LOCUS       NM_001005551            1790 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus carbonic anhydrase 5B (Car5b), mRNA; nuclear gene
            for mitochondrial product.
ACCESSION   NM_001005551 XM_217611
VERSION     NM_001005551.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1790)
  AUTHORS   Archambaud,C., Nahori,M.A., Soubigou,G., Becavin,C., Laval,L.,
            Lechat,P., Smokvina,T., Langella,P., Lecuit,M. and Cossart,P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   2  (bases 1 to 1790)
  AUTHORS   Shah,G.N., Hewett-Emmett,D., Grubb,J.H., Migas,M.C., Fleming,R.E.,
            Waheed,A. and Sly,W.S.
  TITLE     Mitochondrial carbonic anhydrase CA VB: differences in tissue
            distribution and pattern of evolution from those of CA VA suggest
            distinct physiological roles
  JOURNAL   Proc Natl Acad Sci U S A 97 (4), 1677-1682 (2000)
   PUBMED   10677517
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC081872.1.
            
            [WARNING] On Oct 18, 2024 this sequence was replaced by
            NM_001005551.3.
            
            On Aug 30, 2012 this sequence version replaced NM_001005551.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081872.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760384, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1790              BC081872.1         3-1792
FEATURES             Location/Qualifiers
     source          1..1790
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq14"
     gene            1..1790
                     /gene="Car5b"
                     /gene_synonym="Ca5b"
                     /note="carbonic anhydrase 5B"
                     /db_xref="GeneID:302669"
                     /db_xref="RGD:1549783"
     exon            1..197
                     /gene="Car5b"
                     /gene_synonym="Ca5b"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..1009
                     /gene="Car5b"
                     /gene_synonym="Ca5b"
                     /EC_number="4.2.1.1"
                     /note="CA-VB; carbonate dehydratase VB; carbonic anhydrase
                     VB, mitochondrial; carbonic anhydrase 5B, mitochondrial"
                     /codon_start=1
                     /product="carbonic anhydrase 5B, mitochondrial precursor"
                     /protein_id="NP_001005551.1"
                     /db_xref="GeneID:302669"
                     /db_xref="RGD:1549783"
                     /translation="MTVMSHLRVSLQVSSCTLLWRRFRVPRLVPLRSCSLYTCTYRTR
                     NRALPPLWENLDLVPAGDRQSPINIRWRDSVYDPGLKPLTISYDPATCLHIWNNGYSF
                     LVEFEDTTDKSVIEGGPLEHNYRLKQFHFHWGAIDAWGSEHTVDSKCYPAELHLVHWN
                     AVKFESFEDAALEENGLAVIGVFLKLGKHHKELQKLVDTLPSIKHKDTLVKFGSFDPS
                     CLMPTCPDYWTYSGSLTTPPLSESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKR
                     MVDNFRPLQPLMNRTVRSSFRHDYVLNIQVKPEPTASEVSP"
     exon            198..395
                     /gene="Car5b"
                     /gene_synonym="Ca5b"
                     /inference="alignment:Splign:2.1.0"
     exon            396..514
                     /gene="Car5b"
                     /gene_synonym="Ca5b"
                     /inference="alignment:Splign:2.1.0"
     exon            515..610
                     /gene="Car5b"
                     /gene_synonym="Ca5b"
                     /inference="alignment:Splign:2.1.0"
     exon            611..673
                     /gene="Car5b"
                     /gene_synonym="Ca5b"
                     /inference="alignment:Splign:2.1.0"
     exon            674..829
                     /gene="Car5b"
                     /gene_synonym="Ca5b"
                     /inference="alignment:Splign:2.1.0"
     exon            830..1765
                     /gene="Car5b"
                     /gene_synonym="Ca5b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccaggtttt aggctcctga gctgtttagt cattgctgag tgttccaagc taaagatgac
       61 agtgatgagt cacctgagag tgagtctaca agtctcttcg tgcacgctgc tgtggagacg
      121 gttccgggtt ccgaggttgg tgccactgag gtcctgcagt ctgtatacct gcacatacag
      181 aaccaggaat cgagccttac ctccactctg ggagaacttg gaccttgttc ctgctggtga
      241 tcggcagtca cccatcaaca tccgatggag ggacagtgtt tatgaccctg gcttaaaacc
      301 actcaccatt tcttatgacc cagccacctg cctccacatc tggaacaatg ggtactcctt
      361 tcttgtggaa tttgaagata ctacagataa atcagtaatt gagggaggac ccctggaaca
      421 taactaccga ctgaagcagt ttcattttca ctggggggcc atcgacgctt ggggctccga
      481 gcacactgtg gacagcaaat gctacccagc agagctgcac ttggtacatt ggaatgcagt
      541 caaatttgaa agttttgagg atgcagcact ggaagaaaat ggcttggctg tgataggtgt
      601 atttttaaag ctaggtaaac atcataaaga actgcagaaa ttggtggaca ctttgccatc
      661 aattaagcac aaggataccc tggtgaaatt tggatcattt gacccttcct gtctgatgcc
      721 tacttgccca gattactgga cctattctgg atctctcact acgcctcccc tctcagagtc
      781 tgttacctgg atcattaaga agcagccagt tgaggtcgac catgatcagc ttgaacagtt
      841 tcggaccctg cttttcacat ctgagggaga gaaagagaaa agaatggtgg acaacttccg
      901 cccacttcaa cctctgatga atcgcactgt ccgttcatcc ttccgccatg actatgtgct
      961 caatatacaa gtgaagcccg agccgactgc cagcgaagtc tccccctaag acagcatatt
     1021 taggcagcat cttgttttaa tgcatattag cttaaaattt caactagatg attttaaaac
     1081 ggcatttaat aatacttata tgtatacatt tctggttttt tttcttctaa ttttttgtaa
     1141 aaacatttca aaattcctct tcttataaag caaagacaaa gagacaaaac aagaaaaaca
     1201 aaaacctgta acaaaacaac atcaaattac ctaaggtcac cctttctcat gacaggatta
     1261 aggcagagga atcttcatta acagttaaat ctcttgaatc tatttctcag aaagtcagat
     1321 gaacagttta gtttcccctt ggttaaatgg aagcttagtg tgagtgtctg atcttgattt
     1381 ttctgtttgg gcctaattca ggatcttaac ccacaaggag aggttcttgg gaattttact
     1441 taacaataac tcccttttgc tcaaactgta aattgtctca tctttcagtg ttagtcccac
     1501 tcttaggagg cgaatggctt tcaaaggtta ggcatacact tactggtttt aatttgtgtc
     1561 ttttttttgt tttttttttt tgttttttaa agataaggtc atactattta gccctgacta
     1621 tcctggaaat cactatgcaa accagtccag acttgaactc acagaggtct gtctgtcttt
     1681 gcctcctaag tgctgggatt aaaggcttgt gccaccacag ccagctttca tttgtcttat
     1741 caaatatatt tgctctttga cttataaaaa aaaaaaaaaa aaaaaaaaaa
//
