LOCUS       NM_053874               1636 bp    mRNA    linear   ROD 26-APR-2024
DEFINITION  Rattus norvegicus cyclase associated actin cytoskeleton regulatory
            protein 2 (Cap2), mRNA.
ACCESSION   NM_053874
VERSION     NM_053874.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1636)
  AUTHORS   Pelucchi,S., Vandermeulen,L., Pizzamiglio,L., Aksan,B., Yan,J.,
            Konietzny,A., Bonomi,E., Borroni,B., Padovani,A., Rust,M.B., Di
            Marino,D., Mikhaylova,M., Mauceri,D., Antonucci,F., Edefonti,V.,
            Gardoni,F., Di Luca,M. and Marcello,E.
  TITLE     Cyclase-associated protein 2 dimerization regulates cofilin in
            synaptic plasticity and Alzheimer's disease
  JOURNAL   Brain Commun 2 (2), fcaa086 (2020)
   PUBMED   33094279
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1636)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   3  (bases 1 to 1636)
  AUTHORS   Ishimaru,Y., Yasuoka,A., Asano-Miyoshi,M., Abe,K. and Emori,Y.
  TITLE     An actin-binding protein, CAP, is expressed in a subset of rat
            taste bud cells
  JOURNAL   Neuroreport 12 (2), 233-235 (2001)
   PUBMED   11209926
REFERENCE   4  (bases 1 to 1636)
  AUTHORS   Swiston,J., Hubberstey,A., Yu,G. and Young,D.
  TITLE     Differential expression of CAP and CAP2 in adult rat tissues
  JOURNAL   Gene 165 (2), 273-277 (1995)
   PUBMED   8522189
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U31935.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U31935.1, SRR8487226.56995.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1636
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..1636
                     /gene="Cap2"
                     /note="cyclase associated actin cytoskeleton regulatory
                     protein 2"
                     /db_xref="GeneID:116653"
                     /db_xref="RGD:620310"
     exon            1..46
                     /gene="Cap2"
                     /inference="alignment:Splign:2.1.0"
     exon            47..168
                     /gene="Cap2"
                     /inference="alignment:Splign:2.1.0"
     CDS             48..1481
                     /gene="Cap2"
                     /note="CAP 2; CAP, adenylate cyclase-associated protein,
                     2"
                     /codon_start=1
                     /product="adenylyl cyclase-associated protein 2"
                     /protein_id="NP_446326.1"
                     /db_xref="GeneID:116653"
                     /db_xref="RGD:620310"
                     /translation="MADMLGLMQRLEFAVSRLERLSSGLHEPPGGCGEVNSLSRGIVA
                     PSVEAFDKLINSMVAEFLKNSRVLAGDVETHAEMVHGAFQAQRAFLLMVSQHQQPQEN
                     EVAVLLKPISEKIQEIQTFRERNRGSDMFNHLSAVSESIAALGWIAVSPKPGPYVKEM
                     NDAATFYTNRVLRDYKHSDLRHVDWVRSYLKIWSELQAYIKEHHTTGLTWSKTGPVAS
                     TASAFSILSSGPGLPPPPPPPPPPGPPPPFENEGGKEEPSPSRSALFAQLNQGEAITK
                     GLRHVTDDKKIYKNPSLRAQGQIRSPTKTRTPSPTSSKSNSPQKHAPVLELEGKKWRV
                     EYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLVFDHVVGIV
                     EVINSKDIQIQVMGRVPTISINKTEGCHLYLSKDALDCEIVSAKSSEMNVLVPQGDDY
                     REFPIPEQFKTIWDGSKLITEPAEIMA"
     exon            169..272
                     /gene="Cap2"
                     /inference="alignment:Splign:2.1.0"
     exon            273..350
                     /gene="Cap2"
                     /inference="alignment:Splign:2.1.0"
     exon            351..494
                     /gene="Cap2"
                     /inference="alignment:Splign:2.1.0"
     exon            495..580
                     /gene="Cap2"
                     /inference="alignment:Splign:2.1.0"
     exon            581..686
                     /gene="Cap2"
                     /inference="alignment:Splign:2.1.0"
     exon            687..876
                     /gene="Cap2"
                     /inference="alignment:Splign:2.1.0"
     exon            877..1049
                     /gene="Cap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1173
                     /gene="Cap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1174..1256
                     /gene="Cap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1257..1397
                     /gene="Cap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1398..1636
                     /gene="Cap2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagctggctt tgcatcaccg aagctgggac ctgggctgta cagcagaatg gcagacatgc
       61 tgggactgat gcagaggctg gaattcgccg tcagccggct cgagcggctg tcctcagggt
      121 tacacgaacc tcccggaggc tgtggggaag ttaacagcct cagtagaggc atagtagcac
      181 catccgtgga agcctttgac aaactgataa acagtatggt ggccgagttc ttaaagaaca
      241 gccgagtcct tgctggcgac gtagagactc acgcggaaat ggtacatggt gctttccagg
      301 cgcagcgtgc ttttcttctc atggtctctc agcaccaaca accccaggag aatgaagttg
      361 ctgtccttct gaaacccata tcggagaaga ttcaagaaat acagacattc cgcgagagaa
      421 accgggggag cgacatgttc aaccacctct cggcagtcag cgagagcatc gccgccctgg
      481 ggtggatagc cgtgtctccc aaacctggtc catatgtcaa ggagatgaac gacgccgcca
      541 ccttttacac taacagggtc ctgagggact acaagcacag cgatctgcgc cacgtggatt
      601 gggtgaggtc ctatctcaag atctggagcg aactgcaagc ctacatcaag gagcaccaca
      661 ccacaggcct cacttggagt aaaactggtc ctgtagcatc cacagcatca gcgttttcca
      721 ttctctcctc tgggcccggt ctccctccac cacctccacc accacctcct cctggaccac
      781 ctcccccttt tgagaatgag ggcggaaagg aggagccctc cccgtctcgc tcagctttgt
      841 ttgcccagct aaatcaggga gaagccatca caaaagggct ccgacatgtc acggacgaca
      901 agaaaatata caagaatccc agcttgaggg cccaaggaca aattcgatct ccaaccaaaa
      961 cccgcacgcc gagccctaca tcttcaaaat cgaattctcc tcagaaacat gctccagtgt
     1021 tggagttgga agggaagaaa tggagagtgg aataccaaga ggacaggaat gaccttgtca
     1081 tctcagagac tgagctaaaa caagtggcgt acattttcaa atgtgacaaa tccactcttc
     1141 agataaaggg aaaagtaaac tccatcaccg tcgataactg caagaagttt ggcctggtgt
     1201 tcgaccatgt ggtgggcatc gtggaagtga tcaactccaa ggacattcag atccaggtaa
     1261 tggggagagt gccaacaatc tccattaata agacagaagg atgccacctg tacctcagta
     1321 aagatgcgct agactgtgag atcgtgagcg ccaagtcgtc cgagatgaat gtcctggtcc
     1381 ctcagggtga cgattataga gaatttccca ttcctgagca gttcaagacg atatgggacg
     1441 gatccaagct catcaccgaa cctgcagaaa tcatggcctg acctccaaga gatatccttc
     1501 cccgagtccc tccagctggc agaagcaaac agctaatagg agctagattt caccatagcc
     1561 ccggcgtcca tgtcagcgtc ctgcagttct gtgccgtgga aaacagtttc ttttctggca
     1621 ggcttttatg ggcgtt
//
