LOCUS       NP_001138312            1269 aa            linear   ROD 24-JUN-2024
DEFINITION  calmodulin-regulated spectrin-associated protein 3 [Rattus
            norvegicus].
ACCESSION   NP_001138312 XP_001063790 XP_001069418
VERSION     NP_001138312.1
DBSOURCE    REFSEQ: accession NM_001144840.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 1269)
  AUTHORS   Zenker,J., White,M.D., Templin,R.M., Parton,R.G., Thorn-Seshold,O.,
            Bissiere,S. and Plachta,N.
  TITLE     A microtubule-organizing center directing intracellular transport
            in the early mouse embryo
  JOURNAL   Science 357 (6354), 925-928 (2017)
   PUBMED   28860385
REFERENCE   2  (residues 1 to 1269)
  AUTHORS   Wilson,R., Geyer,S.H., Reissig,L., Rose,J., Szumska,D., Hardman,E.,
            Prin,F., McGuire,C., Ramirez-Solis,R., White,J., Galli,A.,
            Tudor,C., Tuck,E., Mazzeo,C.I., Smith,J.C., Robertson,E.,
            Adams,D.J., Mohun,T. and Weninger,W.J.
  TITLE     Highly variable penetrance of abnormal phenotypes in embryonic
            lethal knockout mice
  JOURNAL   Wellcome Open Res 1, 1 (2017)
   PUBMED   27996060
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 1269)
  AUTHORS   Wang,J., Xu,H., Jiang,Y., Takahashi,M., Takeichi,M. and Meng,W.
  TITLE     CAMSAP3-dependent microtubule dynamics regulates Golgi assembly in
            epithelial cells
  JOURNAL   J Genet Genomics 44 (1), 39-49 (2017)
   PUBMED   28089391
REFERENCE   4  (residues 1 to 1269)
  AUTHORS   Noordstra,I., Liu,Q., Nijenhuis,W., Hua,S., Jiang,K., Baars,M.,
            Remmelzwaal,S., Martin,M., Kapitein,L.C. and Akhmanova,A.
  TITLE     Control of apico-basal epithelial polarity by the microtubule
            minus-end-binding protein CAMSAP3 and spectraplakin ACF7
  JOURNAL   J Cell Sci 129 (22), 4278-4288 (2016)
   PUBMED   27802168
REFERENCE   5  (residues 1 to 1269)
  AUTHORS   Ning,W., Yu,Y., Xu,H., Liu,X., Wang,D., Wang,J., Wang,Y. and
            Meng,W.
  TITLE     The CAMSAP3-ACF7 Complex Couples Noncentrosomal Microtubules with
            Actin Filaments to Coordinate Their Dynamics
  JOURNAL   Dev Cell 39 (1), 61-74 (2016)
   PUBMED   27693509
REFERENCE   6  (residues 1 to 1269)
  AUTHORS   Jiang,K., Hua,S., Mohan,R., Grigoriev,I., Yau,K.W., Liu,Q.,
            Katrukha,E.A., Altelaar,A.F., Heck,A.J., Hoogenraad,C.C. and
            Akhmanova,A.
  TITLE     Microtubule minus-end stabilization by polymerization-driven CAMSAP
            deposition
  JOURNAL   Dev Cell 28 (3), 295-309 (2014)
   PUBMED   24486153
REFERENCE   7  (residues 1 to 1269)
  AUTHORS   Tanaka,N., Meng,W., Nagae,S. and Takeichi,M.
  TITLE     Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific
            organization of noncentrosomal microtubules
  JOURNAL   Proc Natl Acad Sci U S A 109 (49), 20029-20034 (2012)
   PUBMED   23169647
REFERENCE   8  (residues 1 to 1269)
  AUTHORS   Hendrickx,A., Beullens,M., Ceulemans,H., Den Abt,T., Van Eynde,A.,
            Nicolaescu,E., Lesage,B. and Bollen,M.
  TITLE     Docking motif-guided mapping of the interactome of protein
            phosphatase-1
  JOURNAL   Chem Biol 16 (4), 365-371 (2009)
   PUBMED   19389623
REFERENCE   9  (residues 1 to 1269)
  AUTHORS   Meng,W., Mushika,Y., Ichii,T. and Takeichi,M.
  TITLE     Anchorage of microtubule minus ends to adherens junctions regulates
            epithelial cell-cell contacts
  JOURNAL   Cell 135 (5), 948-959 (2008)
   PUBMED   19041755
REFERENCE   10 (residues 1 to 1269)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474084.1.
            
            On or before Jan 26, 2009 this sequence version replaced
            XP_001063790.1, XP_001069418.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132269,
                              SAMD00132291 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1269
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12p12"
     Protein         1..1269
                     /product="calmodulin-regulated spectrin-associated protein
                     3"
                     /calculated_mol_wt=136607
     Region          230..312
                     /region_name="CAMSAP_CH"
                     /note="CAMSAP CH domain; pfam11971"
                     /db_xref="CDD:432229"
     Region          604..661
                     /region_name="CAMSAP_CC1"
                     /note="Spectrin-binding region of Ca2+-Calmodulin;
                     pfam17095"
                     /db_xref="CDD:465344"
     Region          1129..1257
                     /region_name="CAMSAP_CKK"
                     /note="Microtubule-binding calmodulin-regulated
                     spectrin-associated; smart01051"
                     /db_xref="CDD:198119"
     CDS             1..1269
                     /gene="Camsap3"
                     /gene_synonym="RGD1307246"
                     /coded_by="NM_001144840.1:114..3923"
                     /db_xref="GeneID:689074"
                     /db_xref="RGD:1597412"
ORIGIN      
        1 mveaapagsg plrrtflvpe iksldqydfs rakaaaslaw vlraafggae hvppelwepf
       61 ytdqyaqehv kppvtrllls aelycrawrq alpqlepsps psallallar rgtvpslpeh
      121 pvreadlkhq pilmgahlav idalmvafsf ewtktlpgpl alsslehkll fwvdttvrrl
      181 qekteqeatq raspaapldg aspaqpshai afclkesgnk ppmiryrkdr aiarrapcfp
      241 nvttlqdlas gaalaatihc ycpqllrlee vclkdpmsva dslynlqlvq dfcashlprg
      301 cplsledlly vppplkvnlv vllaemymcf evlkpdfvqa kdlpdghavs prntetvpsq
      361 nnsgssspvf nfrhpllspg gpqsplrgst gslksspsms hmealgkawn rqlsrplsqa
      421 vsfstpfgld sdvdvvmgdp vllrsvssds lgpprpalts srnsaqpppe sgdlptieea
      481 lqiihsaepr llpdgaadgs fylhspegls kpplaspypp egaskplsdg lnkapiyish
      541 penpskpspc sagetlkppp psegspkava sspaannsev kmtsfaerkk qlvkaeaesg
      601 tgsptstpva pealssemse lgarleekrr aieaqkrrie aifakhrqrl gksaflqvqp
      661 reaageaeee aelgsvpgge rpagegqgep ssrpksvtfs pdlgpippeg lgdynravsk
      721 lsaalsslqr dmqrltdqqq rllappeapg papppaawvi pgpatgpkaa spsparrapa
      781 arrspgpgps ptprspkhar paelklaplt rvltpphdvd slphlrkfsp sqvpvqtrss
      841 illsegtppe epttkpalie iplaslgepa aeeegdgspp gaedsleeea ssegeprsgl
      901 gffykdedkp edemaqkras llerqqrrae earrrkqwqe aekeqkreea arlaqeeapg
      961 lalsapvapa apvatlapat ramapaeeev gprrgdftrl eyerraqlkl mddldkvlrp
     1021 rasgtggpgr ggrratrprs gccddsalar spargllgsr lskvysqstl slstvaneap
     1081 nnlgvkrsts rapspsglms psrlpgsrer dwengsnass pasvpeytgp rlykepsaks
     1141 nkfiihnals hcclagkvne pqknrileei ekskanhfli lfrdsscqfr alytlsgete
     1201 elsrlagygp rtvtpamveg iykynsdrkr ftqipaktms msvdaftiqg hlwqskkptt
     1261 pkkgggtpk
//
