LOCUS       NM_017164               1222 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus capping actin protein of muscle Z-line subunit
            alpha 3 (Capza3), mRNA.
ACCESSION   NM_017164
VERSION     NM_017164.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1222)
  AUTHORS   Javadian-Elyaderani,S., Ghaedi,K., Tavalaee,M., Rabiee,F.,
            Deemeh,M.R. and Nasr-Esfahani,M.H.
  TITLE     Diagnosis of genetic defects through parallel assessment of PLCzeta
            and CAPZA3 in infertile men with history of failed oocyte
            activation
  JOURNAL   Iran J Basic Med Sci 19 (3), 281-289 (2016)
   PUBMED   27114798
REFERENCE   2  (bases 1 to 1222)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 1222)
  AUTHORS   Geyer,C.B., Inselman,A.L., Sunman,J.A., Bornstein,S., Handel,M.A.
            and Eddy,E.M.
  TITLE     A missense mutation in the Capza3 gene and disruption of F-actin
            organization in spermatids of repro32 infertile male mice
  JOURNAL   Dev Biol 330 (1), 142-152 (2009)
   PUBMED   19341723
REFERENCE   4  (bases 1 to 1222)
  AUTHORS   Robledo,R.F., Ciciotte,S.L., Gwynn,B., Sahr,K.E., Gilligan,D.M.,
            Mohandas,N. and Peters,L.L.
  TITLE     Targeted deletion of alpha-adducin results in absent beta- and
            gamma-adducin, compensated hemolytic anemia, and lethal
            hydrocephalus in mice
  JOURNAL   Blood 112 (10), 4298-4307 (2008)
   PUBMED   18723693
REFERENCE   5  (bases 1 to 1222)
  AUTHORS   Hurst,S., Howes,E.A., Coadwell,J. and Jones,R.
  TITLE     Expression of a testis-specific putative actin-capping protein
            associated with the developing acrosome during rat spermiogenesis
  JOURNAL   Mol Reprod Dev 49 (1), 81-91 (1998)
   PUBMED   9406198
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC078870.1.
            
            On Nov 23, 2005 this sequence version replaced NM_017164.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC078870.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1222              BC078870.1         1-1222
FEATURES             Location/Qualifiers
     source          1..1222
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q44"
     gene            1..1222
                     /gene="Capza3"
                     /gene_synonym="Cappa3"
                     /note="capping actin protein of muscle Z-line subunit
                     alpha 3"
                     /db_xref="GeneID:29324"
                     /db_xref="RGD:2271"
     exon            1..1214
                     /gene="Capza3"
                     /gene_synonym="Cappa3"
                     /inference="alignment:Splign:2.1.0"
     CDS             104..1003
                     /gene="Capza3"
                     /gene_synonym="Cappa3"
                     /note="capping actin protein of muscle Z-line alpha
                     subunit 3; capZ alpha-3; capping protein alpha 3; capping
                     protein (actin filament) muscle Z-line, alpha 3"
                     /codon_start=1
                     /product="F-actin-capping protein subunit alpha-3"
                     /protein_id="NP_058860.2"
                     /db_xref="GeneID:29324"
                     /db_xref="RGD:2271"
                     /translation="MSLSVLSRQDKEKVIHRLLIQAPPGEFVNAFDDLCLLIRDEKLM
                     HHQGECAGHQHCQKYCVPLCIDGNPVLLSHHNVMGDFRFFDYQSKLSFRFDLLQNQLR
                     DIQSHGIIRNETEYLRSVVMCALKLYVNDHYPNGNCNVLRKTVKNKEFLIACIEDHSY
                     DNGECWNGLWKSKWIFQVNPFLTQVTGRIFVQAHYFRCVNLHVEVSKDLKESLEVVNQ
                     AQLALSFARLVEEQENKFQAAVIEELQELSNEALRKILRRDLPVTRTLIDWQRILSDL
                     NLVMYPKLGYVIYSRSVLCNWII"
ORIGIN      
        1 cttgaatgat taacaccttg aatgggcaag atatcccatg gatcctcttc tcaccctgtg
       61 aacacccttc acttcagaag ctttgcttct cctgaaacta gacatgtcac tcagcgtctt
      121 aagtaggcaa gacaaagaaa aggtcatcca cagactctta atccaggctc ctcctgggga
      181 attcgtgaat gcctttgatg atctctgtct gcttatccga gatgagaagc tcatgcacca
      241 ccagggtgag tgcgcaggtc atcagcactg ccaaaaatac tgtgtcccac tctgcatcga
      301 tggcaatcca gtcctcttgt ctcaccacaa tgtgatgggt gacttccggt tctttgacta
      361 ccagagcaaa ctttctttca ggtttgacct gctccagaat cagctgagag acatccaaag
      421 ccacggaatc attcggaatg agaccgagta cctgagatct gttgttatgt gtgccttaaa
      481 actctacgtg aacgatcact acccaaacgg caactgcaac gtgctgagga aaacagtcaa
      541 aaacaaggag ttcttaatag cttgcattga agaccacagc tatgacaatg gagagtgttg
      601 gaatggtctt tggaagtcta agtggatctt ccaggtaaac ccgtttctaa cccaagtgac
      661 aggaaggatt tttgtgcaag ctcactactt cagatgtgtc aaccttcatg ttgaagtctc
      721 caaggacctc aaggagagct tggaggtggt caaccaagcc cagttggctc tcagtttcgc
      781 aaggcttgtg gaagaacaag aaaataagtt tcaagctgct gtaatagaag aactacagga
      841 gttgtctaat gaagccctga ggaaaatatt acggagggat cttccagtga cacgcacttt
      901 gattgactgg caacggatcc tctctgactt gaatctggtg atgtacccca aattaggata
      961 cgttatttac tccaggagtg tgctgtgcaa ctggataata taaaaggttg ctgctccaca
     1021 ttatcgtctc aagccaaagt gctttctggg aagtcagtgc ttagatagtg ctgagaagct
     1081 cttggactag tactaagcct gtctttagcc tataccagtt tgaagagggg gaagaacaag
     1141 aaatcatgtt atccagtcag tattcaccaa catggcaaaa agggtaaaaa tacatttcat
     1201 aatgttaact gtcaaaaaaa aa
//
