LOCUS       NM_001398726            1377 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus calcium modulating ligand (Camlg), transcript
            variant 1, mRNA.
ACCESSION   NM_001398726 XM_006253658
VERSION     NM_001398726.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1377)
  AUTHORS   Lan,X., Fu,H., Li,G., Zeng,W., Lin,X., Zhu,Y., Liu,M. and Chen,P.
  TITLE     TMUB1 Inhibits BRL-3A Hepatocyte Proliferation by Interfering with
            the Binding of CAML to Cyclophilin B through its TM1 Hydrophobic
            Domain
  JOURNAL   Sci Rep 8 (1), 9917 (2018)
   PUBMED   29967478
  REMARK    GeneRIF: CAML role in the hepatocyte proliferation.TMUB1 regulates
            hepatocyte proliferation by interacting with CAML and further
            interferes with the binding of CAML to cyclophilin B.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1377)
  AUTHORS   Yamamoto,Y. and Sakisaka,T.
  TITLE     Molecular machinery for insertion of tail-anchored membrane
            proteins into the endoplasmic reticulum membrane in mammalian cells
  JOURNAL   Mol Cell 48 (3), 387-397 (2012)
   PUBMED   23041287
REFERENCE   3  (bases 1 to 1377)
  AUTHORS   Peng,Z., Shi,T. and Ma,D.
  TITLE     RNF122: a novel ubiquitin ligase associated with calcium-modulating
            cyclophilin ligand
  JOURNAL   BMC Cell Biol 11, 41 (2010)
   PUBMED   20553626
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1377)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 1377)
  AUTHORS   Brandenburg,L.O., Varoga,D., Nicolaeva,N., Leib,S.L., Podschun,R.,
            Wruck,C.J., Wilms,H., Lucius,R. and Pufe,T.
  TITLE     Expression and regulation of antimicrobial peptide rCRAMP after
            bacterial infection in primary rat meningeal cells
  JOURNAL   J Neuroimmunol 217 (1-2), 55-64 (2009)
   PUBMED   19879657
REFERENCE   6  (bases 1 to 1377)
  AUTHORS   Tran,D.D., Russell,H.R., Sutor,S.L., van Deursen,J. and Bram,R.J.
  TITLE     CAML is required for efficient EGF receptor recycling
  JOURNAL   Dev Cell 5 (2), 245-256 (2003)
   PUBMED   12919676
REFERENCE   7  (bases 1 to 1377)
  AUTHORS   Larramendy,M.L., Niini,T., Elonen,E., Nagy,B., Ollila,J.,
            Vihinen,M. and Knuutila,S.
  TITLE     Overexpression of translocation-associated fusion genes of FGFRI,
            MYC, NPMI, and DEK, but absence of the translocations in acute
            myeloid leukemia. A microarray analysis
  JOURNAL   Haematologica 87 (6), 569-577 (2002)
   PUBMED   12031912
REFERENCE   8  (bases 1 to 1377)
  AUTHORS   Lee,S.J., Drabik,K. and Benveniste,E.N.
  TITLE     Cloning of rat calcium-modulating cyclophilin ligand
  JOURNAL   DNA Seq 12 (3), 209-213 (2001)
   PUBMED   11762198
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On Dec 22, 2021 this sequence version replaced XM_006253658.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC076377.1, SRR26643286.42517.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMN12840108 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-250               JAXUCZ010000017.1  9008459-9008708     c
            251-714             JAXUCZ010000017.1  9006478-9006941     c
            715-780             JAXUCZ010000017.1  9003245-9003310     c
            781-1377            JAXUCZ010000017.1  8997868-8998464     c
FEATURES             Location/Qualifiers
     source          1..1377
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..1377
                     /gene="Camlg"
                     /gene_synonym="Caml"
                     /note="calcium modulating ligand"
                     /db_xref="GeneID:81715"
                     /db_xref="RGD:69297"
     exon            1..250
                     /gene="Camlg"
                     /gene_synonym="Caml"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..972
                     /gene="Camlg"
                     /gene_synonym="Caml"
                     /note="isoform 1 is encoded by transcript variant 1;
                     calcium signal-modulating cyclophilin ligand; guided entry
                     of tail-anchored proteins factor CAMLG"
                     /codon_start=1
                     /product="guided entry of tail-anchored proteins factor
                     CAMLG isoform 1"
                     /protein_id="NP_001385655.1"
                     /db_xref="GeneID:81715"
                     /db_xref="RGD:69297"
                     /translation="MEPMPSATDGGDRSATPSGLSASQRRAELRRRKLLMNSEQRINR
                     IMGFHRPGSGAEEENQTKSKPLDSDILNPLGVPSVSKRVVLGDSVDGGVTDYQPSGGA
                     DIRGAQLGDKLDSFIKAPECSSKDGVELRQRNRGDLTADSAPRGSHHGLEQYLSRFEE
                     AMKLRKQLISEKPSQEDGRTTEEFDSFRIFRLVGCALLALVVRAFVCKYLSIFAPFLT
                     LQLAYMGLYKYFPKGEKKVKTTVLTAALLLSGIPAEVINRSMDTYSKMGEVFTDLCVY
                     FFTFIFCHEVLEYWGPEVP"
     exon            251..714
                     /gene="Camlg"
                     /gene_synonym="Caml"
                     /inference="alignment:Splign:2.1.0"
     exon            715..780
                     /gene="Camlg"
                     /gene_synonym="Caml"
                     /inference="alignment:Splign:2.1.0"
     exon            781..1377
                     /gene="Camlg"
                     /gene_synonym="Caml"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtgggagtg ggaccgaact ctgaggccct gcctgaagtc atcctcgcct ttactgtcac
       61 cctgaaccag gcagtagaga aagcatggag ccgatgcctt cggccaccga cggcggggac
      121 aggtccgcga cgccctcggg cctgtcggct tctcagcgtc gagcagagct gcggaggagg
      181 aagctgctca tgaactccga gcaacgcatc aaccggatca tgggctttca caggcccggg
      241 agcggcgcgg aagaagaaaa tcaaacaaag tcaaagccac tggacagtga catactgaat
      301 cccctcggcg ttccttccgt ttccaagagg gtagtgcttg gcgattcagt cgatggagga
      361 gtaactgact accagcccag tggtggcgcc gacatcaggg gagcccagct gggagacaaa
      421 ctggactcat tcattaaagc accagagtgc agtagcaagg atggagttga gcttcggcag
      481 cggaacagag gtgacctgac ggcagactcg gccccgaggg gttctcacca cggcctagaa
      541 cagtacctct ccagattcga agaagcaatg aagttgcgca aacagctgat cagcgagaag
      601 cccagccagg aagatggacg gacgacggaa gagtttgact cttttcgaat atttcgactg
      661 gtggggtgcg ccctgcttgc tcttgttgtc cgagcttttg tttgcaaata tttgtctata
      721 ttcgctccat ttcttacttt gcaacttgcg tacatgggac tgtacaaata ttttcctaag
      781 ggtgagaaga aggtaaagac gacagtgctg accgccgcac tgttgctgtc cgggattccg
      841 gctgaggtga taaaccggtc catggacacc tatagcaaga tgggtgaggt cttcacggac
      901 ctctgcgtct acttcttcac cttcatattc tgccacgaag tgcttgagta ctggggtccg
      961 gaagtgccct gaaacctgag gaacttggaa gtttacgagt gaaaactact tcccttctac
     1021 actgcagtgt ctctaaaggg ggcaaatcgg tttataactt catcaaattc tttggcttta
     1081 cagaaaaccc agttaatcgt ttccccgatt taaaagggtt gaatttctat cagtccaggt
     1141 ctgagttacc acatagggta acaatggcat taacaatttt tcttgtttaa ttagaagtcc
     1201 agccttacac ctctccccta atgtctgaga tttgtgaccc cccttacagg cccaggctgg
     1261 tacttgtaag ggaccagacg gacaggtctc agctggccta aaggcctaaa ccttgtattt
     1321 gtgtcattcc ttcctgagaa atgaaaccat cctaaaaata aagcaaatgg aactgaa
//
