp2/3 and myosin-I linker
                     protein 3"
                     /protein_id="NP_001014160.2"
                     /db_xref="GeneID:361041"
                     /db_xref="RGD:1359120"
                     /translation="MAKASVELTRELQDSIRRCLSQGAVLQQHRVKLETKPKKFEDRV
                     LALTSWRLHLFPLKVPAKVESSFNVLEIRAFNTLSQNQILVETERGVVSMRLPSAESV
                     DQVTRHVSSALSKVCPGPGCLIRRGNADTPEGPRDTSPNSETSTSTTHSVCGGFSETY
                     AALCDYNGLHCREEVQWDVDTIYHAEDNREFNLLDFSHLESRDLALMVAALAYNQWFT
                     KLYCKDLRLGSEVLEQVLHTLSKSGSLEELVLDNAGLKTDFVQKLAGVFGENGSCVLH
                     ALTLSHNPIEDKGFLSLSQQLLCFPAGLTKLCLAKTAVSPRGLQALGQTFGANPAFAS
                     SLRYLDLSKNPGLLATDEANALYSFLAQPNALVHLDLSGTDCAVDLLLGALLHGCCSH
                     LTYLNLARNSCSHRKGREAPPAFKQFFSSAYTLSHVNLSATRLPLEALRALLQGLSLN
                     SHLSDLHLDLSSCELRSAGAQALQEQLGAVTCIGSLDLSDNGFDSDLLTLVPALGKNK
                     SLKHLFLGKNFNVKAKTLEEILHKLVQLIQEEDCSLQSLSVADSRLKLRTSILINALG
                     SNTCLAKVDLSGNGMEDIGAKMLSKALQINSSLRTILWDRNNTSALGFLDIARALESN
                     HTLRFMSFPVSDISQAYRSAPERTEDVWQKIQWCLVRNNHSQTCPQEQAFRLQQGLVT
                     SSAEQMLQRLCGRVQEEVRALRLCPLEPVQDELLYARDLIKDAKNSRALFPSLCELGH
                     VLANDGPVRQRLESVASEVSKAVDKELQVILESMVSLTQELCPVAMRVAEGHNKMLSN
                     VAERVTVPRNFIRGALLEQAGQDIQNKLDEVKLSVVTYLTNSIVDEILQELYHSHKSL
                     ARHLTQLRTLSDPPGGAGPGQDPSSRGRGRSHDHEETDDELGTNIDTMAIKKQKRCRK
                     IRPVSAFISGSPQDMESQLGSLGIPPGWFSGLGSSQPTASGSWEGLSELPTHGYKLRH
                     QTQGRPRPPRTTPPGPGRPSVPVPGPRQENGMATRLDEGLEDFFSRRVMDESSSYPRT
                     LRTMRPGPSEPPLPALQKRRRRGLFHFRRPRSFKGDRGPGSPTAGLLLPPPPPPPPTQ
                     ESPPSPDPPSLGNNSSPCWSPEEESSLLPGFGGARGSSFCRKMGTERLEAGDGAPAPG
                     TAQPPRVHGVALPGLGRTKGWSFDGKREGTDPDQEDSTQAWQKRRSSDDAGPGAWKPP
                     PPPQSSKPSFSAMRRAEATWHIAEESAPNHSCQSPSPASQDGEEEKDGALFPERMVPA
                     RNAKLQEPPIGPRPPKPVAVPRGRRAPQVPGGREEAESSSAAPGANKPWLRLGSQQDQ
                     EEPEGQVPSDLGRRTAPLKPKRTRRAQSCDKLEPDRRRPPDPAGVCGTSEPGTD"
     exon            49..143
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            144..194
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            195..254
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            255..370
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            371..468
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            469..539
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            540..613
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            614..689
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            690..778
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            779..873
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            874..960
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1070
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1148
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            1149..1225
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1330
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1400
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..1482
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1579
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            1580..1634
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1807
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            1808..1876
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..1970
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            1971..2069
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            2070..2198
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            2199..2312
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            2313..2488
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            2489..2576
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            2577..2711
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            2712..2775
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            2776..2984
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            2985..3085
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            3086..3401
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            3402..3530
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            3531..3597
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            3598..3687
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            3688..3806
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            3807..3987
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            3988..4107
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
     exon            4108..4452
                     /gene="Carmil3"
                     /gene_synonym="Lrrc16b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccgccat ggccaaggcc agcgtggagc tcacccgcga gctgcaagac agcatccgga
       61 ggtgcctgag ccagggggct gtgctccagc agcatcgagt gaaactagag acaaaaccca
      121 agaagttcga ggaccgagta ctggccctga cttcctggcg cctccacctc ttccccctta
      181 aagtcccagc caaggtagaa agctcattca atgtcctgga gatccgtgcc ttcaacacac
      241 tcagtcagaa ccagatcctg gtggagactg agcgtggtgt ggtgagcatg cggctgccgt
      301 cagctgagag tgtggaccag gtgacccggc atgtgagctc tgccctctcc aaggtctgcc
      361 ctggccctgg gtgtttgatc cggcgtggaa atgcagacac cccggagggt ccccgagaca
      421 catctcccaa ctctgaaaca tccacatcga ccactcacag tgtgtgtggt ggcttctccg
      481 agacctatgc tgccctatgt gactacaatg gactccactg ccgagaggag gtgcaatggg
      541 atgtggacac catctaccac gctgaggata accgagagtt caatcttttg gatttcagcc
      601 acttagagag ccgagatttg gcccttatgg tggctgccct ggcctacaac cagtggttca
      661 ccaaactcta ctgcaaagac ctgagactgg gctcagaagt gctagaacag gtgctacata
      721 ccctcagcaa gtcggggagc ctcgaagagc tggtgctgga caatgctggg cttaagacgg
      781 attttgtcca gaagctggcc ggggtgtttg gggagaacgg gagctgtgtg ctgcatgcgc
      841 tcactctgtc ccacaacccc atcgaggaca agggttttct cagtctgagc cagcagctcc
      901 tgtgctttcc cgccggcctc accaaactgt gcctggccaa gactgctgtt tcccctcgag
      961 ggctccaggc actgggccag accttcgggg ccaacccggc ctttgccagc tcccttcgat
     1021 acctggacct gagcaagaac ccaggcctgc ttgccacaga tgaggccaat gcactctata
     1081 gtttcttggc ccaacccaac gccttggtac acctggacct ttcagggacg gactgtgccg
     1141 ttgacttgct tctgggcgct ctacttcatg gctgctgctc ccacctcacc tacctcaacc
     1201 tggctcgaaa cagctgctcc cacaggaagg gccgggaggc cccgccagcc ttcaagcagt
     1261 tcttcagcag cgcctacacc ctgagccatg tcaacctgtc agccacaagg ctgcccctgg
     1321 aggccctcag ggcacttctt cagggcctct ccctcaacag tcacctcagt gatctgcacc
     1381 tggaccttag cagctgtgag ctccgctcag caggagccca ggccttgcag gagcagctgg
     1441 gggctgtcac ctgtataggc agcctagacc tgtctgataa tgggtttgac tcagacctcc
     1501 tgacgctggt gcctgcactt ggcaaaaaca aatccctcaa acacctattc ctggggaaga
     1561 acttcaatgt caaggccaag actttggaag agatccttca taagctggtc cagttgatcc
     1621 aggaagagga ttgttccctg cagtcactct cggtggcaga ctccaggctg aagcttcgca
     1681 ccagcatcct catcaacgcc ctgggcagca acacctgcct ggccaaggtg gacctgagcg
     1741 gcaacggcat ggaagacatc ggggccaaga tgctgtcgaa ggccctgcag ataaattctt
     1801 ccctcagaac tatcctatgg gaccggaaca atacatctgc cctgggcttc ctggacattg
     1861 caagggccct ggagagcaac cacacactgc gcttcatgtc cttccccgtg agcgacatct
     1921 cccaagctta ccgcagcgcc cctgagcgca cggaggatgt gtggcagaag atccagtggt
     1981 gcctggtgag gaacaaccac tcccagacat gccctcagga gcaagccttc aggctacagc
     2041 agggcctggt gaccagcagc gcagagcaaa tgctgcagcg gctatgtgga cgagtgcaag
     2101 aggaggtacg ggccctgaga ctatgtcccc tggagcctgt gcaagatgag ctgctgtatg
     2161 cccgagacct catcaaggat gccaagaact cccgggcgct gtttcccagt ctctgtgagc
     2221 tgggccacgt gttggccaat gatgggcctg tgcggcagag gctggagtcg gtagccagtg
     2281 aggtatccaa agctgtggac aaggagcttc aggtgatcct ggagtccatg gtcagcctaa
     2341 cacaggaatt atgccccgtg gccatgcggg tggcagaggg acacaacaag atgctgagca
     2401 acgtggcgga acgcgtcacc gtgccccgga acttcatccg cggagcgctg ctggagcagg
     2461 cgggacaaga cattcagaac aagctggacg aggtgaagct ctccgttgtc acctacttga
     2521 ccaactccat agtggacgag atcctgcagg agctgtacca ctcccacaag agcctggccc
     2581 ggcacctgac ccagctgagg acactgtcgg atccaccagg aggggccggc ccagggcaag
     2641 atccatcttc ccgaggcaga ggcaggagcc atgaccatga ggaaacagat gacgagcttg
     2701 ggaccaacat cgacaccatg gccatcaaaa agcagaaacg ctgccggaag atccggccag
     2761 tgtctgcctt catcagtggg agccctcagg acatggaaag ccaactggga agcttgggga
     2821 tccctcctgg ctggttctca ggacttggaa gcagccagcc cacagcgagt ggctcctggg
     2881 aaggcctatc tgagctacct acccatggct ataaactaag gcaccaaaca caagggaggc
     2941 cgaggcctcc caggactact ccaccaggac ccggtcggcc cagtgtgcca gtacctgggc
     3001 ctcgtcagga gaatgggatg gccacccgtc tagacgaggg gctggaggac ttcttcagca
     3061 gaagggtcat ggacgaaagc tccagctacc cccggactct gagaaccatg cggccaggcc
     3121 cctcagagcc accactgcct gcactccaga agaggaggcg gcgaggcctg tttcacttcc
     3181 gccggccccg gagcttcaag ggggacaggg gaccagggtc ccccactgct ggactcctcc
     3241 tccctccacc cccacctccg cccccaactc aggagagccc acccagtcca gaccccccaa
     3301 gccttggcaa taactcatct ccctgttgga gcccagagga ggagagcagc ctccttccag
     3361 gatttggagg ggcccgggga tcttccttct gcaggaagat gggcacagag aggttggagg
     3421 caggagacgg ggccccagcc cctgggacag cgcagccacc aagggtgcac ggcgttgccc
     3481 ttcctggctt gggaagaacc aaaggttgga gctttgatgg aaaacgagag ggcaccgacc
     3541 cagaccagga ggacagcacc caggcttggc agaaacggcg ctcttcggat gatgcagggc
     3601 ctggagcctg gaagccacca ccacccccac aaagctccaa gccaagcttc agcgccatgc
     3661 gccgagcaga ggccacgtgg cacatagctg aggagagtgc ccccaaccac agctgccaaa
     3721 gccctagccc agcttcccag gatggagaag aggaaaagga cggagcttta ttcccagaga
     3781 gaatggtccc agctcggaat gccaagctac aggagccccc cataggtcca cgtcccccta
     3841 agccagtggc tgtgcccagg ggccgtaggg ccccccaggt gccaggaggc agagaagagg
     3901 ctgagagcag cagtgctgcc ccaggagcca acaagccctg gctgagactg ggctcacagc
     3961 aagaccaaga ggagccagaa ggacaagtac cctctgacct gggccgtcga acagctcccc
     4021 tgaaacccaa gagaactcgg cgagcacagt cctgtgacaa actggaacct gatagaagac
     4081 ggccacctga ccctgcaggt gtctgtggaa ccagtgaacc aggaacagac tgacagctgc
     4141 tgaacgccct ccccagcctt cctcgacatg tgcctcataa ggactcaggc cccacccacc
     4201 cctgctcgcc catcccttgc cagcccttgt cctacagggc agcaccacta agaaggcatg
     4261 ggggagcagg agtggggact ggaagggagg gagtgacctg aagcagggaa gctgtcacac
     4321 ctgcctggag cttcctccac agagagcttt gggcagaggc tgtctcttcc ctggggggag
     4381 ggtgaacctc cgccccttta tgcccagggg ctctctcccc acttgtatag aattaaaaag
     4441 aaaatcactg tc
//
