LOCUS       NM_001013086            1500 bp    mRNA    linear   ROD 15-MAR-2025
DEFINITION  Rattus norvegicus capping actin protein, gelsolin like (Capg),
            mRNA.
ACCESSION   NM_001013086 XM_216166
VERSION     NM_001013086.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1500)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1500)
  AUTHORS   Abonnenc,M., Nabeebaccus,A.A., Mayr,U., Barallobre-Barreiro,J.,
            Dong,X., Cuello,F., Sur,S., Drozdov,I., Langley,S.R., Lu,R.,
            Stathopoulou,K., Didangelos,A., Yin,X., Zimmermann,W.H., Shah,A.M.,
            Zampetaki,A. and Mayr,M.
  TITLE     Extracellular matrix secretion by cardiac fibroblasts: role of
            microRNA-29b and microRNA-30c
  JOURNAL   Circ Res 113 (10), 1138-1147 (2013)
   PUBMED   24006456
REFERENCE   3  (bases 1 to 1500)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (bases 1 to 1500)
  AUTHORS   Hubert,T., Van Impe,K., Vandekerckhove,J. and Gettemans,J.
  TITLE     The actin-capping protein CapG localizes to microtubule-dependent
            organelles during the cell cycle
  JOURNAL   Biochem Biophys Res Commun 380 (1), 166-170 (2009)
   PUBMED   19166812
REFERENCE   5  (bases 1 to 1500)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 1500)
  AUTHORS   Trost,M., English,L., Lemieux,S., Courcelles,M., Desjardins,M. and
            Thibault,P.
  TITLE     The phagosomal proteome in interferon-gamma-activated macrophages
  JOURNAL   Immunity 30 (1), 143-154 (2009)
   PUBMED   19144319
REFERENCE   7  (bases 1 to 1500)
  AUTHORS   Hubert,T., Van Impe,K., Vandekerckhove,J. and Gettemans,J.
  TITLE     The F-actin filament capping protein CapG is a bona fide nucleolar
            protein
  JOURNAL   Biochem Biophys Res Commun 377 (2), 699-704 (2008)
   PUBMED   18938132
REFERENCE   8  (bases 1 to 1500)
  AUTHORS   Van Impe,K., Hubert,T., De Corte,V., Vanloo,B., Boucherie,C.,
            Vandekerckhove,J. and Gettemans,J.
  TITLE     A new role for nuclear transport factor 2 and Ran: nuclear import
            of CapG
  JOURNAL   Traffic 9 (5), 695-707 (2008)
   PUBMED   18266911
REFERENCE   9  (bases 1 to 1500)
  AUTHORS   Witke,W., Li,W., Kwiatkowski,D.J. and Southwick,F.S.
  TITLE     Comparisons of CapG and gelsolin-null macrophages: demonstration of
            a unique role for CapG in receptor-mediated ruffling, phagocytosis,
            and vesicle rocketing
  JOURNAL   J Cell Biol 154 (4), 775-784 (2001)
   PUBMED   11514591
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079104.1.
            
            On Apr 20, 2005 this sequence version replaced XM_216166.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079104.1, SRR8487230.30007.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132291, SAMEA5756307
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1500
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q32"
     gene            1..1500
                     /gene="Capg"
                     /note="capping actin protein, gelsolin like"
                     /db_xref="GeneID:297339"
                     /db_xref="RGD:1311724"
     exon            1..292
                     /gene="Capg"
                     /inference="alignment:Splign:2.1.0"
     exon            293..328
                     /gene="Capg"
                     /inference="alignment:Splign:2.1.0"
     CDS             306..1355
                     /gene="Capg"
                     /note="actin regulatory protein CAP-G; capping protein
                     (actin filament), gelsolin-like"
                     /codon_start=1
                     /product="macrophage-capping protein"
                     /protein_id="NP_001013104.1"
                     /db_xref="GeneID:297339"
                     /db_xref="RGD:1311724"
                     /translation="MYTPIPQSGSPFPASVQDPGLHIWRVEKLKPVPIARENHGIFFS
                     GDSYLVLHNGPEEASHLHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNE
                     SDLFMSYFPQGLKYREGGVESAFHKTTSGTTPAAIRKLYQVKGKKNIRATERALSWDS
                     FNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIITDGEEP
                     AEMIQVLGPKPALKEGNPEEDITADQTNAQAAALYKVSDATGQMNLTKVADSSPFASE
                     LLIPDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVADGFISRMRYSPNTQVEILPQ
                     GRESPIFKQFFKDWK"
     exon            329..501
                     /gene="Capg"
                     /inference="alignment:Splign:2.1.0"
     exon            502..656
                     /gene="Capg"
                     /inference="alignment:Splign:2.1.0"
     exon            657..824
                     /gene="Capg"
                     /inference="alignment:Splign:2.1.0"
     exon            825..974
                     /gene="Capg"
                     /inference="alignment:Splign:2.1.0"
     exon            975..1067
                     /gene="Capg"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1200
                     /gene="Capg"
                     /inference="alignment:Splign:2.1.0"
     exon            1201..1477
                     /gene="Capg"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggctttcc ttgcccatct gactttaaat tgctcagaat ttgccttgcc tgaggctgct
       61 gtgatgagac cctgtcaggc tttaaccttc cagtggtcgt gtccgggaaa gggcagtctt
      121 ccatcagcat ggctcagtct tggagcttgc tttccagaat cttagacctc tgagttctga
      181 gcctccccat gggtggggca ggtgggcggg acagcccagt ggagaagagg gaagtcagaa
      241 gccagcgtgg ggcaggctga gactagtcgg agaagaaaag gccggtggag aggtctgaaa
      301 acagcatgta cacgcccatc cctcagagtg gctctccatt cccagcctca gtccaagacc
      361 caggcctaca catatggcgt gtggagaagc tgaagccggt gcccatagca cgagagaacc
      421 atggcatctt tttttctggg gattcctacc tagtgcttca caatggcccg gaagaggcct
      481 cccatctgca cctgtggata ggccagcagt catcgcgcga tgagcagggg gcctgcgctg
      541 tgctagctgt gcacctcaac accctgctgg gggagcggcc tgtgcagcac cgtgaggttc
      601 aagggaacga gtccgacctc ttcatgagct acttcccaca aggcctcaag tatcgggagg
      661 gtggcgtgga gtcggcgttc cacaagacaa cctcgggcac cacgccagca gccatcagga
      721 agctctacca ggttaagggg aagaagaaca tccgtgcgac cgagagggct ctgagctggg
      781 acagcttcaa cactggggac tgcttcatcc tggacctggg tcagaacatc tttgcctggt
      841 gtggtggcaa gtccaacatc ctggagcgca acaaggcgag agacctggcc ctggccatcc
      901 gggacagcga gcggcagggg aaggcccagg tggagatcat cactgacgga gaggagccag
      961 ccgagatgat ccaggttctg ggccccaagc ctgctctgaa ggagggcaac cctgaggagg
     1021 acattacagc ggaccagacc aacgcccagg ctgcagccct gtataaggtc tctgatgcca
     1081 ctggacagat gaatctgacc aaggtggctg actccagccc gtttgcctct gaactgctaa
     1141 ttccagatga ctgctttgtt ctggacaacg ggctatgtgg caaaatctac atctggaagg
     1201 ggagaaaagc caatgagaag gagcggcagg cggccctcca agtggctgat ggcttcatct
     1261 ctcgaatgag atattcccca aacactcagg tggagattct gccccagggc cgagagagtc
     1321 ccatcttcaa gcagttcttc aaggactgga agtgagggtg ggtgtcccca tccctgctct
     1381 cctgccccca ccacctgcct gcttgtttcc cctctggctg ctgagtcaga actgaggggc
     1441 cctctggatg ctcaataaag gacacgttct gttcccaaaa aaaaaaaaaa aaaaaaaaaa
//
